Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain
Abstract
For vision, insect and vertebrate eyes use rhabdomeric and ciliary photoreceptor cells, respectively. These cells show distinct architecture and transduce the light signal by different phototransductory cascades. In the marine rag-worm Platynereis, we find both cell types: rhabdomeric photoreceptor cells in the eyes and ciliary photoreceptor cells in the brain. The latter use a photopigment closely related to vertebrate rod and cone opsins. Comparative analysis indicates that both types of photoreceptors, with distinct opsins, coexisted in Urbilateria, the last common ancestor of insects and vertebrates, and sheds new light on vertebrate eye evolution.
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At least three pan-bilaterian Opsin families are present in the sea urchin.
“Phylogenetic analysis using neighbor joining and maximum likelihood methods, combined with an examination of the diagnostic amino acid fingerprints (Arendt et al., 2004), reveals that at least three pan-bilaterian Opsin families are present in the sea urchin (Fig. 1A).”
From Opsins and clusters of sensory G-protein-coupled receptors in the sea urchin genome (2006) · cites this paper as Arendt et al., 2004
P. dumerilii has emerged as a useful lophotrochozoan reference model that allows cross-comparisons with other bilaterians in aspects such as sensory, hormonal and developmental biology.
“P. dumerilii has emerged as a useful lophotrochozoan reference model that allows cross-comparisons with other bilaterians in aspects such as sensory, hormonal and developmental biology (71–74).”
From Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in <i>Platynereis</i> (2020) · cites this paper as [71]
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Self-citation
- Authors
- Arendt, D., Tessmar-Raible, K., Snyman, H., Dorresteijn, A. W., & Wittbrodt, J.
- Affiliations
- Philipps University of Marburg (DE)
- Developmental Biology Department, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69012 Heidelberg, Germany.
- Corresponding author
- Arendt, Detlev
- Wittbrodt, Joachim
- Venue
- Science
- Published
- 2004-10-29
- Volume
- 306
- Issue
- 5697
- Pages
- 869-871
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2094217838
- Cited by
- 458
- References
- 20
- Citations by year
- 2026: 9 · 2025: 12 · 2024: 16 · 2023: 20 · 2022: 13 · 2021: 29 · 2020: 12 · 2019: 22 · 2018: 20 · 2017: 16 · 2016: 24 · 2015: 15 · 2014: 18 · 2013: 23 · 2012: 7
- FWCI
- 10.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Photoreceptor and optogenetics research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Marine Invertebrate Physiology and Ecology
- Keywords
- ciliary photoreceptors, rhabdomeric photoreceptors, rod opsin, cone opsin, opsin, Platynereis, phototransduction, Urbilateria, eye evolution, vertebrate eye evolution, photopigments
- MeSH terms
- Amino Acid Sequence, Animals, Brain, Cilia, Circadian Rhythm, Cloning, Molecular, Biological Evolution, Eye, Genes, Homeobox, Molecular Sequence Data, Phylogeny, Polychaeta, Retinal Ganglion Cells, Conserved Sequence, Rod Opsins, Photoreceptor Cells, Invertebrate, Photoreceptor Cells, Vertebrate, Gene Duplication
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