DNA replication stress, genome instability and aging

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Mitochondria, Oxidants, and Aging

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Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS

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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

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Trends in oxidative aging theories

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AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

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Signals from the reproductive system regulate the lifespan of C. elegans

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The Regulation of INK4/ARF in Cancer and Aging

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Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

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Regulation of Longevity and Stress Resistance by Sch9 in Yeast

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How stem cells age and why this makes us grow old

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Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans

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Resveratrol stimulates AMP kinase activity in neurons

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Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

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The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways

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Evolutionary medicine: from dwarf model systems to healthy centenarians?

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Toward a unified theory of caloric restriction and longevity regulation

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Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis

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Calorie Restriction, Aging, and Cancer Prevention: Mechanisms of Action and Applicability to Humans

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AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer

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Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis in Human Umbilical Vein Endothelial Cells

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Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability

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The chronological life span of Saccharomyces cerevisiae

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Delayed ageing through damage protection by the Arf/p53 pathway

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Genetic analysis of yeast RAS1 and RAS2 genes

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p53: Guardian of the Genome and Policeman of the Oncogenes

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Reduced TOR Signaling Extends Chronological Life Span via Increased Respiration and Upregulation of Mitochondrial Gene Expression

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Sir2 Blocks Extreme Life-Span Extension

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Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

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RecQ helicases: suppressors of tumorigenesis and premature aging

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Isolation of quiescent and nonquiescent cells from yeast stationary-phase cultures

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Higher Respiratory Activity Decreases Mitochondrial Reactive Oxygen Release and Increases Life Span in Saccharomyces cerevisiae

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Oxidative stress mediates tau-induced neurodegeneration in Drosophila

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TOR and PKA Signaling Pathways Converge on the Protein Kinase Rim15 to Control Entry into G0

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p53: new roles in metabolism

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A redox cycle within the cell cycle: ring in the old with the new

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Divide and Die: Cell Cycle Events as Triggers of Nerve Cell Death

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Mitochondrial Regulation of Cell Cycle Progression during Development as Revealed by the tenured Mutation in Drosophila

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TOR-Mediated Cell-Cycle Activation Causes Neurodegeneration in a Drosophila Tauopathy Model

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The DNA damage response during DNA replication

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Longevity Regulation inSaccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin

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Reduced Mcm2 Expression Results in Severe Stem/Progenitor Cell Deficiency and Cancer

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