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Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing: Regulated intramembrane proteolysis and APP processing

Lichtenthaler, Stefan F., Haass, Christian, Steiner, Harald·2011·Journal of Neurochemistry
DOI 10.1111/j.1471-4159.2011.07248.x
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  • After initial BACE1 cleavage, the resulting C-terminal, membrane-bound protein fragments of several membrane proteins, including APP and SEZ6L, are further processed within their transmembrane domains by γ-secretase, in a process referred to as regulated intramembrane proteolysis.

    “After initial BACE1 cleavage, the resulting C-terminal, membrane-bound protein fragments of several membrane proteins, including APP and SEZ6L [17], are further processed within their transmembrane domains by γ-secretase, in a process referred to as regulated intramembrane proteolysis [41]”

    From Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons (2016) · cites this paper as [41]

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Metadata

Authors
Lichtenthaler, S. F., Haass, C., & Steiner, H.
Venue
Journal of Neurochemistry
Publisher
Wiley
Published
2011-04-14
Volume
117
Issue
5
Pages
779-796
ISSN
0022-3042
DOI
10.1111/j.1471-4159.2011.07248.x
Cited by
205
References
13
Language
en
Licence
doi.wiley.com/10.1002/tdm_license_1 (tdm, 1601 d)

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