Cell-penetrating peptides as delivery vehicles for biology and medicine

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Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells

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Arginine-rich Peptides

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Cell-penetrating Peptides

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Transvascular delivery of small interfering RNA to the central nervous system

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Polyarginine enters cells more efficiently than other polycationic homopolymers

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Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent

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A peptide carrier for the delivery of biologically active proteins into mammalian cells

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Clinical biomarkers in drug discovery and development

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Cell-permeable Peptide Antioxidants Targeted to Inner Mitochondrial Membrane inhibit Mitochondrial Swelling, Oxidative Cell Death, and Reperfusion Injury

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TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

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A Comprehensive Model for the Cellular Uptake of Cationic Cell‐penetrating Peptides

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Cell penetration by transportan

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Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

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Cellular Uptake of Unconjugated TAT Peptide Involves Clathrin-dependent Endocytosis and Heparan Sulfate Receptors

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De Novo Antimicrobial Peptides with Low Mammalian Cell Toxicity

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Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

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Transduction peptides: from technology to physiology

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Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes

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Cell-penetrating peptides: tools for intracellular delivery of therapeutics

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Mitochondria-Penetrating Peptides

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Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment

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Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer

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Drug delivery to mitochondria: the key to mitochondrial medicine

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Cell-penetrating peptides and antimicrobial peptides: how different are they?

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The next frontier of molecular medicine: Delivery of therapeutics

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Pathway for Polyarginine Entry into Mammalian Cells

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Lung Delivery Studies Using siRNA Conjugated to TAT(48−60) and Penetratin Reveal Peptide Induced Reduction in Gene Expression and Induction of Innate Immunity

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Cell Penetrating Peptides in Drug Delivery

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Exogenous siRNA delivery using peptide transduction domains/cell penetrating peptides

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Break on through to the Other Side—Biophysics and Cell Biology Shed Light on Cell‐Penetrating Peptides

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Tat Peptide Directs Enhanced Clearance and Hepatic Permeability of Magnetic Nanoparticles

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The Cationic Cell-Penetrating Peptide CPPTAT Derived from the HIV-1 Protein TAT Is Rapidly Transported into Living Fibroblasts: Optical, Biophysical, and Metabolic Evidence

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Self-Assembled Quantum Dot−Peptide Bioconjugates for Selective Intracellular Delivery

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Bak BH3 Peptides Antagonize Bcl-xL Function and Induce Apoptosis through Cytochrome c-independent Activation of Caspases

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A proapoptotic peptide for the treatment of solid tumors.

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In vivo fluorescence imaging for tissue diagnostics

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Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells

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Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells

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Ferrite particles: a superparamagnetic MR contrast agent for the reticuloendothelial system.

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Rapid and effective labeling of brain tissue using TAT-conjugated CdS∶Mn/ZnS quantum dots

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Overcoming methotrexate resistance in breast cancer tumour cells by the use of a new cell-penetrating peptide

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Protection against ischemic brain injury by protein therapeutics

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Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents

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Enhancing the cellular uptake of siRNA duplexes following noncovalent packaging with protein transduction domain peptides

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A Novel Cell-penetrating Peptide, M918, for Efficient Delivery of Proteins and Peptide Nucleic Acids

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Macrocyclic Chelators with Paramagnetic Cations Are Internalized into Mammalian Cells via a HIV-Tat Derived Membrane Translocation Peptide

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Antitumor Effect of a Novel Proapoptotic Peptide that Impairs the Phosphorylation by the Protein Kinase 2 (Casein Kinase 2)

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A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment

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BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore

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Molecular Transporters: Synthesis of Oligoguanidinium Transporters and Their Application to Drug Delivery and Real‐Time Imaging

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Tat-Conjugated Synthetic Macromolecules Facilitate Cytoplasmic Drug Delivery To Human Ovarian Carcinoma Cells

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Arginine magic with new counterions up the sleeve

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Intracellular cargo delivery using tat peptide and derivatives

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The Interaction of Specific Peptide Aptamers With the DNA Binding Domain and the Dimerization Domain of the Transcription Factor Stat3 Inhibits Transactivation and Induces Apoptosis in Tumor Cells

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Multicolor Coding of Cells with Cationic Peptide Coated Quantum Dots

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Uptake and Metabolism of a Dual Fluorochrome Tat-nanoparticle in HeLa Cells

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A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity

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Doxorubicin-peptide conjugates overcome multidrug resistance

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Translocation of β-Galactosidase Mediated by the Cell-Penetrating Peptide Pep-1 into Lipid Vesicles and Human HeLa Cells Is Driven by Membrane Electrostatic Potential

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In vitro characterization of the anticancer activity of membrane-active cationic peptides. I. Peptide-mediated cytotoxicity and peptide-enhanced cytotoxic activity of doxorubicin against wild-type and p-glycoprotein over-expressing tumor cell lines.

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Synthesis of doxorubicin–peptide conjugate with multidrug resistant tumor cell killing activity

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Photoactivation of Quantum Dot Fluorescence Following Endocytosis

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Protamine as an Efficient Membrane-Translocating Peptide

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Selective in Vivo Inhibition of Mitogen-activated Protein Kinase Activation Using Cell-permeable Peptides

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Arginine-Based Molecular Transporters: The Synthesis and Chemical Evaluation of Releasable Taxol-Transporter Conjugates

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Enhanced Targeting and Killing of Tumor Cells Expressing the CXC Chemokine Receptor 4 by Transducible Anticancer Peptides

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Structural Requirements for Cellular Uptake and Antisense Activity of Peptide Nucleic Acids Conjugated with Various Peptides

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Cellular internalization and targeting of semiconductor quantum dots

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Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells

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Controlling Protein Compartmentalization to Overcome Disease

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Inhibition of NF-κB Activation by Peptides Targeting NF-κB Essential Modulator (NEMO) Oligomerization

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Cell-penetrating-peptide-mediated siRNA lung delivery

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Protein Transduction Domain-mediated Delivery of QBP1 Suppresses Polyglutamine-induced Neurodegeneration In Vivo

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Activating FOXO3a, NF-kappaB and p53 by targeting IKKs: An effective multi-faceted targeting of the tumor-cell phenotype?

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Dendritic oligoguanidines as intracellular translocators

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Deconvolution of the Cellular Oxidative Stress Response with Organelle-Specific Peptide Conjugates

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Nuclear Localization Signal-Targeted Poly(ethylene glycol) Conjugates as Potential Carriers and Nuclear Localizing Agents for Carboplatin Analogues

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HeLa Cell Entry by Guanidinium‐Rich β‐Peptides: Importance of Specific Cation–Cell Surface Interactions

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The use of fullerene substituted phenylalanine amino acid as a passport for peptides through cell membranes

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Cellular delivery of a double-stranded oligonucleotide: NFκB decoy by hybridization to complementary PNA linked to a cell-penetrating peptide

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Restoration of p53 function for selective Fas-mediated apoptosis in human and rat glioma cells in vitro and in vivo by a p53 COOH-terminal peptide

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Protamine-Fragment Peptides Fused to an SV40 Nuclear Localization Signal Deliver Oligonucleotides That Produce Antisense Effects in Prostate and Bladder Carcinoma Cells

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HIV-1 Tat Peptide Immunoconjugates Differentially Sensitize Breast Cancer Cells to Selected Antiproliferative Agents That Induce the Cyclin-Dependent Kinase Inhibitor p21WAF-1/CIP-1

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Mitochondria as a therapeutic target for common pathologies

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Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics

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Recent advances in the use of cell-penetrating peptides for medical and biological applications☆

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