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Overexpression of hypoxia-inducible factor HIF-1α predicts early relapse in breast cancer: Retrospective study in a series of 745 patients

Dalès, J.-P., Garcia, S., Meunier-Carpentier, S., Andrac, L., Haddad, O., Lavaut, M., Allasia, C., Bonnier, P., & Charpin, C. (2005) · International Journal of Cancer · doi:10.1002/ijc.20984 · Cited by 263

BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death Induced by Hypoxia-inducible Factor 1α

Kim, J., Ahn, H., Ryu, J.-H., Suk, K., & Park, J.-H. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030613 · Cited by 261

Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy

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Glycogen Synthase Kinase 3 Phosphorylates Hypoxia-Inducible Factor 1α and Mediates Its Destabilization in a VHL-Independent Manner

Flügel, D., Görlach, A., Michiels, C., & Kietzmann, T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00015-07 · Cited by 258

Protein damage, repair and proteolysis

Chondrogianni, N., Petropoulos, I., Grimm, S., Georgila, K., Catalgol, B., Friguet, B., Grune, T., & Gonos, E. S. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.09.001 · Cited by 271

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

Masamune, A., Kikuta, K., Watanabe, T., Satoh, K., Hirota, M., & Shimosegawa, T. (2008) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.90356.2008 · Cited by 264

Metabolic reprogramming and therapeutic resistance in primary and metastatic breast cancer

Liu, S., Zhang, X., Wang, W., Li, X., Sun, X., Zhao, Y., Wang, Q., Li, Y., Hu, F., & Ren, H. (2024) · Molecular Cancer · doi:10.1186/s12943-024-02165-x · Cited by 300

Neuroprotective role of astrocytes in cerebral ischemia: Focus on ischemic preconditioning

Trendelenburg, G., & Dirnagl, U. (2005) · Glia · doi:10.1002/glia.20204 · Cited by 258

HIF-1: a key mediator in hypoxia (Review)

Adams, J., DiFazio, L. T., Rolandelli, R. H., Luján, J., Haskó, G., Csóka, B., Selmeczy, Z., & Németh, Z. H. (2009) · Acta Physiologica Hungarica · doi:10.1556/aphysiol.96.2009.1.2 · Cited by 152

Hypoxia, HIF-1, and the Pathophysiologi of Common Human Diseases

Semenza, G. L., Agani, F., Feldser, D., Lyer, N., Kotch, L., Laughner, E., & Yu, 1. (2006) · Advances in Experimental Medicine and Biology · doi:10.1007/0-306-46825-5_12 · Cited by 241

Regulation of Mammalian O 2 Homeostasis by Hypoxia-Inducible Factor 1

Semenza, G. L. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.551 · Cited by 1,914

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

Semenza, G. L. (2009) · Physiology · doi:10.1152/physiol.00045.2008 · Cited by 926

Life with Oxygen

Semenza, G. L. (2007) · Science · doi:10.1126/science.1147949 · Cited by 706