How effective are lifestyle changes in the prevention of type 2 diabetes mellitus?
Abstract
Obesity and impaired glucose tolerance are associated with a greater risk for a number of conditions, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, coagulation abnormalities, inflammatory markers, and coronary heart disease. Lifestyle changes can delay or prevent the development of type 2 diabetes in patients with obesity and impaired glucose tolerance. The risks improve with weight loss and increased physical activity. A decrease of 7% to 10% or more from baseline weight can have a significant effect. This has now been documented in a number of randomized, controlled studies.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Modest reductions in weight can lead to important health benefits.
“though modest reductions in weight can lead to important health benefits (Pi-Sunyer 2007; Stevens 2001).”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Pi-Sunyer 2007
Cites
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011 · see citing works
Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873 · see citing works
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
King, H. O. M., Aubert, R. E., & Herman, W. H. (1998) · Diabetes Care · doi:10.2337/diacare.21.9.1414 · Cited by 6,267 · see citing works
Prevalence and trends in obesity among US adults, 1999–2000
Flegal, K. M. (2002) · JAMA · doi:10.1001/jama.288.14.1723 · Cited by 6,190 · see citing works
Global and societal implications of the diabetes epidemic
Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883 · see citing works
The Disease Burden Associated With Overweight and Obesity
Must, A. (1999) · JAMA · doi:10.1001/jama.282.16.1523 · Cited by 4,804 · see citing works
Pan, X.-R., Li, G.-W., Hu, Y.-H., Wang, J.-X., Yang, W.-Y., An, Z.-X., Hu, Z.-X., Juan-Lin, Xiao, J.-Z., Cao, H.-B., et al. (1997) · Diabetes Care · doi:10.2337/diacare.20.4.537 · Cited by 4,320 · see citing works
Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543 · see citing works
Overweight and obesity in the United States: prevalence and trends, 1960–1994
Flegal, K., Carroll, M., Kuczmarski, R., & Johnson, C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800541 · Cited by 3,045 · see citing works
The Continuing Epidemics of Obesity and Diabetes in the United States
Mokdad, A. H. (2001) · JAMA · doi:10.1001/jama.286.10.1195 · Cited by 2,730 · see citing works
Cellular mechanisms of insulin resistance
Shulman, G. I. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10583 · Cited by 2,714 · see citing works
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703 · see citing works
Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., & Spiegelman, B. M. (1996) · Science · doi:10.1126/science.271.5249.665 · Cited by 2,630 · see citing works
Years of Life Lost Due to Obesity
Fontaine, K. R., Redden, D. T., Wang, C., Westfall, A. O., & Allison, D. B. (2003) · JAMA · doi:10.1001/jama.289.2.187 · Cited by 2,498 · see citing works
The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM
DeFronzo, R. A. (1988) · Diabetes · doi:10.2337/diab.37.6.667 · Cited by 2,456 · see citing works
Weight gain as a risk factor for clinical diabetes mellitus in women
Colditz, G. A., Willett, W. C., Rotnitzky, A., & Manson, J. E. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-7-199504010-00001 · Cited by 2,064 · see citing works
Larsson, B., Svärdsudd, K., Welin, L., Wilhelmsen, L., Björntorp, P. A., & Tibblin, G. (1984) · BMJ · doi:10.1136/bmj.288.6428.1401 · Cited by 1,931 · see citing works
Annual Deaths Attributable to Obesity in the United States
Allison, D. B. (1999) · JAMA · doi:10.1001/jama.282.16.1530 · Cited by 1,868 · see citing works
Obesity, Fat Distribution, and Weight Gain as Risk Factors for Clinical Diabetes in Men
Chan, J. M., Rimm, E. B., Colditz, G. A., Stampfer, M. J., & Willett, W. C. (1994) · Diabetes Care · doi:10.2337/diacare.17.9.961 · Cited by 1,808 · see citing works
Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM
Boden, G. (1997) · Diabetes · doi:10.2337/diab.46.1.3 · Cited by 1,728 · see citing works
Lapidus, L., Bengtsson, C., Larsson, B., Pennert, K. M., Rybo, E., & Sjöström, L. (1984) · BMJ · doi:10.1136/bmj.289.6454.1257 · Cited by 1,657 · see citing works
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Cardiology in Review · doi:10.1097/01.crd.0000380842.14048.7e · Cited by 1,600 · see citing works
Mechanism of free fatty acid-induced insulin resistance in humans.
Roden, M., Price, T. B., Perseghin, G., Petersen, K. F., Rothman, D. L., Cline, G. W., & Shulman, G. I. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118742 · Cited by 1,539 · see citing works
Itani, S. I., Ruderman, N. B., Schmieder, F., & Boden, G. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2005 · Cited by 1,390 · see citing works
Pi‐Sunyer, F. X. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-7_part_2-199310011-00006 · Cited by 1,384 · see citing works
Self-citationMartin, B. C., Warram, J. H., Krolewski, A. S., Soeldner, J. S., Kahn, C. R., Martin, B. C., & Bergman, R. N. (1992) · The Lancet · doi:10.1016/0140-6736(92)92814-v · Cited by 1,158 · see citing works
Ohlson, L., Larsson, B., Svärdsudd, K., Welin, L., Eriksson, H., Wilhelmsen, L., Björntorp, P., & Tibblin, G. (1985) · Diabetes · doi:10.2337/diab.34.10.1055 · Cited by 1,143 · see citing works
Cusi, K., Maezono, K., Osman, A., Pendergrass, M., Patti, M. E., Pratipanawatr, T., DeFronzo, R. A., Kahn, C. R., & Mandarino, L. J. (2000) · Journal of Clinical Investigation · doi:10.1172/jci7535 · Cited by 1,139 · see citing works
"Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes.
Björntorp, P. A. (1990) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.10.4.493 · Cited by 1,115 · see citing works
Kelley, D. E., Goodpaster, B., Wing, R. R., & Simoneau, J.-A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.6.e1130 · Cited by 1,096 · see citing works
Eriksson, K. F., & Lindg�rde, F. (1991) · Diabetologia · doi:10.1007/bf00400196 · Cited by 1,092 · see citing works
Orchard, T. J., Temprosa, M., Goldberg, R., Haffner, S., Ratner, R., Marcovina, S., Fowler, S., & for the Diabetes Prevention Program Research Group (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-8-200504190-00009 · Cited by 948 · see citing works
Davidson, M. H., Hauptman, J., DiGirolamo, M., Foreyt, J. P., Halsted, C. H., Heber, D., Heimburger, D. C., Lucas, C. P., Robbins, D. C., Chung, J., et al. (1999) · JAMA · doi:10.1001/jama.281.3.235 · Cited by 947 · see citing works
Beneficial health effects of modest weight loss.
Goldstein, D. J. (1992) · PubMed · Cited by 915 · see citing works
Early Metabolic Defects in Persons at Increased Risk for Non-Insulin-Dependent Diabetes Mellitus
Eriksson, J., Franssila-Kallunki, A., Ekstrand, A., Saloranta, C., Widén, E., Schalin, C., & Groop, L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198908103210601 · Cited by 807 · see citing works
Diagnosis and Management of the Metabolic Syndrome
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169405 · Cited by 803 · see citing works
Bugianesi, E., Gastaldelli, A., Vanni, E., Gambino, R., Cassader, M., Baldi, S., Ponti, V., Pagano, G., Ferrannini, E., & Rizzetto, M. (2005) · Diabetologia · doi:10.1007/s00125-005-1682-x · Cited by 770 · see citing works
WEIGHT AS A RISK FACTOR FOR CLINICAL DIABETES IN WOMEN
Colditz, G. A., Willett, W. C., Stampfer, M. J., Manson, J. E., Hennekens, C. H., Arky, R. A., & Speizer, F. E. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115686 · Cited by 733 · see citing works
(1999) · Diabetes Care · doi:10.2337/diacare.22.4.623 · Cited by 725 · see citing works
Influence of body fat distribution on free fatty acid metabolism in obesity.
Jensen, M. D., Haymond, M. W., Rizza, R. A., Cryer, P. E., & Miles, J. M. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113997 · Cited by 683 · see citing works
Sjöström, C. D., Lissner, L., Wedel, H., & Sjöström, L. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00436.x · Cited by 678 · see citing works
Etiopathogenesis of Nonalcoholic Steatohepatitis
Chitturi, S., & Farrell, G. C. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-12927 · Cited by 664 · see citing works
Carey, D., Jenkins, A. B., Campbell, L. V., Freund, J., & Chisholm, D. J. (1996) · Diabetes · doi:10.2337/diab.45.5.633 · Cited by 659 · see citing works
Hollander, P. A., Elbein, S. C., Hirsch, I. B., Kelley, D., McGill, J., Taylor, T., Weiss, S. R., Crockett, S. E., Kaplan, R. A., Comstock, J., et al. (1998) · Diabetes Care · doi:10.2337/diacare.21.8.1288 · Cited by 654 · see citing works
Edelstein, S. L., Knowler, W. C., Bain, R. P., Andres, R., Barrett-Connor, E. L., Dowse, G. K., Haffher, S. M., Pettitt, D. J., Sorkin, J. D., Muller, D. C., et al. (1997) · Diabetes · doi:10.2337/diab.46.4.701 · Cited by 641 · see citing works
Standards of Medical Care for Patients With Diabetes Mellitus
American Diabetes Association (2003) · Diabetes Care · doi:10.2337/diacare.26.2007.s33 · Cited by 610 · see citing works
Boden, G., Lebed, B., Schatz, M., Homko, C., & Lemieux, S. (2001) · Diabetes · doi:10.2337/diabetes.50.7.1612 · Cited by 597 · see citing works
Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus.
Polonsky, K. S., Given, B. D., Hirsch, L. J., Tillil, H., Shapiro, E. T., Beebe, C., Frank, B. H., Galloway, J. A., & Van Cauter, E. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805123181903 · Cited by 567 · see citing works
Feinstein, R., Kanety, H., Papa, M. Z., Lunenfeld, B., & Karasik, A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74276-8 · Cited by 550 · see citing works
Smith, S. C., Jr. (2019) · PubMed · doi:10.17615/x6gg-7674 · Cited by 548 · see citing works
Lang, C. H., Dobrescu, C., & Bagby, G. J. (1992) · Endocrinology · doi:10.1210/endo.130.1.1727716 · Cited by 535 · see citing works
Perry, I. J., Wannamethee, S. G., Walker, M. K., Thomson, A. G., Whincup, P. H., & Shaper, A. G. (1995) · BMJ · doi:10.1136/bmj.310.6979.560 · Cited by 532 · see citing works
Intramuscular lipid content is increased in obesity and decreased by weight loss
Goodpaster, B. H., Theriault, R., Watkins, S. C., & Kelley, D. E. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80010-4 · Cited by 526 · see citing works
He, J., Watkins, S., & Kelley, D. E. (2001) · Diabetes · doi:10.2337/diabetes.50.4.817 · Cited by 518 · see citing works
Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover.
Unger, R. H., & Zhou, Y. (2001) · Diabetes · doi:10.2337/diabetes.50.2007.s118 · Cited by 476 · see citing works
Després, J., Nadeau, A., Tremblay, A., Ferland, M., Moorjani, S., Lupien, P. J., Thériault, G., Pinault, S., & Bouchard, C. (1989) · Diabetes · doi:10.2337/diab.38.3.304 · Cited by 475 · see citing works
Differences in Lipolysis between Human Subcutaneous and Omental Adipose Tissues
Arner, P. (1995) · Annals of Medicine · doi:10.3109/07853899709002451 · Cited by 448 · see citing works
Ryysy, L., Häkkinen, A. M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., & Yki-Järvinen, H. (2000) · Diabetes · doi:10.2337/diabetes.49.5.749 · Cited by 431 · see citing works
Short-Term Medical Benefits and Adverse Effects of Weight Loss
Pi-Sunyer, X. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-7_part_2-199310011-00019 · Cited by 394 · see citing works
Eriksson, J., Lindström, J., Valle, T., Aunola, S., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Lauhkonen, M., Lehto, P., et al. (1999) · Diabetologia · doi:10.1007/s001250051229 · Cited by 368 · see citing works
Correlation between muscle glycogen synthase activity and in vivo insulin action in man
Bogardus, C., Lillioja, S., Stone, K., & Mott, D. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111304 · Cited by 335 · see citing works
Skeletal muscle utilization of free fatty acids in women with visceral obesity.
Colberg, S. R., Simoneau, J. A., Thaete, F. L., & Kelley, D. E. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117864 · Cited by 320 · see citing works
Lilly Lecture 1980: Insulin Resistance and Insulin Action: An In Vitro and In Vivo Perspective
Olefsky, J. M. (1981) · Diabetes · doi:10.2337/diab.30.2.148 · Cited by 315 · see citing works
International Textbook of Diabetes Mellitus
Hollingworth, W., & Williams, D. (1997) · Wiley eBooks · Cited by 315 · see citing works
Zhi, J., Melia, A. T., Guerciolini, R., Chung, J., Kinberg, J. A., Hauptman, J. B., & Patel, I. H. (1994) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1994.104 · Cited by 278 · see citing works
Regulation by Insulin of Gene Expression in Human Skeletal Muscle and Adipose Tissue
Ducluzeau, P., Peretti, N., Laville, M., Andréelli, F., Véga, N., Riou, J. P., & Vidal, H. (2001) · Diabetes · doi:10.2337/diabetes.50.5.1134 · Cited by 263 · see citing works
The Prevention and Treatment of Obesity: Application to type 2 diabetes
Maggio, C. A., & Pi-Sunyer, X. (1997) · Diabetes Care · doi:10.2337/diacare.20.11.1744 · Cited by 261 · see citing works
The Insulin Resistance—Dyslipidemic Syndrome of Visceral Obesity: Effect on Patients' Risk
Després, J. (1998) · Obesity Research · doi:10.1002/j.1550-8528.1998.tb00683.x · Cited by 261 · see citing works
Childhood Obesity and a Diabetes Epidemic
Rocchini, A. P. (2002) · New England Journal of Medicine · doi:10.1056/nejm200203143461112 · Cited by 255 · see citing works
Mapping of Early Signaling Events in Tumor Necrosis Factor-α-mediated Lipolysis in Human Fat Cells
Rydén, M., Dicker, A., van Harmelen, V., Hauner, H., Brunnberg, M., Perbeck, L. G., Lönnqvist, F., & Arner, P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109498200 · Cited by 249 · see citing works
Lundgren, H., Bengtsson, C., Blohmé, G., Lapidus, L., & Sjöström, L. (1989) · PubMed · Cited by 246 · see citing works
Sparrow, D., Borkan, G. A., Gerzof, S. G., Wisniewski, C., & Silbert, C. K. (1986) · Diabetes · doi:10.2337/diab.35.4.411 · Cited by 237 · see citing works
Diabetes Mellitus and Macrovascular Complications: An epidemiological perspective
Donahue, R. P., & Orchard, T. J. (1992) · Diabetes Care · doi:10.2337/diacare.15.9.1141 · Cited by 230 · see citing works
Fat content in individual muscle fibers of lean and obese subjects.
Malenfant, P., Joanisse, D., Thériault, R., Goodpaster, B., Kelley, D., & Simoneau, J.-A. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801733 · Cited by 227 · see citing works
Pi-Sunyer, F. X. (1996) · Clinical Therapeutics · doi:10.1016/s0149-2918(96)80057-9 · Cited by 224 · see citing works
Self-citationEffects of Body Composition on Insulin Sensitivity
Yki‐Järvinen, H., & Koivisto, V. A. (1983) · Diabetes · doi:10.2337/diab.32.10.965 · Cited by 224 · see citing works
Segal, K. R., Edaño, A., Abalos, A. M., Albu, J., Blando, L., Tomas, M. B., & Pi‐Sunyer, F. X. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.71.6.2402 · Cited by 186 · see citing works
Self-citationHauptman, J., Jeunet, F., & Hartmann, D. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.1.309s · Cited by 182 · see citing works
Sjöström, C. D., Lissner, L., & Siostrom, L. (1997) · Obesity Research · doi:10.1002/j.1550-8528.1997.tb00572.x · Cited by 177 · see citing works
Duration of Obesity Increases the Incidence of NIDDM
Everhart, J. E., Pettitt, D. J., Bennett, P. H., & Knowler, W. C. (1992) · Diabetes · doi:10.2337/diab.41.2.235 · Cited by 168 · see citing works
Seppala-Lindroos, A. (2002) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.7.3023 · Cited by 168 · see citing works
Caro, J. F., Dohm, L. G., Pories, W. J., & Sinha, M. K. (1989) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610050804 · Cited by 165 · see citing works
Kreisberg, R. A., Boshell, B. R., DiPlacido, J., & Roddam, R. F. (1967) · New England Journal of Medicine · doi:10.1056/nejm196702092760603 · Cited by 162 · see citing works
Modan, M., Karasik, A., Halkin, H., Fuchs, Z., Lusky, A., Shitrit, A., & Modan, B. (1986) · Diabetologia · doi:10.1007/bf00456115 · Cited by 161 · see citing works
Shulman, G. I. (2004) · Physiology · doi:10.1152/physiol.00007.2004 · Cited by 147 · see citing works
Bogardus, C., Lillioja, S., Mott, D., Reaven, G. R., Kashiwagi, A., & Foley, J. E. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111274 · Cited by 131 · see citing works
Hissin, P. J., Foley, J. E., Wardzala, L. J., Karnieli, E., Simpson, I. A., Salans, L. B., & Cushman, S. W. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110674 · Cited by 117 · see citing works
Lamarche, B., Després, J., Pouliot, M., Moorjani, S., Lupien, P.-J., Thériault, G., Tremblay, A., Nadeau, A., & Bouchard, C. (1992) · Metabolism · doi:10.1016/0026-0495(92)90017-5 · Cited by 116 · see citing works
Ten-year mortality and morbidity related to serum cholesterol. A follow-up of 3.751 men aged 40-49.
Westlund, K. N., & Nicolaysen, R. (1972) · PubMed · Cited by 112 · see citing works
Regensteiner, J. G., Mayer, E. J., Shetterly, S. M., Eckel, R. H., Haskell, W. L., Marshall, J. A., Baxter, J., & Hamman, R. F. (1991) · Diabetes Care · doi:10.2337/diacare.14.11.1066 · Cited by 111 · see citing works
Kelley, D. E., Williams, K. V., Price, J. C., McKolanis, T. M., Goodpaster, B. H., & Thaete, F. L. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8027 · Cited by 104 · see citing works
Ectopic fat accumulation: an important cause of insulin resistance in humans.
Yki‐Järvinen, H. (2002) · Europe PMC (PubMed Central) · Cited by 102 · see citing works
Relationship between regional fat distribution and insulin resistance
Bonora, E. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801274 · Cited by 97 · see citing works
Impact of Obesity on Insulin Action in NIDDM
Campbell, P. J., & Carlson, M. G. (1993) · Diabetes · doi:10.2337/diab.42.3.405 · Cited by 95 · see citing works
Intentional Weight Loss and 13-Year Diabetes Incidence in Overweight Adults
Will, J. C., Williamson, D. F., Ford, E. S., Calle, E. E., & Thun, M. J. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.8.1245 · Cited by 74 · see citing works
Sm, H., Mitchell, B. D., Hazuda, H. P., & D, M. P. S. M. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.5.1312 · Cited by 73 · see citing works
Sjöström, L., Rissanen, A., Andersen, T., Boldrin, M. N., Golay, A., Koppeschaar, H. P. F., & Krempf, M. (2000) · PubMed · Cited by 71 · see citing works
Diabetes mellitus among 10,000 adult men. I. Five-year incidence and associated variables.
Medalie, J. H., Papier, C. M., Jb, H., Goldbourt, U., Tamir, S., Hn, N., & Riss, E. (1974) · PubMed · Cited by 71 · see citing works
Lemieux, S., & Després, J. (1995) · PubMed · Cited by 70 · see citing works
Jebb, S. A. (1997) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a011613 · Cited by 69 · see citing works
Visceral adiposity, fasting plasma insulin, and lipid and lipoprotein levels in Japanese Americans.
Boyko, E. J., Leonetti, D. L., Bergstrom, R. W., Newell‐Morris, L. L., & Fujimoto, W. Y. (1996) · PubMed · Cited by 65 · see citing works
Kriska, A. M., Blair, S. N., & Pereira, M. A. (1994) · PubMed · Cited by 64 · see citing works
Correlates of fasting insulin levels in young adults: The cardia study
Manolio, T. A., Savage, P. J., Burke, G. L., Hilner, J. E., Liu, K., Orchard, T. J., Sidney, S., & Oberman, A. (1991) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(91)90221-t · Cited by 59 · see citing works
Glucose Metabolism in Identical Twins Discordant for Obesity. The Critical Role of Visceral Fat
Rönnemaa, T., Koskenvuo, M., Marniemi, J., Koivunen, T., Sajantila, A., Rissanen, A., Kaitsaari, M., Bouchard, C., & Kaprio, J. A. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.2.3763 · Cited by 52 · see citing works
Overnutrition induced decrease in insulin action for glucose storage: In vivo and in vitro in man
Mott, D. M., Lillioja, S., & Bogardus, C. (1986) · Metabolism · doi:10.1016/0026-0495(86)90118-6 · Cited by 51 · see citing works
New data on the rate of progression of impaired glucose tolerance to NIDDM and predicting factors.
Heine, R. J., Nijpels, G., & Mooy, J. M. (1996) · PubMed · Cited by 45 · see citing works
Wing, R. R. (1992) · JAMA · doi:10.1001/jama.1992.03490140098042 · Cited by 41 · see citing works
Epidemiology of NIDDM in Non-Europids
de Courten, M., Bennet, P., Tuomilehto, J. O., & Zimmet, P. (1997) · Victoria University Research Repository (Victoria University) · Cited by 30 · see citing works
The Potential Role of Physical Activity in the Prevention of Non-Insulin-Dependent Diabetes Mellitus
Kriska, A. M., Blair, S. N., & Pereira, M. A. (1994) · Exercise and Sport Sciences Reviews · doi:10.1249/00003677-199401000-00007 · Cited by 26 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Randomized Clinical Trials of Weight Loss Maintenance: A Review
Turk, M. W., Yang, K., Hravnak, M., Sereika, S. M., Ewing, L. J., & Burke, L. E. (2009) · Journal of Cardiovascular Nursing · doi:10.1097/01.jcn.0000317471.58048.32 · Cited by 258 · see citing works
Wieland, L. S., Falzon, L., Sciamanna, C. N., Trudeau, K. J., Brodney Folse, S., Schwartz, J. E., & Davidson, K. W. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007675.pub2 · Cited by 195 · see citing works
Lafortune, L., Martin, S., Kelly, S., Kuhn, I., Remes, O., Cowan, A., & Brayne, C. (2016) · PLOS ONE · doi:10.1371/journal.pone.0144405 · Cited by 165 · see citing works
The Prevalence and Risk Factors of Type 2 Diabetes Mellitus (DMT2) in a Semi-Urban Saudi Population
Al Mansour, M. A. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17010007 · Cited by 153 · see citing works
- Authors
- Pi-Sunyer, F. X.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-06-28
- Volume
- 65
- Issue
- 3
- Pages
- 101-110
- ISSN
- 0029-6643 (ISSN-L)
- OpenAlex
- W2157500177
- Cited by
- 40
- References
- 109
- Citations by year
- 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2014: 4 · 2013: 1 · 2012: 4
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- type 2 diabetes prevention, lifestyle intervention, obesity, impaired glucose tolerance, weight loss, physical activity, insulin resistance, diabetes risk factors
- MeSH terms
- Diabetes Mellitus, Type 2, Humans, Life Style, Obesity, Weight Loss, Exercise, Randomized Controlled Trials as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review