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Bacterial Community Variation in Human Body Habitats Across Space and Time
Open accessAbstract
Growing on You: The human gut and skin harbor diverse microbial communities that are known to vary strikingly among individuals. Here, Costello et al. (p. 1694 , published online 5 November) analyzed microbial diversity among several distinct body habitats (including the gut, mouth, inside the ears and nose, and skin) of the same person at different times. They found that body habitat had more influence on microbial community composition than temporal differences and variation among people. Some skin locations, such as the index finger, back of the knee, and sole of the foot, on occasion harbored higher microbial diversity than the gut or oral cavity.
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“the fine structure of the healthy microbiota seems to be unique to individuals; intra-individual differences across time are typically much smaller than differences between individuals (Caporaso et al., 2011;Costello et al., 2009).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Costello et al., 2009
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“Within individuals, small day-to-day variations in microbiota composition are generally observed (Costello et al., 2009), but these fluctuations become most obvious when we take a wider view across the lifespan (see Fig. 3).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Costello et al., 2009
In the citing paper
“Overall, no differences were identified in beta diversity since, as expected (19), longitudinal fecal samples were more similar within patients as compared to between patients, despite some drift with time in the Chaput study (Fig. S5A and S5C).”
From A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors (2021) · cites this paper as [19]
In the citing paper
“Study of short-term longitudinal samplings from half the donors found that individuals are more similar to themselves over time compared with others (Costello et al., 2009; Flores et al., 2014; Mehta et al., 2018).”
From Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers (2021) · cites this paper as Costello et al., 2009
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“Previous studies of skin environments have suggested that sebaceous environments possess specifically adapted, perhaps lipophilic bacteria (Costello et al., 2009; Grice et al., 2009).”
From Nasal Microenvironments and Interspecific Interactions Influence Nasal Microbiota Complexity and S. aureus Carriage (2013) · cites this paper as Costello et al., 2009
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“A common feature of microbial ecological studies of the anterior naris has been the dominance of Corynebacterium, Staphylococcus, and Propionibacterium species (Costello et al., 2009; Frank et al., 2010; Grice et al., 2009; TheHumanMicrobiomeProjectConsortium, 2012; Zhou et al., 2013).”
From Nasal Microenvironments and Interspecific Interactions Influence Nasal Microbiota Complexity and S. aureus Carriage (2013) · cites this paper as Costello et al., 2009
In the citing paper
“Eruption of primary deciduous dentition introduces new substrata for microbial colonization, thus introducing ecological shifts within the oral microbiome.130, 131”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [130]
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“The NIH Human Microbiome Project assessed the microbial compositions, encompassing both relative abundance and representative microbes, in 9 intraoral sites from 200 participants and found that, compared with other colonized body sites (such as the gut and the skin), the oral microbiome has the largest core set of microbes that are shared among unrelated individuals.130, 159”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [130]
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Cites
UniFrac: a New Phylogenetic Method for Comparing Microbial Communities
Lozupone, C., & Knight, R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8228-8235.2005 · Cited by 8,227
Self-citationDiversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Self-citationTurnbaugh, P. J., Ley, R. E., Hamady, M., Fraser-Liggett, C. M., Knight, R., & Gordon, J. I. (2007) · Nature · doi:10.1038/nature06244 · Cited by 6,091
Self-citationMicrobial biogeography: putting microorganisms on the map
Martiny, J. B. H., Bohannan, B. J. M., Brown, J. H., Colwell, R. K., Fuhrman, J. A., Green, J. L., Horner‐Devine, M. C., Kane, M. D., Krumins, J. A., Kuske, C. R., et al. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1341 · Cited by 3,093
Defining the normal bacterial flora of the oral cavity
Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., & Dewhirst, F. E. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5721-5732.2005 · Cited by 3,092
Topographical and Temporal Diversity of the Human Skin Microbiome
Grice, E. A., Kong, H. H., Conlan, S., Deming, C. B., Davis, J., Young, A. C., Program, N. C. S., Bouffard, G. G., Blakesley, R. W., Murray, P. R., et al. (2009) · Science · doi:10.1126/science.1171700 · Cited by 2,953
Lozupone, C., Hamady, M., Kelley, S. T., & Knight, R. D. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01996-06 · Cited by 2,717
Self-citationMICROBIAL ECOLOGY OF THE GASTROINTESTINAL TRACT
Savage, D. C. (1977) · Annual Review of Microbiology · doi:10.1146/annurev.mi.31.100177.000543 · Cited by 2,436
An ecological and evolutionary perspective on human–microbe mutualism and disease
Dethlefsen, L., McFall-Ngai, M., & Relman, D. A. (2007) · Nature · doi:10.1038/nature06245 · Cited by 1,660
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Sprockett, D., Fukami, T., & Relman, D. A. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.173 · Cited by 419
Abreu, N. A., Nagalingam, N. A., Song, Y., Roediger, F. C., Pletcher, S. D., Goldberg, A. N., & Lynch, S. V. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003783 · Cited by 415
Skin Microbiome: Looking Back to Move Forward
Kong, H. H., & Segre, J. A. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.417 · Cited by 415
Tissue-Specific Immunity at the Oral Mucosal Barrier
Moutsopoulos, N. M., & Konkel, J. E. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.08.005 · Cited by 415
Levy, R., & Borenstein, E. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300926110 · Cited by 413
Bacterial biogeography of the human digestive tract
Stearns, J. C., Lynch, M. D. J., Senadheera, D. B., Tenenbaum, H. C., Goldberg, M. B., Cvitkovitch, D. G., Croitoru, K., Moreno‐Hagelsieb, G., & Neufeld, J. D. (2011) · Scientific Reports · doi:10.1038/srep00170 · Cited by 411
Development of the human gastrointestinal microbiota and insights from high-throughput sequencing
Dominguez-Bello, M. G., Blaser, M. J., Ley, R. E., & Knight, R. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.011 · Cited by 405
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Qian, J., Hospodsky, D., Yamamoto, N., Nazaroff, W. W., & Peccia, J. (2012) · Indoor Air · doi:10.1111/j.1600-0668.2012.00769.x · Cited by 405
Schloss, P. D. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000844 · Cited by 404
Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice
Fransen, F., van Beek, A. A., Borghuis, T., Aidy, S. E., Hugenholtz, F., van der Gaast – de Jongh, C., Savelkoul, H. F. J., De Jonge, M. I., Boekschoten, M. V., Smidt, H., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01385 · Cited by 403
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Shade, A. L., Caporaso, J. G., Handelsman, J., Knight, R. D., & Fierer, N. (2013) · The ISME Journal · doi:10.1038/ismej.2013.54 · Cited by 399
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Thomas, S., Izard, J., Walsh, E. K., Batich, K. A., Chongsathidkiet, P., Clarke, G. A., Sela, D. A., Muller, A. J., Mullin, J. M., Albert, K., et al. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-2929 · Cited by 400
Knights, D., Ward, T. L., McKinlay, C. E., Miller, H., Gonzalez, A., McDonald, D., & Knight, R. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.09.013 · Cited by 396
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Kueneman, J. G., Parfrey, L. W., Woodhams, D. C., Archer, H. M., Knight, R. D., & McKenzie, V. J. (2013) · Molecular Ecology · doi:10.1111/mec.12510 · Cited by 397
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Wu, G. D., Lewis, J. D., Hoffmann, C., Chen, Y.-Y., Knight, R. D., Bittinger, K. L., Hwang, J. M., Chen, J., Berkowsky, R. W., Nessel, L. A., et al. (2010) · BMC Microbiology · doi:10.1186/1471-2180-10-206 · Cited by 388
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Self-citationAagaard, K., Petrosino, J., Keitel, W., Watson, M., Katancik, J., Garcia, N., Patel, S., Cutting, M., Madden, T., Hamilton, H., et al. (2013) · The FASEB Journal · doi:10.1096/fj.12-220806 · Cited by 383
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Shi, L., Li, Z.-H., Zheng, W., Zhao, Y., Jin, Y.-F., & Tang, Z. (2013) · Food Additives & Contaminants Part A · doi:10.1080/19440049.2013.865147 · Cited by 376
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Yang, F., Zeng, X., Ning, K., Liu, K.-L., Lo, C., Wang, W., Chen, J., Wang, D., Huang, R., Chang, X., et al. (2011) · The ISME Journal · doi:10.1038/ismej.2011.71 · Cited by 371
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Medina, R. H., Kutuzova, S., Nielsen, K. N., Johansen, J., Hansen, L. H., Nielsen, M. E., & Rasmussen, S. (2022) · ISME Communications · doi:10.1038/s43705-022-00182-9 · Cited by 370
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Bouslimani, A., Porto, C., Rath, C. M. B., Wang, M., Guo, Y., González, A., Berg-Lyons, D., Ackermann, G. L., Christensen, G. J. M., Nakatsuji, T., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424409112 · Cited by 365
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Fodor, A. A., Klem, E., Gilpin, D. F., Elborn, J. S., Boucher, R. C., Tunney, M. M., & Wolfgang, M. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045001 · Cited by 362
Madan, J. C., Koestler, D. C., Stanton, B. A., Davidson, L. E., Moulton, L. A., Housman, M. L., Moore, J. H., Guill, M. F., Morrison, H. G., Sogin, M. L., et al. (2012) · mBio · doi:10.1128/mbio.00251-12 · Cited by 361
Langenheder, S., & Székely, A. J. (2011) · The ISME Journal · doi:10.1038/ismej.2010.207 · Cited by 361
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Manichanh, C., Reeder, J., Gibert, P., Varela, E., Llopis, M., Antolı́n, M., Guigó, R., Knight, R. D., & Guarner, F. (2010) · Genome Research · doi:10.1101/gr.107987.110 · Cited by 338
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Takeshita, T., Kageyama, S., Furuta, M., Tsuboi, H., Takeuchi, K., Shibata, Y., Shimazaki, Y., Akifusa, S., Ninomiya, T., Kiyohara, Y., et al. (2016) · Scientific Reports · doi:10.1038/srep22164 · Cited by 284
Kennedy, N. A., Walker, A. W., Berry, S. H., Duncan, S. H., Farquarson, F. M., Louis, P., Thomson, J., surname):, O. M. N. N. W. T. M. A. L. (. B., Satsangi, J. J., Flint, H. J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088982 · Cited by 328
McHardy, I. H., Goudarzi, M., Tong, M., Ruegger, P. M., Schwager, E., Weger, J. R., Graeber, T. G., Sonnenburg, J. L., Horvath, S., Huttenhower, C., et al. (2013) · Microbiome · doi:10.1186/2049-2618-1-17 · Cited by 329
Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus
Moreno‐Indias, I., Cardona, F., Tinahones, F. J., & Queipo‐Ortuño, M. I. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00190 · Cited by 325
Unexpected guests in the tumor microenvironment: microbiome in cancer
Wong-Rolle, A., Wei, H. K., Zhao, C. N., & Jin, C. (2020) · Protein & Cell · doi:10.1007/s13238-020-00813-8 · Cited by 327
The microbiome in threatened species conservation
West, A. G., Waite, D. W., Deines, P., Bourne, D. G., Digby, A., McKenzie, V. J., & Taylor, M. W. (2018) · Biological Conservation · doi:10.1016/j.biocon.2018.11.016 · Cited by 324
Comparative analyses of the bacterial microbiota of the human nostril and oropharynx
Lemon, K. P., Klepac-Ceraj, V., Schiffer, H. K., Brodie, E. L., Lynch, S. V., & Kolter, R. (2010) · mBio · doi:10.1128/mbio.00129-10 · Cited by 322
A phylogenetic transform enhances analysis of compositional microbiota data
Silverman, J. D., Washburne, A., Mukherjee, S., & David, L. A. (2017) · eLife · doi:10.7554/elife.21887 · Cited by 321
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Self-citationHannigan, G. D., Meisel, J. S., Tyldsley, A. S., Zheng, Q., Hodkinson, B. P., SanMiguel, A. J., Minot, S. S., Bushman, F. D., & Grice, E. A. (2015) · mBio · doi:10.1128/mbio.01578-15 · Cited by 319
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Dorrestein, P. C., Mazmanian, S. K., & Knight, R. (2014) · Immunity · doi:10.1016/j.immuni.2014.05.015 · Cited by 317
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Johnson, C. L., & Versalovic, J. A. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2736 · Cited by 317
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Xu, H., & Li, H. (2019) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-00417-3 · Cited by 317
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Open2C, Abdennur, N., Abraham, S., Fudenberg, G., Flyamer, I. M., Galitsyna, A. A., Goloborodko, A., Imakaev, M., Oksuz, B. A., Venev, S. V., et al. (2024) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1012067 · Cited by 313
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Madore, C., Yin, Z., Leibowitz, J. A., & Butovsky, O. (2020) · Immunity · doi:10.1016/j.immuni.2019.12.003 · Cited by 313
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Arora, T., & Bäckhed, F. (2016) · Journal of Internal Medicine · doi:10.1111/joim.12508 · Cited by 312
Gorzelak, M. A., Gill, S. K., Tasnim, N., Zahra, A.-V., Jay, M., & Gibson, D. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0134802 · Cited by 311
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Frazier, T. H., DiBaise, J. K., & McClain, C. J. (2011) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607111413772 · Cited by 306
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Dutzan, N., Konkel, J. E., Greenwell-Wild, T., & Moutsopoulos, N. M. (2016) · Mucosal Immunology · doi:10.1038/mi.2015.136 · Cited by 305
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Adams, R. I., Bateman, A. C., Bik, H. M., & Meadow, J. F. (2015) · Microbiome · doi:10.1186/s40168-015-0108-3 · Cited by 305
von Hertzen, L., Hanski, I., & Haahtela, T. (2011) · The EMBO Reports · doi:10.1038/embor.2011.195 · Cited by 304
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Moissl‐Eichinger, C., Pausan, M.-R., Taffner, J., Berg, G., Bang, C., & Schmitz, R. A. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2017.07.004 · Cited by 304
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Fierer, N., & Lennon, J. T. (2011) · American Journal of Botany · doi:10.3732/ajb.1000498 · Cited by 301
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Newton, R. J., McLellan, S. L., Dila, D. K., Vineis, J. H., Morrison, H. G., Eren, A. M., & Sogin, M. L. (2015) · mBio · doi:10.1128/mbio.02574-14 · Cited by 299
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McKenzie, V. J., Bowers, R. M., Fierer, N., Knight, R. D., & Lauber, C. L. (2011) · The ISME Journal · doi:10.1038/ismej.2011.129 · Cited by 297
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Addis, M. F., Tanca, A., Uzzau, S., Oikonomou, G., Bicalho, R. C., & Moroni, P. (2016) · Molecular BioSystems · doi:10.1039/c6mb00217j · Cited by 297
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Knight, R. D., Jansson, J. K., Field, D., Fierer, N., Desai, N., Fuhrman, J. A., Hugenholtz, P., van der Lelie, D., Meyer, F., Stevens, R. L., et al. (2012) · Nature Biotechnology · doi:10.1038/nbt.2235 · Cited by 294
Self-citationHugerth, L. W., Muller, E. E. L., Hu, Y. O. O., Lebrun, L., Roume, H., Lundin, D., Wilmes, P., & Andersson, A. F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095567 · Cited by 293
Metadata
- Authors
- Costello, E. K., Lauber, C. L., Hamady, M., Fierer, N., Gordon, J. I., & Knight, R.
- Affiliations
- University of Colorado Boulder (US)
- Cooperative Institute for Research in Environmental Sciences (US)
- Washington University in St. Louis (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Knight, Rob
- Venue
- Science
- Published
- 2009-12-18
- Volume
- 326
- Issue
- 5960
- Pages
- 1694-1697
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC3602444
- OpenAlex
- W1989889539
- Cited by
- 3,231
- References
- 17
- Citations by year
- 2026: 83 · 2025: 145 · 2024: 160 · 2023: 166 · 2022: 197 · 2021: 230 · 2020: 234 · 2019: 217 · 2018: 233 · 2017: 267 · 2016: 210 · 2015: 217 · 2014: 197 · 2013: 237 · 2012: 192
- FWCI
- 58.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- Crohn's and Colitis Foundation
- National Institute of General Medical Sciences (T32GM065103)
- National Institute of Diabetes and Digestive and Kidney Diseases (P50DK064540, P01DK078669, DK78669, DK64540)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- human microbiome, bacterial community composition, biogeography, skin microbiome, gut microbiota, oral microbiota, temporal stability, interpersonal variability, community assembly, healthy adults
- MeSH terms
- Adult, Bacteria, DNA, Bacterial, DNA, Ribosomal, Ear Canal, Feces, Female, Hair, Humans, Male, Middle Aged, Mouth, Nose, Phylogeny, RNA, Ribosomal, 16S, Skin, Time Factors, Cluster Analysis, Genes, rRNA, Principal Component Analysis, Biodiversity, Metagenome
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