Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats

QIIME allows analysis of high-throughput community sequencing data

Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887 · see citing works

Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy

Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 19,946 · see citing works

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444 · see citing works

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

(1998) · The Lancet · doi:10.1016/s0140-6736(98)07037-8 · Cited by 8,247 · see citing works

UniFrac: a New Phylogenetic Method for Comparing Microbial Communities

Lozupone, C., & Knight, R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8228-8235.2005 · Cited by 8,227 · see citing works

A metagenome-wide association study of gut microbiota in type 2 diabetes

Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., et al. (2012) · Nature · doi:10.1038/nature11450 · Cited by 6,762 · see citing works

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245 · see citing works

Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13505 · Cited by 5,652 · see citing works

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579 · see citing works

Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice

Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819 · see citing works

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

(1998) · PubMed · Cited by 4,290 · see citing works

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C., Rolph, M. S., Mackay, F., Artis, D., et al. (2009) · Nature · doi:10.1038/nature08530 · Cited by 3,241 · see citing works

Diagnosis of multiple cancer types by shrunken centroids of gene expression

Tibshirani, R. J., Hastie, T. J., Narasimhan, B., & Chu, G. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082099299 · Cited by 2,938 · see citing works

Introducing DOTUR, a Computer Program for Defining Operational Taxonomic Units and Estimating Species Richness

Schloss, P. D., & Handelsman, J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.3.1501-1506.2005 · Cited by 2,503 · see citing works

Metformin and reduced risk of cancer in diabetic patients

Evans, J. M. M., Donnelly, L. A., Emslie-Smith, A. M., Alessi, D. R., & Morris, A. D. (2005) · BMJ · doi:10.1136/bmj.38415.708634.f7 · Cited by 2,388 · see citing works

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P., & Duncan, S. H. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.156 · Cited by 2,203 · see citing works

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

Vijay-Kumar, M., Aitken, J. D., Carvalho, F. A., Cullender, T. C., Mwangi, S., Srinivasan, S., Sitaraman, S. V., Knight, R., Ley, R. E., & Gewirtz, A. T. (2010) · Science · doi:10.1126/science.1179721 · Cited by 2,068 · see citing works

The Long-Term Stability of the Human Gut Microbiota

Faith, J. J., Guruge, J. L., Charbonneau, M., Subramanian, S., Seedorf, H., Goodman, A. L., Clemente, J. C., Knight, R., Heath, A. C., Leibel, R. L., et al. (2013) · Science · doi:10.1126/science.1237439 · Cited by 2,058 · see citing works

An increase in the <i>Akkermansia</i> spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

Shin, N.-R., Lee, J.-C., Lee, H.-Y., Kim, M.-S., Whon, T. W., Lee, M.-S., & Bae, J.-W. (2014) · Gut · doi:10.1136/gutjnl-2012-303839 · Cited by 1,550 · see citing works

Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

Biagi, E., Nylund, L., Candela, M., Ostan, R., Bucci, L., Pini, E., Nikkïla, J., Monti, D., Satokari, R., Franceschi, C., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010667 · Cited by 1,483 · see citing works

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., Wang, Y., Wang, Z., Si, S., Pan, H., et al. (2004) · Nature Medicine · doi:10.1038/nm1135 · Cited by 1,391 · see citing works

Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers

Wang, T., Cai, G., Qiu, Y., Fei, N., Zhang, M., Pang, X., Jia, W., Cai, S., & Zhao, L. (2012) · The ISME Journal · doi:10.1038/ismej.2011.109 · Cited by 1,287 · see citing works

Distribution of bacterioplankton in meromictic Lake Saelenvannet, as determined by denaturing gradient gel electrophoresis of PCR-amplified gene fragments coding for 16S rRNA

Øvreås, L., Forney, L. J., Daae, F. L., & Torsvik, V. L. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.9.3367-3373.1997 · Cited by 1,243 · see citing works

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054 · see citing works

NAST: a multiple sequence alignment server for comparative analysis of 16S rRNA genes

DeSantis, T. Z., Hugenholtz, P., Keller, K., Brodie, E., Larsen, N., Piceno, Y. M., Phan, R., & Andersen, G. L. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl244 · Cited by 1,028 · see citing works

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

Zhang, C., Zhang, M., Wang, S., Han, R., Cao, Y., Hua, W., Mao, Y., Zhang, X., Pang, X., Wei, C., et al. (2010) · The ISME Journal · doi:10.1038/ismej.2009.112 · Cited by 1,024 · see citing works

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism

Cabreiro, F., Au, C., Leung, K.-Y., Vergara-Irigaray, N., Cochemé, H. M., Noori, T., Weinkove, D., Schuster, E., Greene, N. D. E., & Gems, D. (2013) · Cell · doi:10.1016/j.cell.2013.02.035 · Cited by 967 · see citing works

Targeting gut microbiota in obesity: effects of prebiotics and probiotics

Delzenne, N. M., Neyrinck, A. M., Bäckhed, F., & Cani, P. D. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2011.126 · Cited by 783 · see citing works

Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice

Wang, J.-J., Tang, H., Zhang, C.-H., Zhao, Y., Derrien, M., Rocher, E., Vlieg, J. V. V. H., Strissel, K., Zhao, L.-P., Obin, M., et al. (2014) · The ISME Journal · doi:10.1038/ismej.2014.99 · Cited by 774 · see citing works

An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice

Fei, N., & Zhao, L.-P. (2012) · The ISME Journal · doi:10.1038/ismej.2012.153 · Cited by 713 · see citing works

Metformin in non-alcoholic steatohepatitis.

Marchesini, G., Bianchi, G., Tomassetti, S., Zoli, M., & Melchionda, N. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06042-1 · Cited by 682 · see citing works

Rapidly denoising pyrosequencing amplicon reads by exploiting rank-abundance distributions

Reeder, J., & Knight, R. D. (2010) · Nature Methods · doi:10.1038/nmeth0910-668b · Cited by 679 · see citing works

Metformin Effects on Clinical Features, Endocrine and Metabolic Profiles, and Insulin Sensitivity in Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled 6-Month Trial, followed by Open, Long-Term Clinical Evaluation¹

Moghetti, P., Castello, R., Negri, C., Tosi, F., Perrone, F., Caputo, M., Zanolin, E., & Muggeo, M. (2000) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.85.1.6293 · Cited by 660 · see citing works

The contributory role of gut microbiota in cardiovascular disease

Tang, W. H. W., & Hazen, S. L. (2014) · Journal of Clinical Investigation · doi:10.1172/jci72331 · Cited by 641 · see citing works

Clinical Pharmacokinetics of Metformin

Scheen, A. J. (1996) · Clinical Pharmacokinetics · doi:10.2165/00003088-199630050-00003 · Cited by 640 · see citing works

Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats

Zhang, X., Zhao, Y., Zhang, M., Pang, X., Xu, J., Kang, C., Li, M., Zhang, C., Zhang, Z., Zhang, Y., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042529 · Cited by 615 · see citing works

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

Everard, A., Lazarevic, V., Gaïa, N., Johansson, M., Ståhlman, M., Backhed, F., Delzenne, N. M., Schrenzel, J., François, P., & Cani, P. D. (2014) · The ISME Journal · doi:10.1038/ismej.2014.45 · Cited by 598 · see citing works

Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine

Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., Huo, L., Wang, M., Hong, J., Wu, P., et al. (2008) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2007-2404 · Cited by 573 · see citing works

Impact of Intensive Lifestyle and Metformin Therapy on Cardiovascular Disease Risk Factors in the Diabetes Prevention Program

The Diabetes Prevention Program Research Group (2005) · Diabetes Care · doi:10.2337/diacare.28.4.888 · Cited by 572 · see citing works

Rapid determination of short‐chain fatty acids in colonic contents and faeces of humans and rats by acidified water‐extraction and direct‐injection gas chromatography

Zhao, G., NYMAN, M. E., & Jönsson, J. Å. (2005) · Biomedical Chromatography · doi:10.1002/bmc.580 · Cited by 531 · see citing works

Structural modulation of gut microbiota in life-long calorie-restricted mice

Zhang, C., Li, S., Yang, L., Huang, P., Li, W., Wang, S., Zhao, G., Zhang, M. H., Pang, X., Yan, Z., et al. (2013) · Nature Communications · doi:10.1038/ncomms3163 · Cited by 496 · see citing works

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations

Tang, J., Feng, Y., Tsao, S., Wang, N., Curtain, R., & Wang, Y. (2009) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2009.08.009 · Cited by 491 · see citing works

Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein

He, L., Sabet, A., Djedjos, S., Miller, R., Sun, X., Hussain, M. A., Radovick, S., & Wondisford, F. E. (2009) · Cell · doi:10.1016/j.cell.2009.03.016 · Cited by 479 · see citing works

Interplay Between Weight Loss and Gut Microbiota Composition in Overweight Adolescents

Santacruz, A., Marcos, A., Wärnberǵ, J., Martí, A., Martín‐Matillas, M., Campoy, C., Moreno, L. A., Veiga, Ó. L., Redondo-Figuero, C. G., Garagorri, J. M., et al. (2009) · Obesity · doi:10.1038/oby.2009.112 · Cited by 474 · see citing works

PCR Biases Distort Bacterial and Archaeal Community Structure in Pyrosequencing Datasets

Pinto, A. J., & Raskin, L. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043093 · Cited by 439 · see citing works

Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula

Xu, J. Y., Lian, F., Zhao, L., Zhao, Y., Chen, X., Zhang, X., Guo, Y., Zhang, C., Zhou, Q., Xue, Z., et al. (2014) · The ISME Journal · doi:10.1038/ismej.2014.177 · Cited by 423 · see citing works

Responses of gut microbiota to diet composition and weight loss in lean and obese mice

Ravussin, Y., Koren, O., Spor, A., LeDuc, C., Gutman, R., Stombaugh, J., Knight, R., Ley, R. E., & Leibel, R. L. (2012) · Obesity · doi:10.1038/oby.2011.111 · Cited by 406 · see citing works

Effect of Metformin on Metabolic Improvement and Gut Microbiota

Lee, H., & Ko, G. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.01357-14 · Cited by 387 · see citing works

A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome

Xiao, S., Fei, N., Pang, X., Shen, J., Wang, L., Zhang, B., Zhang, M. H., Zhang, X., Zhang, C., Li, M., et al. (2013) · FEMS Microbiology Ecology · doi:10.1111/1574-6941.12228 · Cited by 378 · see citing works

Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus

Napolitano, A., Miller, S. L., Nicholls, A. W., Baker, D., Horn, S. V., Thomas, E., Rajpal, D. K., Spivak, A., Brown, J. R., & Nunez, D. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100778 · Cited by 283 · see citing works

Obesity and gut flora

Bajzer, M., & Seeley, R. J. (2006) · Nature · doi:10.1038/4441009a · Cited by 196 · see citing works

Determination of berberine in human plasma by liquid chromatography–electrospray ionization–mass spectrometry

Hua, W., Ding, L., Chen, Y., Gong, B., He, J., & Xu, G. (2007) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2007.03.022 · Cited by 192 · see citing works

Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice

Xie, W., Gu, D., Li, J., Cui, K., & Zhang, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024520 · Cited by 183 · see citing works

Berberine on metabolic and cardiovascular risk factors: An analysis from preclinical evidences to clinical trials

Derosa, G., Maffioli, P., & Cicero, A. F. (2012) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2012.704014 · Cited by 171 · see citing works

Dose-Independent Pharmacokinetics of Metformin in Rats: Hepatic and Gastrointestinal First-Pass Effects

Choi, Y. H., Kim, S. G., & Lee, M. G. (2006) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20744 · Cited by 129 · see citing works

Isotretinoin and fenofibrate induce adiposity with distinct effect on metabolic profile in a rat model of the insulin resistance syndrome

Šedová, L., Šeda, O., Krenová, D., Křen, V., & Kazdová, L. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802613 · Cited by 31 · see citing works

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Wu, H., Esteve, E., Tremaroli, V., Khan, M. T., Caesar, R., Mannerås-Holm, L., Ståhlman, M., Olsson, L. M., Serino, M., Planas-Fèlix, M., et al. (2017) · Nature Medicine · doi:10.1038/nm.4345 · Cited by 1,632 · see citing works

Blautia —a new functional genus with potential probiotic properties?

Liu, X., Mao, B., Gu, J., Wu, J., Cui, S., Wang, G., Zhao, J., Zhang, H., & Chen, W. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1875796 · Cited by 1,398 · see citing works

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

Sun, L., Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0222-4 · Cited by 1,011 · see citing works

Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading <i>Akkermansia muciniphila</i> and Several Short-Chain Fatty Acid–Producing Microbiota in the Gut

de la Cuesta-Zuluaga, J., Mueller, N. T., Corrales-Agudelo, V., Velásquez-Mejía, E. P., Carmona, J. A., Abad, J. M., & Escobar, J. S. (2017) · Diabetes Care · doi:10.2337/dc16-1324 · Cited by 704 · see citing works

Metformin: update on mechanisms of action and repurposing potential

Foretz, M., Guigas, B., & Viollet, B. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00833-4 · Cited by 744 · see citing works

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Foretz, M., Guigas, B., & Viollet, B. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0242-2 · Cited by 686 · see citing works

Metformin and Its Benefits for Various Diseases

Lv, Z., & Guo, Y. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00191 · Cited by 544 · see citing works

Biological properties and clinical applications of berberine

Song, D., Hao, J., & Fan, D. (2020) · Frontiers of Medicine · doi:10.1007/s11684-019-0724-6 · Cited by 510 · see citing works

The quest to slow ageing through drug discovery

Partridge, L., Fuentealba, M., & Kennedy, B. K. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-0067-7 · Cited by 468 · see citing works

Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics

Feng, X., Sureda, A., Jafari, S., Memariani, Z., Tewari, D., Annunziata, G., Barrea, L., Hassan, S. T. S., Šmejkal, K., Malaník, M., et al. (2019) · Theranostics · doi:10.7150/thno.30787 · Cited by 465 · see citing works

Metabolism and Metabolic Disorders and the Microbiome: The Intestinal Microbiota Associated With Obesity, Lipid Metabolism, and Metabolic Health—Pathophysiology and Therapeutic Strategies

Aron-Wisnewsky, J., Warmbrunn, M. V., Nieuwdorp, M., & Clément, K. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.10.057 · Cited by 452 · see citing works

Gut microbiome and type 2 diabetes: where we are and where to go?

Sharma, S., & Tripathi, P. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.10.003 · Cited by 430 · see citing works

Metformin: Mechanisms in Human Obesity and Weight Loss

Yerevanian, A., & Soukas, A. A. (2019) · Current Obesity Reports · doi:10.1007/s13679-019-00335-3 · Cited by 414 · see citing works

Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities

Zeng, Q., Li, D., He, Y., Li, Y., Yang, Z., Zhao, X., Liu, Y., Wang, Y. H. D., Sun, J., Feng, X., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-49462-w · Cited by 409 · see citing works

Phascolarctobacterium faecium abundant colonization in human gastrointestinal tract

Wu, F., Guo, X., Zhang, J., Zhang, M., Ou, Z., & Peng, Y. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.4878 · Cited by 403 · see citing works

Structural Alteration of Gut Microbiota during the Amelioration of Human Type 2 Diabetes with Hyperlipidemia by Metformin and a Traditional Chinese Herbal Formula: a Multicenter, Randomized, Open Label Clinical Trial

Tong, X., Xu, J. Y., Lian, F., Yu, X., Zhao, Y., Xu, L., Zhang, M. H., Zhao, X., Shen, J., Wu, S., et al. (2018) · mBio · doi:10.1128/mbio.02392-17 · Cited by 376 · see citing works

Research progress on berberine with a special focus on its oral bioavailability

Liu, C.-S., Zheng, Y.-R., Zhang, Y.-F., & Long, X.-Y. (2016) · Fitoterapia · doi:10.1016/j.fitote.2016.02.001 · Cited by 363 · see citing works

Berberine pharmacology and the gut microbiota: A hidden therapeutic link

Habtemariam, S. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104722 · Cited by 352 · see citing works

The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids

Huang, P., Zhang, Y., Xiao, K., Jiang, F., Wang, H., Tang, D., Liu, D., Liu, B., Liu, Y., He, X., et al. (2018) · Microbiome · doi:10.1186/s40168-018-0590-5 · Cited by 339 · see citing works

Advancing functional and translational microbiome research using meta-omics approaches

Zhang, X., Li, L., Butcher, J., Stintzi, A. P., & Figeys, D. (2019) · Microbiome · doi:10.1186/s40168-019-0767-6 · Cited by 342 · see citing works

Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota

Xu, J., Chen, H., & Li, S. (2017) · Medicinal Research Reviews · doi:10.1002/med.21431 · Cited by 340 · see citing works

Blueberry polyphenols extract as a potential prebiotic with anti-obesity effects on C57BL/6 J mice by modulating the gut microbiota

Jiao, X., Wang, Y., Lin, Y., Lang, Y., Li, E., Zhang, X., Zhang, Q., Feng, Y., Meng, X., & Li, B. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.07.008 · Cited by 310 · see citing works

Resveratrol-induced gut microbiota reduces obesity in high-fat diet-fed mice

Wang, P., Li, D., Ke, W., Liang, D., Hu, X., & Chen, F. (2020) · International Journal of Obesity · doi:10.1038/s41366-019-0332-1 · Cited by 301 · see citing works

In vitro digestion under simulated saliva, gastric and small intestinal conditions and fermentation by human gut microbiota of polysaccharides from the fruits of Lycium barbarum

Ding, Y., Yan, Y., Peng, Y., Chen, D., Mi, J., Lu, L., Luo, Q., Li, X., Zeng, X., & Cao, Y. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.12.081 · Cited by 291 · see citing works

Differential changes in gut microbiota after gastric bypass and sleeve gastrectomy bariatric surgery vary according to diabetes remission

Murphy, R., Tsai, P., Jüllig, M., Liu, A., Plank, L., & Booth, M. (2017) · Obesity Surgery · doi:10.1007/s11695-016-2399-2 · Cited by 285 · see citing works

Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway

Bauer, P. V., Duca, F. A., Waise, T. M. Z., Rasmussen, B. A., Abraham, M. A., Dranse, H. J., Puri, A., O’Brien, C. A., & Lam, T. K. T. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2017.09.019 · Cited by 265 · see citing works

Gut microbiota-derived short-chain fatty acids and colorectal cancer: Ready for clinical translation?

Hou, H., Chen, D., Zhang, K., Zhang, W., Liu, T., Wang, S., Dai, X., Wang, B., Zhong, W., & Cao, H. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.11.027 · Cited by 270 · see citing works

Systematic review: human gut dysbiosis induced by non-antibiotic prescription medications

Le Bastard, Q., Al‐Ghalith, G. A., Grégoire, M., Chapelet, G., Javaudin, F., Dailly, E., Batard, E., Knights, D., & Montassier, E. (2018) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1111/apt.14451 · Cited by 263 · see citing works

Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation

Sang, T., Guo, C., Guo, D., Wu, J., Wang, Y., Wang, Y., Chen, J., Chen, C., Wu, K., Na, K., et al. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117594 · Cited by 268 · see citing works

Dietary fucoidan improves metabolic syndrome in association with increased Akkermansia population in the gut microbiota of high-fat diet-fed mice

Shang, Q., Song, G., Zhang, M., Shi, J., Xu, C., Hao, J., Li, G., & Yu, G. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2016.11.002 · Cited by 258 · see citing works

Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe−/− mice

Zhu, L., Zhang, D., Zhu, H., Zhu, J., Weng, S., Dong, L., Liu, T., Hu, Y., & Shen, X. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.11.023 · Cited by 243 · see citing works

Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence

Xu, X., Yi, H., Wu, J., Kuang, T., Zhang, J., Li, Q., Du, H., Xu, T., Jiang, G., & Fan, G. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110984 · Cited by 246 · see citing works

Metformin: An Old Drug with New Applications

Zhou, J. Y., Massey, S., Story, D. T., & Li, L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102863 · Cited by 236 · see citing works

A proliferative probiotic Bifidobacterium strain in the gut ameliorates progression of metabolic disorders via microbiota modulation and acetate elevation

Aoki, R., Kamikado, K., Suda, W., Takii, H., Mikami, Y., Suganuma, N., Hattori, M., & Koga, Y. (2017) · Scientific Reports · doi:10.1038/srep43522 · Cited by 225 · see citing works

Herbal drug discovery for the treatment of nonalcoholic fatty liver disease

Yan, T., Yan, N., Wang, P., Xia, Y., Hao, H., Wang, G., & Gonzalez, F. J. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.11.017 · Cited by 225 · see citing works

Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis

Jing, Y., Yu, Y., Bai, F., Wang, L., Yang, D., Zhang, C., Qin, C., Yang, M., Zhang, D., Zhu, Y., et al. (2021) · Microbiome · doi:10.1186/s40168-021-01007-y · Cited by 225 · see citing works

Lactobacillus acidophilus alleviates type 2 diabetes by regulating hepatic glucose, lipid metabolism and gut microbiota in mice

Yan, F., Li, N., Shi, J., Li, H., Yue, Y., Jiao, W., Wang, N., Song, Y., Huo, G., & Li, B. (2019) · Food & Function · doi:10.1039/c9fo01062a · Cited by 225 · see citing works

The promise of the gut microbiome as part of individualized treatment strategies

Schupack, D. A., Mars, R. A. T., Voelker, D. H., Abeykoon, J. P., & Kashyap, P. C. (2022) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-021-00499-1 · Cited by 217 · see citing works

Oral hydroxysafflor yellow A reduces obesity in mice by modulating the gut microbiota and serum metabolism

Liu, J., Yue, S., Yang, Z., Feng, W., Meng, X., Wang, A., Peng, C. Y., Wang, C., & Yan, D. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.05.012 · Cited by 217 · see citing works

Metformin Affects Gut Microbiome Composition and Function and Circulating Short-Chain Fatty Acids: A Randomized Trial

Mueller, N. T., Differding, M. K., Zhang, M., Maruthur, N. M., Juraschek, S. P., Miller, E. R., Appel, L. J., & Yeh, H. (2021) · Diabetes Care · doi:10.2337/dc20-2257 · Cited by 220 · see citing works

Alterations of the Gut Microbiota in Hashimoto's Thyroiditis Patients

Zhao, F., Feng, J., Li, J., Zhao, L., Liu, Y., Chen, H., Jin, Y., Zhu, B., & Wei, Y. (2018) · Thyroid · doi:10.1089/thy.2017.0395 · Cited by 217 · see citing works

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

Sun, L., Pang, Y., Wang, X., Wu, Q., Liu, H., Liu, B., Liu, C., Ye, M., Kong, W., & Jiang, C. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.02.004 · Cited by 205 · see citing works

MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota

Zhang, X., Ning, Z., Mayne, J., Moore, J. I., Li, J. S. Y., Butcher, J., Deeke, S. A., Chen, R., Chiang, C., Wen, M., et al. (2016) · Microbiome · doi:10.1186/s40168-016-0176-z · Cited by 202 · see citing works

Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice

Wu, M., Yang, S., Wang, S., Cao, Y., Zhao, R., Li, X., Xing, Y., & Liu, L. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00223 · Cited by 201 · see citing works

Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway

Sun, R., Yang, N., Kong, B., Cao, B., Feng, D., Yu, X., Ge, C., Huang, J., Shen, J., Wang, P., et al. (2017) · Molecular Pharmacology · doi:10.1124/mol.116.106617 · Cited by 199 · see citing works

Fecal microbiota transplantation confers beneficial metabolic effects of diet and exercise on diet-induced obese mice

Lai, Z.-L., Tseng, C.-H., Ho, H. J., Cheung, C., Lin, J.-Y., Chen, Y., Cheng, F.-C., Hsu, Y., Lin, J., El-Omar, E. M., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-33893-y · Cited by 192 · see citing works

In vitro digestion and fecal fermentation behaviors of a pectic polysaccharide from okra (Abelmoschus esculentus) and its impacts on human gut microbiota

Wu, D., Nie, X.-R., Gan, R., Guo, H., Fu, Y., Yuan, Q., Zhang, Q. R., & Qin, W. (2020) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2020.106577 · Cited by 193 · see citing works

Balancing Herbal Medicine and Functional Food for Prevention and Treatment of Cardiometabolic Diseases through Modulating Gut Microbiota

Lyu, M., Wang, Y., Fan, G., Wang, X., Xu, S.-Y., & Zhu, Y. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02146 · Cited by 193 · see citing works

Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

Chen, S., Gan, D., Lin, S., Zhong, Y., Chen, M., Zou, X., Shao, Z., & Xiao, G. (2022) · Theranostics · doi:10.7150/thno.71360 · Cited by 197 · see citing works

Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs?

Chen, F., Wen, Q., Jiang, J., Li, H.-L., Tan, Y.-F., Li, Y.-H., & Zeng, N.-K. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.12.031 · Cited by 186 · see citing works

Inulin-type fructan improves diabetic phenotype and gut microbiota profiles in rats

Zhang, Q., Yu, H., Xiao, X., Hu, L.-H., Xin, F.-J., & Yu, X. (2018) · PeerJ · doi:10.7717/peerj.4446 · Cited by 169 · see citing works

In vitro digestion by saliva, simulated gastric and small intestinal juices and fermentation by human fecal microbiota of sulfated polysaccharides from Gracilaria rubra

Di, T., Chen, G., Sun, Y., Ou, S., Zeng, X., & Ye, H. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2017.10.040 · Cited by 181 · see citing works

Probiotic Mixture of Lactobacillus plantarum Strains Improves Lipid Metabolism and Gut Microbiota Structure in High Fat Diet-Fed Mice

Li, H., Liu, F., Lu, J., Shi, J., Guan, J., Yan, F., Li, B., & Huo, G. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00512 · Cited by 182 · see citing works

Effects of Metformin on the Gut Microbiota in Obesity and Type 2 Diabetes Mellitus

Zhang, Q., & Hu, N. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s286430 · Cited by 185 · see citing works

Anti-diabetic Effects of Clostridium butyricum CGMCC0313.1 through Promoting the Growth of Gut Butyrate-producing Bacteria in Type 2 Diabetic Mice

Jia, L., Li, D., Feng, N., Shamoon, M., Sun, Z., Ding, L., Zhang, H., Chen, W., Sun, J., & Chen, Y. Q. (2017) · Scientific Reports · doi:10.1038/s41598-017-07335-0 · Cited by 179 · see citing works

Recent advances in the therapeutic application of short-chain fatty acids (SCFAs): An updated review

Rauf, A., Khalil, A. A., Rahman, U.-U., Khalid, A., Naz, S., Shariati, M. A., Ребезов, М. Б., Zavala, E., de Albuquerque, R. D. D. G., Anwar, S., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1895064 · Cited by 183 · see citing works

Metformin attenuated sepsis-related liver injury by modulating gut microbiota

Liang, H., Song, H., Zhang, X., Song, G., Wang, Y., Ding, X., Duan, X., Li, L., Sun, T., & Kan, Q. (2022) · Emerging Microbes & Infections · doi:10.1080/22221751.2022.2045876 · Cited by 175 · see citing works

Investigation of gut microbiome changes in type 1 diabetic mellitus rats based on high-throughput sequencing

Ma, Q., Li, Y., Wang, J., Li, P., Duan, Y., Dai, H., An, Y., Cheng, L., Wang, T., Wang, C., et al. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.109873 · Cited by 174 · see citing works

Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism

Wang, G., Li, X., Zhao, J., Zhang, H., & Chen, W. (2017) · Food & Function · doi:10.1039/c7fo00593h · Cited by 172 · see citing works

Allobaculum Involves in the Modulation of Intestinal ANGPTLT4 Expression in Mice Treated by High-Fat Diet

Zheng, Z., Lyu, W., Ren, Y., Li, X., Zhao, S., Yang, H., & Xiao, Y. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.690138 · Cited by 171 · see citing works

Grape seed proanthocyanidin extract ameliorates inflammation and adiposity by modulating gut microbiota in high-fat diet mice

Liu, W., Zhao, S., Wang, J., Shi, J., Sun, Y., Wang, W., Ning, G., Hong, J., & Liu, R. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201601082 · Cited by 168 · see citing works

Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier

Hul, M. V., Geurts, L., Plovier, H., Druart, C., Everard, A., Ståhlman, M., Rhimi, M., Chira, K., Teissèdre, P., Delzenne, N. M., et al. (2017) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00107.2017 · Cited by 170 · see citing works

Hypoglycemic and Hypolipidemic Mechanism of Tea Polysaccharides on Type 2 Diabetic Rats via Gut Microbiota and Metabolism Alteration

Li, H., Fang, Q., Nie, Q., Hu, J., Yang, C., Huang, T., Li, H., & Nie, S. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c01968 · Cited by 163 · see citing works

The interaction between the gut Microbiota and herbal medicines

An, X., Bao, Q. D., Di, S., Zhao, Y. C., Zhao, S., Zhang, H., Lian, F., & Tong, X. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109252 · Cited by 166 · see citing works

Therapeutic mechanisms of traditional Chinese medicine to improve metabolic diseases via the gut microbiota

Zhang, H.-Y., Tian, J., Lian, F., Li, M., Liu, W., Zhong, Z., Liao, J., & Tong, X. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110857 · Cited by 163 · see citing works

Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation

Koh, A., Mannerås-Holm, L., Yunn, N.-O., Nilsson, P. M., Ryu, S. H., Molinaro, A., Perkins, R., Smith, J. G., & Bäckhed, F. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.07.012 · Cited by 160 · see citing works

Gut Microbiota Changes and Their Relationship with Inflammation in Patients with Acute and Chronic Insomnia

Li, Y., Zhang, B., Zhou, Y., Wang, D., Liu, X., Li, L., Wang, T., Zhang, Y., Jiang, M., Tang, H., et al. (2020) · Nature and Science of Sleep · doi:10.2147/nss.s271927 · Cited by 159 · see citing works

Polysaccharides from Polygonatum kingianum improve glucose and lipid metabolism in rats fed a high fat diet

Gu, W., Wang, Y., Zeng, L., Dong, J.-C., Bi, Q., Yang, X., Che, Y., He, S., & Yu, J. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.109910 · Cited by 160 · see citing works

High-fiber diet ameliorates gut microbiota, serum metabolism and emotional mood in type 2 diabetes patients

Chen, L., Liu, B., Ren, L., Du, H., Fei, C., Qian, C., Li, B., Zhang, R., Liu, H., Li, Z., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1069954 · Cited by 155 · see citing works

Fucoidan and galactooligosaccharides ameliorate high-fat diet–induced dyslipidemia in rats by modulating the gut microbiota and bile acid metabolism

Chen, Q., Liu, M., Zhang, P., Fan, S., Huang, J., Yu, S., Zhang, C., & Li, H. (2019) · Nutrition · doi:10.1016/j.nut.2019.03.001 · Cited by 157 · see citing works

Beneficial effects of ginger on prevention of obesity through modulation of gut microbiota in mice

Wang, J., Wang, P., Li, D., Hu, X., & Chen, F. (2019) · European Journal of Nutrition · doi:10.1007/s00394-019-01938-1 · Cited by 159 · see citing works

Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota are Attributable to Its Key Ingredient Berberine

Xu, X., Gao, Z., Yang, F., Yang, Y., Chen, L., Lin, H., Zhao, N., Xu, J., Wang, X., Ma, Y., et al. (2020) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2019.09.007 · Cited by 156 · see citing works

Dietary Capsaicin Improves Glucose Homeostasis and Alters the Gut Microbiota in Obese Diabetic ob/ob Mice

Song, J.-X., Ren, H., Gao, Y., Lee, C., Li, S., Zhang, F., Li, L., & Chen, H. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00602 · Cited by 156 · see citing works

Gut microbiota and obesity: An opportunity to alter obesity through faecal microbiota transplant (FMT)

Lee, P. C., Yacyshyn, B., & Yacyshyn, M. B. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13561 · Cited by 153 · see citing works

The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes

Sharma, M., Li, Y., Stoll, M. L., & Tollefsbol, T. O. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2019.01329 · Cited by 152 · see citing works

Considering gut microbiota in treatment of type 2 diabetes mellitus

Adeshirlarijaney, A., & Gewirtz, A. T. (2020) · Gut Microbes · doi:10.1080/19490976.2020.1717719 · Cited by 158 · see citing works

The Relationship between the Gut Microbiome and Metformin as a Key for Treating Type 2 Diabetes Mellitus

Lee, C. B., Chae, S. U., Jo, S. J., Jerng, U. M., & Bae, S. K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073566 · Cited by 149 · see citing works

Modulation of the Gut Microbiota in Rats by Hugan Qingzhi Tablets during the Treatment of High‐Fat‐Diet‐Induced Nonalcoholic Fatty Liver Disease

Tang, W., Yao, X., Xia, F., Yang, M., Chen, Z., Zhou, B., & Liu, Q. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/7261619 · Cited by 148 · see citing works

Activation of a Specific Gut Bacteroides-Folate-Liver Axis Benefits for the Alleviation of Nonalcoholic Hepatic Steatosis

Qiao, S., Li, B., Wang, K., Sun, S., Liao, M., Liu, C., Zhou, N., Ma, K., Zhang, Y., Chen, Y., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108005 · Cited by 147 · see citing works

The polysaccharides from the fruits of Lycium barbarum L. confer anti-diabetic effect by regulating gut microbiota and intestinal barrier

Zhou, W., Yang, T., Xu, W., Huang, Y., Ran, L., Yan, Y., Mi, J., Lu, L., Sun, Y., Zeng, X., et al. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119626 · Cited by 148 · see citing works

The effect of Berberine on weight loss in order to prevent obesity: A systematic review

Ilyas, Z., Perna, S., Al-thawadi, S., Alalwan, T. A., Riva, A., Petrangolini, G., Gasparri, C., Infantino, V., Peroni, G., & Rondanelli, M. (2020) · Biomedicine &amp; Pharmacotherapy · doi:10.1016/j.biopha.2020.110137 · Cited by 143 · see citing works

Dysbiosis signature of mycobiota in colon polyp and colorectal cancer

Gao, R., Kong, C., Li, H., Huang, L., Qu, X., Qin, N., & Qin, H. (2017) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-017-3085-6 · Cited by 144 · see citing works

Anti-diabetic effect of baicalein is associated with the modulation of gut microbiota in streptozotocin and high-fat-diet induced diabetic rats

Zhang, B., Sun, W., Yu, N., Sun, J., Yu, X., Li, X., Xing, Y., Yan, D., Ding, Q., Xiu, Z., et al. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.04.070 · Cited by 139 · see citing works

Huang-Lian-Jie-Du-Decoction Ameliorates Hyperglycemia and Insulin Resistant in Association With Gut Microbiota Modulation

Chen, M., Liao, Z., Lu, B., Wang, M., Lin, L., Zhang, S., Li, Y., Liu, D., Liao, Q., & Xie, Z. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02380 · Cited by 139 · see citing works

Targeting the Intestinal Microbiota to Prevent Type 2 Diabetes and Enhance the Effect of Metformin on Glycaemia: A Randomised Controlled Pilot Study

Palacios, T., Vitetta, L., Coulson, S., Madigan, C. D., Lam, Y. Y., Manuel, R., Briskey, D. R., Hendy, C., Kim, J.-N., Ishoey, T., et al. (2020) · Nutrients · doi:10.3390/nu12072041 · Cited by 139 · see citing works

Effects of Antidiabetic Drugs on Gut Microbiota Composition

Montandon, S., & Jornayvaz, F. (2017) · Genes · doi:10.3390/genes8100250 · Cited by 135 · see citing works

Berberine Modulates Gut Microbiota and Reduces Insulin Resistance via the TLR4 Signaling Pathway

Liu, D., Zhang, Y., Liu, Y., Hou, L.-Q., Li, S., Tian, H., & Zhao, T.-Y. (2018) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0043-125066 · Cited by 136 · see citing works

Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine

Cheng, H., Liu, J., Tan, Y., Feng, W., & Peng, C. Y. (2021) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2021.10.003 · Cited by 137 · see citing works

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

Elbere, I., Kalniņa, I., Silamiķelis, I., Konrāde, I., Zaharenko, L., Sekace, K., Radoviča-Spalviņa, I., Frīdmanis, D., Gudrā, D., Pīrāgs, V., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204317 · Cited by 134 · see citing works

An in vitro model maintaining taxon-specific functional activities of the gut microbiome

Li, L., Abou-Samra, E., Ning, Z., Zhang, X., Mayne, J., Wang, J., Cheng, K., Walker, K., Stintzi, A. P., & Figeys, D. (2019) · Nature Communications · doi:10.1038/s41467-019-12087-8 · Cited by 131 · see citing works

Polygonatum odoratum Polysaccharides Modulate Gut Microbiota and Mitigate Experimentally Induced Obesity in Rats

Wang, Y., Fei, Y., Liu, L., Xiao, Y., Pang, Y., Kang, J., & Wang, Z. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113587 · Cited by 132 · see citing works

Berberine alleviates insulin resistance by reducing peripheral branched-chain amino acids

Yue, S., Liu, J., Wang, A.-T., Meng, X., Yang, Z.-R., Peng, C. Y., Guan, H., Wang, C., & Yan, D. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00256.2018 · Cited by 130 · see citing works

Effects of triphenyl phosphate exposure during fetal development on obesity and metabolic dysfunctions in adult mice: Impaired lipid metabolism and intestinal dysbiosis

Wang, D., Yan, S., Yan, J., Teng, M., Meng, Z., Li, R., Zhou, Z., & Zhu, W. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.12.053 · Cited by 128 · see citing works

Effects of Berberine on the Gastrointestinal Microbiota

Zhang, L., Wu, X., Yang, R., Chen, F., Liao, Y., Zhu, Z., Wu, Z., Sun, X. H., & Wang, L. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.588517 · Cited by 131 · see citing works

Changes in Gut Microbiota and Multiple Sclerosis: A Systematic Review

Ordoñez-Rodriguez, A., Román, P., Rueda‐Ruzafa, L., Campos-Ríos, A., & Cardona, D. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20054624 · Cited by 138 · see citing works

The influence of antibiotics and dietary components on gut microbiota

Dudek-Wicher, R. K., Junka, A., & Bartoszewicz, M. (2018) · Gastroenterology Review · doi:10.5114/pg.2018.76005 · Cited by 126 · see citing works

Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota

Sun, W., Li, X., Dou, H.-Y., Wang, X., Li, J.-D., Shen, L., & Ji, H. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109641 · Cited by 126 · see citing works

Vildagliptin increases butyrate-producing bacteria in the gut of diabetic rats

Zhang, Q., Xiao, X., Li, M., Yu, M., Ping, F., Zheng, J., Wang, T., & Wang, X. (2017) · PLOS ONE · doi:10.1371/journal.pone.0184735 · Cited by 124 · see citing works

Effect of atorvastatin on the gut microbiota of high fat diet-induced hypercholesterolemic rats

Khan, T. J., Ahmed, Y. M., Zamzami, M. A., Mohamed, S. A., Khan, I., Baothman, O. A. S., Mehanna, M. G., & Yasir, M. (2018) · Scientific Reports · doi:10.1038/s41598-017-19013-2 · Cited by 125 · see citing works

Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats

Zhang, X., Zhao, Y., Zhang, M., Pang, X., Xu, J., Kang, C., Li, M., Zhang, C., Zhang, Z., Zhang, Y., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042529 · Cited by 615 · see citing works

Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats. PLoS One 7: e42529

Zhang, X., Zhao, Y., Zhang, M., Pang, X., Xu, J., Kang, C., Li, M., Zhang, C., Zhang, Z., Zhang, Y., et al. (2012)

The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases

Pascale, A., Marchesi, N., Govoni, S. M., Coppola, A., & Gazzaruso, C. (2019) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2019.03.011 · Cited by 240 · see citing works

The effect of berberine on the structure of rats' gut microbiota in vitro

Chao-yin, K. (2013) · Zhongguo weishengtaixue zazhi

Editorial overview: Fibrosis

Borthwick, L. A., & Oakley, F. (2019) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2019.10.003 · Cited by 4 · see citing works