Extensive Post-translational Modification of Active and Inactivated Forms of Endogenous p53

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Acetylation Is Indispensable for p53 Activation

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Regulation of p53 activity through lysine methylation

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Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2

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The MDM2-p53 interaction.

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p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

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Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.Preprint

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Repression of p53 activity by Smyd2-mediated methylation

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MDM2–HDAC1-mediated deacetylation of p53 is required for its degradation

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Acetylation of p53 inhibits its ubiquitination by Mdm2

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Posttranslational Modification of p53: Cooperative Integrators of FunctionPreprint

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Transcription-independent pro-apoptotic functions of p53

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Arginine methylation regulates the p53 response

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Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

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G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53

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Multiple C-Terminal Lysine Residues Target p53 for Ubiquitin-Proteasome-Mediated Degradation

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Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

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Aurora-A Abrogation of p53 DNA Binding and Transactivation Activity by Phosphorylation of Serine 215

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DNA microarrays identification of primary and secondary target genes regulated by p53

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Latent and active p53 are identical in conformation.

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Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

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E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation

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p53 and Metabolism: Inside the TIGAR

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Surf the Post-translational Modification Network of p53 Regulation

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Basal Dynamics of p53 Reveal Transcriptionally Attenuated Pulses in Cycling Cells

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Analysis of the Adenovirus E1B-55K-Anchored Proteome Reveals Its Link to Ubiquitination Machinery

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Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

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Methylation-Acetylation Interplay Activates p53 in Response to DNA Damage

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Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

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How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?

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Multiple Lysine Mutations in the C-Terminal Domain of p53 Interfere with MDM2-Dependent Protein Degradation and Ubiquitination

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The C-terminal lysines fine-tune p53 stress responses in a mouse model, but are not required for stability control or transactivation

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Aurora B kinase phosphorylates and instigates degradation of p53

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p53 regulation by ubiquitin

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p53 Regulation of Metabolic PathwaysPreprint

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Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

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Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity

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Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self-Assembled Tetramer

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Massively regulated genes: the example of TP53

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Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus

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p53 Acetylation Is Crucial for Its Transcription-independent Proapoptotic Functions

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