HuR and mRNA stability

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AU-rich elements: characterization and importance in mRNA degradation

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mRNA stability in mammalian cells

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Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

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RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules

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Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

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Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia

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Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

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Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

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Messenger RNA degradation in eukaryotes

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Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

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Regulation of protein kinase cascades by protein phosphatase 2A

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The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism

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RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein

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Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

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Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

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Hypoxic Stabilization of Vascular Endothelial Growth Factor mRNA by the RNA-binding Protein HuR

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INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

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Degradation of mRNA in eukaryotes

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The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.Preprint

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c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

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HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

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Purification, Characterization, and cDNA Cloning of an AU-Rich Element RNA-Binding Protein, AUF1

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HuR Regulates p21 mRNA Stabilization by UV Light

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Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.

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When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

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p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes

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An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

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HNS, a nuclear-cytoplasmic shuttling sequence in HuR

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The yeast exosome and human PM-Scl are related complexes of 3' right-arrow 5' exonucleasesPreprint

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HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

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Control of mRNA Decay by Heat Shock-Ubiquitin-Proteasome Pathway

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Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.

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A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.

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Protein Ligands to Hur Modulate Its Interaction with Target Mrnas in Vivo

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The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

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Glyceraldehyde-3-phosphate Dehydrogenase Selectively Binds AU-rich RNA in the NAD+-binding Region (Rossmann Fold)

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Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

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Stabilization of Interleukin-2 mRNA by the c-Jun NH 2 -Terminal Kinase Pathway

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AUUUA Is Not Sufficient To Promote Poly(A) Shortening and Degradation of an mRNA: the Functional Sequence within AU-Rich Elements May Be UUAUUUA(U/A)(U/A)

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HuR binding to cytoplasmic mRNA is perturbed by heat shock

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Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

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A conserved family of elav-like genes in vertebrates.

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Identification of HuR as a protein implicated in AUUUA‐mediated mRNA decay

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Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

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An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

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The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.Preprint

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Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

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RNA binding specificity of hnRNP proteins: a subset bind to the 3′ end of introns.

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Identification of TIAR as a Protein Binding to the Translational Regulatory AU-rich Element of Tumor Necrosis Factor α mRNA

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ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation systemPreprint

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The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes

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Sequential expression and role of Hu RNA-binding proteins during neurogenesis

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A Signaling Complex of Ca 2+ -Calmodulin-Dependent Protein Kinase IV and Protein Phosphatase 2A

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Embryonic Lethal Abnormal Visual RNA-Binding Proteins Involved in Growth, Differentiation, and Posttranscriptional Gene Expression

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Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease

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Relationship between Σ3 Boundaries, Dislocation Slip, and Plasticity in Pure Nickel.

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The Exosome

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Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast

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The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA

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Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.

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ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cellsPreprint

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Rat1p and Xrn1p Are Functionally Interchangeable Exoribonucleases That Are Restricted to and Required in the Nucleus and Cytoplasm, Respectively

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Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes

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The Yeast Pan2 Protein Is Required for Poly(A)-binding Protein-stimulated Poly(A)-nuclease Activity

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Detection and Characterization of a 3′ Untranslated Region Ribonucleoprotein Complex Associated with Human α-Globin mRNA Stability

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Cap‐dependent deadenylation of mRNA

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Interaction between a Poly(A)-Specific Ribonuclease and the 5′ Cap Influences mRNA Deadenylation Rates In Vitro

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A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

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Molecular Identification of I1PP2A, a Novel Potent Heat-Stable Inhibitor Protein of Protein Phosphatase 2A

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PAN3 Encodes a Subunit of the Pab1p-Dependent Poly(A) Nuclease in Saccharomyces cerevisiae

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Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization.

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Regulation of mRNA turnover in eukaryotic cells.

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AU RNA-binding factors differ in their binding specificities and affinities.

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Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells.

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c‐jun N‐terminal kinase is involved in AUUUA‐mediated interleukin‐3 mRNA turnover in mast cells

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The Elav-like Proteins Bind to a Conserved Regulatory Element in the 3′-Untranslated Region of GAP-43 mRNA

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Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast.

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Cytoplasmic localization is required for the mammalian ELAV‐like protein HuD to induce neuronal differentiation

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12-O-Tetradecanoylphorbol-13-acetate-induced Dephosphorylation of Protein Kinase Cα Correlates with the Presence of a Membrane-associated Protein Phosphatase 2A Heterotrimer

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Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA

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p53-Dependent Elevation of p21 Waf1 Expression by UV Light Is Mediated through mRNA Stabilization and Involves a Vanadate-Sensitive Regulatory System

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Template activating factor I, a novel host factor required to stimulate the adenovirus core DNA replication

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Making sense of nonsense in yeast

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AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradationPreprint

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