Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP

Ricquier, D., & Bouillaud, F. (2000) · Biochemical Journal · doi:10.1042/bj3450161 · Cited by 811

Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin

Gong, D., He, Y., Karas, M., & Reitman, M. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.39.24129 · Cited by 740

UCP3: An Uncoupling Protein Homologue Expressed Preferentially and Abundantly in Skeletal Muscle and Brown Adipose Tissue

Vidal‐Puig, A., Solanes, G., Grujić, D., Flier, J. S., & Lowell, B. B. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6740 · Cited by 711

Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization

Cousin, B., Cinti, S., Morroni, M., Raimbault, S., Ricquier, D., Pénicaud, L., & Casteilla, L. (1992) · Journal of Cell Science · doi:10.1242/jcs.103.4.931 · Cited by 665

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.

Guerra, C., Koza, R. A., Yamashita, H., Walsh, K., & Kozak, L. P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3155 · Cited by 635

Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats

Himms‐Hagen, J., Cui, J. Z., Danforth, E., Taatjes, D. J., Lang, S. S., Waters, B. L., & Claus, T. H. (1994) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1994.266.4.r1371 · Cited by 382

Brown adipose tissue in the parametrial fat pad of the mouse

Young, P., Arch, J. R. S., & Ashwell, M. (1984) · FEBS Letters · doi:10.1016/0014-5793(84)80822-4 · Cited by 377

Vascular Endothelial Growth Factor Is the Major Angiogenic Factor in Omentum: Mechanism of the Omentum-Mediated Angiogenesis

Zhang, Q.-X., Magovern, C. J., Mack, C. A., Budenbender, K. T., Ko, W., & Rosengart, T. K. (1997) · Journal of Surgical Research · doi:10.1006/jsre.1996.4983 · Cited by 365

Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.

Claffey, K. P., Wilkison, W. O., & Spiegelman, B. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42003-0 · Cited by 357

The uncoupling proteins, a review

Boss, O., Muzzin, P., & Giacobino, J.-P. (1998) · European Journal of Endocrinology · doi:10.1530/eje.0.1390001 · Cited by 263

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Wu, J., Boström, P., Sparks, L. M., Li, Y., Choi, J. H., Giang, A.-H., Khandekar, M. J., Virtanen, K. A., Nuutila, P., Schaart, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.05.016 · Cited by 3,406

Adipocyte differentiation from the inside out

Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607

What we talk about when we talk about fat

Rosen, E. D., & Spiegelman, B. M. (2014) · Cell · doi:10.1016/j.cell.2013.12.012 · Cited by 2,373

PRDM16 controls a brown fat/skeletal muscle switch

Seale, P., Bjork, B., Yang, W., Kajimura, S., Chin, S., Kuang, S., Scimè, A., Devarakonda, S., Conroe, H. M., Erdjument-Bromage, H., et al. (2008) · Nature · doi:10.1038/nature07182 · Cited by 2,347

Brown and beige fat: Development, function and therapeutic potential

Harms, M., & Seale, P. (2013) · Nature Medicine · doi:10.1038/nm.3361 · Cited by 2,328

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

Petrovic, N., Walden, T. B., Shabalina, I. G., Timmons, J. A., Cannon, B., & Nedergaard, J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.053942 · Cited by 1,263

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

Wang, Q. A., Tao, C., Gupta, R. K., & Scherer, P. E. (2013) · Nature Medicine · doi:10.1038/nm.3324 · Cited by 1,262

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

Seale, P., Conroe, H. M., Estall, J. L., Kajimura, S., Frontini, A., Ishibashi, J., Cohen, P., Cinti, S., & Spiegelman, B. M. (2010) · Journal of Clinical Investigation · doi:10.1172/jci44271 · Cited by 1,273

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

Choe, S. S., Huh, J. Y., Hwang, I. J., Kim, J. I., & Kim, J. B. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00030 · Cited by 1,206

Adipose tissue browning and metabolic health

Bartelt, A., & Heeren, J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.204 · Cited by 1,177

Transcriptional Control of Brown Fat Determination by PRDM16

Seale, P., Kajimura, S., Yang, W., Chin, S., Rohas, L. M., Uldry, M., Tavernier, G., Langin, D., & Spiegelman, B. M. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.001 · Cited by 1,174

Brown and Beige Fat: Physiological Roles beyond Heat Generation

Kajimura, S., Spiegelman, B. M., & Seale, P. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.09.007 · Cited by 1,028

Adaptive thermogenesis in adipocytes: Is beige the new brown?

Wu, J., Cohen, P., & Spiegelman, B. M. (2013) · Genes & Development · doi:10.1101/gad.211649.112 · Cited by 828

Bi-directional interconversion of brite and white adipocytes

Rosenwald, M., Perdikari, A., Rülicke, T., & Wolfrum, C. (2013) · Nature Cell Biology · doi:10.1038/ncb2740 · Cited by 833

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

Barbatelli, G., Murano, I., Madsen, L., Hao, Q., Jimenez, M., Kristiansen, K., Giacobino, J., Matteis, R. D., & Cinti, S. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00600.2009 · Cited by 788

Adipose tissue in control of metabolism

Luo, L., & Liu, M. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0211 · Cited by 764

Control of brown and beige fat development

Wang, W., & Seale, P. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.96 · Cited by 717

The adipose organ

Cinti, S. (2005) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.04.010 · Cited by 720

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

Sidossis, L. S., & Kajimura, S. (2015) · Journal of Clinical Investigation · doi:10.1172/jci78362 · Cited by 715

Adipose Tissue-Derived Factors: Impact on Health and Disease

Trujillo, M. E., & Scherer, P. E. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0033 · Cited by 624

White, Brown, Beige/Brite: Different Adipose Cells for Different Functions?

Giralt, M., & Villarroya, F. (2013) · Endocrinology · doi:10.1210/en.2013-1403 · Cited by 586

The cellular and functional complexity of thermogenic fat

Cohen, P., & Kajimura, S. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-021-00350-0 · Cited by 572

The role of mitochondria in the pathogenesis of type 2 diabetes

Patti, M.-E., & Corvera, S. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0027 · Cited by 551

The myokine irisin increases cortical bone mass

Colaianni, G., Cuscito, C., Mongelli, T., Pignataro, P., Buccoliero, C., Liu, P., Lü, P., Sartini, L., Comite, M. D., Mori, G., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516622112 · Cited by 521

Acquirement of brown fat cell features by human white adipocytes

Tiraby, C., Tavernier, G., Lefort, C., Larrouy, D., Bouillaud, F., Ricquier, D., & Langin, D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305235200 · Cited by 474

Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity

Hammarstedt, A., Gogg, S., Hedjazifar, S., Nerstedt, A., & Smith, U. (2018) · Physiological Reviews · doi:10.1152/physrev.00034.2017 · Cited by 462

The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes

Vitali, A., Murano, I., Zingaretti, M. C., Frontini, A., Ricquier, D., & Cinti, S. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m018846 · Cited by 487

Distribution and Development of Brown Adipocytes in the Murine and Human Adipose Organ

Frontini, A., & Cinti, S. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.03.004 · Cited by 484

A New Era in Brown Adipose Tissue Biology: Molecular Control of Brown Fat Development and Energy Homeostasis

Kajimura, S., & Saito, M. (2013) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021113-170252 · Cited by 439

Adipose-derived stem cells: Sources, potency, and implications for regenerative therapies

Si, Z., Wang, X., Sun, C., Kang, Y., Xu, J., Wang, X., & Hui, Y. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.108765 · Cited by 437

Adipose-derived stem cells: Implications in tissue regeneration

Tsuji, W. (2014) · World Journal of Stem Cells · doi:10.4252/wjsc.v6.i3.312 · Cited by 410

Transcriptional Regulation of Adipogenesis

de Sá, P. M., Richard, A. J., Hang, H., & Stephens, J. M. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160022 · Cited by 406

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat

Flachs, P., Horakova, O., Brauner, P., Rossmeisl, M., Pecina, P., Franssen-van Hal, N., Ruzickova, J., Sponarova, J., Drahota, Z., Vlcek, C., et al. (2005) · Diabetologia · doi:10.1007/s00125-005-1944-7 · Cited by 388

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

Nishino, N., Tamori, Y., Tateya, S., Kawaguchi, T., Shibakusa, T., Mizunoya, W., Inoue, K., Kitazawa, R., Kitazawa, S., Matsuki, Y., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34090 · Cited by 388

Transdifferentiation properties of adipocytes in the adipose organ

Cinti, S. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00183.2009 · Cited by 379

Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease

Betz, M. J., & Enerbäck, S. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.132 · Cited by 373

The adipose organ at a glance

Cinti, S. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.009662 · Cited by 370

Beige adipocyte maintenance is regulated by autophagy-induced mitochondrial clearance

Altshuler-Keylin, S., Shinoda, K., Hasegawa, Y., Ikeda, K., Hong, H., Kang, Q., Yang, Y., Perera, R. M., Debnath, J., & Kajimura, S. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.08.002 · Cited by 349

TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis

Li, Y., Kleiner, S., Wu, J., Sah, R., Gupta, R. K., Banks, A. S., Cohen, P., Khandekar, M. J., Boström, P., Mepani, R. J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.08.034 · Cited by 353

Deconstructing adipogenesis induced by β3-Adrenergic receptor activation with single-cell expression profiling

Burl, R. B., Ramseyer, V. D., Rondini, E. A., Pique-Regi, R., Lee, Y.-H., & Granneman, J. G. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.05.025 · Cited by 332

Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice

Vishvanath, L., MacPherson, K. A., Hepler, C., Wang, Q. A., Shao, M., Spurgin, S. B., Wang, M. Y., Kusminski, C. M., Morley, T. S., & Gupta, R. K. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.10.018 · Cited by 326

The secretory function of adipocytes in the physiology of white adipose tissue

Wang, P., Mariman, E., Renes, J., & Keijer, J. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21386 · Cited by 318

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

Qian, S., Tang, Y., Li, X., Liu, Y., Zhang, Y.-Y., Huang, H.-Y., Xue, R.-D., Yu, H.-Y., Guo, L., Gao, H.-D., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215236110 · Cited by 320

Metabolic and cellular plasticity in white adipose tissue I: effects of β3-adrenergic receptor activation

Granneman, J. G., Li, P., Zhu, Z., & Lu, Y. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00009.2005 · Cited by 298

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC

Rubio‐Cabezas, O., Puri, V., Murano, I., Saudek, V., Semple, R. K., Dash, S., Hyden, C. S. S., Bottomley, W. E., Vigouroux, C., Magré, J., et al. (2009) · EMBO Molecular Medicine · doi:10.1002/emmm.200900037 · Cited by 294

Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling

Fabbiano, S., Suárez-Zamorano, N., Rigo, D., Veyrat‐Durebex, C., Đokić, A., Colin, D., & Trajkovski, M. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.07.023 · Cited by 296

Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat

Xue, B., Rim, J.-S., Hogan, J. C., Coulter, A. A., Koza, R. A., & Kozak, L. P. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m600287-jlr200 · Cited by 288

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

Hansen, J. B., Jørgensen, C., Petersen, R. K., Hallenborg, P., De Matteis, R., Bøye, H. A., Petrovic, N., Enerbäck, S., Nedergaard, J., Cinti, S., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0301964101 · Cited by 287

Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair

Shook, B. A., Wasko, R. R., Mano, O., Rutenberg-Schoenberg, M., Rudolph, M. C., Zirak, B., Rivera-Gonzalez, G. C., López‐Giráldez, F., Zarini, S., Rezza, A., et al. (2020) · Cell stem cell · doi:10.1016/j.stem.2020.03.013 · Cited by 295

Cellular and molecular effects ofn−3 polyunsaturated fatty acids on adipose tissue biology and metabolism

Flachs, P., Rossmeisl, M., Bryhn, M., & Kopecký, J. (2008) · Clinical Science · doi:10.1042/cs20070456 · Cited by 293

UCP1-independent Thermogenesis in White Adipose Tissue of Cold-acclimated Ucp1 -/- Mice

Ukropec, J., Anunciado, R. V. P., Ravussin, Y., Hulver, M. W., & Kozak, L. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m606114200 · Cited by 293

Adiposity and Insulin Resistance in Humans: The Role of the Different Tissue and Cellular Lipid Depots

HOCKING, S. L., Samocha‐Bonet, D., Milner, K., Greenfield, J. R., & Chisholm, D. J. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1041 · Cited by 295

MECHANISMS IN ENDOCRINOLOGY: White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ

Giordano, A., Smorlesi, A., Frontini, A., Barbatelli, G., & Cinti, S. (2014) · European Journal of Endocrinology · doi:10.1530/eje-13-0945 · Cited by 298

Cellular origins of cold‐induced brown adipocytes in adult mice

Lee, Y., Petkova, A. P., Konkar, A. A., & Granneman, J. G. (2014) · The FASEB Journal · doi:10.1096/fj.14-263038 · Cited by 291

Mechanistic Links Between Obesity, Diabetes, and Blood Pressure: Role of Perivascular Adipose Tissue

Saxton, S. N., Clark, B., Withers, S., Eringa, E. C., & Heagerty, A. M. (2019) · Physiological Reviews · doi:10.1152/physrev.00034.2018 · Cited by 290

Pharmacological and nutritional agents promoting browning of white adipose tissue

Bonet, M. L., Oliver, P., & Palou, A. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2012.12.002 · Cited by 286

Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells

Park, A. (2014) · World Journal of Stem Cells · doi:10.4252/wjsc.v6.i1.33 · Cited by 291

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

Lee, Y., Petkova, A. P., & Granneman, J. G. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.08.003 · Cited by 293

The adipocyte as an endocrine organ in the regulation of metabolic homeostasis

Harwood, H. J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.12.010 · Cited by 282

Subcutaneous fat in normal and diseased states

Avram, M. M., Avram, A. S., & James, W. D. (2007) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2006.06.022 · Cited by 269

Lipid droplet-organelle interactions; sharing the fats

Murphy, S., Martin, S., & Parton, R. G. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.07.004 · Cited by 265

MyomiR-133 regulates brown fat differentiation through Prdm16

Trajkovski, M., Ahmed, K., Esau, C., & Stoffel, M. (2012) · Nature Cell Biology · doi:10.1038/ncb2612 · Cited by 263

Molecular Mechanisms of Adipogenesis: The Anti-adipogenic Role of AMP-Activated Protein Kinase

Ahmad, B., Serpell, C. J., Fong, I. L., & Wong, E. H. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00076 · Cited by 260

Brown fat biology and thermogenesis

Richard, D. (2010) · Frontiers in bioscience · doi:10.2741/3786 · Cited by 251

Fat cells directly sense temperature to activate thermogenesis

Li, Y., Wu, J., Cohen, P., Kazak, L., Khandekar, M. J., Jedrychowski, M. P., Zeng, X., Gygi, S. P., & Spiegelman, B. M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310261110 · Cited by 250

Remodeling of White Adipose Tissue after Retinoic Acid Administration in Mice

Mercader, J., Ribot, J., Murano, I., Felipe, F., Cinti, S., Bonet, M. L., & Palou, A. (2006) · Endocrinology · doi:10.1210/en.2006-0760 · Cited by 244

Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells

Mori, M., Nakagami, H., Rodriguez-Araujo, G., Nimura, K., & Kaneda, Y. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001314 · Cited by 243

Mitochondria in White, Brown, and Beige Adipocytes

Čedíková, M., Kripnerová, M., Dvořáková, J., Pitule, P., Grundmanova, M., Babuška, V., Müllerová, D., & Kuncová, J. (2016) · Stem Cells International · doi:10.1155/2016/6067349 · Cited by 249

Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders

Kim, S. H., & Plutzky, J. (2016) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2016.40.1.12 · Cited by 240

Convertible visceral fat as a therapeutic target to curb obesity

Giordano, A., Frontini, A., & Cinti, S. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.31 · Cited by 241

Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

Machado, S. A., Pasquarelli-do-Nascimento, G., da Silva, D. S., Farias, G. R., Santos, I. D. O., Baptista, L. B., & Magalhães, K. G. (2022) · Nutrition & Metabolism · doi:10.1186/s12986-022-00694-0 · Cited by 239

The adipose organ: morphological perspectives of adipose tissues

Cinti, S. (2001) · Proceedings of The Nutrition Society · doi:10.1079/pns200192 · Cited by 235

Brown adipose tissue and thermogenesis

Fenzl, A., & Kiefer, F. W. (2014) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2014-0022 · Cited by 239

Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling

Bertholet, A. M., Kazak, L., Chouchani, E. T., Bogaczyńska, M. G., Paranjpe, I., Wainwright, G. L., Bétourné, A., Kajimura, S., Spiegelman, B. M., & Kirichok, Y. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.03.002 · Cited by 225

Sympathetic innervation of white adipose tissue and its regulation of fat cell number

Bowers, R. R., Festuccia, W. T., Song, C. K., Shi, H., Migliorini, R. H., & Bartness, T. J. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00558.2003 · Cited by 221

Induction of Adipose Tissue Browning as a Strategy to Combat Obesity

Kuryłowicz, A., & Puzianowska-Kuźnicka, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176241 · Cited by 219

Adipose tissue plasticity from WAT to BAT and in between

Lee, Y., Mottillo, E. P., & Granneman, J. G. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.05.011 · Cited by 236

Emerging Complexities in Adipocyte Origins and Identity

Sánchez-Gurmaches, J., Hung, C., & Guertin, D. A. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.01.004 · Cited by 225

Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ.

Cinti, S. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03344046 · Cited by 213

Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

Poher, A.-L., Altirriba, J., Veyrat‐Durebex, C., & Rohner‐Jeanrenaud, F. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00004 · Cited by 219

White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma

Frontini, A., Vitali, A., Perugini, J., Murano, I., Romiti, C., Ricquier, D., Guerrieri, M., & Cinti, S. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.02.005 · Cited by 218

Adult Epicardial Fat Exhibits Beige Features

Sacks, H. S., Fain, J. N., Bahouth, S. W., Ojha, S., Frontini, A., Budge, H., Cinti, S., & Symonds, M. E. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1265 · Cited by 218

Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ

Murano, I., Barbatelli, G., Giordano, A., & Cinti, S. (2009) · Journal of Anatomy · doi:10.1111/j.1469-7580.2008.01001.x · Cited by 208

White adipose tissue contributes to UCP1-independent thermogenesis

Granneman, J. G., Burnazi, M., Zhu, Z., & Schwamb, L. A. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00197.2003 · Cited by 205

Gestational Hypoxia and Developmental Plasticity

Ducsay, C. A., Goyal, R., Pearce, W. J., Wilson, S. M., Hu, X., & Zhang, L. (2018) · Physiological Reviews · doi:10.1152/physrev.00043.2017 · Cited by 208

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α

Scimè, A., Grenier, G., Huh, M. S., Gillespie, M. A., Bevilacqua, L., Harper, M.-E., & Rudnicki, M. A. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.10.002 · Cited by 199

BAT: a new target for human obesity?

Frühbeck, G., Becerril, S., Sáinź, N., Garrastachu, P., & García‐Velloso, M. J. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.05.003 · Cited by 198

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity

Madsen, L., Pedersen, L. M., Lillefosse, H. H., Fjære, E., Brønstad, I., Hao, Q., Petersen, R. K., Hallenborg, P., Ma, T., Matteis, R. D., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011391 · Cited by 204

Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats

Jiménez‐Aranda, A., Fernández‐Vázquez, G., Campos, D., Tassi, M., Velasco‐Perez, L., Tan, D. X., Reiter, R. J., & Agil, A. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12089 · Cited by 193

Adipose Organ Development and Remodeling

Cinti, S. (2018) · Comprehensive physiology · doi:10.1002/cphy.c170042 · Cited by 197

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

Mori, M. A., Thomou, T., Boucher, J., Lee, K. Y., Lallukka, S., Kim, J. K., Torriani, M., Yki‐Järvinen, H., Grinspoon, S. K., Cypess, A. M., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci73468 · Cited by 189

The adipose organ: white‐brown adipocyte plasticity and metabolic inflammation

Smorlesi, A., Frontini, A., Giordano, A., & Cinti, S. (2012) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01039.x · Cited by 189

Learning New Tricks from Old Dogs: β-Adrenergic Receptors Teach New Lessons on Firing Up Adipose Tissue Metabolism

Collins, S., Cao, W., & Robidoux, J. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0193 · Cited by 179

Regulatory circuits controlling white versus brown adipocyte differentiation

Hansen, J. B., & Kristiansen, K. (2006) · Biochemical Journal · doi:10.1042/bj20060402 · Cited by 178

White-to-brown metabolic conversion of human adipocytes by JAK inhibition

Moisan, A., Lee, Y., Zhang, J. D., Hudak, C. S. S., Meyer, C. A., Prummer, M., Zoffmann, S., Truong, H., Ebeling, M., Kiialainen, A., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3075 · Cited by 182

Brown and Beige Adipose Tissues in Health and Disease

Rui, L. (2017) · Comprehensive physiology · doi:10.1002/cphy.c170001 · Cited by 186

Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis

Müller, G. A., Schneider, M., Biemer‐Daub, G., & Wied, S. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.03.013 · Cited by 176

Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes

Lee, J., Takahashi, N., Yasubuchi, M., Kim, Y., Hashizaki, H., Kim, M., Sakamoto, T., Goto, T., & Kawada, T. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00010.2011 · Cited by 185

Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction

Higami, Y., Pugh, T. D., Page, G. P., Allison, D. B., Prolla, T. A., & Weindruch, R. (2004) · The FASEB Journal · doi:10.1096/fj.03-0678fje · Cited by 173

Brown adipose tissue: Development, metabolism and beyond

Schulz, T. J., & Tseng, Y.-H. (2013) · Biochemical Journal · doi:10.1042/bj20130457 · Cited by 173

Transformation of some unilocular (UL) into multilocular (ML) adipocytes in white adipose tissue (WAT) of CL316,243 (CL)-treated rats.

a, M., C, Z. M., Ceresi, E., Cancello, R., Cinti, S., Himms Hagen, J., & Matteis, R. D. (1999) · CINECA IRIS Institutional Research information system (University of Urbino)

Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a β3-adrenoceptor agonist

Ghorbani, M., Claus, T. H., & Himms-Hagen, J. (1997) · Biochemical Pharmacology · doi:10.1016/s0006-2952(97)00162-7 · Cited by 195

Apparent histological changes of adipocytes after treatment with CL 316,243, a ß-3-adrenergic receptor agonist

Ghorbani, M., Teimourian, S., Farzad, R., & Asl, N. N. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s73891 · Cited by 15

Metabolic and cellular plasticity in white adipose tissue I: effects of β3-adrenergic receptor activation

Granneman, J. G., Li, P., Zhu, Z., & Lu, Y. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00009.2005 · Cited by 298

Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats

Ghorbani, M., & Himms‐Hagen, J. (1997) · International Journal of Obesity · doi:10.1038/sj.ijo.0800432 · Cited by 250