Clinical trial of blood-brain barrier disruption by pulsed ultrasound

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MR-guided focused ultrasound liquid biopsy enriches circulating biomarkers in patients with brain tumors

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Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy

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Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound

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High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation

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Efficient Blood-Brain Barrier Opening in Primates with Neuronavigation-Guided Ultrasound and Real-Time Acoustic Mapping

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Ultrasound and microbubbles to beat barriers in tumors: Improving delivery of nanomedicine

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A Review of Phospholipid Encapsulated Ultrasound Contrast Agent Microbubble Physics

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Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas

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Single-cell analysis reveals effective siRNA delivery in brain tumors with microbubble-enhanced ultrasound and cationic nanoparticles

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Ultrasound technology and biomaterials for precise drug therapy

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Understanding the activity of antibody–drug conjugates in primary and secondary brain tumours

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From concept to early clinical trials: 30 years of microbubble-based ultrasound-mediated drug delivery research

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Focused Ultrasound‐Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging‐Guided Brain Tumor Treatment

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Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain

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Safety and Feasibility of Repeated and Transient Blood–Brain Barrier Disruption by Pulsed Ultrasound in Patients with Recurrent Glioblastoma

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Temporary disruption of the blood-brain barrier using an implantable ultrasound system for recurrent glioblastoma patients under IV carboplatin chemotherapy: initial phase 1/2a clinical trial observations

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A phase I/IIa study to evaluate the safety and efficacy of blood-brain barrier (BBB) opening with the SonoCloud-9 implantable ultrasound device in recurrent glioblastoma patients receiving IV carboplatin.

Idbaïh, A., Ducray, F., Stupp, R., Baize, N., Chinot, O. L., Groot, J. F. D., Guyotat, J., Sonabend, A. M., Meneï, P., Dufour, H., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.2021.39.15_suppl.2049 · Cited by 11

News in brief

(2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)30136-3

OS07.3.A Phase 1/2 clinical trial of blood-brain barrier opening with the SonoCloud-9 implantable ultrasound device in recurrent glioblastoma patients receiving IV carboplatin

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