ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

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    Cherry, Jonathan D., Olschowka, John A., O’Banion, M. Kerry · 2015 · Journal of Neuroinflammation
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    Fitz, Nicholas F., Cronican, Andrea A., Lefterov, Iliya, Koldamova, Radosveta · 2013 · Science
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    Kim, Jaekwang, Yoon, Hyejin, Basak, Jacob, Kim, Jungsu · 2014 · Molecules and Cells
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    Suzhen Dong, Yale Duan, Yinghe Hu, Zheng Zhao · 2012 · Translational Neurodegeneration
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    Fitz, Nicholas F., Cronican, Andrea A., Saleem, Muzamil, Fauq, Abdul H., Chapman, Robert, Lefterov, Iliya, Koldamova, Radosveta · 2012 · The Journal of Neuroscience
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    Kysenius, Kai, Muggalla, Pranuthi, Mätlik, Kert, Arumäe, Urmas, Huttunen, Henri J. · 2012 · Cellular and Molecular Life Sciences
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    Boehm-Cagan, Anat, Michaelson, Daniel M. · 2014 · The Journal of Neuroscience
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    ElAli, Ayman, Rivest, Serge · 2016 · Brain, Behavior, and Immunity
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    Lisa M. McGinley, Osama Nezar Kashlan, Elizabeth S. Bruno, Kevin S. Chen, John M. Hayes, Samy R. Kashlan, Julia Raykin, Karl K. Johe, Geoffrey G. Murphy, Eva L. Feldman · 2018 · Scientific Reports
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    Shinohara, Mitsuru, Kanekiyo, Takahisa, Yang, Longyu, Linthicum, Duane, Shinohara, Motoko, Fu, Yuan, Price, Laura, Frisch‐Daiello, Jessica L., Han, Xianlin, Fryer, John D. et al. · 2016 · Annals of Neurology
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    Gandy, Sam, DeKosky, Steven T. · 2013 · Annual Review of Medicine
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    Kezhen Ge, Ying-Feng Mu, Miaoyan Liu, Zetai Bai, Zhao Liu, Deqin Geng, Fenglei Gao · 2022 · ACS Applied Materials & Interfaces
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    Liu, Chia-Chen, Murray, Melissa E., Li, Xia, Zhao, Na, Wang, Na, Heckman, Michael G., Shue, Francis, Martens, Yuka, Li, Yonghe, Raulin, Ana-Caroline et al. · 2021 · Science Translational Medicine
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    Johnson, Lance A., Olsen, Reid H.J., Merkens, Louise S., DeBarber, Andrea, Steiner, Robert D., Sullivan, Patrick M., Maeda, Nobuyo, Raber, Jacob · 2014 · Neurobiology of Disease
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