Nanotechnology—novel therapeutics for CNS disorders

Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., Belanger, K., Brandes, A. A., Marosi, C., Bogdahn, U., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043330 · Cited by 21,807 · see citing works

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359 · see citing works

Alzheimer’s disease

Querfurth, H. W., & LaFerla, F. M. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0909142 · Cited by 4,569 · see citing works

Tumour stem cells and drug resistance

Dean, M., Fojo, T., & Bates, S. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1590 · Cited by 3,668 · see citing works

Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers

Hartgerink, J. D., Beniash, E., & Stupp, S. I. (2001) · Science · doi:10.1126/science.1063187 · Cited by 3,607 · see citing works

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Yang, F., Lim, G. P., Begum, A. N., Ubeda, O. J., Simmons, M. R., Ambegaokar, S. S., Chen, P. P., Kayed, R., Glabe, C. G., Frautschy, S. A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m404751200 · Cited by 2,336 · see citing works

Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers

Silva, G. A., Czeisler, C. M., Niece, K. L., Beniash, E., Harrington, D. A., Kessler, J. A., & Stupp, S. I. (2004) · Science · doi:10.1126/science.1093783 · Cited by 2,169 · see citing works

Copper, iron and zinc in Alzheimer's disease senile plaques

Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., & Markesbery, W. R. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00092-6 · Cited by 2,120 · see citing works

Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

SantaCruz, K., Lewis, J., Spires, T., Paulson, J., Kotilinek, L., Ingelsson, M., Guimaraes, A., DeTure, M., Ramsden, M., McGowan, E., et al. (2005) · Science · doi:10.1126/science.1113694 · Cited by 2,014 · see citing works

Parkinson's disease

Lees, A. J., Hardy, J., & Revesz, T. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60492-x · Cited by 1,956 · see citing works

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Nunomura, A., Perry, G., Aliev, G., Hirai, K., Takeda, A., Balraj, E. K., Jones, P. K., Ghanbari, H., Wataya, T., Shimohama, S., et al. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.8.759 · Cited by 1,885 · see citing works

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

Tanzi, R. E., & Bertram, L. (2005) · Cell · doi:10.1016/j.cell.2005.02.008 · Cited by 1,849 · see citing works

Levodopa and the Progression of Parkinson's Disease

The Parkinson Study Group (2004) · New England Journal of Medicine · doi:10.1056/nejmoa033447 · Cited by 1,844 · see citing works

Immunological properties of engineered nanomaterials

Dobrovolskaia, M. A., & McNeil, S. E. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.223 · Cited by 1,823 · see citing works

Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering

Yang, F., Ramalingam, M., Wang, S.-J., & Ramakrishna, S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.051 · Cited by 1,803 · see citing works

Synthetic DNA delivery systems

Luo, D., & Saltzman, W. M. (2000) · Nature Biotechnology · doi:10.1038/71889 · Cited by 1,625 · see citing works

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y.-S., et al. (2001) · Neuron · doi:10.1016/s0896-6273(01)00317-8 · Cited by 1,447 · see citing works

Cytotoxicity of Carbon Nanomaterials: Single-Wall Nanotube, Multi-Wall Nanotube, and Fullerene

Jia, G., Wang, H., Yan, L., Wang, X., Pei, R., Yan, T., Zhao, Y., & Guo, X. (2005) · Environmental Science & Technology · doi:10.1021/es048729l · Cited by 1,404 · see citing works

Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.

Zhang, S., Holmes, T. C., Lockshin, C., & Rich, A. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3334 · Cited by 1,304 · see citing works

Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials

Hartgerink, J. D., Beniash, E., & Stupp, S. I. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072699999 · Cited by 1,241 · see citing works

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

Singh, N., Manshian, B. B., Jenkins, G. J. S., Griffiths, S. M., Williams, P. M., Maffeïs, T. G. G., Wright, C. J., & Doak, S. H. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.04.009 · Cited by 1,190 · see citing works

Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds

Holmes, T. C., Lacalle, S. D., Su, X., Liu, G., Rich, A., & Zhang, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.12.6728 · Cited by 1,124 · see citing works

The biocompatibility of carbon nanotubes

Smart, S. K., Cassady, A. I., Lu, G. Q., & Martin, D. J. (2006) · Carbon · doi:10.1016/j.carbon.2005.10.011 · Cited by 1,011 · see citing works

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., MacGregor, L., Kiers, L., Cherny, R., Li, Q.-X., Tammer, A., et al. (2003) · Archives of Neurology · doi:10.1001/archneur.60.12.1685 · Cited by 988 · see citing works

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

Teng, Y. D., Lavik, E., Qu, X., Park, K. I., Ourednik, J., Zurakowski, D., Langer, R., & Snyder, E. Y. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052678899 · Cited by 967 · see citing works

Radical Reactions of C 60

Krusic, P. J., Wasserman, E., Keizer, P. N., Morton, J. R., & Preston, K. F. (1991) · Science · doi:10.1126/science.254.5035.1183 · Cited by 925 · see citing works

Oxidative damage in Alzheimer's

Smith, M. A., Perry, G. L., Richey, P. L., Sayrec, L. M., Anderson, V. E., Beal, M. F., & Kowall, N. W. (1996) · Nature · doi:10.1038/382120b0 · Cited by 897 · see citing works

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

Meyer‐Franke, A., Kaplan, M. R., Pfrieger, F. W., & Barres, B. A. (1995) · Neuron · doi:10.1016/0896-6273(95)90172-8 · Cited by 852 · see citing works

Nano neuro knitting: Peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision

Ellis-Behnke, R. G., Liang, Y., You, S., Tay, D., Zhang, S., So, K., & Schneider, G. E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600559103 · Cited by 796 · see citing works

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology

Abbott, N. J. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.006 · Cited by 786 · see citing works

Carboxyfullerenes as neuroprotective agents

Dugan, L. L., Turetsky, D. M., Du, C., Lobner, D., Wheeler, M. E., Almli, C. R., Shen, C. K.-F., Luh, T., Choi, D. W., & Lin, T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9434 · Cited by 747 · see citing works

Phase II Trial of Gefitinib in Recurrent Glioblastoma

Rich, J. N., Reardon, D. A., Peery, T., Dowell, J. M., Quinn, J. A., Penne, K. L., Wikstrand, C. J., Van Duyn, L. B., Dancey, J. E., McLendon, R. E., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.08.110 · Cited by 734 · see citing works

Self-Assembling Nanofibers Inhibit Glial Scar Formation and Promote Axon Elongation after Spinal Cord Injury

Tysseling, V. M., Sahni, V., Niece, K. L., Birch, D. V., Czeisler, C. M., Fehlings, M. G., Stupp, S. I., & Kessler, J. A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0143-08.2008 · Cited by 680 · see citing works

A Synthetic Peptide Containing the IKVAV Sequence from the A Chain of Laminin Mediates Cell Attachment, Migration, and Neurite Outgrowth

Tashiro, K., Sephel, G. C., Weeks, B. S., Sasaki, M., Martin, G. R., Kleinman, H. K., & Yamada, Y. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71604-9 · Cited by 643 · see citing works

Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering

Yang, F., Ramalingam, M., Ramakrishna, S., Wang, X., Ma, Y.-X., & Wang, S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.08.062 · Cited by 604 · see citing works

A Controlled Trial of Rasagiline in Early Parkinson Disease

Parkinson Study Group (2002) · Archives of Neurology · doi:10.1001/archneur.59.12.1937 · Cited by 579 · see citing works

Single-Walled Carbon Nanotube Induces Oxidative Stress and Activates Nuclear Transcription Factor-κB in Human Keratinocytes

Manna, S. K., Sarkar, S., Barr, J., Wise, K., Barrera, E. V., Jejelowo, O., Rice-Ficht, A. C., & Ramesh, G. T. (2005) · Nano Letters · doi:10.1021/nl0507966 · Cited by 577 · see citing works

Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery

Guo, J., Gao, X., Su, L., Xia, H., Gu, G., Pang, Z., Jiang, X., Yao, L., Chen, J., & Chen, H. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.07.004 · Cited by 567 · see citing works

Involvement of the low‐density lipoprotein receptor‐related protein in the transcytosis of the brain delivery vector Angiopep‐2

Demeule, M., Currie, J., Bertrand, Y., Ché, C., Nguyen, T., Régina, A., Gabathuler, R., Castaigne, J., & Béliveau, R. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05492.x · Cited by 557 · see citing works

Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation

Kunzmann, A., Andersson, B., Buerki‐Thurnherr, T., Krug, H. F., Scheynius, A., & Fadeel, B. (2010) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2010.04.007 · Cited by 525 · see citing works

Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts

Cellot, G., Cilia, E., Cipollone, S., Rančić, V., Sucapane, A., Giordani, S., Gambazzi, L., Markram, H., Grandolfo, M., Scaini, D., et al. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.374 · Cited by 523 · see citing works

Oxidative mechanisms in nigral cell death in Parkinson's disease.

Jenner, P. G. (1998) · PubMed · doi:10.1002/mds.870131304 · Cited by 511 · see citing works

A Global Perspective on Spinal Cord Injury Epidemiology

Ackery, A., Tator, C. H., & Krassioukov, A. V. (2004) · Journal of Neurotrauma · doi:10.1089/neu.2004.21.1355 · Cited by 487 · see citing works

Neuronal Intrinsic Mechanisms of Axon Regeneration

Liu, K., Tedeschi, A., Park, K. K., & He, Z. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113723 · Cited by 458 · see citing works

In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells

Davoren, M., Herzog, E., Casey, A., Cottineau, B., Chambers, G., Byrne, H. J., & Lyng, F. M. (2006) · Toxicology in Vitro · doi:10.1016/j.tiv.2006.10.007 · Cited by 440 · see citing works

EGFRvIII Antibody–Conjugated Iron Oxide Nanoparticles for Magnetic Resonance Imaging–Guided Convection-Enhanced Delivery and Targeted Therapy of Glioblastoma

Hadjipanayis, C. G., Machaidze, R., Kaluzová, M., Wang, L., Schuette, A. J., Chen, H., Wu, X., & Mao, H. Z. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-1022 · Cited by 420 · see citing works

Repairing the Injured Spinal Cord

Schwab, M. E. (2002) · Science · doi:10.1126/science.1067840 · Cited by 403 · see citing works

Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons

Lotharius, J., Dugan, L. L., & O’Malley, K. L. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-04-01284.1999 · Cited by 403 · see citing works

Angiopep-conjugated poly(ethylene glycol)-co-poly(ε-caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma

Xin, H., Jiang, X., Gu, J., Sha, X., Chen, L., Law, K., Chen, Y., Wang, X., Jiang, Y., & Fang, X. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.02.044 · Cited by 384 · see citing works

Buckminsterfullerenol Free Radical Scavengers Reduce Excitotoxic and Apoptotic Death of Cultured Cortical Neurons

Dugan, L. L., Gabrielsen, J. K., Yu, S. P., Lin, T., & Choi, D. W. (1996) · Neurobiology of Disease · doi:10.1006/nbdi.1996.0013 · Cited by 384 · see citing works

Epidermal Growth Factor Receptor–Targeted Immunoliposomes Significantly Enhance the Efficacy of Multiple Anticancer DrugsIn vivo

Mamot, C., Drummond, D. C., Noble, C. O., Kallab, V., Guo, Z., Hong, K., Kirpotin, D. B., & Park, J. W. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1093 · Cited by 383 · see citing works

Nanogels for Oligonucleotide Delivery to the Brain

Vinogradov, S. V., Batrakova, E. V., & Kabanov, A. V. (2003) · Bioconjugate Chemistry · doi:10.1021/bc034164r · Cited by 379 · see citing works

Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues

Földvári, M., & Bagonluri, M. (2008) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2008.04.003 · Cited by 379 · see citing works

Axonal Regeneration and Functional Recovery after Complete Spinal Cord Transection in Rats by Delayed Treatment with Transplants and Neurotrophins

Coumans, J. V., Lin, T. T.-S., Dai, H., MacArthur, L. H., McAtee, M., Nash, C., & Bregman, B. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-23-09334.2001 · Cited by 371 · see citing works

Cholinergic nucleus basalis tauopathy emerges early in the aging‐MCI‐AD continuum

Mesulam, M. M., Shaw, P. L., Mash, D. C., & Weıntraub, S. (2004) · Annals of Neurology · doi:10.1002/ana.20100 · Cited by 365 · see citing works

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

Wilson, B., Samanta, M. K., Santhi, K., Kumar, K. P. S., Paramakrishnan, N., & Suresh, B. (2008) · Brain Research · doi:10.1016/j.brainres.2008.01.039 · Cited by 363 · see citing works

EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans

Koprivica, V., Cho, K., Park, J. B., Yiu, G. C., Atwal, J. K., Gore, B. B., Kim, J. A., Lin, E., Tessier‐Lavigne, M., Chen, D. F., et al. (2005) · Science · doi:10.1126/science.1115462 · Cited by 363 · see citing works

Nanomedicines and nanotoxicology: some physiological principles

Garnett, M. C., & Kallinteri, P. (2006) · Occupational Medicine · doi:10.1093/occmed/kql052 · Cited by 352 · see citing works

Interfacing Neurons with Carbon Nanotubes: Electrical Signal Transfer and Synaptic Stimulation in Cultured Brain Circuits

Mazzatenta, A., Giugliano, M., Campidelli, S., Gambazzi, L., Businaro, L., Markram, H., Prato, M., & Ballerini, L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1051-07.2007 · Cited by 348 · see citing works

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Agemy, L., Friedmann‐Morvinski, D., Kotamraju, V. R., Roth, L., Sugahara, K. N., Girard, O. M., Mattrey, R. F., Verma, I. M., & Ruoslahti, E. I. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114518108 · Cited by 348 · see citing works

Diagnosis and Initial Management of Parkinson's Disease

Nutt, J. G., & Wooten, G. F. (2005) · New England Journal of Medicine · doi:10.1056/nejmcp043908 · Cited by 337 · see citing works

Clinical toxicities of nanocarrier systems.

Vega-Villa, K. R., Takemoto, J. K., Yáñez, J. A., Remsberg, C. M., Forrest, M. L., & Davies, N. M. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.11.007 · Cited by 325 · see citing works

Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating alzheimer disease.

Yang, Z., Zhang, Y., Yang, Y., Sun, L., Han, D., Li, H., & Wang, C. (2010) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2009.11.007 · Cited by 311 · see citing works

PEGylated Poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors

He, H., Li, Y., Jia, X., Du, J., Ying, X., Lü, W.-L., Lou, J., & Wei, Y. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.09.002 · Cited by 303 · see citing works

Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells

Mamot, C., Drummond, D. C., Greiser, U., Hong, K., Kirpotin, D. B., Marks, J. D., & Park, J. W. (2004) · The Women s Oncology Review · doi:10.3109/14733400410001727592 · Cited by 298 · see citing works

Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues

Brambilla, D., Droumaguet, B. L., Nicolas, J., Hashemi, S. H., Wu, L., Moghimi, S. M., Couvreur, P., & Andrieux, K. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.03.008 · Cited by 293 · see citing works

Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles

Gao, K., & Jiang, X. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.11.040 · Cited by 269 · see citing works

Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury

Hawryluk, G. W. J., Rowland, J. W., Kwon, B. K., & Fehlings, M. G. (2008) · Neurosurgical FOCUS · doi:10.3171/foc.2008.25.11.e14 · Cited by 252 · see citing works

Methotrexate Loaded Polyether-Copolyester Dendrimers for the Treatment of Gliomas: Enhanced Efficacy and Intratumoral Transport Capability

Dhanikula, R. S., Argaw, A., Bouchard, J., & Hildgen, P. (2008) · Molecular Pharmaceutics · doi:10.1021/mp700086j · Cited by 246 · see citing works

Stem cell therapies for spinal cord injury

Sahni, V., & Kessler, J. A. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.73 · Cited by 246 · see citing works

Rivastigmine-loaded PLGA and PBCA nanoparticles: Preparation, optimization, characterization, in vitro and pharmacodynamic studies

Joshi, S. A., Chavhan, S. S., & Sawant, K. K. (2010) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2010.07.007 · Cited by 235 · see citing works

Reknitting the injured spinal cord by self-assembling peptide nanofiber scaffold

Guo, J., Su, H., Zeng, Y., Liang, Y.-X., Wong, W. M., Ellis-Behnke, R. G., So, K., & Wu, W. (2007) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2007.09.003 · Cited by 234 · see citing works

Nanoparticles: molecular targets and cell signalling

Marano, F., Hussain, S., Rodrigues‐Lima, F., Baeza‐Squiban, A., & Boland, S. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0546-4 · Cited by 232 · see citing works

Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide

Mourtas, S., Canovi, M., Zona, C., Aurilia, D., Niarakis, A., Ferla, B. L., Salmona, M., Nicotra, F., Gobbi, M., & Antimisiaris, S. G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.10.027 · Cited by 231 · see citing works

Surface Expressed Nucleolin Is Constantly Induced in Tumor Cells to Mediate Calcium-Dependent Ligand Internalization

Hovanessian, A. G., Soundaramourty, C., Khoury, D. E., Nondier, I., Svab, J., & Krust, B. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015787 · Cited by 219 · see citing works

Cationic Albumin–Conjugated Pegylated Nanoparticles Allow Gene Delivery into Brain Tumors via Intravenous Administration

Lü, W., Sun, Q. Q., Wan, J., She, Z., & Jiang, X. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-2354 · Cited by 219 · see citing works

Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels

Burdick, J. A., Ward, M. S., Liang, E. T., Young, M. J., & Langer, R. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.06.034 · Cited by 216 · see citing works

Novel -penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases

Cui, Z., Lockman, P. R., Atwood, C., Hsu, C. C., Gupte, A., ALLEN, D., & Mumper, R. J. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.07.009 · Cited by 203 · see citing works

Epidermal Growth Factor Receptor Activation: An Upstream Signal for Transition of Quiescent Astrocytes into Reactive Astrocytes after Neural Injury

Liu, B., Chen, H., Johns, T. G., & Neufeld, A. H. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1004-06.2006 · Cited by 202 · see citing works

An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury

Piantino, J. A., Burdick, J. A., GOLDBERG, D., Langer, R., & Benowitz, L. I. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.04.020 · Cited by 201 · see citing works

Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel™)

Woerly, S. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00354-9 · Cited by 199 · see citing works

A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats

Garcion, E., Lamprecht, A., Heurtault, B., Paillard, A., Aubert‐Pouëssel, A., Denizot, B., Meneï, P., & Benoît, J. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0289 · Cited by 198 · see citing works

Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism.

Zhang, Y., Calon, F., Zhu, C., Boado, R. J., & Pardridge, W. M. (2003) · Human Gene Therapy · doi:10.1089/10430340360464660 · Cited by 194 · see citing works

Brain trace elements in Alzheimer's disease.

Ehmann, W. D., Markesbery, W. R., Alauddin, M., Hossain, T. I., & Brubaker, E. H. (1986) · PubMed · Cited by 192 · see citing works

Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles

Lin, X., Tian, Wei, Feng, Huang, Wang, Ren, R., & Diao (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s16570 · Cited by 189 · see citing works

Protein refolding assisted by self‐assembled nanogels as novel artificial molecular chaperone

Nomura, Y., Ikeda, M., Yamaguchi, N., Aoyama, Y., & Akiyoshi, K. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01028-7 · Cited by 186 · see citing works

Translocation of Poly(ethylene glycol-co-hexadecyl)cyanoacrylate Nanoparticles into Rat Brain Endothelial Cells: Role of Apolipoproteins in Receptor-Mediated Endocytosis

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Alzheimer’s Disease and Parkinson’s Disease: A Review of Current Treatment Adopting a Nanotechnology Approach

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Nanoparticle-Based Strategies to Treat Neuro-Inflammation

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Diagnostic and Therapeutic Uses of Nanomaterials in the Brain

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Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles

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Development of a hybrid nanocarrier-recognizing tumor vasculature and penetrating the BBB for glioblastoma multi-targeting therapy

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The application of multifunctional nanomaterials in Alzheimer’s disease: A potential theranostics strategy

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Building sustainable neuroscience capacity in Africa: the role of non-profit organisations

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Preparation and optimization of rivastigmine-loaded tocopherol succinate-based solid lipid nanoparticles

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Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging

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Europium-Doped Cerium Oxide Nanoparticles for Microglial Amyloid Beta Clearance and Homeostasis

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Strategies and materials of "SMART" non-viral vectors: Overcoming the barriers for brain gene therapy

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Diagnosis of prostate cancer via nanotechnological approach

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Emerging role of nanomedicine in the treatment of neuropathic pain

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Recent advancements in nanoparticle-mediated approaches for restoration of multiple sclerosis

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Nanomedicine applications in women's health: state of the art

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Protein Nanotubes as Advanced Material Platforms and Delivery Systems

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Anchoring effects of surface chemistry on gold nanorods: modulating autophagy

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Recent advances of nanomaterials for intervention in Parkinson’s disease in the context of anti-inflammation

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Ultrasound-activated nano-TiO2 loaded with temozolomide paves the way for resection of chemoresistant glioblastoma multiforme

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Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules)

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Advances in Alzheimer's therapy: Exploring neuropathological mechanisms to revolutionize the future therapeutic landscape

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Role of Nanoparticles and Nanomaterials in Drug Delivery: An Overview

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Pathogen-inspired drug delivery to the central nervous system

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Cytotoxicity Study on Luminescent Nanocrystals Containing Phospholipid Micelles in Primary Cultures of Rat Astrocytes

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Where do we stand now regarding treatment of psychiatric and neurodegenerative disorders? Considerations in using magnetoelectric nanoparticles as an innovative approach

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Diagnostics and theranostics of central nervous system diseases based on aggregation-induced emission luminogens

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Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging

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Multiwalled Carbon Nanotubes Induced Hypotension by Regulating the Central Nervous System

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The Dynamic Interactions between Nanoparticles and Macrophages Impact Their Fate in Brain Tumors

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Therapeutic Potential of Natural Product-Based Oral Nanomedicines for Stroke Prevention

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The potential of graphene coatings as neural interfaces

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Pharmacological agents and transport nanosystems based on plant phospholipids

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Designing Novel Nanoformulations Targeting Glutamate Transporter Excitatory Amino Acid Transporter 2: Implications in Treating Drug Addiction.

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Non-viral vectors based on magnetoplexes, lipoplexes and polyplexes for VEGF gene delivery into central nervous system cells

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NANOPARTICLE-BASED DRUG DELIVERY FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

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Nanoengineering and nanotechnology for diagnosis and treatment of CNS and neurological diseases

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Cell type-targeting nanoparticles in treating central nervous system diseases: Challenges and hopes

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