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PqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa

Letizia, Morgana, Mellini, Marta, Fortuna, Alessandra, Visca, Paolo, Imperi, Francesco, Leoni, Livia, Rampioni, Giordano·2022·Microbiology Spectrum
DOI 10.1128/spectrum.00961-22
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Abstract

The ability of Pseudomonas aeruginosa to cause difficult-to-treat infections relies on its capacity to fine-tune the expression of multiple virulence traits via the las , rhl , and pqs QS systems. Both the pqs effector protein PqsE and the rhl transcriptional regulator RhlR are required for full production of key virulence factors in vitro and pathogenicity in vivo .

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Metadata

Authors
Letizia, M., Mellini, M., Fortuna, A., Visca, P., Imperi, F., Leoni, L., & Rampioni, G.
Venue
Microbiology Spectrum
Publisher
American Society for Microbiology
Published
2022-06-29
Volume
10
Issue
3
ISSN
2165-0497
DOI
10.1128/spectrum.00961-22
Cited by
67
References
0
Language
en
Licence
Funders
  • Italian Ministry of Education, University and Research (PRIN2017 - 20177J5Y3P, PRIN 2020 - 20208LLXEJ, PRIN 2020 - 202089LLEH)
  • Regione Lazio (Gruppi di Ricerca 2020 - POR A0375E0026)
  • Italian Cystic Fibrosis Research Foundation (FFC 17/2018)

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CoChat. (2026). Citation check: PqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa. https://app.cochat.ai/papers/10.1128/spectrum.00961-22
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Letizia, M., Mellini, M., Fortuna, A., Visca, P., Imperi, F., Leoni, L., & Rampioni, G. (2022). PqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa. Microbiology Spectrum. https://doi.org/10.1128/spectrum.00961-22

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