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Cited by 251Psychosomatic Disorders and Their TreatmentsHeart Rate Variability and Autonomic ControlTactile and Sensory Interactions

The human cortex responds to an interoceptive challenge

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Critchley, Hugo D.·2004·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.0401510101PMC PMC404044
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Abstract

Fast, low-cost, accurate detection of time-resolved dynamic nucleic acid conformational variation in response to small molecule binding: 1) enriches our understanding of nucleic acid structure, and regulation of structure by small molecules as ...Nucleic acids can undergo conformational changes upon binding small molecules. These conformational changes can be exploited to develop new therapeutic strategies through control of gene expression or triggering of cellular responses and can also be used ...

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Crossref · 10.1073/pnas.0401510101

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  • AIC and ACC are commonly coactivated in many experimental tasks and at rest.

    “In line with our meta-analysis on empathy studies, it has been commonly demonstrated that AIC and ACC are coactivated in various experimental paradigms (Critchley, 2004; Dosenbach et al., 2006; Craig, 2009; Medford and Critchley, 2010; Fan et al., 2011) as well as in resting states (Seeley et al., 2007; Britz et al., 2010; Cauda et al., 2011; Fan et al., 2012).”

    From Anterior insular cortex and emotional awareness (2013) · cites this paper as Critchley, 2004

    The Anterior Cingulate Cortex section says ACC activity is enhanced in many challenging tasks, supporting the claim’s breadth of ACC activation. It does not establish common coactivation with anterior insula; the Insula and Context section notes that insula activity did not reach significance in the hypoglycemia study it discusses. The resting-state clause cites other papers, not Critchley (2004). (LLM, conf=0.84)

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  • The insular cortex works closely with a network of regions including ACC, somatosensory cortex, and amygdala.

    “It is noteworthy that the insular cortex works closely with a network of regions, including the ACC (Critchley, 2004; Critchley et al., 2004; Medford and Critchley, 2010; Fan et al., 2011; Denny et al., 2012; Lindquist et al., 2012), somatosensory cortex (Gu et al., 2013), and amygdala (Etkin and Wager, 2007).”

    From Anterior insular cortex and emotional awareness (2013) · cites this paper as Critchley, 2004

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Research works printed but not linked: 23

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Cited by

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Authors
Critchley, H. D.
Affiliations
UCL Queen Square Institute of Neurology (GB)
Corresponding author
Critchley, Hugo D.
ORCID
Critchley, Hugo D.
Venue
Proceedings of the National Academy of Sciences
Publisher
National Academy of Sciences
Published
2004-04-19
Volume
101
Issue
17
Pages
6333-6334
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.0401510101
PMC
PMC404044
OpenAlex
W1988343218
Cited by
251
References
8
Citations by year
2026: 1 · 2025: 8 · 2024: 11 · 2023: 8 · 2022: 14 · 2021: 6 · 2020: 13 · 2019: 9 · 2018: 10 · 2017: 10 · 2016: 11 · 2015: 14 · 2014: 15 · 2013: 14 · 2012: 16
FWCI
7.93
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Keywords
interoception, human cortex, cortical responses, brain activity
MeSH terms
Cerebral Cortex, Humans, Magnetic Resonance Imaging, Tomography, Emission-Computed

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