Branching out: mechanisms of dendritic arborization
Open accessAbstract
Type-specific dendrite morphology is a hallmark of the neuron and has important functional implications in determining what signals a neuron receives and how these signals are integrated. During the past two decades, studies on dendritic arborization neurons in Drosophila melanogaster have started to identify mechanisms of dendrite morphogenesis that may have broad applicability to vertebrate species. Transcription factors, receptor-ligand interactions, various signalling pathways, local translational machinery, cytoskeletal elements, Golgi outposts and endosomes have been identified as contributors to the organization of dendrites of individual neurons and the placement of these dendrites in the neuronal circuitry. Further insight into these mechanisms will improve our understanding of how the nervous system functions and might help to identify the underlying causes of some neurological and neurodevelopmental disorders.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Dendritic morphogenesis, synaptogenesis and continued activity-dependent remodelling of synaptic connections are critical for the development and maintenance of functional neuronal networks.
“Dendritic morphogenesis, synaptogenesis and continued activity-dependent remodelling of synaptic connections are critical for the development and maintenance of functional neuronal networks.11, 12, 13, 14, 15”
From The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines (2014) · cites this paper as [11]
The section on dendrite morphogenesis says that neurons coordinate their dendritic fields, and the section on synaptic proteins links dendrite morphology with synaptic function (page numbers not supplied). The review thus supports the importance of dendritic development to neuronal circuitry, but it does not establish the claim about synaptogenesis and continued activity-dependent remodelling of synaptic connections. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
RHO GTPASES: Biochemistry and Biology
Jaffe, A. B., & Hall, A. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.020604.150721 · Cited by 3,009 · see citing works
Lee, T., & Luo, L. (1999) · Neuron · doi:10.1016/s0896-6273(00)80701-1 · Cited by 2,540 · see citing works
Experience-dependent structural synaptic plasticity in the mammalian brain
Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2699 · Cited by 1,934 · see citing works
Advances in autism genetics: on the threshold of a new neurobiology
Abrahams, B. S., & Geschwind, D. H. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2346 · Cited by 1,866 · see citing works
Pyramidal neurons: dendritic structure and synaptic integration
Spruston, N. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2286 · Cited by 1,688 · see citing works
Intellectual ability and cortical development in children and adolescents
Shaw, P., Greenstein, D., Lerch, J., Clasen, L., Lenroot, R., Gogtay, N., Evans, A., Rapoport, J., & Giedd, J. (2006) · Nature · doi:10.1038/nature04513 · Cited by 1,543 · see citing works
Long-term dendritic spine stability in the adult cortex
Grutzendler, J., Kasthuri, N., & Gan, W.-B. (2002) · Nature · doi:10.1038/nature01276 · Cited by 1,198 · cited 1× · see citing works
“Extended time-lapse analyses of mouse cortical neurons have revealed that, following a period of juvenile plasticity during which neurons establish normal dendritic fields, dendrites become stable with most neurons maintaining their dendritic fields for the remainder of their lifespa”
BackgroundDrosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity
Schmucker, D., Clemens, J. C., Shu, H., Worby, C. A., Xiao, J. Y., Muda, M., Dixon, J. E., & Zipursky, S. L. (2000) · Cell · doi:10.1016/s0092-8674(00)80878-8 · Cited by 1,105 · see citing works
Functional architecture of the mammalian retina
Wässle, H., & Boycott, B. B. (1991) · Physiological Reviews · doi:10.1152/physrev.1991.71.2.447 · Cited by 1,093 · see citing works
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
Mei, L., & Xiong, W.-C. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2392 · Cited by 1,030 · see citing works
Neurotrophins regulate dendritic growth in developing visual cortex
McAllister, A. K., Lo, D. C., & Katz, L. C. (1995) · Neuron · doi:10.1016/0896-6273(95)90171-x · Cited by 959 · see citing works
BI-DIRECTIONAL PROTEIN TRANSPORT BETWEEN THE ER AND GOLGI
Lee, M., Miller, E. A., Goldberg, J. D., Orci, L., & Schekman, R. W. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.105307 · Cited by 909 · see citing works
The many faces of actin: matching assembly factors with cellular structures
Chhabra, E. S., & Higgs, H. N. (2007) · Nature Cell Biology · doi:10.1038/ncb1007-1110 · Cited by 744 · see citing works
Baas, P. W., Deitch, J. S., Black, M. M., & Banker, G. A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.21.8335 · Cited by 742 · see citing works
Dendritic Anomalies in Disorders Associated with Mental Retardation
Kaufmann, W. E. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.981 · Cited by 733 · see citing works
Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia
Garey, L. J., Ong, W., Patel, T. S., Kanani, M., Davis, A., Mortimer, A. M., Barnes, T., & Hirsch, S. R. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.65.4.446 · Cited by 719 · see citing works
Craig, A. M., & Banker, G. A. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.001411 · Cited by 678 · see citing works
Actin Cytoskeleton Regulation in Neuronal Morphogenesis and Structural Plasticity
Luo, L. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.031802.150501 · Cited by 658 · see citing works
Hippo signaling in organ size controlPreprint
Pan, D. (2007) · Genes & Development · doi:10.1101/gad.1536007 · Cited by 648 · see citing works
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity
Jaworski, J., Kapitein, L. C., Gouveia, S. M., Dortland, B. R., Wulf, P. S., Grigoriev, I., Camera, P., Spangler, S. A., Di Stefano, P., Demmers, J., et al. (2009) · Neuron · doi:10.1016/j.neuron.2008.11.013 · Cited by 643 · see citing works
Bourgeron, T. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.06.003 · Cited by 637 · see citing works
Activity-dependent regulation of dendritic growth and patterning
Wong, R. O. L., & Ghosh, A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn941 · Cited by 635 · see citing works
A genome-wide linkage and association scan reveals novel loci for autism
The Gene Discovery Project of Johns Hopkins & the Autism Consortium, Weiss, L. A., & Arking, D. E. (2009) · Nature · doi:10.1038/nature08490 · Cited by 619 · see citing works
Molecular mechanisms of dendritic spine morphogenesis
Tada, T., & Sheng, M. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.12.001 · Cited by 615 · see citing works
The Autistic Neuron: Troubled Translation?
Kelleher, R. J., & Bear, M. F. (2008) · Cell · doi:10.1016/j.cell.2008.10.017 · Cited by 598 · see citing works
Compartmentalized dendritic plasticity and input feature storage in neurons
Losonczy, A., Makara, J. K., & Magee, J. C. (2008) · Nature · doi:10.1038/nature06725 · Cited by 598 · see citing works
Tiling of theDrosophilaepidermis by multidendritic sensory neurons
Grueber, W. B., Jan, L. Y., & Jan, Y. N. (2002) · Development · doi:10.1242/dev.129.12.2867 · Cited by 589 · see citing works
Self-citationRegulation of Dendritic Morphogenesis by Ras–PI3K–Akt–mTOR and Ras–MAPK Signaling Pathways
Kumar, V., Zhang, M.-X., Swank, M. W., Kunz, J., & Wu, G.-Y. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2284-05.2005 · Cited by 588 · see citing works
Jaworski, J., Spangler, S. A., Seeburg, D. P., Hoogenraad, C. C., & Sheng, M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2270-05.2005 · Cited by 576 · see citing works
Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth
McAllister, A. K., Katz, L. C., & Lo, D. C. (1997) · Neuron · doi:10.1016/s0896-6273(00)80316-5 · Cited by 570 · see citing works
Histology of the nervous system of man and vertebrates
y Cajal, S. R. (1995) · Cited by 557 · see citing works
Pardo, C. A., & Eberhart, C. G. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00102.x · Cited by 514 · see citing works
Neurogenesis in adult primate neocortex: an evaluation of the evidence
RAKIC, P. T. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn700 · Cited by 491 · see citing works
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
Rosso, S. B., Sussman, D., Wynshaw-Boris, A., & Salinas, P. C. (2005) · Nature Neuroscience · doi:10.1038/nn1374 · Cited by 485 · see citing works
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
Bagni, C., & Greenough, W. T. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1667 · Cited by 475 · see citing works
Wayman, G. A., Impey, S., Marks, D., Saneyoshi, T., Grant, W. F., Derkach, V., & Soderling, T. R. (2006) · Neuron · doi:10.1016/j.neuron.2006.05.008 · Cited by 466 · see citing works
Extreme Diversity among Amacrine Cells: Implications for Function
MacNeil, M. A., & Masland, R. H. (1998) · Neuron · doi:10.1016/s0896-6273(00)80478-x · Cited by 463 · see citing works
Calcium Regulation of Dendritic Growth via CaM Kinase IV and CREB-Mediated Transcription
Redmond, L., Kashani, A. H., & Ghosh, A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00737-7 · Cited by 462 · see citing works
β-catenin is critical for dendritic morphogenesis
Yu, X., & Malenka, R. C. (2003) · Nature Neuroscience · doi:10.1038/nn1132 · Cited by 454 · see citing works
Polarized Secretory Trafficking Directs Cargo for Asymmetric Dendrite Growth and Morphogenesis
Horton, A. C., Rácz, B., Monson, E. E., Lin, A. L., Weinberg, R. J., & Ehlers, M. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.005 · Cited by 436 · see citing works
Dindot, S. V., Antalffy, B. A., Bhattacharjee, M. B., & Beaudet, A. L. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm288 · Cited by 418 · see citing works
Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex
Xu, H., Pan, F., Yang, G., & Gan, W. (2007) · Nature Neuroscience · doi:10.1038/nn1883 · Cited by 413 · see citing works
Failure of neuronal homeostasis results in common neuropsychiatric phenotypes
Ramocki, M. B., & Zoghbi, H. Y. (2008) · Nature · doi:10.1038/nature07457 · Cited by 399 · see citing works
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning
Nishiyama, M., Hoshino, A., Tsai, L., Henley, J. R., Goshima, Y., Tessier‐Lavigne, M., Poo, M.-M., & Hong, K. (2003) · Nature · doi:10.1038/nature01751 · Cited by 387 · see citing works
Regulation of Dendritic Development by Neuron-Specific Chromatin Remodeling Complexes
Wu, J. I., Lessard, J. A., Olave, I. A., Qiu, Z., Ghosh, A., Graef, I. A., & Crabtree, G. R. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.021 · Cited by 387 · see citing works
Stochastic spineless expression creates the retinal mosaic for colour vision
Wernet, M. F., Mazzoni, E. O., Çelik, A., Duncan, D. M., Duncan, I., & Desplan, C. (2006) · Nature · doi:10.1038/nature04615 · Cited by 383 · see citing works
Growing Dendrites and Axons Differ in Their Reliance on the Secretory Pathway
Ye, B., Zhang, Y., Song, W., Younger, S. H., Jan, L. Y., & Jan, Y. N. (2007) · Cell · doi:10.1016/j.cell.2007.06.032 · Cited by 381 · see citing works
Self-citationDscam and Sidekick proteins direct lamina-specific synaptic connections in vertebrate retina
Yamagata, M., & Sanes, J. R. (2008) · Nature · doi:10.1038/nature06469 · Cited by 378 · see citing works
Cdh1-APC Controls Axonal Growth and Patterning in the Mammalian Brain
Konishi, Y., Stegmüller, J., Matsuda, T., Bonni, S., & Bonni, A. (2004) · Science · doi:10.1126/science.1093712 · Cited by 363 · see citing works
Hand, R., Bortone, D. S., Mattar, P. A., Nguyen, L., Heng, J. I., Guerrier, S., Boutt, E., Peters, E. C., Barnes, A. P., Parras, C. M., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.08.032 · Cited by 358 · see citing works
Rho GTPases, dendritic structure, and mental retardation
Newey, S. E., Velamoor, V., Govek, E., & Van Aelst, L. (2005) · Journal of Neurobiology · doi:10.1002/neu.20153 · Cited by 351 · see citing works
Dendrite Self-Avoidance Is Controlled by Dscam
Matthews, B. J., Kim, M. E., Flanagan, J. J., Hattori, D., Clemens, J. C., Zipursky, S. L., & Grueber, W. B. (2007) · Cell · doi:10.1016/j.cell.2007.04.013 · Cited by 351 · see citing works
Evidence for dendritic competition in the developing retina
Perry, V. H., & Linden, R. (1982) · Nature · doi:10.1038/297683a0 · Cited by 343 · see citing works
Rac GTPases control axon growth, guidance and branching
Ng, J., Nardine, T. M., Harms, M. B., Tzu, J., Goldstein, A. Y. N., Sun, Y., Dietzl, G., Dickson, B. J., & Luo, L. (2002) · Nature · doi:10.1038/416442a · Cited by 340 · see citing works
Wojtowicz, W. M., Flanagan, J. J., Millard, S. S., Zipursky, S. L., & Clemens, J. C. (2004) · Cell · doi:10.1016/j.cell.2004.08.021 · Cited by 332 · see citing works
Neuronal diversity in the retina
Masland, R. H. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00230-0 · Cited by 320 · see citing works
Grueber, W. B., Jan, L. Y., & Jan, Y. N. (2003) · Cell · doi:10.1016/s0092-8674(03)00160-0 · Cited by 315 · see citing works
Self-citationDendritic territories of cat retinal ganglion cells
Wässle, H., Peichl, L., & Boycott, B. B. (1981) · Nature · doi:10.1038/292344a0 · Cited by 311 · see citing works
Dendritic spine formation and stabilization
Yoshihara, Y., De Roo, M., & Muller, D. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.05.013 · Cited by 292 · see citing works
Activity-Dependent Dynamic Microtubule Invasion of Dendritic Spines
Hu, X., Viesselmann, C., Nam, S., Merriam, E. B., & Dent, E. W. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3074-08.2008 · Cited by 291 · see citing works
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons
Zheng, Y., Wildonger, J., Ye, B., Zhang, Y., Kita, A. M., Younger, S. H., Zimmerman, S., Jan, L. Y., & Jan, Y. N. (2008) · Nature Cell Biology · doi:10.1038/ncb1777 · Cited by 290 · see citing works
Self-citationLee, T., Winter, C. G., Marticke, S., Lee, A. M., & Luo, L. (2000) · Neuron · doi:10.1016/s0896-6273(00)80896-x · Cited by 287 · see citing works
Dendrite Development Regulated by CREST, a Calcium-Regulated Transcriptional Activator
Aizawa, H., Hu, S., Bobb, K., Balakrishnan, K., Ince-Dunn, G., Gurevich, I., Cowan, M., & Ghosh, A. (2004) · Science · doi:10.1126/science.1089845 · Cited by 282 · see citing works
Neurite arborization and mosaic spacing in the mouse retina require DSCAM
Fuerst, P. G., Koizumi, A., Masland, R. H., & Burgess, R. W. (2008) · Nature · doi:10.1038/nature06514 · Cited by 281 · see citing works
Grueber, W. B., Ye, B., Moore, A. W., Jan, L. Y., & Jan, Y. N. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00207-0 · Cited by 274 · see citing works
Self-citationPetanjek, Z., Judas, M., Kostovic, I., & Uylings, H. B. M. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm124 · Cited by 273 · see citing works
Homophilic Dscam Interactions Control Complex Dendrite Morphogenesis
Hughes, M. E., Bortnick, R., Tsubouchi, A., Bäumer, P., Kondo, M., Uemura, T., & Schmucker, D. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.013 · Cited by 265 · see citing works
DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1
Ly, A., Nikolaev, A. Y., Suresh, G., Zheng, Y., Tessier‐Lavigne, M., & Stein, E. (2008) · Cell · doi:10.1016/j.cell.2008.05.030 · Cited by 265 · see citing works
Soba, P., Zhu, S., Emoto, K., Younger, S. H., Yang, S.-J., Yu, H., Lee, T., Jan, L. Y., & Jan, Y. N. (2007) · Neuron · doi:10.1016/j.neuron.2007.03.029 · Cited by 261 · see citing works
Self-citationPlasma membrane expansion: a neuron's Herculean task
Pfenninger, K. H. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2593 · Cited by 257 · see citing works
Mechanisms that Regulate Establishment, Maintenance, and Remodeling of Dendritic Fields
Parrish, J. Z., Emoto, K., Kim, M. D., & Jan, Y. N. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112907 · Cited by 257 · see citing works
Self-citationGeometric and functional organization of cortical circuits
Shepherd, G. M., Stepanyants, A., Bureau, I., Chklovskii, D. B., & Svoboda, K. (2005) · Nature Neuroscience · doi:10.1038/nn1447 · Cited by 257 · see citing works
A CaMKII-NeuroD Signaling Pathway Specifies Dendritic Morphogenesis
Gaudilliere, B. L., Konishi, Y., de la Iglesia, N., Yao, G.-L., & Bonni, A. (2004) · Neuron · doi:10.1016/s0896-6273(03)00841-9 · Cited by 248 · see citing works
Calcium Signaling and the Control of Dendritic Development
Konur, S., & Ghosh, A. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.022 · Cited by 245 · see citing works
Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons
Lein, P. J., Johnson, M. I., Guo, X., Rueger, D. C., & Higgins, D. M. (1995) · Neuron · doi:10.1016/0896-6273(95)90148-5 · Cited by 239 · see citing works
Emoto, K., He, Y., Ye, B., Grueber, W. B., Adler, P. N., Jan, L. Y., & Jan, Y.-N. (2004) · Cell · doi:10.1016/j.cell.2004.09.036 · Cited by 235 · see citing works
Self-citationJossin, Y., & Goffinet, A. M. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00928-07 · Cited by 235 · see citing works
DSCAM and DSCAML1 Function in Self-Avoidance in Multiple Cell Types in the Developing Mouse Retina
Fuerst, P. G., Bruce, F. M., Tian, M., Wei, W., Elstrott, J., Feller, M. B., Erskine, L., Singer, J. H., & Burgess, R. W. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.027 · Cited by 229 · see citing works
Lee, A., Li, W., Xu, K., Bogert, B. A., Su, K., & Gao, F. (2003) · Development · doi:10.1242/dev.00792 · Cited by 229 · see citing works
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking
Hoogenraad, C. C., Milstein, A. D., Ethell, I. M., Henkemeyer, M. J., & Sheng, M. (2005) · Nature Neuroscience · doi:10.1038/nn1487 · Cited by 227 · see citing works
Development of Continuous and Discrete Neural Maps
Luo, L., & Flanagan, J. G. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.014 · Cited by 223 · see citing works
Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport
Liu, Z., Steward, R., & Luo, L. (2000) · Nature Cell Biology · doi:10.1038/35041011 · Cited by 203 · see citing works
Dscam-Mediated Cell Recognition Regulates Neural Circuit Formation
Hattori, D., Millard, S. S., Wojtowicz, W. M., & Zipursky, S. L. (2008) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.24.110707.175250 · Cited by 203 · see citing works
Wang, J., Zugates, C. T., Liang, I. H., Lee, C.-H. J., & Lee, T. (2002) · Neuron · doi:10.1016/s0896-6273(02)00570-6 · Cited by 202 · see citing works
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes
Satoh, D., Sato, D., Tsuyama, T., Saito, M., Ohkura, H., Rolls, M. M., Ishikawa, F., & Uemura, T. (2008) · Nature Cell Biology · doi:10.1038/ncb1776 · Cited by 201 · see citing works
Walsh, C. A., Morrow, E. M., & Rubenstein, J. L. R. (2008) · Cell · doi:10.1016/j.cell.2008.10.015 · Cited by 194 · see citing works
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance.
Emoto, K., Parrish, J. Z., Jan, L. Y., & Jan, Y.-N. (2006) · Nature · doi:10.1038/nature05090 · Cited by 194 · see citing works
Self-citationnanos and pumilio Are Essential for Dendrite Morphogenesis in Drosophila Peripheral Neurons
Ye, B., Petritsch, C. K., Clark, I. E., Gavis, E. R., Jan, L. Y., & Jan, Y. N. (2004) · Current Biology · doi:10.1016/j.cub.2004.01.052 · Cited by 193 · see citing works
Self-citationParrish, J. Z., Kim, M. D., Jan, L. Y., & Jan, Y. N. (2006) · Genes & Development · doi:10.1101/gad.1391006 · Cited by 192 · see citing works
Self-citationA Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons
Kim, A. H., Puram, S. V., Bilimoria, P. M., Ikeuchi, Y., Keough, S., Wong, M., Rowitch, D. H., & Bonni, A. (2009) · Cell · doi:10.1016/j.cell.2008.11.050 · Cited by 189 · see citing works
Jinushi-Nakao, S., Arvind, R., Amikura, R. M., Kinameri, E., Liu, A. W., & Moore, A. W. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.031 · Cited by 182 · see citing works
Dscam and DSCAM: complex genes in simple animals, complex animals yet simple genesPreprint
Schmucker, D., & Chen, B. (2009) · Genes & Development · doi:10.1101/gad.1752909 · Cited by 178 · see citing works
Dendritic patterning by Dscam and synaptic partner matching in the Drosophila antennal lobe
Zhu, H., Hummel, T., Clemens, J. C., Berdnik, D., Zipursky, S. L., & Luo, L. (2006) · Nature Neuroscience · doi:10.1038/nn1652 · Cited by 175 · see citing works
Regulation of Dendritic Branching and Spine Maturation by Semaphorin3A-Fyn Signaling
Morita, A., Yamashita, N., Sasaki, Y., Uchida, Y., Nakajima, O., Nakamura, F., Yagi, T., Taniguchi, M., Usui, H., Katoh‐Semba, R., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5453-05.2006 · Cited by 174 · see citing works
Embryonic Origins of a Motor System: Motor Dendrites Form a Myotopic Map in Drosophila
Landgraf, M., Jeffrey, V., Fujioka, M., Jaynes, J. B., & Bate, M. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000041 · Cited by 173 · see citing works
Dijkhuizen, P., & Ghosh, A. (2005) · Journal of Neurobiology · doi:10.1002/neu.20100 · Cited by 171 · see citing works
Uncoupling Dendrite Growth and Patterning: Single-Cell Knockout Analysis of NMDA Receptor 2B
Espinosa, J. S., Wheeler, D. G., Tsien, R. W., & Luo, L. (2009) · Neuron · doi:10.1016/j.neuron.2009.03.006 · Cited by 171 · see citing works
Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development
Wynshaw-Boris, A. J. (2007) · Clinical Genetics · doi:10.1111/j.1399-0004.2007.00888.x · Cited by 169 · see citing works
Lin, B., Wang, S. W., & Masland, R. H. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.002 · Cited by 167 · see citing works
Parrish, J. Z., Xu, P., Kim, C. C., Jan, L. Y., & Jan, Y. N. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.006 · Cited by 167 · see citing works
Self-citationDSCAM functions as a netrin receptor in commissural axon pathfinding
Liu, G., Li, W., Wang, L., Kar, A. N., Guan, K., Rao, Y., & Wu, J. Y. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811083106 · Cited by 166 · see citing works
Komiyama, T., Sweeney, L. B., Schuldiner, O., García, K. C., & Luo, L. (2007) · Cell · doi:10.1016/j.cell.2006.12.028 · Cited by 166 · see citing works
Sagasti, A., Guido, M. R., Raible, D. W., & Schier, A. F. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.048 · Cited by 162 · see citing works
Polarity and intracellular compartmentalization of Drosophila neurons
Rolls, M. M., Satoh, D., Clyne, P. J., Henner, A. L., Uemura, T., & Doe, C. Q. (2007) · Neural Development · doi:10.1186/1749-8104-2-7 · Cited by 161 · see citing works
Dendritic stability in the adult olfactory bulb
Mizrahi, A., & Katz, L. C. (2003) · Nature Neuroscience · doi:10.1038/nn1133 · Cited by 161 · see citing works
From Lineage to Wiring Specificity
Komiyama, T., Johnson, W. A., Luo, L., & Jefferis, G. S. X. E. (2003) · Cell · doi:10.1016/s0092-8674(03)00030-8 · Cited by 155 · see citing works
Transmitting on actin: synaptic control of dendritic architecture
Schubert, V., & Dotti, C. G. (2007) · Journal of Cell Science · doi:10.1242/jcs.03337 · Cited by 151 · see citing works
Sugimura, K., Yamamoto, M., Niwa, R., Satoh, D., Goto, S., Taniguchi, M., Hayashi, S., & Uemura, T. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-09-03752.2003 · Cited by 147 · see citing works
Sweeney, L. B., Couto, A., Chou, Y.-H., Berdnik, D., Dickson, B. J., Luo, L., & Komiyama, T. (2007) · Neuron · doi:10.1016/j.neuron.2006.12.022 · Cited by 147 · see citing works
Secretory trafficking in neuronal dendrites
Horton, A. C., & Ehlers, M. (2004) · Nature Cell Biology · doi:10.1038/ncb0704-585 · Cited by 146 · see citing works
Huang, X., Powell‐Coffman, J. A., & Jin, Y. (2004) · Development · doi:10.1242/dev.00959 · Cited by 145 · see citing works
Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia
Karlsgodt, K. H., Sun, D., Jimenez, A. M., Lutkenhoff, E. S., Willhite, R., van Erp, T. G. M., & Cannon, T. D. (2008) · Development and Psychopathology · doi:10.1017/s095457940800062x · Cited by 145 · see citing works
Dscam2 mediates axonal tiling in the Drosophila visual system
Millard, S. S., Flanagan, J. J., Pappu, K. S., Wu, W., & Zipursky, S. L. (2007) · Nature · doi:10.1038/nature05855 · Cited by 145 · see citing works
Activity-Independent Regulation of Dendrite Patterning by Postsynaptic Density Protein PSD-95
Charych, E. I., Akum, B. F., Goldberg, J. S., Jörnsten, R. J., Rongo, C., Zheng, J. Q., & Firestein, B. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2379-06.2006 · Cited by 141 · see citing works
Hippocampal Abnormalities and Enhanced Excitability in a Murine Model of Human Lissencephaly
Fleck, M. W., Hirotsune, S., Gambello, M. J., Phillips‐Tansey, E., Suares, G., Mervis, R. F., Wynshaw-Boris, A. J., & McBain, C. J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-07-02439.2000 · Cited by 138 · see citing works
Small GTPase Cdc42 Is Required for Multiple Aspects of Dendritic Morphogenesis
Scott, E. K., Reuter, J. E., & Luo, L. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03118.2003 · Cited by 134 · see citing works
Kim, M. D., Jan, L. Y., & Jan, Y. N. (2006) · Genes & Development · doi:10.1101/gad.1459706 · Cited by 130 · see citing works
Self-citationHeritability of Changes in Brain Volume Over Time in Twin Pairs Discordant for Schizophrenia
Brans, R. G. H., van Haren, N. E. M., van Baal, G. C. M., Schnack, H. G., Kahn, R. S., & Pol, H. E. H. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.11.1259 · Cited by 129 · see citing works
Dscam guides embryonic axons by Netrin-dependent and -independent functions
Andrews, G. L., Tanglao, S., Farmer, W. T., Morin, S., Brotman, S. J., Berberoglu, M. A., Price, H., Fernandez, G. C. J., Mastick, G. S., Charron, F., et al. (2008) · Development · doi:10.1242/dev.023739 · Cited by 128 · see citing works
A Cost–Benefit Analysis of Neuronal Morphology
Wen, Q., & Chklovskii, D. B. (2008) · Journal of Neurophysiology · doi:10.1152/jn.00280.2007 · Cited by 126 · see citing works
Olson, E. C., Kim, S., & Walsh, C. A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3000-05.2006 · Cited by 126 · see citing works
Sfakianos, M. K., Eisman, A. S., Gourley, S. L., Bradley, W. D., Scheetz, A. J., Settleman, J. E., Taylor, J. R., Greer, C. A., Williamson, A., & Koleske, A. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0793-07.2007 · Cited by 126 · see citing works
Mechanosensory neurite termination and tiling depend on SAX-2 and the SAX-1 kinase.
Gallegos, M. E., & Bargmann, C. I. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.021 · Cited by 124 · see citing works
Vessey, J. P., Macchi, P., Stein, J. M., Mikl, M., Hawker, K. N., Vogelsang, P., Wieczorek, K., Vendra, G., Riefler, J., Tübing, F., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804583105 · Cited by 123 · see citing works
The Coiled-Coil Protein Shrub Controls Neuronal Morphogenesis in Drosophila
Sweeney, N. T., Brenman, J. E., Jan, Y. N., & Gao, F. (2006) · Current Biology · doi:10.1016/j.cub.2006.03.067 · Cited by 120 · see citing works
Self-citationCytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization
Chihara, T., Luginbuhl, D. J., & Luo, L. (2007) · Nature Neuroscience · doi:10.1038/nn1910 · Cited by 118 · see citing works
Convergent CaMK and RacGEF signals control dendritic structure and function
Penzes, P., Cahill, M. E., Jones, K. A., & Srivastava, D. P. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.07.002 · Cited by 118 · see citing works
Molecules and mechanisms of dendrite development in Drosophila
Corty, M. M., Matthews, B. J., & Grueber, W. B. (2009) · Development · doi:10.1242/dev.014423 · Cited by 114 · see citing works
A glimmer of light for neuropsychiatric disorders
Hyman, S. E. (2008) · Nature · doi:10.1038/nature07454 · Cited by 110 · see citing works
RhoA Regulates Dendrite Branching in Hippocampal Neurons by Decreasing Cypin Protein Levels
Chen, H., & Firestein, B. L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0872-07.2007 · Cited by 107 · see citing works
Peng, Y., He, S., Marie, H., Zeng, S.-Y., Ma, J., Tan, Z.-J., Lee, S. Y., Malenka, R. C., & Yu, X. (2009) · Neuron · doi:10.1016/j.neuron.2008.11.015 · Cited by 107 · see citing works
Transient neurites of retinal horizontal cells exhibit columnar tiling via homotypic interactions
Huckfeldt, R. M., Schubert, T., Morgan, J., Godinho, L., Cristo, G. D., Huang, Z. J., & Wong, R. (2008) · Nature Neuroscience · doi:10.1038/nn.2236 · Cited by 107 · see citing works
Sugimura, K., Satoh, D., Estes, P. A., Crews, S. T., & Uemura, T. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.016 · Cited by 103 · see citing works
Li, W., Wang, F., Menut, L., & Gao, F. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.040 · Cited by 102 · see citing works
Intrinsic neuronal regulation of axon and dendrite growth
Goldberg, J. L. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.08.012 · Cited by 100 · see citing works
A mosaic genetic screen for genes necessary forDrosophilamushroom body neuronal morphogenesis
Reuter, J. E., Nardine, T. M., Penton, A. L., Billuart, P., Scott, E. K., Usui, T., Uemura, T., & Luo, L. (2003) · Development · doi:10.1242/dev.00319 · Cited by 97 · see citing works
Quitsch, A., Berhörster, K., Liew, C. W., Richter, D., & Kreienkamp, H.-J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2699-04.2005 · Cited by 95 · see citing works
Li, H.-L., Huang, B. S., Vishwasrao, H. D., Sutedja, N. A., Chen, W., Jin, I., Hawkins, R. D., Bailey, C. H., & Kandel, E. R. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.010 · Cited by 90 · see citing works
Hattori, Y., Sugimura, K., & Uemura, T. (2007) · Genes to Cells · doi:10.1111/j.1365-2443.2007.01107.x · Cited by 84 · see citing works
Mauss, A. S., Tripodi, M., Evers, J. F., & Landgraf, M. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000200 · Cited by 82 · see citing works
The RNA binding protein CPEB regulates dendrite morphogenesis and neuronal circuit assembly in vivo
Bestman, J. E., & Cline, H. T. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806296105 · Cited by 81 · see citing works
Control of multidendritic neuron differentiation in Drosophila: The role of Collier
Crozatier, M., & Vincent, A. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2007.12.030 · Cited by 81 · see citing works
Remodeling dendrites during insect metamorphosis
Williams, D. W., & Truman, J. W. (2005) · Journal of Neurobiology · doi:10.1002/neu.20151 · Cited by 76 · see citing works
Parrish, J. Z., Emoto, K., Jan, L. Y., & Jan, Y. N. (2007) · Genes & Development · doi:10.1101/gad.1514507 · Cited by 76 · see citing works
Self-citationIntrinsic Control of Precise Dendritic Targeting by an Ensemble of Transcription Factors
Komiyama, T., & Luo, L. (2007) · Current Biology · doi:10.1016/j.cub.2006.11.067 · Cited by 73 · see citing works
Spatial Regulation of nanos Is Required for Its Function in Dendrite Morphogenesis
Brechbiel, J. L., & Gavis, E. R. (2008) · Current Biology · doi:10.1016/j.cub.2008.04.033 · Cited by 70 · see citing works
Koike-Kumagai, M., Yasunaga, K.-I., Morikawa, R., Kanamori, T., & Emoto, K. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.312 · Cited by 69 · see citing works
The origin recognition core complex regulates dendrite and spine development in postmitotic neurons
Huang, Z. D., Zang, K., & Reichardt, L. F. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200505075 · Cited by 63 · see citing works
Brierley, D. J., Blanc, E., Reddy, O. V., VijayRaghavan, K., & Williams, D. W. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000199 · Cited by 63 · see citing works
Slit and Robo control the development of dendrites inDrosophilaCNS
Furrer, M.-P., Vasenkova, I. A., Kamiyama, D., Rosado, Y., & Chiba, A. (2007) · Development · doi:10.1242/dev.02882 · Cited by 62 · see citing works
Patterning and organization of motor neuron dendrites in the Drosophila larva
Kim, M. D., Wen, Y., & Jan, Y. N. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.09.041 · Cited by 61 · see citing works
Self-citationRho GTPases and Phosphoinositide 3-Kinase Organize Formation of Branched Dendrites
Leemhuis, J., Boutillier, S., Barth, H., Feuerstein, T. J., Brock, C., Nürnberg, B., Aktories, K., & Meyer, D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307066200 · Cited by 59 · see citing works
Dscam-mediated repulsion controls tiling and self-avoidance
Millard, S. S., & Zipursky, S. L. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.05.005 · Cited by 56 · see citing works
Slit and Robo regulate dendrite branching and elongation of space-filling neurons in Drosophila
Dimitrova, S., Reissaus, A., & Tavosanis, G. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.08.028 · Cited by 54 · see citing works
Gan, W., & Macagno, E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03243.1995 · Cited by 49 · see citing works
General design principle for scalable neural circuits in a vertebrate retina
Lee, S., & Stevens, C. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705469104 · Cited by 45 · see citing works
Actin Filament-Stabilizing Protein Tropomyosin Regulates the Size of Dendritic Fields
Li, W.-J., & Gao, F. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06171.2003 · Cited by 40 · see citing works
ネズミのスタウフェン1に対する機能消失対立遺伝子は,樹状突起のStaufen1‐RNP配送や樹状突起棘の形態形成の障害を誘導する
John, P. V., Paolo, M., Joel, M. S., Martin, M., Kelvin, N. H., Petra, V., Krzysztof, W., Vendra, G., Riefler, J., Fabian, T., et al. (2008) · Cited by 36 · see citing works
The role of cytoplasmic dynein in the human brain developmental disease lissencephaly
Vallee, R. B., Faulkner, N. E., & Tai, C. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00011-2 · Cited by 34 · see citing works
Adhesion molecules in establishing retinal circuitry
Fuerst, P. G., & Burgess, R. W. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.07.013 · Cited by 27 · see citing works
Competition during innervation of embryonic amphibian head skin
Kitson, D. L., & Roberts, A. (1983) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1983.0025 · Cited by 26 · see citing works
Cardno, A. G., & Gottesman, I. I. (2000) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(200021)97:1
Flagged first, then by citations
Research works printed but not linked: 2
- [12]Bestman J Silva JSD Cline HT Stuart G Spruston N Häusser M Dendrites 69 94 Oxford University Press Oxford 2008
- [13]Polleux F Ghosh A Stuart G Spruston N Häusser M Dendrites 95 115 Oxford University Press Oxford 2008
Cited by
Sorted by citations
Gao, S., Zhou, M., Wang, Y., Cheng, J., Yachi, H., & Wang, J. (2018) · IEEE Transactions on Neural Networks and Learning Systems · doi:10.1109/tnnls.2018.2846646 · Cited by 700 · see citing works
Functional architecture of the retina: Development and disease
Hoon, M., Okawa, H., Santina, L. D., & Wong, R. (2014) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2014.06.003 · Cited by 577 · see citing works
The single dendritic branch as a fundamental functional unit in the nervous system
Branco, T., & Häusser, M. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.07.009 · Cited by 355 · see citing works
Fieblinger, T., Graves, S. M., Sebel, L. E., Alcacer, C., Plotkin, J. L., Gertler, T. S., Chan, C. S., Heiman, M., Greengard, P., Cenci, M. A., et al. (2014) · Nature Communications · doi:10.1038/ncomms6316 · Cited by 293 · see citing works
Precise temporal regulation of alternative splicing during neural development
Weyn‐Vanhentenryck, S. M., Feng, H., Ustianenko, D., Duffié, R., Yan, Q., Jacko, M., Martinez, J. C., Goodwin, M., Zhang, X., Hengst, U., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04559-0 · Cited by 271 · see citing works
Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity
Gilbert, J. P., & Man, H. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00359 · Cited by 274 · see citing works
Han, C., Jan, L. Y., & Jan, Y. N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106386108 · Cited by 280 · see citing works
Self-citationShaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions
Cserép, C., Pósfai, B., & Dénes, Á. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.007 · Cited by 256 · see citing works
Intellectual disability and autism spectrum disorders: Causal genes and molecular mechanisms
Srivastava, A. K., & Schwartz, C. E. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.02.015 · Cited by 251 · see citing works
Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators
Li, J., Han, S., Li, H., Udeshi, N. D., Svinkina, T., Mani, D. R., Xu, C., Guajardo, R., Xie, Q., Li, T., et al. (2020) · Cell · doi:10.1016/j.cell.2019.12.029 · Cited by 204 · see citing works
Development of Dendritic Form and Function
Lefebvre, J. L., Sanes, J. R., & Kay, J. N. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013020 · Cited by 226 · see citing works
Developmental regulation of axon branching in the vertebrate nervous system
Gibson, D. A., & Ma, L. (2010) · Development · doi:10.1242/dev.046441 · Cited by 207 · see citing works
Ramkumar, A., Jong, B. Y., & Ori-McKenney, K. M. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24599 · Cited by 194 · see citing works
A Topological Representation of Branching Neuronal Morphologies
Kanari, L., Dłotko, P., Scolamiero, M., Levi, R., Shillcock, J. C., Hess, K. P., & Markram, H. (2017) · Neuroinformatics · doi:10.1007/s12021-017-9341-1 · Cited by 193 · see citing works
Mechanisms of developmental neurite pruning
Schuldiner, O., & Yaron, A. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1729-6 · Cited by 190 · see citing works
Pathania, M., Davenport, E. C., Muir, J., Sheehan, D. F., López-Doménech, G., & Kittler, J. T. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.16 · Cited by 189 · see citing works
Dean, J. M., McClendon, E., Hansen, K., Azimi-Zonooz, A., Chen, K. Y., Riddle, A., Gong, X., Sharifnia, E., Hagen, M. W., Ahmad, T., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3004669 · Cited by 188 · see citing works
Han, C., Wang, D., Soba, P., Zhu, S., Lin, X., Jan, L. Y., & Jan, Y.-N. (2012) · Neuron · doi:10.1016/j.neuron.2011.10.036 · Cited by 168 · see citing works
Self-citationLópez‐Doménech, G., Higgs, N., Vaccaro, V., Roš, H., Arancibia‐Cárcamo, I. L., MacAskill, A. F., & Kittler, J. T. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.09.004 · Cited by 174 · see citing works
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex
de Anda, F. C., Rosário, A. L., Durak, O., Tran, T. S., Gräff, J., Meletis, K., Rei, D., Soda, T., Madabhushi, R., Ginty, D. D., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3141 · Cited by 171 · see citing works
Garrett, A. M., Schreiner, D., Lobas, M. A., & Weiner, J. A. (2012) · Neuron · doi:10.1016/j.neuron.2012.01.028 · Cited by 165 · see citing works
An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging
Yu, D., Gustafson, W. C., Han, C., Lafaye, C., Noirclerc‐Savoye, M., Ge, W., Thayer, D. A., Huang, H., Kornberg, T. B., Royant, A., et al. (2014) · Nature Communications · doi:10.1038/ncomms4626 · Cited by 165 · see citing works
Self-citationThe FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes
Schwenk, B. M., Lang, C. M., Hogl, S., Tahirović, S., Orozco, D., Rentzsch, K., Lichtenthaler, S. F., Hoogenraad, C. C., Capell, A., Haass, C., et al. (2013) · The EMBO Journal · doi:10.1002/embj.201385857 · Cited by 165 · see citing works
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
Wong, H. H., Lin, J. Q., Ströhl, F., Roque, C. G., Cioni, J.-M., Cagnetta, R., Turner-Bridger, B., Laine, R. F., Harris, W. A., Kaminski, C. F., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.016 · Cited by 165 · see citing works
An Extracellular Adhesion Molecule Complex Patterns Dendritic Branching and Morphogenesis
Dong, X., Liu, O. W., Howell, A. S., & Shen, K. (2013) · Cell · doi:10.1016/j.cell.2013.08.059 · Cited by 163 · see citing works
Role of leucine-rich repeat proteins in the development and function of neural circuits.
de Wit, J., Hong, W.-Z., Luo, L.-Q., & Ghosh, A. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154111 · Cited by 168 · see citing works
Cellular and molecular mechanisms regulating neuronal growth by brain‐derived neurotrophic factor
González‐Gutiérrez, A., Moya‐Alvarado, G., González-Billault, C. E., & Bronfman, F. C. (2016) · Cytoskeleton · doi:10.1002/cm.21312 · Cited by 154 · see citing works
Skin-Derived Cues Control Arborization of Sensory Dendrites in Caenorhabditis elegans
Salzberg, Y., Díaz-Balzac, C. A., Ramírez-Suárez, N. J., Attreed, M., Tecle, E., Desbois, M., Kaprielian, Z., & Bülow, H. E. (2013) · Cell · doi:10.1016/j.cell.2013.08.058 · Cited by 152 · see citing works
Urbańska, M., Góźdź, A., Swiech, L. J., & Jaworski, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.374405 · Cited by 149 · see citing works
Ouyang, Q., Lizarraga, S. B., Schmidt, M., Yang, U., Gong, J., Ellisor, D., Kauer, J. A., & Morrow, E. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.07.043 · Cited by 147 · see citing works
Self-referential forces are sufficient to explain different dendritic morphologies
Memelli, H., Torben-Nielsen, B., & Kozloski, J. (2013) · Front. Neuroinform. · doi:10.3389/fninf.2013.00001 · Cited by 127 · see citing works
Zhou, B., Cai, Q., Xie, Y., & Sheng, Z. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.06.010 · Cited by 141 · see citing works
Intrinsic and Extrinsic Mechanisms of Dendritic Morphogenesis
Dong, X., Shen, K., & Bülow, H. E. (2014) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021014-071746 · Cited by 139 · see citing works
Ultanir, S. K., Hertz, N. T., Li, G., Ge, W.-P., Burlingame, A. L., Pleasure, S. J., Shokat, K. M., Jan, L. Y., & Jan, Y.-N. (2012) · Neuron · doi:10.1016/j.neuron.2012.01.019 · Cited by 131 · see citing works
Self-citationEmerging roles of the neuronal nucleolus
Hetman, M., & Pietrzak, M. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.01.002 · Cited by 127 · see citing works
Budelli, G., Ni, L., Berciu, C., van Giesen, L., Knecht, Z. A., Chang, E. C., Kaminski, B., Silbering, A. F., Samuel, A., Klein, M., et al. (2019) · Neuron · doi:10.1016/j.neuron.2018.12.022 · Cited by 126 · see citing works
Centrosomin represses dendrite branching by orienting microtubule nucleation
Yalgin, C., Ebrahimi, S., Delandre, C., Yoong, L. F., Akimoto, S., Tran, H., Amikura, R. M., Spokony, R. F., Torben-Nielsen, B., White, K. P., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4099 · Cited by 124 · see citing works
Kim, M. E., Shrestha, B. R., Blazeski, R., Mason, C. A., & Grueber, W. B. (2012) · Neuron · doi:10.1016/j.neuron.2011.10.033 · Cited by 123 · see citing works
Humanized Foxp2 specifically affects cortico-basal ganglia circuits
Reimers-Kipping, S., Hevers, W., Pääbo, S., & Enard, W. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.11.042 · Cited by 122 · see citing works
Smith, C. J., O’Brien, T., Chatzigeorgiou, M., Spencer, W. C., Feingold-Link, E., Husson, S. J., Hori, S., Mitani, S., GOTTSCHALK, A. R., Schafer, W. R., et al. (2013) · Neuron · doi:10.1016/j.neuron.2013.05.009 · Cited by 122 · see citing works
Axon and dendrite pruning in Drosophila
Yu, F., & Schuldiner, O. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.04.005 · Cited by 118 · see citing works
Age, plasticity, and homeostasis in childhood brain disorders
Dennis, M., Spiegler, B. J., Juranek, J. J., Bigler, E. D., Snead, O. C., & Fletcher, J. M. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.09.010 · Cited by 119 · see citing works
Branching Morphogenesis: From Cells to Organs and BackPreprint
Ochoa‐Espinosa, A., & Affolter, M. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008243 · Cited by 117 · see citing works
Mishra-Gorur, K., Çağlayan, A. O., Schaffer, A. E., Chabu, C. Y., Henegariu, O., Vonhoff, F., Akgumus, G. T., Nishimura, S., Han, W., Tu, S., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.12.014 · Cited by 114 · see citing works
The role of small GTPases in neuronal morphogenesis and polarity
González-Billault, C. E., Muñoz-LLancao, P., Henríquez, D. R., Wojnacki, J., Conde, C. B., & Cáceres, A. (2012) · Cytoskeleton · doi:10.1002/cm.21034 · Cited by 112 · see citing works
Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase
Suo, L., Lu, H., Ying, G., Capecchi, M. R., & Wu, Q. (2012) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjs034 · Cited by 113 · see citing works
Transcriptional Regulation of Neuronal Polarity and Morphogenesis in the Mammalian Brain
de la Torre-Ubieta, L., & Bonni, A. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.018 · Cited by 109 · see citing works
Matsubara, D., Horiuchi, S.-Y., Shimono, K., Usui, T., & Uemura, T. (2011) · Genes & Development · doi:10.1101/gad.16531611 · Cited by 111 · see citing works
Moya‐Alvarado, G., Tiburcio‐Félix, R., Ibáñez, M. R., Aguirre-Soto, A. A., Guerra, M. V., Wu, C., Mobley, W. C., Perlson, E., & Bronfman, F. C. (2023) · eLife · doi:10.7554/elife.77455 · Cited by 110 · see citing works
Control of Neuronal Morphology by the Atypical Cadherin Fat3
Deans, M. R., Krol, A., Abraira, V. E., Copley, C. O., Tucker, A. F., & Goodrich, L. V. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.026 · Cited by 108 · see citing works
BTBD3 Controls Dendrite Orientation Toward Active Axons in Mammalian Neocortex
Matsui, A., Tran, M., Yoshida, A., Kikuchi, S. S., Mami, U., Ogawa, M., & Shimogori, T. (2013) · Science · doi:10.1126/science.1244505 · Cited by 103 · see citing works
CLIP-170 and IQGAP1 Cooperatively Regulate Dendrite Morphology
Swiech, L. J., Błażejczyk, M., Urbańska, M., Pietruszka, P., Dortland, B. R., Malik, A. R., Wulf, P. S., Hoogenraad, C. C., & Jaworski, J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6582-10.2011 · Cited by 107 · see citing works
Litterman, N. K., Ikeuchi, Y., Gallardo, G., O’Connell, B. C., Sowa, M. E., Gygi, S. P., Harper, J. W., & Bonni, A. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001060 · Cited by 105 · see citing works
Miao, S., Chen, R., Ye, J., Tan, G., Li, S., Zhang, J., Jiang, Y., & Xiong, Z. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2509-12.2013 · Cited by 105 · see citing works
MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling
Ka, M., Jung, E., Mueller, U. W., & Kim, W.-Y. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.09.009 · Cited by 104 · see citing works
A scaling law derived from optimal dendritic wiring
Cuntz, H., Mathy, A., & Häusser, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200430109 · Cited by 101 · see citing works
Cell-intrinsic drivers of dendrite morphogenesis
Puram, S. V., & Bonni, A. (2013) · Development · doi:10.1242/dev.087676 · Cited by 100 · see citing works
The transmembrane LRR protein DMA-1 promotes dendrite branching and growth in C. elegans
Liu, O. W., & Shen, K. (2011) · Nature Neuroscience · doi:10.1038/nn.2978 · Cited by 100 · see citing works
Early Events in Axon/Dendrite Polarization
Cheng, P., & Poo, M. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113618 · Cited by 99 · see citing works
Molecular mechanisms of dendrite morphogenesis
Arikkath, J. (2012) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2012.00061 · Cited by 99 · see citing works
Zipcode Binding Protein 1 Regulates the Development of Dendritic Arbors in Hippocampal Neurons
Perycz, M., Urbanska, A. S., Krawczyk, P. S., Parobczak, K., & Jaworski, J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2387-10.2011 · Cited by 95 · see citing works
Yamashita, N., Ohshima, T., Nakamura, F., Kolattukudy, P. E., Honnorat, J., Mikoshiba, K., & Goshima, Y. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5563-11.2012 · Cited by 95 · see citing works
Warre-Cornish, K. M., Perfect, L., Nagy, R., Duarte, R. R. R., Reid, M. J., Raval, P., Mueller, A., Evans, A., Couch, A. C. M., Ghevaert, C., et al. (2020) · Science Advances · doi:10.1126/sciadv.aay9506 · Cited by 96 · see citing works
A RhoA Signaling Pathway Regulates Dendritic Golgi Outpost Formation
Quassollo, G., Wojnacki, J., Salas, D. A., Gastaldi, L., Marzolo, M., Conde, C. B., Bisbal, M., Couve, A., & Cáceres, A. (2015) · Current Biology · doi:10.1016/j.cub.2015.01.075 · Cited by 93 · see citing works
Larval Defense against Attack from Parasitoid Wasps Requires Nociceptive Neurons
Robertson, J., Tsubouchi, A., & Tracey, W. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078704 · Cited by 93 · see citing works
Gunnewiek, T. M. K., van Hugte, E., Frega, M., Guardia, G. S., Foreman, K., Panneman, D. M., Mossink, B., Linda, K., Keller, J. M., Schubert, D., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107538 · Cited by 90 · see citing works
Dendrite Self-Avoidance Requires Cell-Autonomous Slit/Robo Signaling in Cerebellar Purkinje Cells
Gibson, D. A., Tymanskyj, S. R., Yuan, R., Leung, H. C., Lefebvre, J. L., Sanes, J. R., Chédotal, A., & Ma, L. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.009 · Cited by 89 · see citing works
A conserved juxtacrine signal regulates synaptic partner recognition in C. elegans
Park, J. R., Knezevich, P. L., Wung, W., O'Hanlon, S. N., Goyal, A., Benedetti, K. L., Barsi‐Rhyne, B., Raman, M. M., Mock, N., Bremer, M., et al. (2011) · San José State University ScholarWorks (San Jose State University) · doi:10.1038/nn.3065 · Cited by 2 · see citing works
Weir, R. K., Bauman, M. D., Jacobs, B., & Schumann, C. M. (2017) · The Journal of Comparative Neurology · doi:10.1002/cne.24332 · Cited by 83 · see citing works
Srivastava, D. P., Woolfrey, K. M., Jones, K. A., Anderson, C. T., Smith, K. R., Russell, T. A., Lee, H., Yasvoina, M. V., Wokosin, D. L., Özdi̇nler, P. H., et al. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001350 · Cited by 86 · see citing works
Copf, T. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.04.008 · Cited by 85 · see citing works
RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport
Taylor, C. A., Yan, J., Howell, A. S., Dong, X., & Shen, K. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005695 · Cited by 83 · see citing works
Mohammad, H., Marchisella, F., Ortega‐Martínez, S., Hollós, P., Eerola, K., Komulainen, E., Kulesskaya, N., Freemantle, E., Fagerholm, V., Savontous, E., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.203 · Cited by 86 · see citing works
Light-Induced Structural and Functional Plasticity in Drosophila Larval Visual System
Yuan, Q., Xiang, Y., Yan, Z., Han, C., Jan, L. Y., & Jan, Y. N. (2011) · Science · doi:10.1126/science.1207121 · Cited by 82 · see citing works
Self-citationBlizinsky, K. D., Diaz-Castro, B., Forrest, M. P., Schürmann, B., Bach, A. P., Martin-de-Saavedra, M. D., Wang, L., Csernansky, J. G., Duan, J., & Penzes, P. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1607014113 · Cited by 76 · see citing works
Transcription factors and effectors that regulate neuronal morphology
Santiago, C., & Bashaw, G. J. (2014) · Development · doi:10.1242/dev.110817 · Cited by 81 · see citing works
Dendritic structural plasticity
Tavosanis, G. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20951 · Cited by 84 · see citing works
Fischer, R. S., Lam, P., Anna Huttenlocher, A., & Waterman, C. M. (2018) · Developmental Biology · doi:10.1016/j.ydbio.2018.08.015 · Cited by 79 · see citing works
Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development
Cunningham, C. L., Martínez‐Cerdeño, V., Porras, E. N., Prakash, A. N., Angelastro, J. M., Willemsen, R., Hagerman, P. J., Pessah, I. N., Berman, R. F., & Noctor, S. C. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq432 · Cited by 79 · see citing works
Yoshino, J., Morikawa, R. K., Hasegawa, E., & Emoto, K. (2017) · Current Biology · doi:10.1016/j.cub.2017.06.068 · Cited by 89 · see citing works
Shen, T., Ji, F., Wang, Y., Lei, X., Zhang, D., & Jiao, J. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1295 · Cited by 77 · see citing works
Ultanir, S. K., Yadav, S., Hertz, N. T., Oses-Prieto, J. A., Claxton, S., Burlingame, A. L., Shokat, K. M., Jan, L. Y., & Jan, Y.-N. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.025 · Cited by 75 · see citing works
Self-citationBustos, F. J., Varela‐Nallar, L., Campos, M., Henríquez, B., Phillips, M. A., Opazo, C., Aguayo, L. G., Montecino, M. A., Constantine‐Paton, M., Inestrosa, N. C., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094037 · Cited by 75 · see citing works
Development of larval motor circuits in Drosophila
Kohsaka, H., Okusawa, S., Itakura, Y., Fushiki, A., & Nose, A. (2012) · Development Growth & Differentiation · doi:10.1111/j.1440-169x.2012.01347.x · Cited by 75 · see citing works
Zou, W., Dong, X., Broederdorf, T., Shen, A., Kramer, D. A., Shi, R., Liang, X., Miller, D. M., Xiang, Y. K., Yasuda, R., et al. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.04.008 · Cited by 74 · see citing works
The cellular basis of dendrite pathology in neurodegenerative diseases
Kweon, J. H., Kim, S., & Lee, S. B. (2017) · BMB Reports · doi:10.5483/bmbrep.2017.50.1.131 · Cited by 73 · see citing works
Dendrite architecture organized by transcriptional control of the F-actin nucleator Spire
Ferreira, T., Ou, Y., Li, S. S. Y., Giniger, E., & van Meyel, D. J. (2014) · Development · doi:10.1242/dev.099655 · Cited by 73 · see citing works
Crescenzo, A. H. D., Panoutsopoulos, A. A., Tat, L., Schaaf, Z. A., Racherla, S., Henderson, L., Leung, K., Greene, N. D. E., Green, R., & Zarbalis, K. S. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa248 · Cited by 73 · see citing works
Principles of branch dynamics governing shape characteristics of cerebellar Purkinje cell dendrites
Fujishima, K., Horie, R., Mochizuki, A., & Kengaku, M. (2012) · Development · doi:10.1242/dev.081315 · Cited by 73 · see citing works
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development
Nakagawa, N., Plestant, C., Yabuno-Nakagawa, K., Li, J., Lee, J. C. L., Huang, C.-W., Lee, A., Krupa, O., Adhikari, A., Thompson, S., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.049 · Cited by 67 · see citing works
Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons
Xie, Q., Brbić, M., Horns, F., Kolluru, S. S., Jones, R. C., Li, J., Reddy, A. R., Xie, A., Kohani, S., Li, Z., et al. (2021) · eLife · doi:10.7554/elife.63450 · Cited by 72 · see citing works
Local endocytosis triggers dendritic thinning and pruning in Drosophila sensory neurons
Kanamori, T., Yoshino, J., Yasunaga, K.-I., Dairyo, Y., & Emoto, K. (2015) · Nature Communications · doi:10.1038/ncomms7515 · Cited by 72 · see citing works
Iyer, E. P. R., Iyer, S. C., Sullivan, L. F., Wang, D. Y. Q., Meduri, R., Graybeal, L. L., & Cox, D. N. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072434 · Cited by 72 · see citing works
Straub, J., Konrad, E. D. H., Grüner, J., Toutain, A., Bok, L. A., Cho, M. T., Crawford, H. P., Dubbs, H. A., Douglas, G., Jobling, R., et al. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.11.008 · Cited by 72 · see citing works
Zou, W., Shen, A., Dong, X., Tugizova, M. S., Xiang, Y. K., & Shen, K. (2016) · eLife · doi:10.7554/elife.18345 · Cited by 71 · see citing works
Design principles and developmental mechanisms underlying retinal mosaics
Reese, B. E., & Keeley, P. W. (2014) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12139 · Cited by 71 · see citing works
Tanabe, K., Kani, S., Shimizu, T., Bae, Y., Abe, T., & Hibi, M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3352-10.2010 · Cited by 71 · see citing works
In situ cell-type-specific cell-surface proteomic profiling in mice
Shuster, S. A., Li, J., Chon, U., Sinantha-Hu, M. C., Luginbuhl, D. J., Udeshi, N. D., Carey, D. K., Takeo, Y. H., Xie, Q., Xu, C., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.025 · Cited by 70 · see citing works
Protocadherins branch out: Multiple roles in dendrite development
Keeler, A. B., Molumby, M. J., & Weiner, J. A. (2015) · Cell Adhesion & Migration · doi:10.1080/19336918.2014.1000069 · Cited by 70 · see citing works
Development of the embryonic and larval peripheral nervous system of Drosophila
Singhania, A., & Grueber, W. B. (2014) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.135 · Cited by 69 · see citing works
- Authors
- Jan, Y.-N., & Jan, L. Y.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Jan, Yuh-Nung
- Venue
- Nature Reviews Neuroscience
- Published
- 2010-05
- Volume
- 11
- Issue
- 5
- Pages
- 316-328
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- PMC
- PMC3079328
- OpenAlex
- W2065943966
- Cited by
- 693
- References
- 162
- Citations by year
- 2026: 15 · 2025: 41 · 2024: 24 · 2023: 29 · 2022: 33 · 2021: 41 · 2020: 71 · 2019: 41 · 2018: 45 · 2017: 49 · 2016: 52 · 2015: 38 · 2014: 58 · 2013: 53 · 2012: 53
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Update notices
- erratum (2010-06-01)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institutes of Health
- National Institute of Mental Health (R01MH084234)
- National Institute of Neurological Disorders and Stroke (R37NS040929)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Keywords
- dendritic branching, dendrite morphogenesis, dendritic morphology, Drosophila melanogaster, transcription factors, ligand-receptor interactions, signaling pathways, local translation, cytoskeleton, endosomes, autism spectrum disorder, neurodevelopmental disorders, neural circuits
- MeSH terms
- Animals, Axons, Dendrites, Humans, Models, Neurological, Morphogenesis, Neurons, Signal Transduction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review