Transient activation of β-catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice

Wnt signaling and cancer

Polakis, P. (2000) · Genes & Development · doi:10.1101/gad.14.15.1837 · Cited by 3,183

Controls of Hair Follicle Cycling

Stenn, K. S., & Paus, R. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.449 · Cited by 1,543

A Comprehensive Guide for the Accurate Classification of Murine Hair Follicles in Distinct Hair Cycle Stages

Müller-Röver, S., Foitzik, K., Paus, R., Handjiski, B., van der Veen, C., Eichmüller, S., McKay, I. A., & Stenn, K. S. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01377.x · Cited by 1,375

β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin

Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G., & Birchmeier, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00336-1 · Cited by 1,352

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

Peifer, M., & Polakis, P. (2000) · Science · doi:10.1126/science.287.5458.1606 · Cited by 1,253

De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell · doi:10.1016/s0092-8674(00)81631-1 · Cited by 1,089

WNT Signals Are Required for the Initiation of Hair Follicle Development

Andl, T., Reddy, S. T., Gaddapara, T., & Millar, S. E. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00167-3 · Cited by 1,088

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

DasGupta, R., & Fuchs, E. V. (1999) · Development · doi:10.1242/dev.126.20.4557 · Cited by 995

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.Preprint

van Genderen, C., Okamura, R. M., Fariñas, I., Quo, R. G., Parslow, T. G., Bruhn, L., & Grosschedl, R. (1994) · Genes & Development · doi:10.1101/gad.8.22.2691 · Cited by 972

Molecular Mechanisms Regulating Hair Follicle Development

Millar, S. E. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01670.x · Cited by 967

Stem Cells and Their Niches

Moore, K. A., & Lemischka, I. R. (2006) · Science · doi:10.1126/science.1110542 · Cited by 1,589

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J., & Cotsarelis, G. (2005) · Nature Medicine · doi:10.1038/nm1328 · Cited by 1,317

Capturing and profiling adult hair follicle stem cells

Morris, R. J., Liu, Y., Marles, L., Yang, Z., Trempus, C., Li, S., Lin, J. S., Sawicki, J. A., & Cotsarelis, G. (2004) · Nature Biotechnology · doi:10.1038/nbt950 · Cited by 1,283

Epidermal homeostasis: a balancing act of stem cells in the skin

Blanpain, C., & Fuchs, E. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2636 · Cited by 1,270

Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding

Ito, M., Yang, Z., Andl, T., Cui, C., Kim, N., Millar, S. E., & Cotsarelis, G. (2007) · Nature · doi:10.1038/nature05766 · Cited by 1,064

The Hair Follicle as a Dynamic Miniorgan

Schneider, M. R., Schmidt-Ullrich, R., & Paus, R. (2009) · Current Biology · doi:10.1016/j.cub.2008.12.005 · Cited by 1,119

Scratching the surface of skin development

Fuchs, E. (2007) · Nature · doi:10.1038/nature05659 · Cited by 930

Epidermal Stem Cells of the Skin

Blanpain, C., & Fuchs, E. V. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010305.104357 · Cited by 882

Telomeres and telomerase in cancer

Artandi, S. E., & DePinho, R. A. (2010) · Carcinogenesis · doi:10.1093/carcin/bgp268 · Cited by 823

Wnt signaling in development and tissue homeostasis

Steinhart, Z., & Angers, S. (2018) · Development · doi:10.1242/dev.146589 · Cited by 821

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

Greco, V., Chen, T., Rendl, M., Schober, M., Pasolli, H. A., Stokes, N., dela Cruz-Racelis, J., & Fuchs, E. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2008.12.009 · Cited by 800

No place like home: anatomy and function of the stem cell niche

Jones, D. L., & Wagers, A. J. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2319 · Cited by 830

Telomerase modulates Wnt signalling by association with target gene chromatin

Park, J.-I., Venteicher, A. S., Hong, J. Y., Choi, J., Jun, S., Shkreli, M., Chang, W., Meng, Z., Cheung, P., Ji, H., et al. (2009) · Nature · doi:10.1038/nature08137 · Cited by 707

Characterization and isolation of stem cell-enriched human hair follicle bulge cells

Ohyama, M. (2005) · Journal of Clinical Investigation · doi:10.1172/jci26043 · Cited by 623

Epithelial Stem Cells: Turning over New Leaves

Blanpain, C., Horsley, V., & Fuchs, E. V. (2007) · Cell · doi:10.1016/j.cell.2007.01.014 · Cited by 607

Epithelial Stem Cells: A Folliculocentric View

Cotsarelis, G. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700376 · Cited by 554

The hair cycle

Alonso, L. C., & Fuchs, E. V. (2006) · Journal of Cell Science · doi:10.1242/jcs.02793 · Cited by 557

Androgenetic alopecia: a review

Lolli, F., Pallotti, F., Rossi, A., Fortuna, M. C., Caro, G., Lenzi, A., Sansone, A., & Lombardo, F. P. (2017) · Endocrine · doi:10.1007/s12020-017-1280-y · Cited by 582

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

Martínez, P., & Blasco, M. A. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3025 · Cited by 468

Skin stem cells: rising to the surface

Fuchs, E. V. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200708185 · Cited by 450

Sox9 Is Essential for Outer Root Sheath Differentiation and the Formation of the Hair Stem Cell Compartment

Vidal, V., Chaboissier, M., Lützkendorf, S., Cotsarelis, G., Mill, P., Hui, C., Ortonne, N., Ortonne, J. P., & Schedl, A. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.064 · Cited by 427

β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

Enshell‐Seijffers, D., Lindon, C., Kashiwagi, M., & Morgan, B. A. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.01.016 · Cited by 408

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

Horsley, V., Aliprantis, A. O., Polak, L., Glimcher, L. H., & Fuchs, E. (2008) · Cell · doi:10.1016/j.cell.2007.11.047 · Cited by 424

Signaling Involved in Hair Follicle Morphogenesis and Development

Pisal, R. V., Dev, K., Diaz, D. C., Qureshi, W. M. S., Filip, S., & Mokrý, J. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15011647 · Cited by 404

Defining the impact of β-catenin/Tcf transactivation on epithelial stem cellsPreprint

Lowry, W. E., Blanpain, C., Nowak, J. A., Guasch, G., Lewis, L. E., & Fuchs, E. V. (2005) · Genes & Development · doi:10.1101/gad.1324905 · Cited by 402

Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling

Sennett, R., & Rendl, M. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.08.011 · Cited by 387

A Wnt Survival Guide: From Flies to Human Disease

Chien, A. J., Conrad, W. H., & Moon, R. T. (2009) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.445 · Cited by 382

Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

Celso, C. L., Prowse, D. M., & Watt, F. M. (2004) · Development · doi:10.1242/dev.01052 · Cited by 339

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

Choi, J., Southworth, L. K., Sarin, K. Y., Venteicher, A. S., Ma, W., Chang, W., Cheung, P., Jun, S., Artandi, M. K., Shah, N., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.0040010 · Cited by 336

Distinct Functions for Wnt/β-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis

Choi, Y. S., Zhang, Y., Xu, M., Yang, Y., Ito, M., Peng, T., Cui, Z., Nagy, A., Hadjantonakis, A., Lang, R. A., et al. (2013) · Cell stem cell · doi:10.1016/j.stem.2013.10.003 · Cited by 332

In search of the “hair cycle clock”: a guided tour

Paus, R., & Foitzik, K. (2004) · Differentiation · doi:10.1111/j.1432-0436.2004.07209004.x · Cited by 324

Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

Rabbani, P. S., Takeo, M., Chou, W. C., Myung, P. S., Bosenberg, M., Chin, L., Taketo, M. M., & Ito, M. (2011) · Cell · doi:10.1016/j.cell.2011.05.004 · Cited by 322

A family business: stem cell progeny join the niche to regulate homeostasis

Hsu, Y., & Fuchs, E. V. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3272 · Cited by 316

Catenins: Keeping Cells from Getting Their Signals Crossed

Pérez‐Moreno, M., & Fuchs, E. V. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.10.010 · Cited by 309

Tcf3 Governs Stem Cell Features and Represses Cell Fate Determination in Skin

Nguyen, H., Rendl, M., & Fuchs, E. V. (2006) · Cell · doi:10.1016/j.cell.2006.07.036 · Cited by 287

WNT/β-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells

Hao, J., Li, T.-G., Qi, X., Zhao, D., & Zhao, G.-Q. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.11.011 · Cited by 295

Wnt Signaling in Skin Development, Homeostasis, and Disease

Lim, X., & Nusse, R. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008029 · Cited by 268

The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair FolliclePreprint

Morgan, B. A. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a015180 · Cited by 246

Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration

Myung, P. S., Takeo, M., Ito, M., & Atit, R. P. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.230 · Cited by 242

β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicles in Adult Epidermis without Recruitment of Bulge Stem Cells

Silva-Vargas, V., Celso, C. L., Giangreco, A., Ofstad, T. A., Prowse, D. M., Braun, K. M., & Watt, F. M. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.04.013 · Cited by 240

More than one way to skin . . .

Fuchs, E., & Horsley, V. (2008) · Genes & Development · doi:10.1101/gad.1645908 · Cited by 224

Wnt/beta-Catenin Signaling and Small Molecule Inhibitors

Voronkov, A. E., & Krauss, S. J. K. (2012) · Current Pharmaceutical Design · doi:10.2174/138161213804581837 · Cited by 227

Wnt signaling through canonical and non-canonical pathways: Recent progress

Widelitz, R. B. (2005) · Growth Factors · doi:10.1080/08977190500125746 · Cited by 218

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

Nijhof, J. G. W., Braun, K. M., Giangreco, A., van Pelt, C., Kawamoto, H., Boyd, R. L., Willemze, R., Mullenders, L. H. F., Watt, F. M., de Gruijl, F. R., et al. (2006) · Development · doi:10.1242/dev.02443 · Cited by 211

Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

Wen, Y., Liu, Y., Xu, Y., Zhao, Y., Hua, R., Wang, K., Sun, M., Li, Y.-H., Yang, S., Zhang, X.-J., et al. (2009) · Nature Genetics · doi:10.1038/ng.276 · Cited by 209

Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis

Zhang, Y., Morris, J. P., Yan, W., Schofield, H. K., Gurney, A. L., Simeone, D. M., Millar, S. E., Hoey, T., Hebrok, M., & di Magliano, M. P. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-4384 · Cited by 207

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

Nguyen, H., Merrill, B. J., Polak, L., Nikolova, M., Rendl, M., Shaver, T. M., Pasolli, H. A., & Fuchs, E. V. (2009) · Nature Genetics · doi:10.1038/ng.431 · Cited by 203

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

Blanco, S., Kurowski, A., Nichols, J., Watt, F. M., Benitah, S. A., & Frye, M. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002403 · Cited by 197

Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells

Castellana, D., Paus, R., & Pérez‐Moreno, M. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1002002 · Cited by 189

Hairy tale of signaling in hair follicle development and cycling

Lee, J., & Tumbar, T. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.08.003 · Cited by 190

What does the concept of the stem cell niche really mean today?

Lander, A. D., Kimble, J. E., Clevers, H. C., Fuchs, E. V., Montarras, D., BUCKINGHAM, M. E., Calof, A. L., Trumpp, A., & Óskarsson, T. (2012) · BMC Biology · doi:10.1186/1741-7007-10-19 · Cited by 184

Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion

Zhang, J., He, X., Tong, W., Johnson, T., Wiedemann, L. M., Mishina, Y. M., Feng, J. Q., & Li, L. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0544 · Cited by 178

Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle

Mardaryev, A. N., Ahmed, M. I., Vlahov, N., Fessing, M. Y., Gill, J. H., Sharov, A. A., & Botchkareva, N. V. (2010) · The FASEB Journal · doi:10.1096/fj.10-160663 · Cited by 165

Smad7-Induced β-Catenin Degradation Alters Epidermal Appendage Development

Han, G., Li, A. G., Liang, Y.-Y., Owens, P., He, W., Lu, S., Yoshimatsu, Y., Wang, D., ten Dijke, P., Lin, X., et al. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.06.014 · Cited by 163

Targeted activation of β-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia

Teulière, J., Faraldo, M. M., Deugnier, M., Shtutman, M. S., Ben‐Ze'ev, A., Thiery, J. P., & Glukhova, M. A. (2004) · Development · doi:10.1242/dev.01583 · Cited by 163

Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis

Assassi, S., Swindell, W. R., Wu, M., Tan, F., Khanna, D., Furst, D. E., Tashkin, D. P., Jahan-Tigh, R. R., Mayes, M. D., Gudjonsson, J. E., et al. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39289 · Cited by 155

Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin

Collins, C. A., Kretzschmar, K., & Watt, F. M. (2011) · Development · doi:10.1242/dev.064592 · Cited by 154

Comprehensive Analysis of FGF and FGFR Expression in Skin: FGF18 Is Highly Expressed in Hair Follicles and Capable of Inducing Anagen from Telogen Stage Hair Follicles

Kawano, M., Komi-Kuramochi, A., Asada, M., Suzuki, M., Oki, J., Jiang, J., & Imamura, T. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23693.x · Cited by 147

Hairless triggers reactivation of hair growth by promoting Wnt signaling

Beaudoin, G. M. J., Sisk, J. M., Coulombe, P. A., & Thompson, C. C. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507609102 · Cited by 149

Vitamin D receptor is essential for normal keratinocyte stem cell function

Cianferotti, L., Cox, M. K., Skorija, K., & Demay, M. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702884104 · Cited by 148

Fibroblast Growth Factors Stimulate Hair Growth through β -Catenin and Shh Expression in C57BL/6 Mice

Lin, W., Xiang, L., Shi, H., Zhang, J., Jiang, L., Cai, P., Lin, Z., Lin, B., Huang, Y., Zhang, H., et al. (2015) · BioMed Research International · doi:10.1155/2015/730139 · Cited by 151

Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells

Veltri, A., Lang, C. M. R., & Lien, W. (2017) · Stem Cells · doi:10.1002/stem.2723 · Cited by 152

Wnt Signaling through the β-Catenin Pathway Is Sufficient to Maintain, but Not Restore, Anagen-Phase Characteristics of Dermal Papilla Cells

Shimizu, H., & Morgan, B. A. (2004) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2004.22224.x · Cited by 145

Dlx3 is a crucial regulator of hair follicle differentiation and cycling

Hwang, J., Mehrani, T., Millar, S. E., & Morasso, M. I. (2008) · Development · doi:10.1242/dev.022202 · Cited by 143

Sustained epithelial β-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation

Närhi, K. M., Järvinen, E., Birchmeier, W., Taketo, M. M., Mikkola, M. L., & Thesleff, I. (2008) · Development · doi:10.1242/dev.016550 · Cited by 132

Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells

Lee, S.-H., Yoon, J., Shin, S. H., Zahoor, M., Kim, H. J., Park, P. J., Park, W. S., Min, D. S., Kim, H. Y., & Choi, K. Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034152 · Cited by 129

Hedgehog Signaling Regulates Sebaceous Gland Development

Allen, M., Grachtchouk, M. A., Sheng, H., Grachtchouk, V., Wang, A., Wei, L., Liu, J., Ramı́rez, Á., METZGER, D., Chambon, P., et al. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63574-2 · Cited by 122

Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c-Myc and β-Catenin

Celso, C. L., Berta, M., Braun, K. M., Frye, M., Lyle, S. R., Zouboulis, C. C., & Watt, F. M. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0651 · Cited by 120

β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche

Deschene, E. R., Myung, P. S., Rompolas, P., Zito, G., Sun, T. Y., Taketo, M. M., Saotome, I., & Greco, V. (2014) · Science · doi:10.1126/science.1248373 · Cited by 117

The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities

Yu, M. S., Qin, K. H., Fan, J., Zhao, G., Zhao, P., Zeng, W., Chen, C., Wang, A., Wang, Y., Zhong, J., et al. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.04.042 · Cited by 125

Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and β-catenin expression in C57BL/6 mice

Park, H.-J., Zhang, N., & Park, D. K. (2011) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2011.03.028 · Cited by 116

Immune modulation of hair follicle regeneration

Rahmani, W. M., Sinha, S., & Biernaskie, J. A. (2020) · npj Regenerative Medicine · doi:10.1038/s41536-020-0095-2 · Cited by 113

Development and Homeostasis of the Skin EpidermisPreprint

Sotiropoulou, P., & Blanpain, C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008383 · Cited by 112

Hair growth-promoting activity of hot water extract of Thuja orientalis

Zhang, N., Park, D. K., & Park, H.-J. (2013) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-13-9 · Cited by 97

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria

Chiodi, I., & Mondello, C. (2012) · Frontiers in Oncology · doi:10.3389/fonc.2012.00133 · Cited by 98

Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin

Roh, C., Tao, Q., & Lyle, S. R. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00134.2004 · Cited by 94

Apoptotic extracellular vesicles are metabolized regulators nurturing the skin and hair

Ma, L., Chen, C., Liu, D., Huang, Z., Li, J., Liu, H., Kwok, R. T. K., Tang, B. Z., Sui, B., Zhang, X., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.04.022 · Cited by 94

Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance

Lin, K., Chudova, D. I., Hatfield, G. W., Smyth, P., & D, B. A. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407114101 · Cited by 94

A network of Wnt, hedgehog and BMP signaling pathways regulates tooth replacement in snakes

Handrigan, G. R., & Richman, J. M. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.09.003 · Cited by 91

Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine

Mistriotis, P., & Andreadis, S. T. (2012) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2012.0422 · Cited by 87

P-Cadherin Regulates Human Hair Growth and Cycling via Canonical Wnt Signaling and Transforming Growth Factor-β2

Samuelov, L., Sprecher, E., Tsuruta, D., Bı́ró, T., Kloepper, J. E., & Paus, R. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.171 · Cited by 87

Wnt signaling in skin organogenesis

Widelitz, R. B. (2008) · Organogenesis · doi:10.4161/org.4.2.5859 · Cited by 85

Building Epithelial Tissues from Skin Stem CellsPreprint

Fuchs, E. V., & Nowak, J. A. (2008) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2008.73.032 · Cited by 89

Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

Ober-Reynolds, B., Wang, C., Ko, J. M., Rios, E. J., Aasi, S. Z., Davis, M. M., Oro, A. E., & Greenleaf, W. J. (2023) · Nature Genetics · doi:10.1038/s41588-023-01445-4 · Cited by 83

Yap Controls Stem/Progenitor Cell Proliferation in the Mouse Postnatal Epidermis

Beverdam, A., Claxton, C., Zhang, X., James, G., Harvey, K. F., & Key, B. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.430 · Cited by 81

Home sweet home: skin stem cell niches

Goldstein, J., & Horsley, V. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-0943-3 · Cited by 80

Mechanism of action of herbs and their active constituents used in hair loss treatment

Herman, A., & Herman, A. P. (2016) · Fitoterapia · doi:10.1016/j.fitote.2016.08.008 · Cited by 82

Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

Geng, R., Yuan, C., & Chen, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062704 · Cited by 76

Functional anatomy of the hair follicle: The Secondary Hair Germ

Panteleyev, A. A. (2018) · Experimental Dermatology · doi:10.1111/exd.13666 · Cited by 74

Modulating hair follicle size with W nt10b/ DKK 1 during hair regeneration

Lei, M., Guo, H., Qiu, W., Lai, X., Yang, T., Widelitz, R. B., Chuong, C., Lian, X., & Yang, L. (2014) · Experimental Dermatology · doi:10.1111/exd.12416 · Cited by 72

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

Kretzschmar, K., Weber, C., Driskell, R. R., Calonje, E., & Watt, F. M. (2016) · Cell Reports · doi:10.1016/j.celrep.2015.12.041 · Cited by 72

Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors

Murayama, K., Kimura, T., Tarutani, M., Tomooka, M., Hayashi, R., Okabe, M., Nishida, K., Itami, S., Katayama, I., & Nakano, T. (2007) · Oncogene · doi:10.1038/sj.onc.1210274 · Cited by 71

Matrilysin-2 (Matrix Metalloproteinase-26) Is Upregulated in Keratinocytes During Wound Repair and Early Skin Carcinogenesis

Ahokas, K., Skoog, T., Suomela, S., Jeskanen, L., Impola, U., Isaka, K., & Saarialho‐Kere, U. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23640.x · Cited by 71

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Griffin, M., Huber, J., Fahy, E. J., Quarto, N., & Longaker, M. T. (2021) · Medicinal Research Reviews · doi:10.1002/med.21853 · Cited by 68

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Kretzschmar, K., Cottle, D. L., Schweiger, P. J., & Watt, F. M. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.242 · Cited by 66

Frizzled 7 Maintains the Undifferentiated State of Human Limbal Stem/Progenitor Cells

Mei, H., Nakatsu, M. N., Baclagon, E., & Deng, S. X. (2013) · Stem Cells · doi:10.1002/stem.1582 · Cited by 71

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Crabtree, J. S., Kilbourne, E. J., Peano, B. J., Chippari, S. M., Kenney, T. F., McNally, C., Wang, W., Harris, H. A., Winneker, R. C., Nagpal, S., et al. (2010) · Endocrinology · doi:10.1210/en.2009-1474 · Cited by 66

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Hardman, M. J., Liu, K., Avilion, A. A., Merritt, A. J., Brennan, K. R., Garrod, D. R., & Byrne, C. R. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.3.969-978.2005 · Cited by 66

Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways

Abdin, R., Zhang, Y., & Jimenez, J. J. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.843127 · Cited by 75

Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk

Zito, G., Saotome, I., Liu, Z. Z., Ferro, E. G., Sun, T. Y., Nguyen, D. X., Bilgüvar, K., Ko, C. J., & Greco, V. (2014) · Nature Communications · doi:10.1038/ncomms4543 · Cited by 63

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Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell · doi:10.1016/s0092-8674(00)81631-1 · Cited by 1,089

One Transgene: Two Outcomes

(2002) · Science s STKE · doi:10.1126/stke.2002.143.tw276

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Mater, D. S. V. (2006) · Deep Blue (University of Michigan)

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Deschene, E. R., Myung, P. S., Rompolas, P., Zito, G., Sun, T. Y., Taketo, M. M., Saotome, I., & Greco, V. (2014) · Science · doi:10.1126/science.1248373 · Cited by 117

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Närhi, K. M., Järvinen, E., Birchmeier, W., Taketo, M. M., Mikkola, M. L., & Thesleff, I. (2008) · Development · doi:10.1242/dev.016550 · Cited by 132