β-aminoisobutyric acid attenuates hepatic endoplasmic reticulum stress and glucose/lipid metabolic disturbance in mice with type 2 diabetes

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Özcan, U., Cao, Q., Yilmaz, E., Lee, A.-H., Iwakoshi, N. N., Özdelen, E., Tuncman, G., Görgün, C., Glimcher, L. H., & Hotamisligil, G. S. (2004) · Science · doi:10.1126/science.1103160 · Cited by 3,844 · see citing works

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Özcan, U., Yilmaz, E., Özcan, L., Furuhashi, M., Vaillancourt, E., Smith, R. O., Görgün, C. Z., & Hotamisligil, G. S. (2006) · Science · doi:10.1126/science.1128294 · Cited by 2,413 · see citing works

Mediators of endoplasmic reticulum stress-induced apoptosis

Szegezdi, E., Logue, S. E., Gorman, A. M., & Samali, A. (2006) · The EMBO Reports · doi:10.1038/sj.embor.7400779 · Cited by 2,345 · see citing works

Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening

Srinivasan, K. K., Viswanad, B., Asrat, L., Kaul, C. L., & Ramarao, P. (2005) · Pharmacological Research · doi:10.1016/j.phrs.2005.05.004 · Cited by 1,879 · see citing works

INHIBITORS OF THE BIOSYNTHESIS AND PROCESSING OF N-LINKED OLIGOSACCHARIDE CHAINS

Elbein, A. D. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.002433 · Cited by 1,126 · see citing works

ER stress and diseases

Yoshida, H. (2007) · The FEBS Journal · doi:10.1111/j.1742-4658.2007.05639.x · Cited by 1,086 · see citing works

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

Zhang, B. B., Zhou, G., & Li, C. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.03.012 · Cited by 1,028 · see citing works

Decoding cell death signals in liver inflammation

Brenner, C., Galluzzi, L., Kepp, O., & Kroemer, G. (2013) · Journal of Hepatology · doi:10.1016/j.jhep.2013.03.033 · Cited by 1,022 · see citing works

The interaction of hepatic lipid and glucose metabolism in liver diseases

Bechmann, L. P., Hannivoort, R. A., Gerken, G., Hotamışlıgil, G. S., Trauner, M., & Canbay, A. E. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2011.08.025 · Cited by 992 · see citing works

From acute ER stress to physiological roles of the Unfolded Protein Response

Wu, J., & Kaufman, R. J. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401840 · Cited by 868 · see citing works

A new rat model of type 2 diabetes: The fat-fed, streptozotocin-treated rat

Reed, M. J., Meszaros, K., Entes, L. J., Claypool, M. D., Pinkett, J. G., Gadbois, T., & Reaven, G. M. (2000) · Metabolism · doi:10.1053/meta.2000.17721 · Cited by 850 · see citing works

The role of mitochondria in apoptosis

Jeong, S., & Seol, D. (2008) · BMB Reports · doi:10.5483/bmbrep.2008.41.1.011 · Cited by 767 · see citing works

Mitochondrial dysfunction in Nash: causes, consequences and possible means to prevent it

Begriche, K., Igoudjil, A., Pessayre, D., & Fromenty, B. (2006) · Mitochondrion · doi:10.1016/j.mito.2005.10.004 · Cited by 753 · see citing works

The Characterization of High‐Fat Diet and Multiple Low‐Dose Streptozotocin Induced Type 2 Diabetes Rat Model

Zhang, M., Lv, X., Li, J., Xu, Z., & Chen, L. (2008) · Journal of Diabetes Research · doi:10.1155/2008/704045 · Cited by 669 · see citing works

β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors

Roberts, L. D., Boström, P., O’Sullivan, J. F., Schinzel, R. T., Lewis, G. D., Dejam, A., Lee, Y.-K., Palma, M. J., Calhoun, S., Georgiadi, A., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.003 · Cited by 643 · see citing works

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

Chaudhari, N., Talwar, P., Parimisetty, A., Lefebvre d’Hellencourt, C., & Ravanan, P. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00213 · Cited by 600 · see citing works

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases

Treiman, M., Caspersen, C. S., & Christensen, S. B. (1998) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(98)01184-5 · Cited by 594 · see citing works

Involvement of Endoplasmic Reticulum Stress in Insulin Resistance and Diabetes

Nakatani, Y., Kaneto, H., Kawamori, D., Yoshiuchi, K., Hatazaki, M., Matsuoka, T., Ozawa, K., Ogawa, S., Hori, M., Yamasaki, Y., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411860200 · Cited by 462 · see citing works

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.

Liu, T.-Y., Shi, C.-X., Gao, R., Sun, H.-J., Xiong, X.-Q., Ding, L., Chen, Q., Li, Y.-H., Wang, J.-J., Kang, Y.-M., et al. (2015) · Clinical science · doi:10.1042/cs20150009 · Cited by 352 · see citing works

Unfolded Protein Response Signaling and Metabolic Diseases

Lee, J., & Özcan, U. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r113.534743 · Cited by 306 · see citing works

Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways

Xiao, F., Huang, Z., Li, H., Yu, J., Wang, C., Chen, S., Meng, Q., Cheng, Y., Gao, X., Li, J., et al. (2011) · Diabetes · doi:10.2337/db10-1246 · Cited by 284 · see citing works

Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo

Dong, Y., Zhang, M., Liang, B., Xie, Z., Zhao, Z., Asfa, S., Choi, H. C., & Zou, M. (2010) · Circulation · doi:10.1161/circulationaha.109.900928 · Cited by 263 · see citing works

FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

Xiong, X.-Q., Chen, D., Sun, H.-J., Ding, L., Wang, J.-J., Chen, Q., Li, Y.-H., Zhou, Y.-B., Han, Y., Zhang, F., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.06.017 · Cited by 242 · see citing works

Targeting endoplasmic reticulum stress in insulin resistance

Salvadó, L., Palomer, X., Barroso, E., & Vázquez‐Carrera, M. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.05.007 · Cited by 215 · see citing works

Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis

Jiang, S., Cheng, Y., Fang, Q., Shao, M., Zhang, Y., Liu, Y., Deng, Y., Shan, B., Liu, J., Li, H., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.565960 · Cited by 183 · see citing works

Association between serum free fatty acid levels and nonalcoholic fatty liver disease: a cross-sectional study

Zhang, J., Zhao, Y. Y., Xu, C., Hong, Y., Lu, H., Wu, J., & Chen, Y. (2014) · Scientific Reports · doi:10.1038/srep05832 · Cited by 172 · see citing works

ER stress: Can the liver cope?

Ji, C., & Kaplowitz, N. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2006.06.004 · Cited by 171 · see citing works

Endoplasmic reticulum stress and endothelial dysfunction

Lenna, S., Han, R., & Trojanowska, M. (2014) · IUBMB Life · doi:10.1002/iub.1292 · Cited by 169 · see citing works

β-AMINO ACIDS: MAMMALIAN METABOLISM AND UTILITY AS α-AMINO ACID ANALOGUES

Griffith, O. W. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.004231 · Cited by 162 · see citing works

BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice

Jung, T. W., Hwang, H.-J., Hong, H. C., Yoo, H. J., Baik, S. H., & Choi, K. M. (2015) · Diabetologia · doi:10.1007/s00125-015-3663-z · Cited by 145 · see citing works

Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β

Ilyas, G., Zhao, E., Liu, K., Lin, Y., Tesfa, L., Tanaka, K. E., & Czaja, M. J. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.08.019 · Cited by 144 · see citing works

Bilirubin Increases Insulin Sensitivity in Leptin-Receptor Deficient and Diet-Induced Obese Mice Through Suppression of ER Stress and Chronic Inflammation

Dong, H., Hu, H., Yun, X., Kim, D., Yue, Y.-N., Wu, H., Sutter, A. G., Chavin, K. D., Otterbein, L. E., Adams, D. B., et al. (2014) · Endocrinology · doi:10.1210/en.2013-1667 · Cited by 130 · see citing works

Glucosamine-Induced Endoplasmic Reticulum Dysfunction Is Associated With Accelerated Atherosclerosis in a Hyperglycemic Mouse Model

Werstuck, G. H., Khan, M. I., Femia, G., Kim, A. J., Tedesco, V. C., Trigatti, B. L., & Shi, Y. (2006) · Diabetes · doi:10.2337/diabetes.55.01.06.db05-0633 · Cited by 124 · see citing works

Topiramate Treatment Protects Blood-Brain Barrier Pericytes from Hyperglycemia-Induced Oxidative Damage in Diabetic Mice

Price, T. O., Eranki, V., Banks, W. A., Nuran Ercal, A., & Shah, G. N. (2011) · Endocrinology · doi:10.1210/en.2011-1638 · Cited by 118 · see citing works

ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress

Wan, X., Lu, X., Xiao, Y.-C., Lin, Y., Zhu, H., Ding, T., Yang, Y., Huang, Y., Zhang, Y., Liu, Y., et al. (2014) · BioMed Research International · doi:10.1155/2014/807874 · Cited by 105 · see citing works

β‐Aminoisobutyric Acid Prevents Diet‐induced Obesity in Mice With Partial Leptin Deficiency

Begriche, K., Massart, J., Abbey‐Toby, A., Igoudjil, A., Lettéron, P., & Fromenty, B. (2008) · Obesity · doi:10.1038/oby.2008.337 · Cited by 99 · see citing works

Aberrant islet unfolded protein response in type 2 diabetes

Engin, F., Nguyen, T., Yermalovich, A. V., & Hotamışlıgil, G. S. (2014) · Scientific Reports · doi:10.1038/srep04054 · Cited by 98 · see citing works

Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity

Fu, S., Yalçın, A., Lee, G. Y., Li, P., Fan, J., Arruda, A. P., Pers, B. M., Yilmaz, M., Eguchi, K., & Hotamışlıgil, G. S. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa9134 · Cited by 97 · see citing works

Glucosamine-Induced Endoplasmic Reticulum Stress Promotes ApoB100 Degradation

Qiu, W., Avramoglu, R. K., Mhapsekar, S., Tsai, J., Austin, R. C., & Adeli, K. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000154142.61859.94 · Cited by 77 · see citing works

Contribution of mitochondria and endoplasmic reticulum dysfunction in insulin resistance: Distinct or interrelated roles?

Rieusset, J. (2015) · Diabetes & Metabolism · doi:10.1016/j.diabet.2015.02.006 · Cited by 68 · see citing works

Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance

Ryu, D., Seo, W., Yoon, Y.-S., Kim, Y.-N., Kim, S. S., Kim, H., Park, T., Choi, C. S., & Koo, S. (2011) · Diabetes · doi:10.2337/db10-1046 · Cited by 61 · see citing works

Inhibition of CYP4A Reduces Hepatic Endoplasmic Reticulum Stress and Features of Diabetes in Mice

Park, E. C., Kim, S. I., Hong, Y., Hwang, J. W., Cho, G.-S., Cha, H.-N., Han, J., Yun, C., Park, S., Jang, I., et al. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.06.039 · Cited by 59 · see citing works

CD47 Deficiency Protects Mice From Diet-induced Obesity and Improves Whole Body Glucose Tolerance and Insulin Sensitivity

Maimaitiyiming, H., Norman‐Burgdolf, H., Zhou, Q., & Wang, S. (2015) · Scientific Reports · doi:10.1038/srep08846 · Cited by 54 · see citing works

Chronic inhibition of cGMP‐specific phosphodiesterase 5 suppresses endoplasmic reticulum stress in heart failure

Gong, W., Duan, Q., Cai, Z., Chen, C., Ni, L., Yan, M., Wang, X., Cianflone, K., & Wang, D. W. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12346 · Cited by 43 · see citing works

Enhanced endoplasmic reticulum stress in bone marrow angiogenic progenitor cells in a mouse model of long-term experimental type 2 diabetes

Bhatta, M., Hongjie, J., Wang, J. J., Sakowski, J. A., & Zhang, S. X. (2015) · Diabetologia · doi:10.1007/s00125-015-3643-3 · Cited by 35 · see citing works

CD38-mediated Ca2+ signaling contributes to glucagon-induced hepatic gluconeogenesis

Rah, S., & Kim, U. (2015) · Scientific Reports · doi:10.1038/srep10741 · Cited by 34 · see citing works

Endoplasmic reticulum stress preconditioning attenuates methylmercury-induced cellular damage by inducing favorable stress responses

Usuki, F., Fujimura, M., & Yamashita, A. (2013) · Scientific Reports · doi:10.1038/srep02346 · Cited by 30 · see citing works

Carbon monoxide-releasing molecules reverse leptin resistance induced by endoplasmic reticulum stress

Zheng, M., Zhang, Q., Joe, Y., Kim, S., Uddin, M. J., Rhew, H., Kim, T., Ryter, S. W., & Chung, H. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00466.2012 · Cited by 30 · see citing works

Doxorubicin-induced apoptosis in H9c2 cardiomyocytes by NF-κB dependent PUMA upregulation.

Li, D., Li, J., An, Y., Yang, Y., & Sq, Z. (2013) · PubMed · Cited by 30 · see citing works

VASP Increases Hepatic Fatty Acid Oxidation by Activating AMPK in Mice

Tateya, S., Rizzo, N. O., Handa, P., Cheng, A. M., Morgan‐Stevenson, V., Ogimoto, K., Kanter, J. E., Bornfeldt, K., Daum, G., Clowes, A. W., et al. (2013) · Diabetes · doi:10.2337/db12-0325 · Cited by 29 · see citing works

C-C Chemokine Receptor 2 Inhibitor Ameliorates Hepatic Steatosis by Improving ER Stress and Inflammation in a Type 2 Diabetic Mouse Model

Kim, H., Lee, E. Y., Lee, B., Yadav, D., Kim, Y. M., Ko, H., Park, K., Lee, E. Y., & Chung, C. H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0120711 · Cited by 25 · see citing works

Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells

Kim, A., Im, M., & Yeul, J. (2015) · Scientific Reports · doi:10.1038/srep08394 · Cited by 15 · see citing works

Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver

Shi, F., Wu, Y., Dai, D., Cong, X., Zhang, Y., & Dai, Y. (2013) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12051 · Cited by 7 · see citing works

Branched Chain Amino Acids

Neinast, M. D., Murashige, D., & Arany, Z. P. (2018) · Annual Review of Physiology · doi:10.1146/annurev-physiol-020518-114455 · Cited by 727 · see citing works

The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review

Gonzalez-Gil, A. M., & Elizondo-Montemayor, L. (2020) · Nutrients · doi:10.3390/nu12061899 · Cited by 278 · see citing works

Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines

Bilski, J., Pierzchalski, P., Szczepanik, M., Bonior, J., & Zoladz, J. A. (2022) · Cells · doi:10.3390/cells11010160 · Cited by 262 · see citing works

Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway

Yan, J., Wang, C., Jin, Y., Meng, Q., Liu, Q., Liu, Z., Liu, K., & Sun, H. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.12.026 · Cited by 248 · see citing works

The role of exercise-induced myokines in regulating metabolism

Huh, J. Y. (2018) · Archives of Pharmacal Research · doi:10.1007/s12272-017-0994-y · Cited by 242 · see citing works

Browning of White Fat: Novel Insight Into Factors, Mechanisms, and Therapeutics: FAT BROWNING AND THEIR POTENTIAL AS THERAPEUTICS

Jeremic, N., Chaturvedi, P., & Tyagi, S. C. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25450 · Cited by 211 · see citing works

β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor

Kitase, Y., Vallejo, J. A., Gutheil, W., Vemula, H., Jähn, K., Yi, J., Zhou, J., Brotto, M., & Bonewald, L. F. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.01.041 · Cited by 219 · see citing works

Myokines mediate the cross talk between skeletal muscle and other organs

Chen, W., Wang, L., You, W., & Shan, T. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30033 · Cited by 162 · see citing works

β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway

Jung, T. W., Park, H. S., Choi, G. H., Kim, D., & Lee, T. (2018) · Journal of Biomedical Science · doi:10.1186/s12929-018-0431-7 · Cited by 137 · see citing works

Myokines in skeletal muscle physiology and metabolism: Recent advances and future perspectives

Das, D. K., Graham, Z. A., & Cardozo, C. P. (2020) · Acta Physiologica · doi:10.1111/apha.13367 · Cited by 129 · see citing works

Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance

Balakrishnan, R., & Thurmond, D. C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094636 · Cited by 132 · see citing works

Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid Metabolism

Tanianskii, D. A., Jarzebska, N., Birkenfeld, A. L., O’Sullivan, J. F., & Rodionov, R. N. (2019) · Nutrients · doi:10.3390/nu11030524 · Cited by 121 · see citing works

White Adipose Tissue Browning: A Double-edged Sword

Abdullahi, A., & Jeschke, M. G. (2016) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2016.06.006 · Cited by 119 · see citing works

Exercise-Induced Myokines can Explain the Importance of Physical Activity in the Elderly: An Overview

Kwon, J. H., Moon, K. M., & Min, K.-W. (2020) · Healthcare · doi:10.3390/healthcare8040378 · Cited by 116 · see citing works

Impact of Lipids on Insulin Resistance: Insights from Human and Animal Studies

Elkanawati, R. Y., Sumiwi, S. A., & Levita, J. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s468147 · Cited by 98 · see citing works

Role of myokines in the development of skeletal muscle insulin resistance and related metabolic defects in type 2 diabetes

Garneau, L., & Aguer, C. (2019) · Diabetes & Metabolism · doi:10.1016/j.diabet.2019.02.006 · Cited by 92 · see citing works

The Role of Exercise, Diet, and Cytokines in Preventing Obesity and Improving Adipose Tissue

ATAKAN, M. M., Koşar, Ş. N., Güzel, Y., Tin, H. T., & Yan, X. (2021) · Nutrients · doi:10.3390/nu13051459 · Cited by 94 · see citing works

Sarcopenic obesity: Myokines as potential diagnostic biomarkers and therapeutic targets?

Guo, A., Li, K., & Xiao, Q. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111022 · Cited by 83 · see citing works

Molecular insights of exercise therapy in disease prevention and treatment

Walzik, D., Chirino, T. Y. W., Zimmer, P., & Joisten, N. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01841-0 · Cited by 89 · see citing works

Role of Physical Activity in Bone–Muscle Crosstalk: Biological Aspects and Clinical Implications

Cariati, I., Bonanni, R., Onorato, F., Mastrogregori, A., Rossi, D., Iundusi, R., Gasbarra, E., Tancredi, V., & Tarantino, U. (2021) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk6020055 · Cited by 76 · see citing works

Bone-Muscle Mutual Interactions

Lara-Castillo, N., & Johnson, M. L. (2020) · Current Osteoporosis Reports · doi:10.1007/s11914-020-00602-6 · Cited by 68 · see citing works

Gut Microbiota Dysbiosis and Its Impact on Type 2 Diabetes: From Pathogenesis to Therapeutic Strategies

Yu, Y., Ding, Y., Wang, S., & Jiang, L. (2025) · Metabolites · doi:10.3390/metabo15060397 · Cited by 67 · see citing works

Myokines and Osteokines in the Pathogenesis of Muscle and Bone Diseases

Colaianni, G., Storlino, G., Sanesi, L., Colucci, S. C., & Grano, M. (2020) · Current Osteoporosis Reports · doi:10.1007/s11914-020-00600-8 · Cited by 61 · see citing works

Myokines: Metabolic regulation in obesity and type 2 diabetes

Chen, Z.-T., Weng, Z.-X., Lin, J. D., & Meng, Z.-X. (2024) · Life Metabolism · doi:10.1093/lifemeta/loae006 · Cited by 58 · see citing works

Metabolomic Determinants of Metabolic Risk in Mexican Adolescents

Perng, W., Hector, E. C., Song, P. X. ‐., Téllez‐Rojo, M. M., Raskind, S., Kachman, M. T., Cantoral, A., Burant, C., & Peterson, K. E. (2017) · Obesity · doi:10.1002/oby.21926 · Cited by 51 · see citing works

Myricitrin Ameliorates Hyperglycemia, Glucose Intolerance, Hepatic Steatosis, and Inflammation in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

Kim, D. Y., Kim, S. R., & Jung, U. J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051870 · Cited by 48 · see citing works

Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway

Lei, Y., Gong, L., Tan, F., Liu, Y., Li, S., Shen, H., Zhu, M. P., Cai, W., Xu, F., Hou, B., et al. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.02.029 · Cited by 45 · see citing works

Branched chain amino acids—friend or foe in the control of energy substrate turnover and insulin sensitivity?

Supruniuk, E., Żebrowska, E., & Chabowski, A. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1977910 · Cited by 46 · see citing works

β-aminoisobutyric acid protects against vascular inflammation through PGC-1β-induced antioxidative properties

Sawada, M., Yamamoto, H., Ogasahara, A., Tanaka, Y., & Kihara, S. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.06.141 · Cited by 44 · see citing works

Ginsenoside Rg5 relieves type 2 diabetes by improving hepatic insulin resistance in db/db mice

Wei, Y., Yang, H., Zhu, C., Deng, J., & Fan, D. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104014 · Cited by 41 · see citing works

β-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibition of renal fibroblast activation and fibrosis

Wang, H., Qian, J., Zhao, X., Xing, C., & Sun, B. (2017) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2016.12.005 · Cited by 38 · see citing works

Signaling metabolite β-aminoisobutyric acid as a metabolic regulator, biomarker, and potential exercise pill

Yi, X., Yang, Y., Li, T., Li, M., Yao, T., Hu, G., Wan, G., & Chang, B. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1192458 · Cited by 36 · see citing works

Glucose metabolism enhancement by 10-hydroxy-2-decenoic acid via the PI3K/AKT signaling pathway in high-fat-diet/streptozotocin induced type 2 diabetic mice

Hu, X., Liu, Z., Lu, Y., Chi, X., Han, K., Wang, H., Wang, Y., Ma, L., & Xu, B. (2022) · Food & Function · doi:10.1039/d1fo03818d · Cited by 36 · see citing works

Salusin‐β Is Involved in Diabetes Mellitus‐Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator‐Activated Receptor Gamma

Sun, H., Chen, D., Wang, P.-Y., Wan, M.-Y., Zhang, C.-X., Zhang, Z.-X., Lin, W., & Zhang, F. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/6905217 · Cited by 35 · see citing works

β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2023) · Molecular Medicine · doi:10.1186/s10020-023-00729-z · Cited by 33 · see citing works

β-aminoisobutyric acid accelerates the proliferation and differentiation of MC3T3-E1 cells via moderate activation of ROS signaling

Zhu, X., Ding, K., Dai, X., & Ling, W. (2018) · Journal of the Chinese Medical Association · doi:10.1016/j.jcma.2017.12.005 · Cited by 33 · see citing works

Urine metabolic fingerprinting can be used to predict the risk of metritis and highlight the pathobiology of the disease in dairy cows

Dervishi, E., Zhang, G., Hailemariam, D., Mandal, R., Wishart, D. S., & Ametaj, B. N. (2018) · Metabolomics · doi:10.1007/s11306-018-1379-z · Cited by 32 · see citing works

Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism

Barlow, J. P., Karstoft, K., Vigelsø, A., Gram, M., Helge, J. W., Dela, F., Pappan, K. L., O’Neil, D. M., Dunn, W. B., & Solomon, T. P. J. (2020) · Metabolism Open · doi:10.1016/j.metop.2020.100053 · Cited by 31 · see citing works

Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits

Yang, Y. R., & Kwon, K. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.602748 · Cited by 32 · see citing works

β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt pathway

Minato, T., Nakamura, N., Saiki, T., Miyabe, M., Ito, M., Matsubara, T., & Naruse, K. (2021) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2021.12.001 · Cited by 32 · see citing works

Pharmacological management of vascular endothelial dysfunction in diabetes: TCM and western medicine compared based on biomarkers and biochemical parameters

Oduro, P. K., Fang, J., Niu, L., Li, Y., Li, L., Zhao, X., & Wang, Q. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104893 · Cited by 31 · see citing works

Analysis of Astragalus Polysaccharide Intervention in Heat-Stressed Dairy Cows’ Serum Metabolomics

Zeng, H., Xi, Y., Li, Y., Wang, Z., Zhang, L., & Han, Z. (2020) · Animals · doi:10.3390/ani10040574 · Cited by 29 · see citing works

The ameliorative effects of thymoquinone and beta-aminoisobutyric acid on streptozotocin-induced diabetic cardiomyopathy

Gür, F. M., & Aktaş, İ. (2021) · Tissue and Cell · doi:10.1016/j.tice.2021.101582 · Cited by 26 · see citing works

Maternal propionate supplementation ameliorates glucose and lipid metabolic disturbance in hypoxia-induced fetal growth restriction

Chen, D., Wang, Y., Li, S.-P., Zhao, H., Jiang, F., Wu, Y., Tong, Y., & Pang, Q. (2022) · Food & Function · doi:10.1039/d2fo01481e · Cited by 26 · see citing works

Exercise-Generated β-Aminoisobutyric Acid (BAIBA) Reduces Cardiomyocyte Metabolic Stress and Apoptosis Caused by Mitochondrial Dysfunction Through the miR-208b/AMPK Pathway

Yu, Y., Chen, W., Yu, M., Liu, J., Sun, H., & Yang, P. C. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.803510 · Cited by 25 · see citing works

BAIBA does not regulate UCP-3 expression in human skeletal muscle as a response to aerobic exercise

Morales, F. E., Forsse, J. S., Andre, T. L., McKinley-Barnard, S. K., Hwang, P. S., Anthony, I. G., Tinsley, G. M., Spillane, M., Grandjean, P. W., Ramirez, A., et al. (2017) · Journal of the American College of Nutrition · doi:10.1080/07315724.2016.1256240 · Cited by 23 · see citing works

Metabolic dysfunction-associated steatotic liver disease and steatohepatitis-associated hepatocarcinoma preclinical models

Leslie, J., Krishnamurthy, K. A., Gopalsamy, I. K., Inácio, P., Huch, M., Gallage, S., Oakley, F., & Vacca, M. (2026) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-025-01162-9 · Cited by 25 · see citing works

Metabokines in the regulation of systemic energy metabolism

MacCannell, A. D. V., & Roberts, L. D. (2022) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2022.102286 · Cited by 23 · see citing works

Myobolites: muscle-derived metabolites with paracrine and systemic effects

Ibrahim, A., Neinast, M., & Arany, Z. P. (2017) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2017.03.007 · Cited by 22 · see citing works

β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes

Audzeyenka, I., Szrejder, M., Rogacka, D., Angielski, S., Saleem, M. A., & Piwkowska, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-27914-8 · Cited by 21 · see citing works

In Vitro Fermentation of Hyaluronan with Different Molecular Weights by Human Gut Microbiota: Differential Effects on Gut Microbiota Structure and Metabolic Function

Zhao, R., Zhang, C., Yu, L., Zhang, C., Zhao, J., Narbad, A., Zhai, Q., & Tian, F. (2023) · Polymers · doi:10.3390/polym15092103 · Cited by 21 · see citing works

Ceragenin CSA13 Reduces Clostridium difficile Infection in Mice by Modulating the Intestinal Microbiome and Metabolites

Wang, J., Ghali, S., Xu, C., Mussatto, C. C., ORTIZ, C. W., Lee, E. C., Tran, D., Jacobs, J. P., Lagishetty, V., Faull, K. F., et al. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.01.026 · Cited by 21 · see citing works

Roles of Amino Acid Derivatives in the Regulation of Obesity

Zheng, J., Xiao, H., Duan, Y., Song, B., Zheng, C., Guo, Q., Li, F., & Li, T. (2021) · Food & Function · doi:10.1039/d1fo00780g · Cited by 20 · see citing works

Bacillus toyonensis SAU-19 Ameliorates Hepatic Insulin Resistance in High-Fat Diet/Streptozocin-Induced Diabetic Mice

Okyere, S. K., Xie, L., Wen, J., Ran, Y., Ren, Z., Deng, J., & Hu, Y. (2021) · Nutrients · doi:10.3390/nu13124512 · Cited by 21 · see citing works

Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Long, X., Liao, S., Wen, P., Zou, Y., Liu, F., Shen, W., & Hu, T. (2020) · Food & Function · doi:10.1039/d0fo00427h · Cited by 19 · see citing works

Safety Assessment of L-β-Aminoisobutyric Acid (L-BAIBA): Subchronic Toxicity Study in Sprague Dawley Rats

Shanmugasundaram, D., Fan, Q., Wang, M., Yi, R., & Wang, O. (2022) · International Journal of Toxicology · doi:10.1177/10915818221094487 · Cited by 18 · see citing works

Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes

Sakamoto, E., Kitase, Y., Fitt, A. J., Zhu, Z., Awad, K. R., Brotto, M. A. P., White, K. E., Welc, S. S., Bergwitz, C., & Bonewald, L. F. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114397 · Cited by 18 · see citing works

Geniposide protects pancreatic β cells from high glucose‐mediated injury by activation of AMP‐activated protein kinase

Liu, C., Hao, Y., Yin, F., Zhang, Y., & Liu, J. (2017) · Cell Biology International · doi:10.1002/cbin.10758 · Cited by 18 · see citing works

KCNH6 protects pancreatic β‐cells from endoplasmic reticulum stress and apoptosis

Lu, J.-K., Shen, H., Li, Q., Xiong, F.-R., Xie, R.-R., Yuan, M.-X., & Yang, J.-K. (2020) · The FASEB Journal · doi:10.1096/fj.202001218r · Cited by 15 · see citing works

L‐BAIBA Synergizes with Sub‐Optimal Mechanical Loading to Promote New Bone Formation

Prideaux, M., Smargiassi, A., Peng, G., Brotto, M. A. P., Robling, A. G., & Bonewald, L. F. (2023) · JBMR Plus · doi:10.1002/jbm4.10746 · Cited by 15 · see citing works

l-β-aminoisobutyric acid, L-BAIBA, a marker of bone mineral density and body mass index, and D-BAIBA of physical performance and age

Lyssikatos, C., Wang, Z., Liu, Z., Warden, S. J., Brotto, M., & Bonewald, L. F. (2023) · Scientific Reports · doi:10.1038/s41598-023-44249-6 · Cited by 15 · see citing works

Bacterial reprogramming of tick metabolism impacts vector fitness and susceptibility to infection

Samaddar, S., Rolandelli, A., O’Neal, A. J., Laukaitis-Yousey, H. J., Marnin, L., Singh, N., Wang, X., Butler, L. R., Rangghran, P., Kitsou, C., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01756-0 · Cited by 14 · see citing works

In vivo and in silico insights into the antidiabetic efficacy of EVOO and hydroxytyrosol in a rat model

Gamal, M., Awad, M. A., Shadidizaji, A., Ibrahim, M. A., Ghoneim, M. A., & Warda, M. (2024) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2024.109775 · Cited by 14 · see citing works

Identification of circulating metabolites associated with wooden breast and white striping

Lake, J. A., Yan, Y., Dekkers, J. C. M., Qiu, J., Brannick, E. M., & Abasht, B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274208 · Cited by 14 · see citing works

Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia

Sharma, A. R., Chatterjee, S., Lee, Y., & Lee, S. (2023) · Aging and Disease · doi:10.14336/ad.2023.00903 · Cited by 15 · see citing works

β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase

Zheng, X., Zhou, L., Jin, Y., Zhao, X., Ahmad, H., Ouyang, Y., Chen, S., Du, J., Chen, X., Chen, L., et al. (2021) · Amino Acids · doi:10.1007/s00726-021-03092-7 · Cited by 12 · see citing works

Opposing effects of clozapine and brexpiprazole on β-aminoisobutyric acid: Pathophysiology of antipsychotics-induced weight gain

Fukuyama, K., Motomura, E., & Okada, M. (2023) · Schizophrenia · doi:10.1038/s41537-023-00336-1 · Cited by 13 · see citing works

Amphiphilic lipid conjugate-mediated surface engineering of placenta-derived mesenchymal stem cells for alleviating liver damage and fibrosis

Kim, S., Lee, D. H., Park, H. W., Noh, K. M., Jangid, A. K., Park, H., Kim, G. J., & Kim, K. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.158313 · Cited by 11 · see citing works

Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood

Izadi, M. S., Eskandari, F., Binayi, F., Salimi, M., Rashidi, F. S., Hedayati, M., Dargahi, L., Ghanbarian, H., & Zardooz, H. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120924 · Cited by 11 · see citing works

Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort

Mirzaei, S., DeVon, H. A., Cantor, R., Cupido, A., Pan, C., Sung, M.-H., Silva, L. F., Hilser, J. R., Hartiala, J., Allayee, H., et al. (2024) · Metabolites · doi:10.3390/metabo14030174 · Cited by 10 · see citing works

Metabolomic Analysis of Follicular Fluid in Normal-Weight Patients with Polycystic Ovary Syndrome

Yu, J., Wei, Y., Zhang, Z., Chen, J., Fu, R., Ye, P., Chen, S., & Yang, J. (2024) · Biomedicines · doi:10.3390/biomedicines12081810 · Cited by 10 · see citing works

Metabolic profiling reveals the heterogeneity of vascular endothelial function phenotypes in individuals at extreme cardiovascular risk

Mao, B., Yi, Y., Mo, Q., Yang, C., & Zhong, Q. (2019) · RSC Advances · doi:10.1039/c9ra05526f · Cited by 10 · see citing works

Investigation of the protective and therapeutic effects of β-aminoisobutyric acid (BAIBA) and Thymoquinone in the diabetic nephropathy

Aktaş, İ., & Gür, F. M. (2021) · Boletin Latinoamericano y del Caribe de plantas Medicinales y Aromaticas · doi:10.37360/blacpma.21.20.3.22 · Cited by 10 · see citing works

Prior Exercise Training Prevent Hyperglycemia in STZ Mice by Increasing Hepatic Glycogen and Mitochondrial Function on Skeletal Muscle

de Carvalho, A. K., da Silva, S., Serafini, E., de Souza, D. R., Farias, H. R., Silveira, G. D. B., Silveira, P. C. L., de Souza, C. T., Portela, L. V., & Muller, A. P. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25658 · Cited by 10 · see citing works

Enhanced L-β-Aminoisobutyric Acid Is Involved in the Pathophysiology of Effectiveness for Treatment-Resistant Schizophrenia and Adverse Reactions of Clozapine

Fukuyama, K., Motomura, E., & Okada, M. (2023) · Biomolecules · doi:10.3390/biom13050862 · Cited by 9 · see citing works

β-Aminoisobutyric Acid Relates to Favorable Glucose Metabolism through Adiponectin in Adults with Obesity Independent of Prediabetes

Faiz, H., Heiston, E. M., & Malin, S. K. (2023) · Journal of Diabetes Research · doi:10.1155/2023/4618215 · Cited by 9 · see citing works

A low-calorie diet raises β-aminoisobutyric acid in relation to glucose regulation and leptin independent of exercise in women with obesity

Faiz, H., & Malin, S. K. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1210567 · Cited by 8 · see citing works

Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review

Yap, K. Y., Chi, H., Ng, S. L., Ng, D. H., & Shelat, V. G. (2023) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v15.i11.2596 · Cited by 8 · see citing works

Fecal Microbiome and Urine Metabolome Profiling of Type 2 Diabetes

Yi, H.-M., Won, S., Pak, J., Park, S.-E., Kim, M.-R., Kim, J.-H., Park, E. Y., Hwang, S., Lee, M., Son, H.-S., et al. (2025) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2411.11071 · Cited by 8 · see citing works

Melphalan induced germ cell toxicity and dose‐dependent effects of β‐aminoisobutyric acid in experimental rat model: Role of oxidative stress, inflammation and apoptosis

Panghal, A., Kumar, V., & Jena, G. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23374 · Cited by 8 · see citing works

A Novel Gliotransmitter, L-β-Aminoisobutyric Acid, Contributes to Pathophysiology of Clinical Efficacies and Adverse Reactions of Clozapine

Fukuyama, K., Motomura, E., & Okada, M. (2023) · Biomolecules · doi:10.3390/biom13091288 · Cited by 8 · see citing works

Dose-Response Absorption Kinetics of Oral L-Beta-Aminoisobutyric Acid (L-BAIBA) Supplementation in Healthy Men and Women

Krieger, J. M., Hagele, A. M., Orr, L. S., Walden, K. E., Gross, K. N., Mumford, P. W., & Kerksick, C. M. (2022) · Journal of Dietary Supplements · doi:10.1080/19390211.2022.2128141 · Cited by 7 · see citing works

L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice

Vallejo, J. A., Kitase, Y., Thiagarajan, G., Dallas, M., Xie, Y., Moore, D. S., Johnson, M. L., Bonewald, L. F., & Wacker, M. (2025) · Aging · doi:10.18632/aging.206325 · Cited by 5 · see citing works

A Candidate Gliotransmitter, L-β-Aminoisobutyrate, Contributes to Weight Gain and Metabolic Complication Induced by Atypical Antipsychotics

Fukuyama, K., Motomura, E., & Okada, M. (2023) · Nutrients · doi:10.3390/nu15071621 · Cited by 5 · see citing works

Protective effects of BAIBA and thymoquinone in type 1 diabetic nephropathy: modulation of Irisin, NF-κB, and Caspase-3 expression

Özöner, M. P., Gür, F. M., Aktaş, İ., Özöner, Ö., & Timurkaan, S. (2026) · Journal of Molecular Histology · doi:10.1007/s10735-026-10719-0 · Cited by 4 · see citing works

Exercise-induced myokines in metabolic regulation: mechanisms, mimetics, and translational potential

Aslam, M. A., Lee, J., Bowen, T. S., & Huh, J. Y. (2026) · Archives of Pharmacal Research · doi:10.1007/s12272-026-01624-x · Cited by 4 · see citing works

β-aminoisobutyric acid ameliorated type 1 diabetes-induced germ cell toxicity in rat: Studies on the role of oxidative stress and IGF-1/AMPK/SIRT-1 signaling pathway

Panghal, A., & Jena, G. (2024) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2024.503820 · Cited by 4 · see citing works

Preparation of β-aminoisobutyric acid and branched chain amino acid-enhanced hydrolysates from chicken breast: Effect of protease types and hydrolysis conditions

Kim, E.-B., Kim, D.-W., Choi, H.-S., Kim, Y., & Kim, M.-K. (2022) · Korean Journal of Food Preservation · doi:10.11002/kjfp.2022.29.2.276 · Cited by 4 · see citing works

Xiasangju alleviates hepatic insulin resistance in db/db mice via AMPK pathway: Mechanisms and active components study

An, Y., Zhao, H., He, C., Shi, L., Su, X., Zhang, H., Huang, Y. Q., Shan, Z., Wang, M., Du, Y., et al. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114675 · Cited by 3 · see citing works

Beta-aminoisobutyric acid attenuates doxorubicin-induced cardiotoxicity through the adenosine 5′-monophosphate-activated protein kinase-mediated pathway

Huang, J., Sun, M., Yu, J. H., Guo, Y., Li, B., Dai, L., Tang, Y., Wang, X., Han, S., & Lai, X. (2025) · Xenobiotica · doi:10.1080/00498254.2025.2520423 · Cited by 1 · see citing works

Lactiplantibacillus plantarum Ln4 attenuates streptozotocin and high-fat diet-induced Type-2 diabetes

Sood, R., Kritika, Sanjay, & Lee, H.-J. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107219 · Cited by 1 · see citing works

The emerging role of the Hippo signaling pathway in interorgan crosstalk

Song, G., Lee, C., & Jho, E. (2026) · The FEBS Journal · doi:10.1111/febs.70587 · Cited by 1 · see citing works

Metabolic small talk during exercise: The role of metabokines and lipokines in interorgan signalling

Gad, S. A., Smith, H., & Roberts, L. D. (2024) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2024.100525 · Cited by 1 · see citing works

Dendrobine inhibits hepatic gluconeogenesis and promotes glycogen synthesis through control of m6A RNA modification of PEPCK/G6Pase by METTL3 in hepatocytes

Chen, S., Zheng, X., Lin, Q., Wang, X., & Liu, Z. (2024) · Epigenetics Insights · doi:10.48130/epi-0024-0004 · Cited by 1 · see citing works

Additional file 3 of β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26649402

Additional file 2 of β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24742978

Additional file 6 of β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26649411

Additional file 7 of β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26649414

Additional file 1 of β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

Zhang, Z., Li, X., Guo, J., He, B., Wu, L., Yang, R., Li, X., Fang, D., Yang, X., Yang, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24741800

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

Laybutt, D. R., Preston, A. M., Åkerfeldt, M. C., Kench, J. G., Busch, A. K., Biankin, A. V., & Biden, T. J. (2007) · Diabetologia · doi:10.1007/s00125-006-0590-z · Cited by 830 · see citing works

Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring

Khater, S. I., Almanaa, T. N., Fattah, D. M. A., Khamis, T., Seif, M. M., Dahran, N. A., Alqahtani, L. S., Metwally, M. M. M., Mostafa, M., Albedair, R. A., et al. (2023) · Antioxidants · doi:10.3390/antiox12061220 · Cited by 40 · see citing works

Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice

Han, M. S., Chung, K. W., Cheon, H. G., Rhee, S. D., Yoon, C., Lee, M., Kim, K., & Lee, M. (2009) · Diabetes · doi:10.2337/db08-0080 · Cited by 117 · see citing works

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients

Marchetti, P., Bugliani, M., Lupi, R., Marselli, L., Masini, M., Boggi, U., Filipponi, F., Weir, G. C., Eizirik, D. L., & Cnop, M. (2007) · Diabetologia · doi:10.1007/s00125-007-0816-8 · Cited by 413 · see citing works

Influence of Bambusa vulgaris leaves extract on Endoplasmic Reticulum Stress Induced by Streptozotocin in Wistar Rats.

Olubodun, B. V., Elekofehinti, O. O., Lawal, A. O., Ajibade, I. W., Sarah, B. A., Tayelolu, M. M., Oluwatosin, F. O., Olowolafe, O. V., & Olawumi, T. S. (2024) · ASEAN Journal of Psychiatry · doi:10.54615/2231-7805.10001117