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Cited by 401

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Effect of muscle mass decrease on age-related BMR changes

Tzankoff, S. P., Norris, A. H.·1977·Journal of Applied Physiology

Abstract

The long known and often studied decrease in basal metabolic rate (BMR) with age was recently shown related to changes in the proportion of lean-to-fat tissue mass in the body. Earlier studies from this laboratory showed the decline in basal 0, consumption (basal 00,) to be accounted for by a decline in lean body mass (LBM). The purpose of the present study was to identify and account for that component of the lean body responsible for the age-related decrease in basal vo, in 959 participants in the Baltimore Longitudinal Study aged from 20 to 97 yr, An age-independent linear relation was found between paired values of basal voz, a measure of total metabolic activity, and 24-h creatinine excretion, a measure proportional to skeletal muscle mass. The relation is quanti-fied by basal Tie, = 99.1 + 0.079 (creatinine excretion), where basal vo, is expressed in mllmin (STPD) and creatinine excre-

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Crossref · 10.1152/jappl.1977.43.6.1001

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Metadata

Authors
Tzankoff, S. P., & Norris, A. H.
Venue
Journal of Applied Physiology
Published
1977-12-01
Volume
43
Issue
6
Pages
1001-1006
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
OpenAlex
W1933184123
Cited by
401
References
0
FWCI
1.29
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.