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PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors

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The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

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Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation

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PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.

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Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

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Impact of interferon-γ on hematopoiesis

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A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates

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Balance of MafB and PU. 1 specifies alternative macrophage or dendritic cell fate

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The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis

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Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage

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Granulocyte inducer C/EBPα inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions

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The genomic landscapes of inflammation

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Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia

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PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain

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PU.1 determines the self-renewal capacity of erythroid progenitor cells

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Novel Combinatorial Interactions of GATA-1, PU.1, and C/EBPε Isoforms Regulate Transcription of the Gene Encoding Eosinophil Granule Major Basic Protein

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Notch Signaling Induces Multilineage Myeloid Differentiation and Up-Regulates PU.1 Expression

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Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1

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Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

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Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia

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The Transcription Factor PU.1 is a Critical Regulator of Cellular Communication in the Immune System

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Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development

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Visualizing PU.1 activity during hematopoiesis

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C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

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Transcription Factors IRF8 and PU.1 Are Required for Follicular B Cell Development and BCL6‐driven Germinal Center Responses

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PU.1/Interferon Regulatory Factor Interactions; Mechanisms of Transcriptional Regulation

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PU.1 and Haematopoietic Cell Fate: Dosage Matters

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The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.

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Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1

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PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors

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PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

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Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks β-Selection

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AKT Induces Transcriptional Activity of PU.1 through Phosphorylation-mediated Modifications within Its Transactivation Domain

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A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1

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Stem Cell Fate Specification: Role of Master Regulatory Switch Transcription Factor PU.1 in Differential Hematopoiesis

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Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice

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Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures

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Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer’s disease

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Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity

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Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL-Induced Osteoclastogenesis

Izawa, N., Kurotaki, D., Nomura, S., Fujita, T., Omata, Y., Yasui, T., Hirose, J., Matsumoto, T., Saito, T., Kadono, Y., et al. (2019) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3689 · Cited by 40 · see citing works

Protein Acetylation Regulates Both PU.1 Transactivation and Igκ 3′ Enhancer Activity

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Spi-1/PU.1 participates in erythroleukemogenesis by inhibiting apoptosis in cooperation with Epo signaling and by blocking erythroid differentiation

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