Elderly men and women benefit equally from prolonged resistance-type exercise training
Open accessAbstract
This study compares the effects of 6 months resistance-type exercise training (three times per week) between healthy elderly women (n = 24; 71±1 years) and men (n = 29; 70±1 years). Muscle mass (dual-energy x-ray absorptiometry-computed tomography), strength (one-repetition maximum), functional capacity (sit-to-stand time), muscle fiber characteristics (muscle biopsies), and metabolic profile (blood samples) were assessed. Leg lean mass (3% ± 1%) and quadriceps cross-sectional area (9% ± 1%) increased similarly in both groups. One-repetition maximum leg extension strength increased by 42% ± 3% (women) and 43% ± 3% (men). Following training, type II muscle fiber size had increased, and a type II muscle fiber specific increase in myonuclear and satellite cell content was observed with no differences between genders. Sit-to-stand time decreased similarly in both groups. Glycemic control and blood lipid profiles improved to a similar extent in both women and men. A generic resistance-type exercise training program can be applied for both women and men to effectively counteract the loss of muscle mass and strength with aging.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The incorporation of high-velocity contractions in power training (PT) may have played a key role in counteracting muscle loss associated with aging and obesity.
“The incorporation of high-velocity contractions in PT may have played a key role in counteracting muscle loss associated with aging and obesity [32,33].”
From Efficacy of Power Training on Sarcopenic Obesity in Community-Dwelling Older Women: A 32-Week Randomized Clinical Trial (2025) · cites this paper as [32]
The Skeletal Muscle Hypertrophy section reports increased quadriceps muscle size after resistance training in older adults, supporting the general point that training can counter age-related muscle loss. The exercise intervention section describes resistance training but does not identify high-velocity contractions or power training, and the paper does not establish that such contractions counteract muscle loss associated with obesity. Page numbers were not available in our copy. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc11-s062 · Cited by 14,019 · see citing works
Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.2.m85 · Cited by 9,792 · see citing works
Compendium of physical activities: an update of activity codes and MET intensities
AINSWORTH, B. E., HASKELL, W. L., WHITT, M. C., IRWIN, M. L., SWARTZ, A. M., STRATH, S. J., O???BRIEN, W. L., BASSETT, D. R., SCHMITZ, K. H., EMPLAINCOURT, P. O., et al. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200009001-00009 · Cited by 8,497 · see citing works
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
Vermeulen, A., Verdonck, L., & Kaufman, J. M. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6079 · Cited by 3,824 · see citing works
Exercise training and nutritional supplementation for physical frailty in very elderly people
Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857 · see citing works
Sarcopenia: origins and clinical relevance
Rosenberg, I. H. (1997) · The Journal of Nutrition · doi:10.1093/jn/127.5.990s · Cited by 2,399 · see citing works
What is the cause of the ageing atrophy?
Lexell, J. E., Taylor, C. C., & Sjöstróm, M. (1988) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(88)90132-3 · Cited by 2,080 · see citing works
Invited Review: Aging and sarcopenia
Doherty, T. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00347.2003 · Cited by 1,764 · see citing works
High-Intensity Strength Training in Nonagenarians: Effects on Skeletal Muscle
Fiatarone, M. A. (1990) · JAMA · doi:10.1001/jama.1990.03440220053029 · Cited by 1,593 · see citing works
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446 · see citing works
Strength conditioning in older men: skeletal muscle hypertrophy and improved function
Frontera, W. R., Meredith, C. N., O'Reilly, K. P., Knuttgen, H. G., & Evans, W. J. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.64.3.1038 · Cited by 1,386 · see citing works
Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research
Bergström, J. P. (1975) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365517509095787 · Cited by 1,159 · see citing works
Age and gender comparisons of muscle strength in 654 women and men aged 20–93 yr
Lindle, R. S., Metter, E. J., Lynch, N. A., Fleg, J. L., Fozard, J. L., Tobin, J. D., Roy, T. A., & Hurley, B. F. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.5.1581 · Cited by 971 · see citing works
Goodpaster, B. H., Kelley, D. E., Thaete, F. L., He, J., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.104 · Cited by 956 · see citing works
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2006) · Diabetes Care · doi:10.2337/diacare.29.s1.06.s43 · Cited by 924 · see citing works
Katz, S., Branch, L. G., Branson, M. H., Papsidero, J. A., Beck, J. C., & Greer, D. S. (1983) · New England Journal of Medicine · doi:10.1056/nejm198311173092005 · Cited by 808 · see citing works
Sarcopenia: origins and clinical relevance
Rosenberg, I. H. (2011) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2011.03.003 · Cited by 786 · see citing works
Häkkinen, K., Kallinen, M., Izquierdo, M., Jokelainen, K., Lassila, H., Mälkiä, E., Kraemer, W. J., Newton, R. U., & Alen, M. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.84.4.1341 · Cited by 776 · see citing works
Decreased Muscle Strength and Quality in Older Adults With Type 2 Diabetes
Park, S. W., Goodpaster, B. H., Strotmeyer, E. S., de Rekeneire, N., Harris, T. B., Schwartz, A. V., Tylavsky, F. A., & Newman, A. B. (2006) · Diabetes · doi:10.2337/db05-1183 · Cited by 751 · see citing works
Adult lean body mass declines with age: Some longitudinal observations
Forbes, G. B., & Reina, J. C. (1970) · Metabolism · doi:10.1016/0026-0495(70)90062-4 · Cited by 684 · see citing works
Tieland, M., Dirks, M. L., van der Zwaluw, N., Verdijk, L. B., van de Rest, O., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.05.020 · Cited by 556 · see citing works
Self-citationKosek, D. J., Kim, J.-S., Petrella, J. K., Cross, J. M., & Bamman, M. M. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01474.2005 · Cited by 503 · see citing works
Larsson, L., Sjödin, B., & Karlsson, J. (1978) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1978.tb06187.x · Cited by 498 · see citing works
Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly
Verdijk, L. B., Koopman, R., Schaart, G., Meijer, K., Savelberg, H. H. C. M., & van Loon, L. J. C. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00278.2006 · Cited by 489 · see citing works
Self-citationMuscle hypertrophy response to resistance training in older women
Charette, S. L., McEvoy, L., Pyka, G., Snow-Harter, C., Guido, D., WISWELL, R. A., & Marcus, R. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.70.5.1912 · Cited by 483 · see citing works
Effects of heavy-resistance training on hormonal response patterns in younger vs. older men
Kraemer, W. J., Häkkinen, K., Newton, R. U., Nindl, B. C., Volek, J. S., McCormick, M., Gotshalk, L. A., Gordon, S. E., Fleck, S. J., Campbell, W. W., et al. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.3.982 · Cited by 467 · see citing works
Tieland, M., van de Rest, O., Dirks, M. L., van der Zwaluw, N., Mensink, M., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.005 · Cited by 446 · see citing works
Jones, P. R., & PEARSON, J. S. (1969) · PubMed · Cited by 429 · see citing works
Verdijk, L. B., Gleeson, B. G., Jonkers, R. A. M., Meijer, K., Savelberg, H. H. C. M., Dendale, P., & van Loon, L. J. C. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gln050 · Cited by 372 · see citing works
Self-citationMuscle quality. II. Effects of strength training in 65- to 75-yr-old men and women
Tracy, B. L., Ivey, F. M., Hurlbut, D., Martel, G. F., Lemmer, J. T., Siegel, E. L., Metter, E. J., Fozard, J. L., Fleg, J. L., & Hurley, B. F. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.86.1.195 · Cited by 371 · see citing works
Häkkinen, K., Pakarinen, A., Kraemer, W. J., HÄKKINEN, A. H., Valkeinen, H., & Alén, M. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.2.569 · Cited by 368 · see citing works
Functional consequences of sarcopenia and dynapenia in the elderly
Clark, B. C., & Manini, T. M. (2010) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e328337819e · Cited by 359 · see citing works
Functional and Metabolic Consequences of Sarcopenia
Vandervoort, A. A., & Symons, T. B. (2001) · Canadian Journal of Applied Physiology · doi:10.1139/h01-007 · Cited by 324 · see citing works
Ferri, A., Scaglioni, G., Pousson, M., Capodaglio, P., Hoecke, J. V., & Narici, M. V. (2002) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01050.x · Cited by 306 · see citing works
Resistance Exercise and Physical Performance in Adults Aged 60 to 83
Vincent, K. R., Braith, R. W., Feldman, R. A., Magyari, P. M., Cutler, R. B., Persin, S. A., Lennon, S. L., Gabr, A., & Lowenthal, D. T. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50267.x · Cited by 294 · see citing works
West, D. W. D., Burd, N. A., Tang, J. E., Moore, D. R., Staples, A. W., Holwerda, A. M., Baker, S. K., & Phillips, S. M. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01147.2009 · Cited by 290 · cited 1× · see citing works
“These findings lend support to the assumption that hormonal profile may not be as important in the general response to resistance-type exercise training as was previously assumed (61,62).”
ResultWest, D. W. D., Kujbida, G. W., Moore, D. R., Atherton, P., Burd, N. A., Padzik, J. P., De Lisio, M., Tang, J. E., Parise, G., Rennie, M. J., et al. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.177220 · Cited by 289 · see citing works
Age and gender responses to strength training and detraining
Lemmer, J. T., HURLBUT, D. E., Martel, G. F., Tracy, B. L., EY, F. M., Metter, E. J., Fozard, J. L., Fleg, J. L., & Hurley, B. F. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200008000-00021 · Cited by 288 · see citing works
Ivey, F. M., Roth, S. M., Ferrell, R. E., Tracy, B. L., Lemmer, J. T., Hurlbut, D. E., Martel, G. F., Siegel, E. L., Fozard, J. L., Metter, E. J., et al. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.11.m641 · Cited by 288 · see citing works
Muscle fiber size and function in elderly humans: a longitudinal study
Frontera, W. R., Reid, K. F., Phillips, E. M., Krivickas, L. S., HUGHES, V. A., Roubenoff, R., & Fielding, R. A. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90332.2008 · Cited by 285 · see citing works
Strength training increases insulin action in healthy 50- to 65-yr-old men
Miller, J. P., Pratley, R. E., Goldberg, A. P., Gordon, P., Rubin, M., Treuth, M. S., Ryan, A. S., & Hurley, B. F. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.3.1122 · Cited by 282 · see citing works
Effect of resistance training on single muscle fiber contractile function in older men
Trappe, S. W., Williamson, D., Godard, M. P., Porter, D. A., Rowden, G., & COSTILL, D. L. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.143 · Cited by 270 · see citing works
Verdijk, L. B., Jonkers, R. A., Gleeson, B. G., Beelen, M., Meijer, K., Savelberg, H. H., Wodzig, W. K., Dendale, P., & van Loon, L. J. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26626 · Cited by 253 · see citing works
Self-citationEffects of Strength Training and Detraining on Muscle Quality: Age and Gender Comparisons
Ivey, F. M., Tracy, B. L., Lemmer, J. T., NessAiver, M., Metter, E. J., Fozard, J. L., & Hurley, B. F. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.3.b152 · Cited by 247 · see citing works
Effect of Age on Muscle Hypertrophy Induced by Resistance Training
Welle, S. L., Totterman, S. M. S., & Thornton, C. (1996) · The Journals of Gerontology Series A · doi:10.1093/gerona/51a.6.m270 · Cited by 247 · see citing works
One-repetition maximum strength test represents a valid means to assess leg strengthin vivoin humans
Verdijk, L. B., van Loon, L. J. C., Meijer, K., & Savelberg, H. H. C. M. (2008) · Journal of Sports Sciences · doi:10.1080/02640410802428089 · Cited by 222 · see citing works
Self-citationFunctional and Metabolic Consequences of Sarcopenia
Evans, W. J. (1997) · Journal of Nutrition · doi:10.1093/jn/127.5.998s · Cited by 220 · see citing works
Muscular endurance repetitions to predict bench press strength in men of different training levels.
Mayhew, J. L., Prinster, J. L., Ware, J. S., Zimmer, D. L., Arabas, J. R., & Bemben, M. G. (1995) · PubMed · Cited by 210 · see citing works
Association of IGF-I levels with muscle strength and mobility in older women
Cappola, A. R., Bandeen-Roche, K., Wand, G. S., Volpato, S., & Fried, L. P. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7868 · Cited by 205 · see citing works
Gender Differences in Resistance-Training-Induced Myofiber Hypertrophy Among Older Adults
Bamman, M. M., Hill, V. J., Adams, G. R., Haddad, F., Wetzstein, C. J., Gower, B. A., Ahmed, A., & Hunter, G. R. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.2.b108 · Cited by 199 · see citing works
Resistance training improves single muscle fiber contractile function in older women
Trappe, S. W., Godard, M. P., Gallagher, P. M., Carroll, C. C., Rowden, G., & Porter, D. A. (2001) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2001.281.2.c398 · Cited by 189 · see citing works
Lexell, J. E., Downham, D. Y., Larsson, Y., Bruhn, E., & Morsing, B. (1995) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.1995.tb00055.x · Cited by 169 · see citing works
Muscle Size Responses to Strength Training in Young and Older Men and Women
Roth, S. M., Ivey, F. M., Martel, G. F., Lemmer, J. T., HURLBUT, D. E., Siegel, E. L., Metter, E. J., Fleg, J. L., Fozard, J. L., Kostek, M. C., et al. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.4911233.x · Cited by 167 · see citing works
Age and sex affect human muscle fibre adaptations to heavy-resistance strength training
Martel, G. F., Roth, S. M., Ivey, F. M., Lemmer, J. T., Tracy, B. L., Hurlbut, D. E., Metter, E. J., Hurley, B. F., & Rogers, M. A. (2006) · Experimental Physiology · doi:10.1113/expphysiol.2005.032771 · Cited by 149 · see citing works
Protein Supplementation during Resistance-Type Exercise Training in the Elderly
Leenders, M., Verdijk, L. B., van der Hoeven, L., van Kranenburg, J. M. X., Nilwik, R., Wodzig, W. K. W. H., Senden, J. M., KEIZER, H. A., & van Loon, L. J. C. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318272fcdb · Cited by 129 · see citing works
Self-citationStrength training in older women: Early and late changes in whole muscle and single cells
Frontera, W. R., HUGHES, V. A., Krivickas, L. S., Kim, S., Foldvari, M., & Roubenoff, R. (2003) · Muscle & Nerve · doi:10.1002/mus.10480 · Cited by 120 · see citing works
The journal of nutrition, health & aging
(2024) · The journal of nutrition health & aging · doi:10.1007/12603.1760-4788 · Cited by 118 · see citing works
Capodaglio, P., Capodaglio, E. M., Facioli, M., & Saibene, F. (2006) · European Journal of Applied Physiology · doi:10.1007/s00421-006-0195-8 · Cited by 107 · see citing works
Effects of aerobic and strength-based training on metabolic health indicators in older adults
Martins, R. A., Veríssimo, M. T., Coelho-e-Silva, M. J., Cumming, S. P., & Teixeira, A. M. (2010) · Lipids in Health and Disease · doi:10.1186/1476-511x-9-76 · Cited by 107 · see citing works
Resistive Training Increases Insulin Action in Postmenopausal Women
Ryan, A. S., Pratley, R., Goldberg, A. P., & Elahi, D. (1996) · The Journals of Gerontology Series A · doi:10.1093/gerona/51a.5.m199 · Cited by 104 · see citing works
Strandberg, S., Wretling, M.-L., Wredmark, T., & Shalabi, A. (2010) · BMC Medical Imaging · doi:10.1186/1471-2342-10-18 · Cited by 100 · see citing works
Chevalier, S., Saoud, F., Gray‐Donald, K., & Morais, J. A. (2008) · The journal of nutrition health & aging · doi:10.1007/bf03028620 · Cited by 90 · see citing works
Oral amino-acid provision does not affect muscle strength or size gains in older men
Godard, M. P., WILLIAMSON, D. L., & Trappe, S. W. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200207000-00012 · Cited by 76 · see citing works
Association of IGF-I Levels with Muscle Strength and Mobility in Older Women
Cappola, A. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.9.4139 · Cited by 50 · see citing works
Zhang, X., Geiss, L. S., Caspersen, C. J., Cheng, Y. J., Engelgau, M. M., Johnson, J. A., Plotnikoff, R. C., & Gregg, E. W. (2010) · Preventive Medicine · doi:10.1016/j.ypmed.2010.02.015 · Cited by 22 · see citing works
DiPietro, L., Yeckel, C. W., & Dziura, J. (2008) · Journal of Physical Activity and Health · doi:10.1123/jpah.5.6.854 · Cited by 16 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Nilwik, R., Snijders, T., Leenders, M., Groen, B. B. L., van Kranenburg, J., Verdijk, L. B., & van Loon, L. J. C. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.02.012 · Cited by 776 · see citing works
Self-citationExercise Attenuates the Major Hallmarks of Aging
Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015) · Rejuvenation Research · doi:10.1089/rej.2014.1623 · Cited by 413 · see citing works
Dirks, M. L., Wall, B. T., van de Valk, B., Holloway, T. M., Holloway, G. P., Chabowski, A., Goossens, G. H., & van Loon, L. J. C. (2016) · Diabetes · doi:10.2337/db15-1661 · Cited by 391 · see citing works
Fatty infiltration of skeletal muscle: mechanisms and comparisons with bone marrow adiposity
Hamrick, M. W., McGee-Lawrence, M. E., & Frechette, D. M. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00069 · Cited by 372 · see citing works
Chen, H., Chung, Y., Chen, Y., Ho, S., & Wu, H. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14722 · Cited by 317 · see citing works
Lifelong physical exercise delays age-associated skeletal muscle decline
Zampieri, S., Pietrangelo, L., Loefler, S., Fruhmann, H., Vogelauer, M., Burggraf, S., Pond, A., Grim-Stieger, M., Cvecka, J., Sedliak, M., et al. (2015) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu006 · Cited by 282 · see citing works
Live strong and prosper: the importance of skeletal muscle strength for healthy ageing
McLeod, M., Breen, L., Hamilton, D. L., & Philp, A. (2016) · Biogerontology · doi:10.1007/s10522-015-9631-7 · Cited by 274 · see citing works
Creatine supplementation during resistance training in older adults - a meta-analysis
DEVRIES, M. C., & PHILLIPS, S. M. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000220 · Cited by 239 · see citing works
Da Boit, M., Sibson, R., Sivasubramaniam, S., Meakin, J. R., Greig, C. A., Aspden, R. M., Thies, F., Jeromson, S., Hamilton, D. L., Speakman, J. R., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.140780 · Cited by 185 · see citing works
Snijders, T., Res, P. T., Smeets, J. S., van Vliet, S., van Kranenburg, J., Maase, K., Kies, A. K., Verdijk, L. B., & van Loon, L. J. (2015) · The Journal of Nutrition · doi:10.3945/jn.114.208371 · Cited by 175 · see citing works
Self-citationProtein and exercise in the prevention of sarcopenia and aging
Naseeb, M. A., & Volpe, S. L. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.01.001 · Cited by 160 · see citing works
Nutritional Supplements in Support of Resistance Exercise to Counter Age-Related Sarcopenia
Phillips, S. M. (2015) · Advances in Nutrition · doi:10.3945/an.115.008367 · Cited by 144 · see citing works
Holloway, G. P., Holwerda, A. M., Miotto, P. M., Dirks, M. L., Verdijk, L. B., & van Loon, L. J. C. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.02.069 · Cited by 134 · see citing works
Self-citationMuscle wasting and aging: Experimental models, fatty infiltrations, and prevention
Brioche, T., Pagano, A. F., Py, G., & Chopard, A. (2016) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2016.04.006 · Cited by 129 · see citing works
Devries, M. C., Breen, L., Von Allmen, M., MacDonald, M. J., Moore, D. R., Offord, E. A., Horcajada, M.-N., Breuillé, D., & Phillips, S. M. (2015) · Physiological Reports · doi:10.14814/phy2.12493 · Cited by 107 · see citing works
Home-based resistance training for older adults: a systematic review.
Thiebaud, R. S., Funk, M. D., & Abe, T. (2014) · Geriatrics & Gerontology International · doi:10.1111/ggi.12326 · Cited by 105 · see citing works
Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration
Tachtsis, B., Camera, D., & Lacham-Kaplan, O. (2018) · Nutrients · doi:10.3390/nu10030309 · Cited by 104 · see citing works
Jones, M. D., Wewege, M. A., Hackett, D. A., Keogh, J. W. L., & Hagstrom, A. D. (2021) · Sports Medicine · doi:10.1007/s40279-020-01388-4 · Cited by 96 · see citing works
Growing older with health and vitality: a nexus of physical activity, exercise and nutrition
Witard, O. C., McGlory, C., Hamilton, D. L., & Phillips, S. M. (2016) · Biogerontology · doi:10.1007/s10522-016-9637-9 · Cited by 91 · see citing works
Role of the Cytokine-like Hormone Leptin in Muscle-bone Crosstalk with Aging
Hamrick, M. W. (2017) · Journal of Bone Metabolism · doi:10.11005/jbm.2017.24.1.1 · Cited by 77 · see citing works
Role of dietary protein and muscular fitness on longevity and aging
Strasser, B., Volaklis, K., Fuchs, D., & Burtscher, M. (2018) · Aging and Disease · doi:10.14336/ad.2017.0202 · Cited by 78 · see citing works
Contribution of muscle satellite cells to sarcopenia
Huo, F., Liu, Q., & Liu, H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.892749 · Cited by 74 · see citing works
Sex differences in the response to resistance exercise training in older people
Da Boit, M., Sibson, R., Meakin, J. R., Aspden, R. M., Thies, F., Mangoni, A. A., & Gray, S. R. (2016) · Physiological Reports · doi:10.14814/phy2.12834 · Cited by 73 · see citing works
Johnson, M. L., Lalia, A. Z., Dasari, S., Pallauf, M., Fitch, M., Hellerstein, M. K., & Lanza, I. R. (2015) · Aging Cell · doi:10.1111/acel.12352 · Cited by 66 · see citing works
Dirks, M. L., Tieland, M., Verdijk, L. B., Losen, M., Nilwik, R., Mensink, M., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.02.006 · Cited by 56 · see citing works
Andreani, C., Bartolacci, C., Guescini, M., Battistelli, M., Stocchi, V., Orlando, F., Provinciali, M., Amici, A., Marchini, C., Tiano, L., et al. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/8936251 · Cited by 37 · see citing works
Thomas, E., Gentile, A., Lakicevic, N., Moro, T., Bellafiore, M., Paoli, A., Drid, P., Palma, A., & Bianco, A. (2021) · Aging Clinical and Experimental Research · doi:10.1007/s40520-021-01853-8 · Cited by 34 · see citing works
Polo-Ferrero, L., Martin, M. J., Puente-González, A. S., Barbero-Iglesias, F. J., González-Manzano, S., & Méndez-Sánchez, R. (2025) · Nutrients · doi:10.3390/nu17111822 · Cited by 15 · see citing works
- Authors
- Leenders, M., Verdijk, L. B., van der Hoeven, L., van Kranenburg, J., Nilwik, R., & van Loon, L. J. C.
- Affiliations
- Maastricht University Medical Centre (NL)
- ORCID
- Verdijk, L. B.
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-12-07
- Volume
- 68
- Issue
- 7
- Pages
- 769-779
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2154292868
- Cited by
- 226
- References
- 66
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 11 · 2023: 11 · 2022: 18 · 2021: 12 · 2020: 22 · 2019: 12 · 2018: 25 · 2017: 22 · 2016: 28 · 2015: 24 · 2014: 20 · 2013: 4
- FWCI
- 10.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journals of Gerontology Series A (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion, other-oa)
- Research Bank (Australian Catholic University) (submittedVersion)
- VUBIR (Vrije Universiteit Brussel) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- resistance training, older adults, sex differences, muscle mass, muscle strength, functional capacity, muscle fiber size, fast-twitch muscle, myonuclei, satellite cells, glycemic control, serum lipids, sarcopenia, aging
- MeSH terms
- Aged, Aging, Body Composition, Cholesterol, Female, Glycated Hemoglobin, Humans, Cholesterol, HDL, Male, Biomarkers, Absorptiometry, Photon, Muscle, Skeletal, Muscle Fibers, Skeletal, Dietary Supplements, Muscle Strength, Resistance Training, Sarcopenia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
