The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Malignant Gliomas in Adults
Abstract
Malignant gliomas, the most common type of primary brain tumor in adults, are associated with disproportionate cancer-related morbidity and mortality. Recently, there have been important advances in our understanding of the molecular pathogenesis of malignant gliomas and progress in treating them. This review summarizes the diagnosis and management of these tumors in adults, highlighting new advances.
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Glioblastoma is associated with mutations in PTEN and amplification of EGFR.
“Glioblastoma is associated with a number of mutations at the genomic level including mutations in the PTEN tumor suppressor and amplification of the gene encoding the epidermal growth factor receptor (EGFR) [3], [4].”
From Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene (2011) · cites this paper as [3]
Citations
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Metadata
- Authors
- Wen, P. Y., & Kesari, S.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2008-07-31
- Volume
- 359
- Issue
- 5
- Pages
- 492-507
- ISSN
- 0028-4793
- 1533-4406
- Cited by
- 3,511
- References
- 12
- Language
- en
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