The DOI matches its Crossref record; 52 of the 53 references it cites were found in a registry or an index.
Robotic touch shifts perception of embodiment to a prosthesis in targeted reinnervation amputees
Open accessAbstract
Existing prosthetic limbs do not provide amputees with cutaneous feedback. Tactile feedback is essential to intuitive control of a prosthetic limb and it is now clear that the sense of body self-identification is also linked to cutaneous touch. Here we have created an artificial sense of touch for a prosthetic limb by coupling a pressure sensor on the hand through a robotic stimulator to surgically redirected cutaneous sensory nerves (targeted reinnervation) that once served the lost limb. We hypothesize that providing physiologically relevant cutaneous touch feedback may help an amputee incorporate an artificial limb into his or her self image. To investigate this we used a robotic touch interface coupled with a prosthetic limb and tested it with two targeted reinnervation amputees in a series of experiments fashioned after the Rubber Hand Illusion. Results from both subjective (self-reported) and objective (physiological) measures of embodiment (questionnaires, psychophysical temporal order judgements and residual limb temperature measurements) indicate that returning physiologically appropriate cutaneous feedback from a prosthetic limb drives a perceptual shift towards embodiment of the device for these amputees. Measurements provide evidence that the illusion created is vivid. We suggest that this may help amputees to more effectively incorporate an artificial limb into their self image, providing the possibility that a prosthesis becomes not only a tool, but also an integrated body part.
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“Sensory perception is important for control of the prosthetic limb, a sense of embodiment (3), and in the reduction of phantom limb pain (4, 5).”
From A neural interface provides long-term stable natural touch perception (2014) · cites this paper as [3]
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“Embodiment may help amputees think of the prosthesis as a body part rather than just a tool (Marasco et al., 2011).”
From Biomimetic approaches to bionic touch through a peripheral nerve interface (2015) · cites this paper as Marasco et al., 2011
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Cites
Rubber hands ‘feel’ touch that eyes see
Botvinick, M., & Cohen, J. (1998) · Nature · doi:10.1038/35784 · Cited by 4,410
Multiple Comparison Procedures
Hochberg, Y., & Tamhane, A. C. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316672 · Cited by 2,389
Multiple Comparison Procedures
Hahs-Vaughn, D., & Lomax, R. (2013) · Routledge eBooks · doi:10.4324/9780203137819-17 · Cited by 2,132
Brain–machine interfaces: past, present and future
Lebedev, M. A., & Nicolelis, M. A. L. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.07.004 · Cited by 1,875
That's my hand! Activity in premotor cortex reflects feeling of ownership of a limb
Ehrsson, H. H., Spence, C., & Passingham, R. E. (2004) · Science · doi:10.1126/science.1097011 · Cited by 1,348
The rubber hand illusion revisited: visuotactile integration and self-attribution
Tsakiris, M., & Haggard, P. (2005) · Journal of Experimental Psychology: Human Perception and Performance · doi:10.1037/0096-1523.31.1.80 · Cited by 1,328
Travis, W. D., Castile, R. G., Vawter, G. F., Shwachman, H., Warwick, W. J., Burke, B. A., & Skinner, M. M. (1986) · American Journal of Clinical Pathology · doi:10.1093/ajcp/85.4.419 · Cited by 1,189
My body in the brain: A neurocognitive model of body-ownership.
Tsakiris, M. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.09.034 · Cited by 1,069
Projecting sensations to external objects: evidence from skin conductance response
Armel, K. C., & Ramachandran, V. S. (2003) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2003.2364 · Cited by 854
Kuiken, T. A., Dumanian, G. A., Lipschutz, R. D., Miller, L. A., & Stubblefield, K. A. (2004) · Prosthetics & Orthotics International · doi:10.3109/03093640409167756 · Cited by 583
Self-citationDirect neural sensory feedback and control of a prosthetic arm
Dhillon, G. S., & Horch, K. W. (2005) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2005.856072 · Cited by 573
On the other hand: Dummy hands and peripersonal space
Makin, T. R., Holmes, N. P., & Ehrsson, H. H. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.02.041 · Cited by 530
Moseley, G. L., Olthof, N., Venema, A., Don, S., Wijers, M., Gallace, A., & Spence, C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803768105 · Cited by 493
Kuiken, T., Miller, L. A., Lipschutz, R. D., Lock, B. A., Stubblefield, K. A., Marasco, P. D., Zhou, P., & Dumanian, G. A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60193-7 · Cited by 485
Self-citationSpence, C. J., Shore, D. I., & Klein, R. M. (2001) · Journal of Experimental Psychology General · doi:10.1037/0096-3445.130.4.799 · Cited by 477
More than skin deep: Body representation beyond primary somatosensory cortex
Longo, M. R., Azañón, E., & Haggard, P. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.08.022 · Cited by 473
Perceptual Correlates of Massive Cortical Reorganization
Ramachandran, V. S., Rogers-Ramachandran, D., & Stewart, M. (1992) · Science · doi:10.1126/science.1439826 · Cited by 431
Upper limb amputees can be induced to experience a rubber hand as their own
Ehrsson, H. H., Rosén, B., Stockselius, A., Ragnö, C., Kohler, P., & Lundborg, G. (2008) · Brain · doi:10.1093/brain/awn297 · Cited by 350
Perceptual correlates of massive cortical reorganization
Ramachandran, V. S., Stewart, M., & Rogers-Ramachandran, D. (1992) · Neuroreport · doi:10.1097/00001756-199207000-00009 · Cited by 327
Cortical reorganization and phantom phenomena in congenital and traumatic upper-extremity amputees
Flor, H., Elbert, T. R., Mühlnickel, W., Pantev, C., Wienbruch, C., & Taub, E. (1998) · Experimental Brain Research · doi:10.1007/s002210050334 · Cited by 300
Kuiken, T., Marasco, P. D., Lock, B. A., Harden, R. N., & Dewald, J. P. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706525104 · Cited by 284
Self-citationProsthetic usage in major upper extremity amputations
Wright, T. W., Hagen, A. D., & Wood, M. B. (1995) · The Journal Of Hand Surgery · doi:10.1016/s0363-5023(05)80278-3 · Cited by 268
Acute plasticity in the human somatosensory cortex following amputation
Borsook, D., Becerra, L. R., Fishman, S. M., Edwards, A., Jennings, C. L., Stojanovic, M. P., Papinicolas, L., Ramachandran, V. S., González, R. G., & Breiter, H. (1998) · Neuroreport · doi:10.1097/00001756-199804200-00011 · Cited by 229
Decoding a New Neural–Machine Interface for Control of Artificial Limbs
Zhou, P., Lowery, M. M., Englehart, K. B., Huang, H., Li, G., Hargrove, L., Dewald, J. P. A., & Kuiken, T. A. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00178.2007 · Cited by 215
Self-citationNeural Interface Technology for Rehabilitation: Exploiting and Promoting Neuroplasticity
Wang, W., Collinger, J. L., Pérez, M. A., Tyler‐Kabara, E. C., Cohen, L. G., Birbaumer, N., Brose, S. W., Schwartz, A. B., Boninger, M. L., & Weber, D. J. (2009) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2009.07.003 · Cited by 211
Improved Myoelectric Prosthesis Control Accomplished Using Multiple Nerve Transfers
Hijjawi, J. B., Kuiken, T., Lipschutz, R. D., Miller, L. A., Stubblefield, K. A., & Dumanian, G. A. (2006) · Plastic & Reconstructive Surgery · doi:10.1097/01.prs.0000242487.62487.fb · Cited by 157
Self-citationSpatial remapping of touch: Confusion of perceived stimulus order across hand and foot
Heed, T., & Röder, B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601486103 · Cited by 156
Patterson, P. E., & Katz, J. A. (1992) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.1992.01.0001 · Cited by 147
Skin temperature side differences – a diagnostic tool for CRPS?
Wasner, G. L., Schattschneider, J., & Baron, R. (2002) · Pain · doi:10.1016/s0304-3959(01)00470-5 · Cited by 147
Targeted reinnervation for transhumeral amputees: current surgical technique and update on results
Dumanian, G. A., Ko, J. H., O’Shaughnessy, K. D., Kim, P. S., Wilson, C. J., & Kuiken, T. A. (2009) · Plastic and Reconstructive Surgery · doi:10.1097/prs.0b013e3181b038c9 · Cited by 130
Self-citationTargeted Reinnervation to Improve Prosthesis Control in Transhumeral Amputees
O’Shaughnessy, K. D., Dumanian, G. A., Lipschutz, R. D., Miller, L. A., Stubblefield, K. A., & Kuiken, T. (2008) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.g.00268 · Cited by 122
Self-citationVisual enhancement of touch and the bodily self
Longo, M. R., Cardozo, S., & Haggard, P. (2008) · Consciousness and Cognition · doi:10.1016/j.concog.2008.01.001 · Cited by 121
Thermographic imaging of cutaneous sensory segment in patients with peripheral nerve injury
Uematsu, S. (1985) · Journal of neurosurgery · doi:10.3171/jns.1985.62.5.0716 · Cited by 120
The Development of Brain-Machine Interface Neuroprosthetic Devices
Patil, P. G., & Turner, D. A. (2008) · Neurotherapeutics · doi:10.1016/j.nurt.2007.11.002 · Cited by 119
Sensory capacity of reinnervated skin after redirection of amputated upper limb nerves to the chest
Marasco, P. D., Schultz, A. E., & Kuiken, T. A. (2009) · Brain · doi:10.1093/brain/awp082 · Cited by 113
Self-citationValidation of Thermography in the Diagnosis of Reflex Sympathetic Dystrophy
Bruehl, S. P., Lubenow, T. R., Nath, H. A., & Ivankovich, O. (1996) · Clinical Journal of Pain · doi:10.1097/00002508-199612000-00011 · Cited by 109
On the Design of Miniature Haptic Devices for Upper Extremity Prosthetics
Kim, K., Colgate, J. E., Santos-Munné, J. J., Makhlin, A. R., & Peshkin, M. A. (2009) · IEEE/ASME Transactions on Mechatronics · doi:10.1109/tmech.2009.2013944 · Cited by 100
Self-citationSensory-feedback system compatible with myoelectric control
Scott, R. N., Brittain, R. H., Caldwell, R. R., Cameron, A. B., & Dunfield, V. A. (1980) · Medical & Biological Engineering & Computing · doi:10.1007/bf02442481 · Cited by 93
A myoelectrically-controlled prosthesis with sensory feedback
Shannon, G. F. (1979) · Medical & Biological Engineering & Computing · doi:10.1007/bf02440956 · Cited by 92
SENSORY SUBSTITUTION IN PROSTHETICS
Lundborg, G., & Rosén, B. (2001) · Hand Clinics · doi:10.1016/s0749-0712(21)00526-6 · Cited by 81
Murray, C. D. (2007) · Psychoprosthetics · doi:10.1007/978-1-84628-980-4_9 · Cited by 79
Functional Restoration of Adults and Children with Upper Extremity Amputation
Meier, R. H., & Atkins, D. J. (2004) · Medical Entomology and Zoology · Cited by 74
Anani, A. B., Ikeda, K., & Körner, L. M. (1977) · Medical & Biological Engineering & Computing · doi:10.1007/bf02457988 · Cited by 74
Welch, R. B. (1972) · Perception & Psychophysics · doi:10.3758/bf03210933 · Cited by 72
A neural substrate for nonpainful phantom limb phenomena
Flor, H., Mühlnickel, W., Karl, A., Denke, C., Grüsser, S. M., Kurth, R., & Taub, E. (2000) · Neuroreport · doi:10.1097/00001756-200005150-00011 · Cited by 69
Schaefer, M., Nöennig, N., Heinze, H., & Rotte, M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.07.001 · Cited by 65
Schultz, A. E., Marasco, P. D., & Kuiken, T. A. (2009) · Brain Research · doi:10.1016/j.brainres.2008.11.039 · Cited by 58
Self-citationArtificial touch in a hand-prosthesis
Beeker, T. W., During, J., & den Hertog, A. (1967) · Medical & Biological Engineering & Computing · doi:10.1007/bf02478841 · Cited by 55
Feedback in Myoelectric Prostheses
Scott, R. N. (1990) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199007000-00010 · Cited by 46
Sensinger, J. W., Schultz, A. E., & Kuiken, T. (2009) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2009.2032640 · Cited by 38
Self-citationRybarczyk, B. D., & Behel, J. M. (2007) · Springer eBooks · doi:10.1007/978-1-84628-980-4_3 · Cited by 34
Prior, R. E., & Lyman, J. (1975) · PubMed · Cited by 19
Flagged first, then by citations
1 of the 53 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Stark, 2004, Overview of Body-Powered Upper Extremity Prostheses, 175
- Van Dorsten, 2004, Integrating Psychological and Medical Care: Practice Recommendations for Amputation, 73
Cited by
Sorted by citations
Pursuing prosthetic electronic skin
Chortos, A., Liu, J., & Bao, Z. (2016) · Nature Materials · doi:10.1038/nmat4671 · Cited by 2,396
Multisensory brain mechanisms of bodily self-consciousness.
Blanke, O. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3292 · Cited by 1,147
A neural interface provides long-term stable natural touch perception
Tan, D. W., Schiefer, M. A., Keith, M. W., Anderson, J. R., Tyler, J., & Tyler, D. J. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008669 · Cited by 751
Intracortical microstimulation of human somatosensory cortex
Flesher, S. N., Collinger, J. L., Foldes, S. T., Weiss, J. M., Downey, J. E., Tyler-Kabara, E. C., Bensmaia, S. J., Schwartz, A. B., Boninger, M. L., & Gaunt, R. A. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf8083 · Cited by 704
Sensory feedback in upper limb prosthetics
Antfolk, C., D’Alonzo, M., Rosén, B., Lundborg, G., Sebelius, F., & Cipriani, C. (2013) · Expert Review of Medical Devices · doi:10.1586/erd.12.68 · Cited by 466
Metadata
- Authors
- Marasco, P. D., Kim, K., Colgate, J. E., Peshkin, M. A., & Kuiken, T. A.
- Affiliations
- Shirley Ryan AbilityLab (US)
- Northwestern University (US)
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-01-20
- Volume
- 134
- Issue
- 3
- Pages
- 747-758
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- PMC
- PMC3044830
- OpenAlex
- W2121529660
- Cited by
- 335
- References
- 53
- Citations by year
- 2026: 23 · 2025: 8 · 2024: 21 · 2023: 23 · 2022: 22 · 2021: 25 · 2020: 21 · 2019: 24 · 2018: 34 · 2017: 23 · 2016: 18 · 2015: 24 · 2014: 26 · 2013: 17 · 2012: 16
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Brain (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Open Access System for Information Sharing (Pohang University of Science and Technology) (submittedVersion)
- Funders
- Chicago Community Trust
- National Institutes of Health
- Defense Advanced Research Projects Agency (N66001-06-C-8005)
- Advanced Research Projects Agency
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01-HD-4-4798, R01-HD-4-3137, N01-HD-53402)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- amputees, artificial limbs, cutaneous feedback, robotic touch, embodiment, rubber hand illusion, sensory substitution, pressure sensors, temporal order judgment, self-image
- MeSH terms
- Amputation Stumps, Biofeedback, Psychology, Hand, Humans, Illusions, Judgment, Male, Perception, Phantom Limb, Surveys and Questionnaires, Robotics, Sensory Thresholds, Temperature, Touch, Prosthesis Implantation, Young Adult
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