Biofilm Formation: A Clinically Relevant Microbiological Process

Donlan, Rodney M.

doi:10.1086/322972

Cited by 1,343Bacterial biofilms and quorum sensingAntifungal resistance and susceptibilityInfection Control in Healthcare

Biofilm Formation: A Clinically Relevant Microbiological Process

Donlan, Rodney M.·2001·Clinical Infectious Diseases

DOI 10.1086/322972

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Abstract

Microorganisms universally attach to surfaces and produce extracellular polysaccharides, resulting in the formation of a biofilm. Biofilms pose a serious problem for public health because of the increased resistance of biofilm-associated organisms to antimicrobial agents and the potential for these organisms to cause infections in patients with indwelling medical devices. An appreciation of the role of biofilms in infection should enhance the clinical decision-making process.

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Authors: Donlan, R. M.
Affiliations: Centers for Disease Control and Prevention (US)
Corresponding author: Donlan, Rodney M.
ORCID: Donlan, Rodney M.
Venue: Clinical Infectious Diseases
Publisher: Oxford University Press (OUP)
Published: 2001-10-15
Volume: 33
Issue: 8
Pages: 1387-1392
ISSN: 1058-4838 (ISSN-L)
1537-6591
DOI: 10.1086/322972
OpenAlex: W2082196711
Cited by: 1,343
References: 38
Citations by year: 2026: 35 · 2025: 61 · 2024: 78 · 2023: 84 · 2022: 93 · 2021: 103 · 2020: 90 · 2019: 79 · 2018: 66 · 2017: 85 · 2016: 72 · 2015: 64 · 2014: 62 · 2013: 56 · 2012: 47
FWCI: 1.19
Type: journal article
Language: en
Open access: closed
Locations: Clinical Infectious Diseases (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
Keywords: biofilm formation, exopolysaccharides, antimicrobial resistance, biofilm-associated infections, indwelling medical devices, device-related infection, clinical decision-making
MeSH terms: Bacteria, Candida albicans, Catheters, Indwelling, Equipment and Supplies, Hospital, Equipment Contamination, Humans, Biofilms

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Biofilm Formation: A Clinically Relevant Microbiological Process

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