Cited by 196Ovarian function and disordersEndometriosis Research and TreatmentReproductive Biology and Fertility

A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines

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Neven, Adriana, Laven, Joop, Teede, Helena, Boyle, Jacqueline·2018·Seminars in Reproductive Medicine

Abstract

Polycystic ovary syndrome (PCOS) is a common hormonal condition with reproductive, metabolic, and psychological sequelae. The Rotterdam Criteria are now internationally accepted, with different phenotypes recognized with varying clinical presentations and risk profiles. The complexity of the disorder, and the impact on quality of life, requires timely diagnosis, screening for complications and management strategies. PCOS remains underdiagnosed and women experience significant delays to diagnosis. Effective dissemination of evidence-based management is therefore vital. In this review, we summarize key aspects of PCOS as a prelude to this issue of Seminars in Reproductive Medicine on PCOS which focuses on the development of the international evidence-based guideline on the assessment and management of PCOS and the related translation program. We cover diagnostic criteria, prevalence, phenotypes, reproductive, metabolic, and psychological factors of PCOS. We also cover management strategies including lifestyle interventions as well as treatment of nonreproductive outcomes and reproductive outcomes informed by the latest international evidence-based guidelines.

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  • Obesity and abdominal obesity have a significant impact on psychosocial status, quality of life, hyperandrogenism, insulin resistance, lipid profiles, ovulation, menstrual cycle, fertility, risks for T2D, and cardiovascular disease onset.

    “Obesity and abdominal obesity have a significant impact on psychosocial status, quality of life, hyperandrogenism, IR, lipid profiles, ovulation, menstrual cycle, fertility, risks for T2D, and cardiovascular disease onset [30, 31].”

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  1. Teede HJ, Misso ML, Costello MF, et al. Norman RJ on behalf of the International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril 2018; In press

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Authors
Neven, A., Laven, J., Teede, H., & Boyle, J.
Affiliations
  • Erasmus MC (NL)
  • Monash University (AU)
  • Monash Medical Centre (AU)
Corresponding author
Boyle, Jacqueline
Venue
Seminars in Reproductive Medicine
Published
2018-01
Volume
36
Issue
01
Pages
005-012
ISSN
  • 1526-4564 (ISSN-L)
  • 1526-8004
OpenAlex
W2891202838
Cited by
196
References
83
Citations by year
2026: 9 · 2025: 22 · 2024: 29 · 2023: 32 · 2022: 43 · 2021: 35 · 2020: 18 · 2019: 8
FWCI
2.30
Type
journal article
Language
en
Open access
Locations
  • Seminars in Reproductive Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Monash University Research Portal (Monash University) (submittedVersion, other-oa)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Funders
National Health and Medical Research Council
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Keywords
polycystic ovary syndrome, Rotterdam criteria, PCOS phenotypes, prevalence, delayed diagnosis, reproductive outcomes, metabolic complications, psychological factors, lifestyle intervention, PCOS management, evidence-based recommendations, quality of life
MeSH terms
Female, Humans, Infertility, Female, Life Style, Polycystic Ovary Syndrome, Prevalence, Symptom Assessment

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