Toll-like receptors in innate immunity

Toll-like receptor signalling

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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A Toll-like receptor recognizes bacterial DNA

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Toll-Like Receptors

Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141126 · Cited by 6,143

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Lemaître, B., Nicolas, E., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80172-5 · Cited by 4,224

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., Taira, K., Akira, S., & Fujita, T. (2004) · Nature Immunology · doi:10.1038/ni1087 · Cited by 4,022

Macrophages, inflammation, and insulin resistance

Olefsky, J. M., & Glass, C. K. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135846 · Cited by 2,733

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., et al. (2005) · Nature · doi:10.1038/nature03464 · Cited by 2,229

Regulation of Adaptive Immunity by the Innate Immune System

Iwasaki, A., & Medzhitov, R. M. (2010) · Science · doi:10.1126/science.1183021 · Cited by 2,220

Innate immune recognition of viral infection

Kawai, T., & Akira, S. (2006) · Nature Immunology · doi:10.1038/ni1303 · Cited by 1,899

TLR signaling

Kawai, T., & Akira, S. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401850 · Cited by 1,894

Pattern recognition receptors in health and diseases

Li, D., & Wu, M. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00687-0 · Cited by 1,961

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Rathinam, V. A. K., Jiang, Z., Waggoner, S. N., Sharma, S., Cole, L. E., Waggoner, L., Vanaja, S. K., Monks, B. G., Ganesan, S., Latz, E., et al. (2010) · Nature Immunology · doi:10.1038/ni.1864 · Cited by 1,331

The role of synovitis in osteoarthritis pathogenesis

Scanzello, C. R., & Goldring, S. R. (2012) · Bone · doi:10.1016/j.bone.2012.02.012 · Cited by 1,302

The IRF Family Transcription Factors in Immunity and Oncogenesis

Tamura, T., Yanai, H., Savitsky, D., & Taniguchi, T. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090400 · Cited by 1,259

Pyroptosis: A new frontier in cancer

Fang, Y., Tian, S., Pan, Y., Li, W., Wang, Q., Tang, Y. R., Yu, T., Wu, X., Shi, Y., Ma, P., et al. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109595 · Cited by 1,073

A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways

Nguyen, M. T. A., Favelyukis, S., Nguyen, A.-K., Reichart, D., Scott, P. A., Jenn, A., Liu-Bryan, R., Glass, C. K., Neels, J. G., & Olefsky, J. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706762200 · Cited by 1,035

Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

Weber, F., Wagner, V., Rasmussen, S. B., Hartmann, R., & Paludan, S. R. (2006) · Journal of Virology · doi:10.1128/jvi.80.10.5059-5064.2006 · Cited by 957

The Inflammatory Response to Cell Death

Rock, K. L., & Kono, H. (2007) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.151456 · Cited by 979

Function of Nod‐like receptors in microbial recognition and host defense

Franchi, L., Warner, N. E., Viani, K. L., & Núñez, G. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00734.x · Cited by 938

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

Ablasser, A., Bauernfeind, F. G., Hartmann, G., Latz, E., Fitzgerald, K. A., & Hornung, V. (2009) · Nature Immunology · doi:10.1038/ni.1779 · Cited by 892

Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity

Xu, Y., Jagannath, C., Liu, X.-D., Sharafkhaneh, A., Kolodziejska, K. E., & Eissa, N. T. (2007) · Immunity · doi:10.1016/j.immuni.2007.05.022 · Cited by 880

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

Schaefer, L., Babelova, A., Kiss, E., Hausser, H.-J., Baliova, M., Krzyzankova, M., Marsche, G., Young, M. F., Mihalik, D., Götte, M., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23755 · Cited by 850

Dendritic Cells: Translating Innate to Adaptive Immunity

Steinman, R. M., & Hemmi, H. (2006) · Springer eBooks · doi:10.1007/3-540-32636-7_2 · Cited by 855

Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment

Nagai, Y., Garrett, K. P., Ohta, S., Bahrun, U., Kouro, T., Akira, S., Takatsu, K., & Kincade, P. W. (2006) · Immunity · doi:10.1016/j.immuni.2006.04.008 · Cited by 833

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivoPreprint

Shim, J., Xiao, C., Paschal, A. E., Bailey, S. T., Rao, P., Hayden, M. S., Lee, K., Bussey, C., Steckel, M., Tanaka, N., et al. (2005) · Genes & Development · doi:10.1101/gad.1360605 · Cited by 747

Toll-Like Receptors in Antiviral Innate Immunity

Lester, S. N., & Li, K. (2013) · Journal of Molecular Biology · doi:10.1016/j.jmb.2013.11.024 · Cited by 759

Recognition and Signaling by Toll-Like Receptors

West, A. P., Koblansky, A. A., & Ghosh, S. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.122303.115827 · Cited by 736

Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

Kanneganti, T., Body–Malapel, M., Amer, A. O., Park, J., Whitfield, J. R., Franchi, L., Taraporewala, Z. F., Miller, D. J., Patton, J. T., Inohara, N., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m607594200 · Cited by 706

Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

Yagi, H., Soto–Gutiérrez, A., Parekkadan, B., Kitagawa, Y., Tompkins, R. G., Kobayashi, N., & Yarmush, M. L. (2010) · Cell Transplantation · doi:10.3727/096368910x508762 · Cited by 717

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

Yvan‐Charvet, L., Wang, N., & Tall, A. R. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.179283 · Cited by 683

NLRs join TLRs as innate sensors of pathogens

Martinon, F., & Tschopp, J. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.06.004 · Cited by 673

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

Schröder, N. W. J., & Schumann, R. R. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)01308-3 · Cited by 638

Host-Bacterial Interactions in Helicobacter pylori Infection

Amieva, M. R., & El-Omar, E. M. (2008) · Gastroenterology · doi:10.1053/j.gastro.2007.11.009 · Cited by 632

Innate immunity in diabetic kidney disease

Tang, S. C. W., & Yiu, W. H. (2020) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0234-4 · Cited by 621

Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain

Choe, J., Kelker, M. S., & Wilson, I. A. (2005) · Science · doi:10.1126/science.1115253 · Cited by 620

Inflammatory Mechanisms: The Molecular Basis of Inflammation and Disease

Libby, P. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00352.x · Cited by 625

Toll-like receptors: From the discovery of NFκB to new insights into transcriptional regulations in innate immunity

Doyle, S., & O'Neill, L. A. J. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.07.010 · Cited by 594

Toll-like receptors — taking an evolutionary approach

Leulier, F., & Lemaitre, B. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2303 · Cited by 581

Pathogen recognition in the innate immune response

Kumar, H., Kawai, T., & Akira, S. (2009) · Biochemical Journal · doi:10.1042/bj20090272 · Cited by 609

Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

Deleavey, G. F., & Damha, M. J. (2012) · Chemistry & Biology · doi:10.1016/j.chembiol.2012.07.011 · Cited by 605

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

Salminen, A., Huuskonen, J., Ojala, J., Kauppinen, A., Kaarniranta, K., & Suuronen, T. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.09.002 · Cited by 581

Interferon signalling network in innate defence

Takaoka, A., & Yanai, H. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00716.x · Cited by 603

Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

Gavin, A. L., Hoebe, K. H. N., Duong, B. H., Ota, T., Martin, C. E., Beutler, B., & Nemazee, D. A. (2006) · Science · doi:10.1126/science.1135299 · Cited by 581

Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses

Chi, H., Barry, S. P., Flach, R. J. R., Wu, J. J., Jones, E. A., Bennett, A. M., & Flavell, R. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510965103 · Cited by 568

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

Hise, A. G., Tomalka, J. A., Ganesan, S., Patel, K., Hall, B. A., Brown, G. D., & Fitzgerald, K. A. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.05.002 · Cited by 582

Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions

Mohammad, S., & Thiemermann, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.594150 · Cited by 585

Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response

Panda, A., Qian, F., Mohanty, S., van Duin, D., Newman, F. K., Zhang, L., Chen, S., Towle, V., Belshe, R. B., Fikrig, E., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0901022 · Cited by 548

Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

Cao, M., Yan, H., Han, X., Weng, L., Qin, W. D., Sun, X., Lu, W., Wei, Q., Ye, J., Cai, X., et al. (2019) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-019-0817-4 · Cited by 571

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Modhiran, N., Watterson, D., Muller, D. A., Panetta, A. K., Sester, D. P., Liu, L., Hume, D. A., Stacey, K. J., & Young, P. R. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa3863 · Cited by 554

An update on vitamin D and human immunity

Hewison, M. (2011) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2011.04261.x · Cited by 562

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

Underhill, D. M., Rossnagle, E., Lowell, C. A., & Simmons, R. M. (2005) · Blood · doi:10.1182/blood-2005-03-1239 · Cited by 527

Structure and function of the epidermis related to barrier properties

Baroni, A., Buommino, E., Gregorio, V. D., Ruocco, E., Ruocco, V., & Wolf, R. (2012) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2011.08.007 · Cited by 530

Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer

Lazăr, V., Diţu, L.-M., Pîrcălăbioru, G. G., Gheorghe, I., Curuțiu, C., Holban, A. M., Picu, A. A., Petcu, L. M., & Chifiriuc, M. C. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01830 · Cited by 552

Signalling pathways in alcohol-induced liver inflammation

Mandrekar, P., & Szabó, G. (2009) · Journal of Hepatology · doi:10.1016/j.jhep.2009.03.007 · Cited by 500

Vaccine adjuvants revisited

Aguilar, J. C., & Rodríguez, E. G. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.01.111 · Cited by 499

Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions

Lyu, F., Cui, H., Pan, H., Cheung, K., Cao, X., Iatridis, J. C., & Zheng, Z. (2021) · Bone Research · doi:10.1038/s41413-020-00125-x · Cited by 494

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

Park, B., Brinkmann, M. M., Spooner, E., Lee, C. C., Kim, Y., & Ploegh, H. L. (2008) · Nature Immunology · doi:10.1038/ni.1669 · Cited by 478

Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

Arimoto, K., Takahashi, H., Hishiki, T., Konishi, H., Fujita, T., & Shimotohno, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611551104 · Cited by 482

Host–Bacterial Symbiosis in Health and Disease

Chow, J., Lee, S. M., Shen, Y. L., Khosravi, A., & Mazmanian, S. K. (2010) · Advances in immunology · doi:10.1016/b978-0-12-381300-8.00008-3 · Cited by 485

Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

Amer, A., Franchi, L., Kanneganti, T.-D., Body-Malapel, M., Özören, N., Brady, G., Meshinchi, S., Jagirdar, R., Gewirtz, A., Akira, S., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m604933200 · Cited by 453

siRNA and Innate Immunity

Robbins, M., Judge, A. D., & MacLachlan, I. (2009) · Oligonucleotides · doi:10.1089/oli.2009.0180 · Cited by 463

Heat Shock Protein gp96 Is a Master Chaperone for Toll-like Receptors and Is Important in the Innate Function of Macrophages

Yang, Y., Liu, B., Dai, J., Srivastava, P. K., Zammit, D. J., Lefrançois, L., & Li, Z. (2007) · Immunity · doi:10.1016/j.immuni.2006.12.005 · Cited by 410

MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases

Dai, R., & Ahmed, S. A. (2011) · Translational research · doi:10.1016/j.trsl.2011.01.007 · Cited by 450

Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals

Vidya, M. K., Kumar, V. G., Sejian, V., Bagath, M., Krishnan, G., & Bhatta, R. (2017) · International Reviews of Immunology · doi:10.1080/08830185.2017.1380200 · Cited by 459

Gram-positive toxic shock syndromes

Lappin, E., & Ferguson, A. J. (2009) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(09)70066-0 · Cited by 437

Chemically modified siRNA: tools and applications

Watts, J. K., Deleavey, G. F., & Damha, M. J. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2008.05.007 · Cited by 440

Innate immunity in diabetes and diabetic nephropathy

Wada, J., & Makino, H. (2015) · Nature Reviews Nephrology · doi:10.1038/nrneph.2015.175 · Cited by 441

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

Pïcard, C., von Bernuth, H., Ghandil, P., Chrabieh, M., Levy, O., Arkwright, P. D., McDonald, D. R., Geha, R. S., Takada, H., Krause, J. C., et al. (2010) · Medicine · doi:10.1097/md.0b013e3181fd8ec3 · Cited by 425

The many faces of the hygiene hypothesis

Schaub, B., Lauener, R. P., & von Mutius, E. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.03.003 · Cited by 380

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

Anderson, N., & Borlak, J. T. (2008) · Pharmacological Reviews · doi:10.1124/pr.108.00001 · Cited by 395

Inflammation and fibrosis in murine models of heart failure

Bacmeister, L., Schwarzl, M., Warnke, S., Stoffers, B., Blankenberg, S., Westermann, D., & Lindner, D. (2019) · Basic Research in Cardiology · doi:10.1007/s00395-019-0722-5 · Cited by 391

The molecular structure of the Toll-like receptor 3 ligand-binding domain

Bell, J. K., Botos, I., Hall, P. R., Askins, J., Shiloach, J., Segal, D. M., & Davies, D. R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505077102 · Cited by 387

Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

Prinz, M. (2006) · Journal of Clinical Investigation · doi:10.1172/jci26078 · Cited by 378

Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2

Funderburg, N., Lederman, M. M., Feng, Z., Drage, M. G., Jadlowsky, J. K., Harding, C. V., Weinberg, A., & Sieg, S. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702130104 · Cited by 377

Critical role of TLR4 response in the activation of microglia induced by ethanol

Fernandez-Lizarbe, S., Pascual, M., & Guerri, C. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803590 · Cited by 373

Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor

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Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-κB dependent inflammatory response☆

BOYD, J., MATHUR, S., WANG, Y., Bateman, R. M., & Walley, K. R. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.09.011 · Cited by 375

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease

Higginbotham, L., Ping, L., Dammer, E. B., Duong, D. M., Zhou, M., Gearing, M., Hurst, C., Glass, J. D., Factor, S. A., Johnson, E. C. B., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz9360 · Cited by 367

Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

Higginbotham, L., Ping, L., Dammer, E. B., Duong, D. M., Zhou, M., Gearing, M., Johnson, E. C. B., Hajjar, I., Lah, J. J., Levey, A. I., et al. (2019) · doi:10.1101/806752 · Cited by 367

Polymeric Delivery of Therapeutic Nucleic Acids

Kumar, R., Chalarca, C. F. S., Bockman, M. R., Bruggen, C. V., Grimme, C. J., Dalal, R. J., Hanson, M. G., Hexum, J. K., & Reineke, T. M. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00997 · Cited by 379

Activation of the mammalian immune system by siRNAs

Marques, J. T., & Williams, B. R. G. (2005) · Nature Biotechnology · doi:10.1038/nbt1161 · Cited by 362

Inhibition of Toll-Like Receptor Signaling as a Promising Therapy for Inflammatory Diseases: A Journey from Molecular to Nano Therapeutics

Gao, W., Xiong, Y., Li, Q., & Yang, H. Y. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00508 · Cited by 372

A comprehensive map of the toll‐like receptor signaling network

Oda, K., & Kitano, H. (2006) · Molecular Systems Biology · doi:10.1038/msb4100057 · Cited by 362

Micro RNA 145 Targets the Insulin Receptor Substrate-1 and Inhibits the Growth of Colon Cancer Cells

Shi, B., Sepp‐Lorenzino, L., di Prisco, M., Linsley, P. S., DeAngelis, T., & Baserga, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702806200 · Cited by 349

Molecular mechanisms involved in inflammasome activation

Bryant, C. E., & Fitzgerald, K. A. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.06.002 · Cited by 351

Regulation of the type I IFN induction: a current view

Honda, K., Yanai, H., Takaoka, A., & Taniguchi, T. (2005) · International Immunology · doi:10.1093/intimm/dxh318 · Cited by 357

Phages and their satellites encode hotspots of antiviral systems

Rousset, F., Depardieu, F., Miele, S., Dowding, J., Laval, A.-L., Lieberman, E., Garry, D. J., Rocha, E. P. C., Bernheim, A. G., & Bikard, D. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.02.018 · Cited by 348

The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway

Chen, C., Kao, C., & Liu, C.-M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092729 · Cited by 351

The emerging role of Toll-like receptor 4 in myocardial inflammation

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Toll-like receptors in inflammation, infection and cancer

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Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

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Cancer and Inflammation: Promise for Biologic Therapy

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Toll-Like Receptor Pathways in Autoimmune Diseases

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