Depression—an underrecognized target for prevention of dementia in Alzheimer’s disease

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395 · see citing works

Neuroinflammation in Alzheimer's disease

Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226 · see citing works

Dementia prevention, intervention, and care

Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31363-6 · Cited by 6,072 · see citing works

The global prevalence of dementia: a systematic review and metaanalysis.

Prince, M., Bryce, R., Albanese, E., Wimo, A., Ribeiro, W., & Ferri, C. P. (2013) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2012.11.007 · Cited by 4,941 · see citing works

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C., & Trojanowski, J. Q. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70299-6 · Cited by 4,806 · see citing works

A Meta-Analysis of Cytokines in Major Depression

Dowlati, Y., Herrmann, N., Swardfager, W., Liu, H., Sham, L., Reim, E. K., & Lanctôt, K. L. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.033 · Cited by 4,729 · see citing works

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321 · see citing works

The role of inflammation in depression: from evolutionary imperative to modern treatment target

Miller, A. H., & Raison, C. L. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2015.5 · Cited by 3,942 · see citing works

A Neurotrophic Model for Stress-Related Mood Disorders

Duman, R. S., & Monteggia, L. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.013 · Cited by 3,375 · see citing works

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

Malberg, J. E., Eisch, A. J., Nestler, E. J., & Duman, R. S. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-24-09104.2000 · Cited by 3,111 · see citing works

Cytokines sing the blues: inflammation and the pathogenesis of depression

Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009 · see citing works

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis

Sapolsky, R. M., Krey, L. C., & McEwen, B. S. (1986) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2002.38.cp21 · Cited by 2,287 · see citing works

World Alzheimer Report 2015 - The Global Impact of Dementia:An analysis of prevalence, incidence, cost and trends

(2015) · HAL · Cited by 2,238 · see citing works

'Vascular Depression' Hypothesis

Alexopoulos, G. S. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830220033006 · Cited by 1,843 · see citing works

Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia: A Meta-analysis

Jansen, W. J., Ossenkoppele, R., Knol, D. L., Tijms, B. M., Scheltens, P., Verhey, F. R. J., Visser, P. J., Aalten, P., Aarsland, D., Alcolea, D., et al. (2015) · JAMA · doi:10.1001/jama.2015.4668 · Cited by 1,610 · see citing works

Depression and Risk for Alzheimer Disease: Systematic Review, Meta-analysis, and Metaregression Analysis

Ownby, R. L., Crocco, E., Acevedo, A., John, V., & Loewenstein, D. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.5.530 · Cited by 1,493 · see citing works

Twenty years of research on cytokine-induced sickness behavior

Dantzer, R., & Kelley, K. W. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.09.006 · Cited by 1,420 · see citing works

Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies

Diniz, B. S., Butters, M. A., Albert, S. M., Dew, M. A., & Reynolds, C. F. (2013) · British Journal of Psychiatry · doi:10.1192/bjp.bp.112.118307 · Cited by 1,290 · see citing works

Depression and risk of developing dementia

Byers, A. L., & Yaffe, K. (2011) · Nature Reviews Neurology · doi:10.1038/nrneurol.2011.60 · Cited by 1,265 · see citing works

Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications

Felger, J. C., & Lotrich, F. E. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.04.060 · Cited by 1,180 · see citing works

Untreated Depression and Hippocampal Volume Loss

Sheline, Y. I., Gado, M. H., & Kraemer, H. C. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.8.1516 · Cited by 1,180 · see citing works

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

ARUK Consortium, Sims, R., GERAD/PERADES, C., van der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., et al. (2017) · Nature Genetics · doi:10.1038/ng.3916 · Cited by 1,126 · see citing works

A Meta-Analysis of Cytokines in Alzheimer's Disease

Swardfager, W., Lanctôt, K., Rothenburg, L., Wong, A., Cappell, J., & Herrmann, N. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.012 · Cited by 1,108 · see citing works

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

Czéh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomucci, A., & Fuchs, E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211427898 · Cited by 1,090 · see citing works

BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

Mattson, M. P., Maudsley, S., & Martin, B. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.08.001 · Cited by 942 · see citing works

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

Setiawan, E., Wilson, A. A., Mizrahi, R., Rusjan, P. M., Miler, L., Rajkowska, G., Suridjan, I., Kennedy, J. L., Rekkas, P. V., Houle, S., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.2427 · Cited by 939 · see citing works

Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment

Malberg, J. E., & Duman, R. S. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300234 · Cited by 815 · see citing works

Hippocampal Neurogenesis: Regulation by Stress and Antidepressants

Dranovsky, A., & Hen, R. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.082 · Cited by 663 · see citing works

Glucocorticoids increase amyloid-β and tau pathology in a mouse model of alzheimer’s disease

Green, K. N., Billings, L. M., Roozendaal, B., McGaugh, J. L., & LaFerla, F. M. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.2797-06.2006 · Cited by 623 · see citing works

Depression: a case of neuronal life and death?

Duman, R. S. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.02.033 · Cited by 612 · see citing works

Preclinical models: status of basic research in depression

Nestler, E. J., Gould, E., & Manji, H. K. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01405-1 · Cited by 559 · see citing works

How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans

Frodl, T., & O'Keane, V. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.03.012 · Cited by 555 · see citing works

Depression as a Risk Factor for Alzheimer Disease: The MIRAGE Study

Green, R. C., Cupples, L. A., Kurz, A., Auerbach, S., Go, R., Sadovnick, D., Duara, R., Kukull, W. A., Chui, H., Edeki, T., et al. (2003) · Archives of Neurology · doi:10.1001/archneur.60.5.753 · Cited by 551 · see citing works

Pathways linking late-life depression to persistent cognitive impairment and dementia

Butters, M. A., Young, J. K., López, O. L., Aizenstein, H. J., Mulsant, B. H., Reynolds, C. F., DeKosky, S. T., & Becker, J. T. (2008) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2008.10.3/mabutters · Cited by 538 · see citing works

Prevalence of Depression in Patients With Mild Cognitive Impairment: A Systematic Review and Meta-analysis

Ismail, Z., Elbayoumi, H., Fischer, C. E., Hogan, D. B., Millikin, C. P., Schweizer, T., Mortby, M. E., Smith, E. E., Patten, S. B., & Fiest, K. M. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3162 · Cited by 532 · see citing works

Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study

Singh-Manoux, A., Dugravot, A., Fournier, A., Abell, J., Ebmeier, K., Kivimäki, M., & Sabia, S. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0660 · Cited by 529 · see citing works

History of Depression as a Risk Factor for Dementia: An Updated Review

Jorm, A. F. (2001) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2001.00967.x · Cited by 526 · see citing works

Depressive Symptoms, Vascular Disease, and Mild Cognitive Impairment: Findings From the Cardiovascular Health Study

Barnes, D. E., Alexopoulos, G. S., Lopez, O. L., Williamson, J. D., & Yaffe, K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.3.273 · Cited by 465 · see citing works

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

Felger, J. C., & Treadway, M. T. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.143 · Cited by 453 · see citing works

Midlife vs Late-Life Depressive Symptoms and Risk of Dementia

Yaffe, K. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1481 · Cited by 449 · see citing works

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice

Mainardi, M., Garbo, A. D., Caleo, M., Berardi, N., Sale, A., & Maffei, L. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00001 · Cited by 438 · see citing works

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

Anacker, C., Zunszain, P. A., Cattaneo, A., Carvalho, L. A., Garabedian, M. J., Thuret, S., Price, J., & Pariante, C. M. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.26 · Cited by 435 · see citing works

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer’s Disease

Fagan, A. M., Xiong, C., Jasielec, M. S., Bateman, R. J., Goate, A. M., Benzinger, T. L. S., Ghetti, B., Martins, R. N., Masters, C. L., Mayeux, R., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3007901 · Cited by 434 · see citing works

Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder?

Kessing, L. V. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2003.031773 · Cited by 406 · see citing works

Treating Depression in Alzheimer Disease: Efficacy and Safety of Sertraline Therapy, and the Benefits of Depression Reduction: The DIADS

Lyketsos, C. G., DelCampo, L., Steinberg, M., Miles, Q., Steele, C. D., Munro, C., Baker, A. S., Sheppard, J.-M. E., Frangakis, C., Brandt, J., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.7.737 · Cited by 398 · see citing works

Late-life depression, mild cognitive impairment, and dementia

Richard, E., Reitz, C., Honig, L. H., Schupf, N., Tang, M. X., Manly, J. J., Mayeux, R., Devanand, D., & Luchsinger, J. A. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.603 · Cited by 389 · see citing works

Recurrent depressive symptoms and the incidence of dementia and mild cognitive impairment

Dotson, V. M., Beydoun, M. A., & Zonderman, A. B. (2010) · Neurology · doi:10.1212/wnl.0b013e3181e62124 · Cited by 385 · see citing works

A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia

Tynan, R. J., Weidenhofer, J., Hinwood, M., Cairns, M. J., Day, T. A., & Walker, F. R. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.12.011 · Cited by 382 · see citing works

Weight Loss and Malnutrition in Patients with Parkinson's Disease: Current Knowledge and Future Prospects

Ma, K., Xiong, N., Shen, Y., Han, C., Liu, L., Zhang, G., Wang, L., Guo, S., Guo, X., Xia, Y. F., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00001 · Cited by 379 · see citing works

Hippocampal volume in geriatric depression

Steffens, D. C., Byrum, C. E., McQuoid, D. R., Greenberg, D. L., Payne, M. E., Blitchington, T. F., MacFall, J. R., & Krishnan, K. R. R. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00829-5 · Cited by 375 · see citing works

10-year trajectories of depressive symptoms and risk of dementia: a population-based study

Mirza, S. S., Wolters, F. J., Swanson, S. A., Koudstaal, P. J., Albert Hofman, D., Tiemeier, H. W., & Ikram, M. A. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)00097-3 · Cited by 371 · see citing works

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

Cirrito, J. R., Disabato, B. M., Restivo, J. L., Verges, D. K., Goebel, W. D., Sathyan, A., Hayreh, D., D'Angelo, G., Benzinger, T., Yoon, H., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107411108 · Cited by 370 · see citing works

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress

Magariños, A. M., Deslandes, A., & McEwen, B. S. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00163-6 · Cited by 330 · see citing works

The Temporal Relationship Between Depressive Symptoms and Dementia

Chen, P., Ganguli, M., Mulsant, B. H., & DeKosky, S. T. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.3.261 · Cited by 318 · see citing works

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

Lewczuk, P., Riederer, P. F., O’Bryant, S. E., Verbeek, M. M., Dubois, B., Visser, P. J., Jellinger, K. A., Engelborghs, S., Ramı́rez, A., Parnetti, L., et al. (2017) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2017.1375556 · Cited by 308 · see citing works

Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia

Kaup, A. R., Byers, A. L., Falvey, C., Simonsick, E. M., Satterfield, S., Ayonayon, H. N., Smagula, S. F., Rubin, S. M., & Yaffe, K. S. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.0004 · Cited by 291 · see citing works

Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults

Donovan, N. J., Locascio, J. J., Marshall, G. A., Gatchel, J., Hanseeuw, B. J., Rentz, D. M., Johnson, K. A., Sperling, R. A., & Study, F. T. H. A. B. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17040442 · Cited by 272 · see citing works

Serotonin and Human Cognitive Performance

Schmitt, J. A. J., Wingen, M., Ramaekers, J. G., Evers, E. A. T., & Riedel, W. J. (2006) · Current Pharmaceutical Design · doi:10.2174/138161206777698909 · Cited by 258 · see citing works

Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study

Setiawan, E., Attwells, S., Wilson, A. A., Mizrahi, R., Rusjan, P., Miler, L., Xu, C., Sharma, S. K., Kish, S. J., Houle, S., et al. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30048-8 · Cited by 245 · see citing works

Inflammatory markers and the risk of dementia and Alzheimer's disease: a meta-analysis

Darweesh, S. K. L., Wolters, F. J., Ikram, M. A., de Wolf, F., Bos, D., & Hofman, A. (2018) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2018.02.014 · Cited by 244 · see citing works

Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults

Sprecher, K. E., Bendlin, B. B., Racine, A. M., Okonkwo, O. C., Christian, B. T., Koscik, R. L., Sager, M. A., Asthana, S., Johnson, S. C., & Benca, R. M. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.05.004 · Cited by 243 · see citing works

An Antidepressant Decreases CSF Aβ Production in Healthy Individuals and in Transgenic AD Mice

Sheline, Y., West, T., Yarasheski, K., Swarm, R., Jasielec, M. S., Fisher, J. R., Ficker, W. D., Yan, P., Xiong, C., Frederiksen, C., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008169 · Cited by 238 · see citing works

Stress and the Aging Hippocampus

McEwen, B. S. (1999) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1998.0173 · Cited by 231 · see citing works

Depression, Apolipoprotein E Genotype, and the Incidence of Mild Cognitive Impairment: A Prospective Cohort Study

Geda, Y. E., Knopman, D. S., Mrazek, D. A., Jicha, G. A., Smith, G. E., Negash, S., Boeve, B. F., Ivnik, R. J., Petersen, R. C., Pankratz, V. S., et al. (2006) · Archives of Neurology · doi:10.1001/archneur.63.3.435 · Cited by 230 · see citing works

Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults

Sprecher, K. E., Koscik, R. L., Carlsson, C. M., Zetterberg, H., Blennow, K., Okonkwo, O. C., Sager, M. A., Asthana, S., Johnson, S. C., Benca, R. M., et al. (2017) · Neurology · doi:10.1212/wnl.0000000000004171 · Cited by 221 · see citing works

Depression as a modifiable factor to decrease the risk of dementia

Almeida, O. P., Hankey, G. J., Yeap, B. B., Golledge, J., & Flicker, L. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.90 · Cited by 212 · see citing works

Cerebrospinal fluid and plasma free cortisol concentrations in depression

Carroll, B. J., Curtis, G. C., & MENDELS, J. (1976) · Psychological Medicine · doi:10.1017/s0033291700013775 · Cited by 207 · see citing works

Association of Excessive Daytime Sleepiness With Longitudinal β-Amyloid Accumulation in Elderly Persons Without Dementia

Carvalho, D. Z., Louis, E. K. S., Knopman, D. S., Boeve, B. F., Lowe, V. J., Roberts, R. O., Mielke, M. M., Przybelski, S. A., Machulda, M. M., Petersen, R. C., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.0049 · Cited by 207 · see citing works

Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer’s Dementia in Individuals With Previous Depression

Bartels, C., Wagner, M., Wolfsgruber, S., Ehrenreich, H., Schneider, A., & Initiative, F. T. A. D. N. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17040404 · Cited by 202 · see citing works

Cell atrophy and loss in depression: reversal by antidepressant treatment

Banasr, M., Dwyer, J. M., & Duman, R. S. (2011) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2011.09.002 · Cited by 201 · see citing works

A new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice

Brustolim, D., Ribeiro‐dos‐Santos, R., Kast, R. E., Altschuler, E. L., & Soares, M. B. P. (2006) · International Immunopharmacology · doi:10.1016/j.intimp.2005.12.007 · Cited by 195 · see citing works

Late-Life Depression as a Risk Factor for Mild Cognitive Impairment or Alzheimer's Disease in 30 US Alzheimer's Disease Centers

Steenland, K., Karnes, C., Seals, R. M., Carnevale, C. V., Hermida, A. P., & Levey, A. I. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-111922 · Cited by 188 · see citing works

A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

Walker, F. R. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.10.002 · Cited by 175 · see citing works

Clinical risk factors for Alzheimer's disease

Kokmen, E., Beard, C. M., Chandra, V., OFFORD, K. P., Schoenberg, B. S., & Ballard, D. (1991) · Neurology · doi:10.1212/wnl.41.9.1393 · Cited by 170 · see citing works

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type

Popp, J., Wolfsgruber, S., Heuser, I., Peters, O., Hüll, M., Schröder, J., Möller, H., Lewczuk, P., Schneider, A., Jahn, H., et al. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.10.031 · Cited by 170 · see citing works

Depressive Symptoms and Incidence of Mild Cognitive Impairment and Probable Dementia in Elderly Women: The Women's Health Initiative Memory Study

Goveas, J. S., Espeland, M. A., Woods, N. F., Wassertheil-Smoller, S. W., & Kotchen, J. M. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03233.x · Cited by 154 · see citing works

Long-term cortisol measures predict Alzheimer disease risk

Ennis, G. E., An, Y., Resnick, S. M., Ferrucci, L., O'Brien, R. J., & Moffat, S. D. (2017) · Neurology · doi:10.1212/wnl.0000000000003537 · Cited by 151 · see citing works

Does Fluoxetine Have Any Effect on the Cognition of Patients With Mild Cognitive Impairment?

Mowla, A., Mosavinasab, M., & Pani, A. (2007) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31802e0002 · Cited by 141 · see citing works

Major depression, cognitive dysfunction and Alzheimer's disease: Is there a link?

Sierksma, A. S. R., van den Hove, D. L. A., Steinbusch, H. W. M., & Prickaerts, J. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.10.021 · Cited by 139 · see citing works

Inflammation-induced depression: Its pathophysiology and therapeutic implications

Jeon, S. W., & Kim, Y.-K. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.10.016 · Cited by 134 · see citing works

Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults

Gatchel, J. R., Rabin, J. S., Buckley, R. F., Locascio, J. J., Quiroz, Y. T., Yang, H., Vannini, P., Amariglio, R. E., Rentz, D. M., Properzi, M. J., et al. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.8964 · Cited by 131 · see citing works

Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study

Gatchel, J. R., Donovan, N. J., Locascio, J. J., Schultz, A. P., Becker, J. A., Chhatwal, J. P., Papp, K. V., Amariglio, R. E., Rentz, D. M., Blacker, D., et al. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170001 · Cited by 125 · see citing works

Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression

Gallagher, D., Kiss, A., Lanctot, K., & Herrmann, N. (2018) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2018.05.002 · Cited by 122 · see citing works

Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus

Alfonso, J., Pollevick, G. D., Hart, M. G. V. D., Flügge, G., Fuchs, E., & Frasch, A. C. C. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03178.x · Cited by 117 · see citing works

Longitudinal Association of Dementia and Depression

Snowden, M. B., Atkins, D. C., Steinman, L. E., Bell, J. F., Bryant, L. L., Copeland, C., & Fitzpatrick, A. L. (2014) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2014.09.002 · Cited by 117 · see citing works

The Prevalence of Depression in Alzheimer’s Disease: A Systematic Review and Meta-Analysis

Chi, S., Wang, C., Jiang, T., Zhu, X., Yu, J., & Tan, L. (2015) · Current Alzheimer Research · doi:10.2174/1567205012666150204124310 · Cited by 115 · see citing works

Antidepressants and dementia

Kessing, L. V., Søndergård, L., Forman, J. L., & Andersen, P. K. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.11.020 · Cited by 113 · see citing works

Cortisol, cytokines, and hippocampal volume interactions in the elderly

Sudheimer, K. D., O'Hara, R. M., Spiegel, D., Powers, B. N., KRAEMER, H. C., Neri, E., Weiner, M. W., Hardan, A. Y., Hallmayer, J. F., & Dhabhar, F. S. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00153 · Cited by 111 · see citing works

Genetics of Alzheimer disease in the pre- and post-GWAS era

Ertekin‐Taner, N. (2010) · Alzheimer s Research & Therapy · doi:10.1186/alzrt26 · Cited by 107 · see citing works

The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?

Hermida, A. P., McDonald, W. M., Steenland, K., & Levey, A. I. (2012) · Expert Review of Neurotherapeutics · doi:10.1586/ern.12.127 · Cited by 100 · see citing works

Depressive symptoms accelerate cognitive decline in amyloid-positive MCI patients

Initiative, F. T. A. D. N., Brendel, M., Pogarell, O., Xiong, G., Delker, A., Bartenstein, P., & Rominger, A. (2015) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-014-2975-4 · Cited by 94 · see citing works

Methodology and Preliminary Results From the Neurocognitive Outcomes of Depression in the Elderly Study

Steffens, D. C., Welsh-Bohmer, K. A., Burke, J. R., Plassman, B. L., Beyer, J. L., Gersing, K. R., & Potter, G. G. (2004) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988704269819 · Cited by 90 · see citing works

Neuropsychiatric Symptoms in Amnestic and Nonamnestic Mild Cognitive Impairment

Rozzini, L., Chilovi, B. V., Conti, M. Z., Delrio, I., Borroni, B., Trabucchi, M., & Padovani, A. (2007) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000111133 · Cited by 86 · see citing works

CSF cortisol in Alzheimer's disease and mild cognitive impairment

Popp, J., Schaper, K., Kölsch, H., Cvetanovska, G., Rommel, F., Klingmüller, D., Dodel, R. C., Wüllner, U., & Jessen, F. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.07.007 · Cited by 83 · see citing works

Late-Life Depression and the Prodromes of Dementia

Steffens, D. C. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0658 · Cited by 82 · see citing works

No Association of Lower Hippocampal Volume With Alzheimer’s Disease Pathology in Late-Life Depression

De Winter, F.-L., Emsell, L., Bouckaert, F., Claes, L., Jain, S., Farrar, G., Billiet, T., Evers, S., Van den Stock, J., Sienaert, P., et al. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16030319 · Cited by 80 · see citing works

Venlafaxine exhibits an anti-inflammatory effect in an inflammatory co-culture model

Vollmar, P., Haghikia, A., Dermietzel, R., & Faustmann, P. M. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007729 · Cited by 75 · see citing works

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease

Kajiwara, Y., Franciosi, S., Takahashi, N., Krug, L., Schmeidler, J., Taddei, K., Haroutunian, V. H., Fried, U., Ehrlich, M. E., Martins, R. N., et al. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-1 · Cited by 73 · see citing works

Do continued antidepressants protect against dementia in patients with severe depressive disorder?

Kessing, L., Forman, J., & Andersen, P. (2011) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32834ace0f · Cited by 71 · see citing works

Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease

Aboukhatwa, M. A., Dosanjh, L. E., & Luo, Y. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-10 · Cited by 69 · see citing works

Comparison of Sertraline, Venlafaxine and Desipramine Effects on Depression, Cognition and the Daily Living Activities in Alzheimer Patients

Mokhber, N., Abdollahian, E., Soltanifar, A., Samadi, R., Saghebi, A., Haghighi, M., & Azarpazhooh, A. (2014) · Pharmacopsychiatry · doi:10.1055/s-0034-1377041 · Cited by 61 · see citing works

Chronic sleep fragmentation exacerbates amyloid β deposition in Alzheimer’s disease model mice

Minakawa, E. N., Miyazaki, K., Maruo, K., Yagihara, H., Fujita, H., Wada, K., & Nagai, Y. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.05.054 · Cited by 59 · see citing works

The Role of Fluoxetine in Activating Wnt/β-Catenin Signaling and Repressing β-Amyloid Production in an Alzheimer Mouse Model

Huang, M., Liang, Y., Chen, H., Xu, B., Chai, C., & Xing, P. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00164 · Cited by 59 · see citing works

Differential and Converging Molecular Mechanisms of Antidepressants’ Action in the Hippocampal Dentate Gyrus

Patrício, P., Mateus-Pinheiro, A., Irmler, M., Alves, N. D., Machado-Santos, A. R., Morais, M., Correia, J. S., Korostynski, M., Piechota, M., Stoffel, R., et al. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2014.176 · Cited by 57 · see citing works

Subtypes of depression among patients with Alzheimer's disease and other dementias

Castilla‐Puentes, R., & Habeych, M. E. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2009.04.1232 · Cited by 55 · see citing works

Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathway

Wang, Y.-J., Ren, Q.-G., Gong, W.-G., Wu, D., Tang, X., Li, X.-L., Wu, F., Bai, F., Xu, L., & Zhang, Z.-J. (2016) · OncoTarget · doi:10.18632/oncotarget.7798 · Cited by 55 · see citing works

Trajectories of depressive symptoms and their relationship to the progression of dementia

Barca, M. L., Persson, K., Eldholm, R. S., Benth, J. Š., Kersten, H., Knapskog, A., Saltvedt, I. T., Selbæk, G., & Engedal, K. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.07.008 · Cited by 55 · see citing works

Moclobemide exerts anti-inflammatory effect in lipopolysaccharide-activated primary mixed glial cell culture

Bielecka, A., Paul-Samojedny, M., & Obuchowicz, E. (2010) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-010-0535-4 · Cited by 44 · see citing works

Changes in tau phosphorylation levels in the hippocampus and frontal cortex following chronic stress

Yang, C., Guo, X.-L., Wang, G. H., Wang, H., Liu, Z. C., Liu, H., Zhu, Z., & Li, Y. (2014) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20133275 · Cited by 40 · see citing works

Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander?

Tan, Z. S., & Seshadri, S. (2010) · Alzheimer's Research & Therapy · doi:10.1186/alzrt29 · Cited by 39 · see citing works

Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

Li, Y., Zhang, Y., Liu, Y., Wang, H., Yuan, L., & Luo, Z.-P. (2004) · PubMed · Cited by 38 · see citing works

The effect of corticosteroids on amyloid β precursor protein/amyloid precursor-like protein expression and processing in vivo

Budas, G. R., Coughlan, C. M., Seckl, J. R., & Breen, K. C. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00790-9 · Cited by 37 · see citing works

Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3×TgAD mice

Sun, D., Gao, L., Jin, L., Wu, H., Wang, Q., Zhou, Y. L., Fan, S., Jiang, X., Ke, D., Lei, H. C., et al. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.08.037 · Cited by 36 · see citing works

Citalopram Ameliorates Impairments in Spatial Memory and Synaptic Plasticity in Female 3xTgAD Mice

Zhang, W., Junhong, G., Niu, X., Jie, W., Zhaojun, W., Meina, W., Yang, W., Zhang, J., & Qi, J. (2017) · BioMed Research International · doi:10.1155/2017/1238687 · Cited by 28 · see citing works

Escitalopram Ameliorates Forskolin-Induced Tau Hyperphosphorylation in HEK239/tau441 Cells

Ren, Q., Wang, Y., Gong, W.-G., Zhou, Q.-D., Xu, L., & Zhang, Z. (2015) · Journal of Molecular Neuroscience · doi:10.1007/s12031-015-0519-4 · Cited by 23 · see citing works

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.

Caraci, F., Pappalardo, G., Basile, L., Giuffrida, A., Copani, A., Tosto, R., Sinopoli, A., Giuffrida, M. L., Pirrone, E., Drago, F., et al. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.07.015 · Cited by 23 · see citing works

Pre-treatment with amitriptyline causes epigenetic up-regulation of neuroprotection-associated genes and has anti-apoptotic effects in mouse neuronal cells

Tran, N. Q. V., Nguyen, N. A., Takabe, K., Yamagata, Z., & Miyake, K. (2017) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2017.05.002 · Cited by 23 · see citing works

Impaired adult hippocampal neurogenesis and its partial reversal by chronic treatment of fluoxetine in a mouse model of Angelman syndrome

Godavarthi, S. K., Dey, P. N., Sharma, A., & Jana, N. R. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.07.103 · Cited by 17 · see citing works

Editorial Review. The genetics of Alzheimer?s disease? new opportunities and new challenges

Lovestone, S. (1996) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199606)11:6 · Cited by 10 · see citing works

A new voice for global neurology?

Neurology, T. L. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70347-3 · Cited by 8 · see citing works

Alzheimer’s disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

Monteiro, A. R., Barbosa, D. J., Remião, F., & Silva, R. V. D. S. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115522 · Cited by 358 · see citing works

The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology

Xie, J., Van Hoecke, L., & Vandenbroucke, R. E. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.796867 · Cited by 324 · see citing works

Chronic Stress and Oxidative Stress as Common Factors of the Pathogenesis of Depression and Alzheimer’s Disease: The Role of Antioxidants in Prevention and Treatment

Juszczyk, G., Mikulska, J., Kasperek, K., Pietrzak, D., Mrozek, W., & Herbet, M. (2021) · Antioxidants · doi:10.3390/antiox10091439 · Cited by 235 · see citing works

Ergothioneine, recent developments

Cheah, I. K.-M., & Halliwell, B. B. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101868 · Cited by 200 · see citing works

Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective

Mielke, M. M., Aggarwal, N. T., Vila‐Castelar, C., Agarwal, P., Arenaza‐Urquijo, E. M., Brett, B., Brugulat‐Serrat, A., DuBose, L. E., Eikelboom, W. S., Flatt, J., et al. (2022) · Alzheimer's & Dementia · doi:10.1002/alz.12662 · Cited by 198 · see citing works

Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer’s Disease

Gaitán, J. M., Moon, H. Y., Stremlau, M., Dubal, D. B., Cook, D. B., Okonkwo, O. C., & van Praag, H. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.660181 · Cited by 160 · see citing works

Biomedical knowledge graph learning for drug repurposing by extending guilt-by-association to multiple layers

Bang, D., Lim, S., Lee, S., & Kim, S. (2023) · Nature Communications · doi:10.1038/s41467-023-39301-y · Cited by 131 · see citing works

Molecular and functional properties of cortical astrocytes during peripherally induced neuroinflammation

Castro, B. D., Bernstein, A. M., Coppola, G., Sofroniew, M. V., & Khakh, B. S. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109508 · Cited by 115 · see citing works

Inter-relationship between cognitive performance and depressive symptoms and their association with quality of life in older adults: A network analysis based on the 2017–2018 wave of Chinese Longitudinal Healthy Longevity Survey (CLHLS)

Bai, W., Zhang, J., Smith, R. D., Cheung, T. C. C., Su, Z., Ng, C. H., Zhang, Q., & Xiang, Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.09.159 · Cited by 116 · see citing works

Untitled work

(2022) · doi:10.1016/j.biopsych.2022.08.026 · Cited by 113 · see citing works

Depression and Dementia in Older Adults: A Neuropsychological Review

Tetsuka, S. (2021) · Aging and Disease · doi:10.14336/ad.2021.0526 · Cited by 111 · see citing works

Modifiable Risk Factors in Alzheimer Disease and Related Dementias: A Review

Litke, R. R., Garcharna, L. C., Jiwani, S., & Neugroschl, J. A. (2021) · Clinical Therapeutics · doi:10.1016/j.clinthera.2021.05.006 · Cited by 109 · see citing works

Stress-Induced Depression and Alzheimer’s Disease: Focus on Astrocytes

Dolotov, O., Inozemtseva, L. S., Myasoedov, N., & Grivennikov, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094999 · Cited by 92 · see citing works

Alzheimer’s Disease and Inflammaging

Kosyreva, A., Sentyabreva, A., Tsvetkov, I., & Makarova, O. (2022) · Brain Sciences · doi:10.3390/brainsci12091237 · Cited by 98 · see citing works

A novel hybrid model in the diagnosis and classification of Alzheimer's disease using EEG signals: Deep ensemble learning (DEL) approach

Nour, M., Şentürk, Ü., & Polat, K. (2023) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2023.105751 · Cited by 93 · see citing works

A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y Cells

Rehfeldt, S. C. H., Laufer, S., & Goettert, M. I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073701 · Cited by 85 · see citing works

Predictors of depression among middle-aged and older men and women in Europe: A machine learning approach

Handing, E. P., Strobl, C., Jiao, Y., Feliciano, L., & Aichele, S. (2022) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2022.100391 · Cited by 81 · see citing works

Genetic Evidence Supporting a Causal Role of Depression in Alzheimer’s Disease

Harerimana, N. V., Liu, Y., Gerasimov, E. S., Duong, D. M., Beach, T. G., Reiman, E. M., Schneider, J. A., Boyle, P. A., Lori, A., Bennett, D. A., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.11.025 · Cited by 72 · see citing works

Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges

Wu, C., Yang, L., Feng, S., Zhu, L., Yang, L., Liu, T. C., & Duan, R. (2022) · Inflammation and Regeneration · doi:10.1186/s41232-022-00216-8 · Cited by 71 · see citing works

Pro-inflammatory cytokines in stress-induced depression: Novel insights into mechanisms and promising therapeutic strategies

Chang, J., Jiang, T., Shan, X., Zhang, M., Li, Y. Y., Qi, X., Bian, Y., & Zhao, L. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110931 · Cited by 70 · see citing works

Gut microbiome predicts cognitive function and depressive symptoms in late life

Kolobaric, A., Andreescu, C., Jašarević, E., Hong, C. H., Roh, H., Cheong, J. Y., Kim, Y., Shin, T. S., Kang, C. S., Kwon, C. O., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02551-3 · Cited by 62 · see citing works

Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer’s disease

Reddy, A. P., Yin, X., Sawant, N. A., & Reddy, P. H. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab054 · Cited by 55 · see citing works

Urban-rural disparities in the prevalence and trends of depressive symptoms among Chinese elderly and their associated factors

Wu, Y., Su, B., Chen, C., Zhao, Y., Zhong, P., & Zheng, X. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.07.117 · Cited by 57 · see citing works

Neuropsychiatric Symptoms in Mild Cognitive Impairment and Dementia Due to AD: Relation With Disease Stage and Cognitive Deficits

Wiels, W. A., Wittens, M. M. J., Zeeuws, D., Baeken, C., & Engelborghs, S. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.707580 · Cited by 52 · see citing works

Toward manipulating serotonin signaling via the microbiota–gut–brain axis

Everett, B. A., Tran, P., & Prindle, A. B. (2022) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2022.102826 · Cited by 52 · see citing works

Novel Concepts for Conformal Load-Bearing Antenna Structure

Callus, P. J. (2008) · Cited by 52 · see citing works

Risk of incident dementia varies with different onset and courses of depression

Lee, A. T. C., Fung, A. W. T., Richards, M., Chan, W. C., Chiu, H. F. K., Lee, R. S. Y., & LAM, L. C. W. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.12.195 · Cited by 49 · see citing works

c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer’s Diseases

Rehfeldt, S. C. H., Majolo, F., Goettert, M. I., & Laufer, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249677 · Cited by 46 · see citing works

Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease

Caruso, G., Grasso, M., Fidilio, A., Torrisi, S., Musso, N., Geraci, F., Tropea, M. R., Privitera, A., Tascedda, F., Puzzo, D., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.809541 · Cited by 51 · see citing works

Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model

Chen, C., Lu, J., Peng, W., Mak, S., Yang, Y., Zhu, Z., Wang, S., Hou, J., Zhou, X. J., Xin, W., et al. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.106003 · Cited by 51 · see citing works

The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer’s disease

Fronza, M. G., Alves, D. A. C., Praticò, D., & Savegnago, L. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102033 · Cited by 47 · see citing works

Effectiveness of Dance-Based Interventions on Depression for Persons With MCI and Dementia: A Systematic Review and Meta-Analysis

Wang, Y., Liu, M., Tan, Y., Dong, Z., Wu, J., Cui, H., Shen, D., & Chi, I. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.709208 · Cited by 43 · see citing works

Antidepressants in Alzheimer’s Disease: A Focus on the Role of Mirtazapine

Correia, A. S., & Vale, N. (2021) · Pharmaceuticals · doi:10.3390/ph14090930 · Cited by 37 · see citing works

The physician's Alzheimer's disease management guide: Early detection and diagnosis of cognitive impairment, Alzheimer's disease and related dementia

Reiss, A. B., Raphael, D. D. L., Chin, N. A., & Sinha, V. (2022) · AIMS Public Health · doi:10.3934/publichealth.2022047 · Cited by 40 · see citing works

Quercetin Ameliorates Cognitive Impairment in Depression by Targeting HSP90 to Inhibit NLRP3 Inflammasome Activation

Du, L., Fan, X., Yang, Y., Wu, S., & Liu, Y. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-03926-x · Cited by 39 · see citing works

Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling

Cong, Y.-F., Liu, F.-W., Xu, L., Song, S., Shen, X.-R., Liu, D., Hou, X.-Q., & Zhang, H. (2023) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyad042 · Cited by 38 · see citing works

Association of Midlife Depressive Symptoms with Regional Amyloid-β and Tau in the Framingham Heart Study

Gonzales, M. M., Samra, J. K., O’Donnell, A., Mackin, R. S., Salinas, J., Jacob, M. E., Satizábal, C. L., Aparicio, H. J., Thibault, E. G., Sanchez, J. S., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210232 · Cited by 37 · see citing works

Effectiveness of vortioxetine in patients with major depressive disorder and early-stage dementia: The MEMORY study

Christensen, M. C., Schmidt, S. N., & Grande, I. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.06.024 · Cited by 37 · see citing works

Association of amyloid-beta with depression or depressive symptoms in older adults without dementia: a systematic review and meta-analysis

Twait, E. L., Wu, J.-H., Kamarioti, M., Basten, M., van der Flier, W. M., Gerritsen, L., & Geerlings, M. I. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02739-9 · Cited by 39 · see citing works

Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer’s disease

Shu, S., Xu, S., Ye, L., Liu, Y., Cao, X., Jia, J., Bian, H.-J., Liu, Y., Zhu, X., & Xu, Y. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01435-w · Cited by 35 · see citing works

Later life depression as risk factor for developing dementia: epidemiological evidence, predictive models, preventive strategies and future trends

Piras, F., Banaj, N., Porcari, D. E., Piras, F., & Spalletta, G. (2021) · Minerva Medica · doi:10.23736/s0026-4806.21.07571-6 · Cited by 35 · see citing works

Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating Neural Stem Cell activity

Gillotin, S., Sahni, V., Lepko, T., Hanspal, M. A., Swartz, J., Alexopoulou, Z., & Marshall, F. H. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101447 · Cited by 32 · see citing works

Perspectives on the complex links between depression and dementia

Hakim, A. M. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.821866 · Cited by 33 · see citing works

Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model

Yang, L., Wu, C., Tucker, L. D., Dong, Y., Li, Y., Xu, P., & Zhang, Q. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201616 · Cited by 34 · see citing works

Antidepressant activity of rose oxide essential oil: possible involvement of serotonergic transmission

Maia, W. M. N., de Andrade, F. D. C. P., Filgueiras, L. A., Mendes, A. N., Assunção, A. F. C., Rodrigues, N. D. S., Marques, R. B., Filho, A. L. M. M., de Sousa, D. P., & Lopes, L. D. S. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e06620 · Cited by 32 · see citing works

Stress vulnerability shapes disruption of motor cortical neuroplasticity

Gellner, A., Sitter, A., Rackiewicz, M., Sylvester, M., Philipsen, A., Zimmer, A., & Stein, V. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01855-8 · Cited by 32 · see citing works

Cognitive Behavioral Therapy for Late-Life Depression (CBTlate): Results of a Multicenter, Randomized, Observer-Blinded, Controlled Trial

Dafsari, F. S., Bewernick, B., Böhringer, S., Domschke, K., Elsaesser, M., Löbner, M., Luppa, M., Preis, L., Püsken, J., Schmitt, S., et al. (2023) · Psychotherapy and Psychosomatics · doi:10.1159/000529445 · Cited by 30 · see citing works

Association of long-term air pollution and ambient noise with cognitive decline in the Heinz Nixdorf Recall study

Ogurtsova, K., Soppa, V., Weimar, C., Jöckel, K., Jokisch, M., & Hoffmann, B. H. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.121898 · Cited by 30 · see citing works

Divorce and physical health: A three-level meta-analysis

Pellón-Elexpuru, I., van Dijk, R., van der Valk, I. E., Martínez‐Pampliega, A., Molleda, A., & Cormenzana, S. (2024) · Social Science & Medicine · doi:10.1016/j.socscimed.2024.117005 · Cited by 44 · see citing works

The Utility of Assessing Health-Related Quality of Life to Predict Cognitive Decline and Dementia

Phyo, A. Z. Z., on behalf of the ASPREE Investigator Group, González‐Chica, D. A., Stocks, N., Storey, E., Woods, R. L., Murray, A. M., Orchard, S. G., Shah, R. C., Gašević, D., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201349 · Cited by 30 · see citing works

The associations between whole grain and refined grain intakes and serum C-reactive protein

Taskinen, R. E., Hantunen, S., Tuomainen, T., & Virtanen, J. K. (2021) · European Journal of Clinical Nutrition · doi:10.1038/s41430-021-00996-1 · Cited by 30 · see citing works

Brain FNDC5/Irisin Expression in Patients and Mouse Models of Major Depression

Lima‐Filho, R. A. S., Fortuna, J. T. S., Cozachenco, D., Isaac, A. R., Silva, N. M. L. E., Saldanha, A., Santos, L. E., Ferreira, S. T., Lourenco, M. V., & Felice, F. G. D. (2023) · eNeuro · doi:10.1523/eneuro.0256-22.2023 · Cited by 31 · see citing works

Positron emission tomography imaging of serotonin degeneration and beta-amyloid deposition in late-life depression evaluated with multi-modal partial least squares

Smith, G. S., Workman, C. I., Protas, H. D., Su, Y., Savonenko, A. V., Kuwabara, H., Gould, N. F., Kraut, M. A., Joo, J. H., Nandi, A., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01539-9 · Cited by 29 · see citing works

Pathophysiological Association of Alzheimer’s Disease and Hypertension: A Clinical Concern for Elderly Population

Yao, Q., Jiang, K., Lin, F., Zhu, T., Khan, N. H., & Jiang, E. (2023) · Clinical Interventions in Aging · doi:10.2147/cia.s400527 · Cited by 29 · see citing works

Disease severity and mortality in Alzheimer's disease: an analysis using the U.S. National Alzheimer’s Coordinating Center Uniform Data Set

Crowell, V., Reyes, A., Zhou, S. Q., Vassilaki, M. E., Gsteiger, S., & Gustavsson, A. (2023) · BMC Neurology · doi:10.1186/s12883-023-03353-w · Cited by 28 · see citing works

Distinguishing features of depression in dementia from primary psychiatric disease

Fisher, D. W., Dunn, J. T., & Dong, H. (2024) · Discover Mental Health · doi:10.1007/s44192-023-00057-y · Cited by 30 · see citing works

The impact of immersive virtual reality meditation for depression and anxiety among inpatients with major depressive and generalized anxiety disorders

Lee, J., Kim, J., & Ory, M. G. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1471269 · Cited by 29 · see citing works

Psychotherapeutic interventions in individuals at risk for Alzheimer’s dementia: a systematic review

Rostamzadeh, A., Kahlert, A., Kalthegener, F., & Jessen, F. (2022) · Alzheimer's Research & Therapy · doi:10.1186/s13195-021-00956-8 · Cited by 26 · see citing works

Neurological and mental health consequences of COVID-19: potential implications for well-being and labour force

Meier, I. B., Teixeira, C. V. L., Tarnanas, I., Mirza, F., & Rajendran, L. (2021) · Brain Communications · doi:10.1093/braincomms/fcab012 · Cited by 26 · see citing works

Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study

Preez, A. D., Lefèvre‐Arbogast, S., González‐Domínguez, R., Houghton, V., de Lucia, C., Low, D. Y., Helmer, C., Féart, C., Delcourt, C., Proust‐Lima, C., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01644-1 · Cited by 27 · see citing works

Once-Daily Subcutaneous Irisin Administration Mitigates Depression- and Anxiety-like Behavior in Young Mice

Pignataro, P., Dicarlo, M., Suriano, C., Sanesi, L., Zerlotin, R., Storlino, G., Oranger, A., Zecca, C., Dell’Abate, M. T., Mori, G., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076715 · Cited by 26 · see citing works

Dementia Prevention in Clinical Practice

Niotis, K., Akiyoshi, K., Carlton, C., & Isaacson, R. (2022) · Seminars in Neurology · doi:10.1055/s-0042-1759580 · Cited by 25 · see citing works

Pathogenesis of miR-155 on nonmodifiable and modifiable risk factors in Alzheimer’s disease

Liu, J.-J., Long, Y.-F., Xu, P., Guo, H.-D., & Cui, G.-H. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01264-z · Cited by 25 · see citing works

Molecular bases of comorbidities: present and future perspectives

Sánchez-Valle, J., & Valencia, A. (2023) · Trends in Genetics · doi:10.1016/j.tig.2023.06.003 · Cited by 24 · see citing works

Bidirectional crosstalk between microglia and serotonin signaling in neuroinflammation and CNS disorders

Zheng, Y., & Xu, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1646740 · Cited by 25 · see citing works

Molecular imaging of beta-amyloid deposition in late-life depression

Smith, G. S., Kuwabara, H., Nandi, A., Gould, N. F., Nassery, N., Savonenko, A. V., Joo, J. H., Kraut, M. A., Brašić, J. R., Holt, D. P., et al. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.01.002 · Cited by 25 · see citing works

Ensemble feature selection with data-driven thresholding for Alzheimer's disease biomarker discovery

Spooner, A., Mohammadi, G., Sachdev, P. S., Brodaty, H., Sowmya, A., & Initiative, A. D. N. (2023) · BMC Bioinformatics · doi:10.1186/s12859-022-05132-9 · Cited by 24 · see citing works

CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk

Liao, Y., Wang, Y., Tao, Q.-Q., Yang, C., Wang, J.-L., Cheng, J.-B., Ma, J., Wu, Z.-Y., Pan, R., & Yuan, Z.-Q. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.13366 · Cited by 19 · see citing works

Association between antidepressants and dementia risk in older adults with depression: a systematic review and meta-analysis

Wang, G. H.-M., Li, P., Wang, Y., Guo, J., Wilson, D. L., & Lo-Ciganic, W.-H. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12196342 · Cited by 23 · see citing works

Converged avenues: depression and Alzheimer’s disease– shared pathophysiology and novel therapeutics

Bajaj, S., & Mahesh, R. (2024) · Molecular Biology Reports · doi:10.1007/s11033-023-09170-1 · Cited by 23 · see citing works

Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease

Tag, S. H., Kim, B., Bae, J., Chang, K., & Im, H. (2022) · Molecular Brain · doi:10.1186/s13041-022-00933-8 · Cited by 22 · see citing works

Intranasal interferon-beta alleviates anxiety and depressive-like behaviors by modulating microglia polarization in an Alzheimer's disease model

Farhangian, M., Azarafrouz, F., Chavoshinezhad, S., & Dargahi, L. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136968 · Cited by 21 · see citing works

Associations between psychological therapy outcomes for depression and incidence of dementia

John, A., Saunders, R., Desai, R., Bell, G., Fearn, C., Buckman, J. E. J., Brown, B., Nurock, S., Michael, S., Ware, P., et al. (2022) · Psychological Medicine · doi:10.1017/s0033291722002537 · Cited by 21 · see citing works

Alzheimer’s disease risk reduction in clinical practice: a priority in the emerging field of preventive neurology

Niotis, K., Saperia, C., Saif, N., Carlton, C., & Isaacson, R. (2024) · Nature Mental Health · doi:10.1038/s44220-023-00191-0 · Cited by 20 · see citing works

Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseases

Haniff, Z. R., Bocharova, M., Mantingh, T., Rucker, J., Velayudhan, L., Taylor, D. M., Young, A. H., Aarsland, D., Vernon, A. C., & Thuret, S. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108641 · Cited by 21 · see citing works

Effects of three-duration Tai-Chi exercises on depression and sleep quality in older women

Chang, S.-W., Cheng, L., & Liu, H.-X. (2024) · European Geriatric Medicine · doi:10.1007/s41999-024-00981-4 · Cited by 23 · see citing works

Exploring the L-shaped relationship between Atherogenic Index of Plasma and depression: Results from NHANES 2005–2018

Zhang, H., Zhang, G., & Fu, J. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.073 · Cited by 21 · see citing works

Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders

Wen, J., Skampardoni, I., Tian, Y., Yang, Z., Cui, Y., Erus, G., Hwang, G., Varol, E., Boquet-Pujadas, A., Chand, G. B., et al. (2025) · Nature Biomedical Engineering · doi:10.1038/s41551-025-01412-w · Cited by 19 · see citing works

The trajectories of depressive symptoms and subsequent incident dementia, coronary heart diseases, stroke and all-cause mortality

Wu, T., Li, C., Zhu, Y., Ma, Y., Hua, R., Zhong, B., & Xie, W. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.06.001 · Cited by 19 · see citing works

Sleep duration, sleep efficiency, and amyloid β among cognitively healthy later-life adults: a systematic review and meta-analysis

Moon, C., Schneider, A. C., Cho, Y.-E., Zhang, M., Dang, H., & Vu, K. (2024) · BMC Geriatrics · doi:10.1186/s12877-024-05010-4 · Cited by 19 · see citing works

Could α-Klotho Unlock the Key Between Depression and Dementia in the Elderly: from Animal to Human Studies

Gao, X., Li, Y., Sun, Z., Xu, H., Ma, G., Deng, Q., Zhang, C. X., & Li, R. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02313-0 · Cited by 18 · see citing works

Alzheimer’s disease and depression in the elderly: A trajectory linking gut microbiota and serotonin signaling

Cutuli, D., Giacovazzo, G., Decandia, D., & Coccurello, R. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1010169 · Cited by 16 · see citing works

Does resveratrol improve cognition in humans? A scientometric study to an in‐depth review

Tu, W., Song, M., & Fan, X. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14276 · Cited by 17 · see citing works

Change in Depressive Symptoms and Longitudinal Regional Amyloid Accumulation in Unimpaired Older Adults

Munro, C. E., Farrell, M. E., Hanseeuw, B. J., Rentz, D. M., Buckley, R. F., Properzi, M. J., Yuan, Z., Vannini, P., Amariglio, R. E., Quiroz, Y. T., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.27248 · Cited by 20 · see citing works

The role of plasma inflammatory markers in late-life depression and conversion to dementia: a 3-year follow-up study

Bocharova, M., Borza, T., Watne, L. O., Engedal, K., O'Brien, J. T., Selbæk, G., Idland, A., Hodsoll, J. P., Young, A. H., & Aarsland, D. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02908-2 · Cited by 19 · see citing works

Impact of Integrated Care Pathways Within the Framework of Collaborative Care on Older Adults With Anxiety, Depression, or Mild Cognitive Impairment

Dham, P., McAiney, C. A., Saperson, K., Wang, W., Malik, N., Parascandalo, F., Zhao, H., Lourenço, L., Oliver, D., Kates, N., et al. (2022) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2022.01.010 · Cited by 17 · see citing works

From Mild Cognitive Impairment to Dementia: The Impact of Comorbid Conditions on Disease Conversion

Menegon, F., Marchi, F. D., Aprile, D., Zanelli, I., Decaroli, G., Comi, C., & Tondo, G. (2024) · Biomedicines · doi:10.3390/biomedicines12081675 · Cited by 17 · see citing works

Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

Liu, X., Wang, H., Tian, X., Luo, Y., Ma, M., Zheng, Z., Wang, Y., Shi, F., Wang, Q., Xu, Z. F., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03488-2 · Cited by 16 · see citing works

Glucocorticoids, synaptic plasticity and Alzheimer’s disease

Klyubin, I., Ondrejcak, T., Hu, N.-W., & Rowan, M. J. (2022) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2022.100365 · Cited by 16 · see citing works

Pinus halepensis Essential Oil Ameliorates Aβ1-42-Induced Brain Injury by Diminishing Anxiety, Oxidative Stress, and Neuroinflammation in Rats

Postu, P. A., Mihăşan, M., Gorgan, L., Sadiki, F. Z., Idrissi, M. E., & Hriţcu, L. (2022) · Biomedicines · doi:10.3390/biomedicines10092300 · Cited by 16 · see citing works

Reduced Plasma Levels of α-Klotho and Their Correlation With Klotho Polymorphisms in Elderly Patients With Major Depressive Disorders

Gao, X., Sun, Z., Ma, G., Li, Y., Liu, M., Zhang, G., Xu, H., Gao, Y., Zhou, J., Deng, Q., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.682691 · Cited by 16 · see citing works

Structural variants linked to Alzheimer’s disease and other common age-related clinical and neuropathologic traits

Vialle, R. A., Lopes, K. D. P., Li, Y., Ng, B., Schneider, J. A., Buchman, A. S., Wang, Y., Farfel, J. M., Barnes, L. L., Wingo, A. P., et al. (2025) · Genome Medicine · doi:10.1186/s13073-025-01444-6 · Cited by 16 · see citing works

Inhibition Of Tau Protein Aggregation By a Chaperone-like β-Boswellic Acid Conjugated To Gold Nanoparticles

Gharb, M., Nouralishahi, A., Riazi, A., & Riazi, G. H. (2022) · ACS Omega · doi:10.1021/acsomega.2c03616 · Cited by 15 · see citing works

Adolescent neurodevelopment and psychopathology: The interplay between adversity exposure and genetic risk for accelerated brain ageing

Petrican, R., & Fornito, A. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101229 · Cited by 15 · see citing works

Predicting Dementia Risk Factors Based on Feature Selection and Neural Networks

Javeed, A., Dallora, A. L., Berglund, J. S., Ali, A., Anderberg, P., & Ali, L. (2023) · Computers, materials & continua/Computers, materials & continua (Print) · doi:10.32604/cmc.2023.033783 · Cited by 15 · see citing works

Exploring the Relationship of Leisure Travel with Loneliness, Depression, and Cognitive Function in Older Adults

Cole, S. T., Hua, C., Peng, S., & Wang, W. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21040498 · Cited by 15 · see citing works

Therapeutic implications of hypothalamic-pituitaryadrenal-axis modulation in Alzheimer’s disease: A narrative review of pharmacological and lifestyle interventions

Watermeyer, T., Robb, C. E., Gregory, S., & Udeh‐Momoh, C. T. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2020.100877 · Cited by 15 · see citing works

Effectiveness of vortioxetine in patients with major depressive disorder and comorbid Alzheimer’s disease in routine clinical practice: An analysis of a post-marketing surveillance study in South Korea

Cumbo, E., Adair, M., Åström, D. O., & Christensen, M. C. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1037816 · Cited by 14 · see citing works

Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants

Upadhya, S., Liu, H., Luo, S., Lutz, M. W., & Chiba‐Falek, O. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.827447 · Cited by 15 · see citing works

Chronic stress, gut microbiota, and immunity: interconnections and implications for health

Jia, H., Guo, X., Wei, Y., Can, C., He, N., Zhang, H., Yang, X., Wu, H., Liu, W., & Ma, D. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05376-y · Cited by 14 · see citing works

Antidepressants to Prevent the Progression of Depressive Dementia to Alzheimer’s Disease: Evaluating the Degree of Knowledge about this Topic

Hussein, W., Alshammari, M. D., Alheibshy, F., Alsadiq, A. A., Almubalea, R. S., Alanazi, F. K., & Almarshdi, M. F. (2025) · Asian Journal of Pharmaceutical Research and Health Care · doi:10.4103/ajprhc.ajprhc_138_25

Depression in Alzheimer's Disease: Epidemiology, Mechanisms, and Management

Chi, S., Yu, J., Tan, M., & Tan, L. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-140324 · Cited by 165 · see citing works

Pharmacological Treatment of Depression in Alzheimer’s Disease: A Challenging Task

Cassano, T., Calcagnini, S., Carbone, A., Bukke, V. N., Orkisz, S., Villani, R., Romano, A., Avolio, C., & Gaetani, S. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01067 · Cited by 43 · see citing works

Depressive Symptoms in Clinical and Incipient Alzheimer's Disease

Hsiao, J. J., & Teng, E. (2013) · Neurodegenerative Disease Management · doi:10.2217/nmt.13.10 · Cited by 17 · see citing works

What is the association between depression and Alzheimer’s disease?

Tsuno, N., & Homma, A. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.106 · Cited by 112 · see citing works