Cited by 551Nutrition and Health in AgingMuscle metabolism and nutritionMuscle Physiology and Disorders

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Effects of Exercise and Amino Acid Supplementation on Body Composition and Physical Function in Community‐Dwelling Elderly Japanese Sarcopenic Women: A Randomized Controlled Trial

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Kim, Hun Kyung, Suzuki, Takao, Saito, Kyoko, Yoshida, Hideyo, Kobayashi, Hisamine, Kato, Hiroyuki, Katayama, Miwa·2012·Journal of the American Geriatrics Society

DOI 10.1111/j.1532-5415.2011.03776.x

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Abstract

Objectives: To evaluate the effectiveness of exercise and amino acid supplementation in enhancing muscle mass and strength in community‐dwelling elderly sarcopenic women. Design: Randomized controlled trial. Setting: Urban community in T okyo, J apan. Participants: One hundred fifty‐five women aged 75 and older were defined as sarcopenic and randomly assigned to one of four groups: exercise and amino acid supplementation (exercise + AAS ; n = 38), exercise (n = 39), amino acid supplementation ( AAS ; n = 39), or health education ( HE ; n = 39). Intervention: The exercise group attended a 60‐minute comprehensive training program twice a week, and the AAS group ingested 3 g of a leucine‐rich essential amino acid mixture twice a day for 3 months. Measurements: Body composition was determined using bioelectrical impedance analysis. Data from interviews and functional fitness parameters such as muscle strength and walking ability were collected at baseline and after the 3‐month intervention. Results: A significant group × time interaction was seen in leg muscle mass ( P = .007), usual walking speed ( P = .007), and knee extension strength ( P = .017). The within‐group analysis showed that walking speed significantly increased in all three intervention groups, leg muscle mass in the exercise + AAS and exercise groups, and knee extension strength only in the exercise + AAS group (9.3% increase, P = .01). The odds ratio for leg muscle mass and knee extension strength improvement was more than four times as great in the exercise + AAS group (odds ratio = 4.89, 95% confidence interval = 1.89–11.27) as in the HE group. Conclusion: The data suggest that exercise and AAS together may be effective in enhancing not only muscle strength, but also combined variables of muscle mass and walking speed and of muscle mass and strength in sarcopenic women.

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“Mini-mental state”
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Psychophysical bases of perceived exertion
BORG, G. A. V. (1982) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-198205000-00012 · Cited by 16,580
Sarcopenia: European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601
A power primer.
Cohen, J. (1992) · Psychological Bulletin · doi:10.1037//0033-2909.112.1.155 · Cited by 8,771
Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004
Exercise training and nutritional supplementation for physical frailty in very elderly people
Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857
Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography
Mitsiopoulos, N., Baumgartner, R. N., Heymsfield, S. B., Lyons, W., Gallagher, D., & Ross, R. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.1.115 · Cited by 1,522
Estimation of skeletal muscle mass by bioelectrical impedance analysis
Janssen, I., Heymsfield, S. B., Baumgartner, R. N., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.2.465 · Cited by 1,482
Progressive resistance strength training for improving physical function in older adults
Liu, C.-J., & Latham, N. K. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002759.pub2 · Cited by 1,258
Summary comments
Rosenberg, I. H. (1989) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.5.1231 · Cited by 1,234

Show all 37 references

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Authors: Kim, H. K., Suzuki, T., Saito, K., Yoshida, H., Kobayashi, H., Kato, H., & Katayama, M.
Affiliations: Tokyo Metropolitan Institute of Gerontology (JP)
National Institute for Longevity Sciences Aichi Japan
Ajinomoto (Japan) (JP)
Corresponding author: Kim, Hun Kyung
ORCID: Suzuki, Takao
Saito, Kyoko
Kobayashi, Hisamine
Kato, Hiroyuki
Venue: Journal of the American Geriatrics Society
Publisher: Wiley
Published: 2011-12-05
Volume: 60
Issue: 1
Pages: 16-23
ISSN: 0002-8614 (ISSN-L)
1532-5415
DOI: 10.1111/j.1532-5415.2011.03776.x
OpenAlex: W2074524235
Cited by: 551
References: 37
Citations by year: 2026: 25 · 2025: 36 · 2024: 33 · 2023: 44 · 2022: 47 · 2021: 51 · 2020: 51 · 2019: 57 · 2018: 45 · 2017: 45 · 2016: 36 · 2015: 31 · 2014: 26 · 2013: 16 · 2012: 7
FWCI: 10.69
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of the American Geriatrics Society (publishedVersion)
PubMed (publishedVersion)
Funders: Japan Society for the Promotion of Science (22300243)
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Keywords: sarcopenia, older women, exercise training, amino acid supplementation, muscle mass, muscle strength, walking speed, quadriceps strength, body composition, community-dwelling older adults, health education
MeSH terms: Aged, Amino Acids, Essential, Body Composition, Exercise Therapy, Female, Follow-Up Studies, Humans, Japan, Motor Activity, Patient Education as Topic, Retrospective Studies, Exercise, Geriatric Assessment, Incidence, Treatment Outcome, Dietary Supplements, Muscle Strength, Sarcopenia

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Effects of Exercise and Amino Acid Supplementation on Body Composition and Physical Function in Community‐Dwelling Elderly Japanese Sarcopenic Women: A Randomized Controlled Trial

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