Serum triglycerides as a risk factor for cardiovascular diseases in the Asia-Pacific region.
Abstract
BACKGROUND: The importance of serum triglyceride levels as a risk factor for cardiovascular diseases is uncertain. METHODS AND RESULTS: We performed an individual participant data meta-analysis of prospective studies conducted in the Asia-Pacific region. Cox models were applied to the combined data from 26 studies to estimate the overall and region-, sex-, and age-specific hazard ratios for major cardiovascular diseases by fifths of triglyceride values. During 796,671 person-years of follow-up among 96,224 individuals, 670 and 667 deaths as a result of coronary heart disease (CHD) and stroke, respectively, were recorded. After adjustment for major cardiovascular risk factors, participants grouped in the highest fifth of triglyceride levels had a 70% (95% CI, 47 to 96) greater risk of CHD death, an 80% (95% CI, 49 to 119) higher risk of fatal or nonfatal CHD, and a 50% (95% CI, 29% to 76%) increased risk of fatal or nonfatal stroke compared with those belonging to the lowest fifth. The association between triglycerides and CHD death was similar across subgroups defined by ethnicity, age, and sex. CONCLUSIONS: Serum triglycerides are an important and independent predictor of CHD and stroke risk in the Asia-Pacific region. These results may have clinical implications for cardiovascular risk prediction and the use of lipid-lowering therapy.
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Several meta-analyses from studies performed in the general population have shown a modest but independent effect of triglycerides on CVD.
“Several meta-analyses from studies performed in the general population have shown a modest but independent effect of triglycerides on CVD.”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [134]
The Discussion (page unavailable) calls this work a meta-analysis of Asia-Pacific cohorts and reports an association between triglycerides and cardiovascular risk independent of other measured risk factors. It also mentions one previous meta-analysis with a similar finding. The paper therefore supports the independent association, but not the broader claim that several meta-analyses of general-population studies have shown it. (LLM, conf=0.86)
Experimental — accuracy not yet measuredA meta-analysis based on Asian and Pacific populations calculated a relative risk for coronary heart disease, adjusted for several established risk factors, of 1.80 (95% CI, 1.49-2.19), comparing subjects in the top with those in the bottom quintile of triglyceride levels.
“This latter meta-analysis calculated a relative risk for coronary heart disease, adjusted for several established risk factors, of 1.80 (95% CI, 1.49 -2.19), comparing subjects in the top with those in the bottom quintile of triglyceride levels.”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [134]
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Experimental — accuracy not yet measuredHigh TG is associated with CAD risk in Europe, the US, Asia, Oceania, and Japan.
“There have been numerous reports on the association between a high TG level and the risk for CAD not just in Europe and the US86), but also in Asia, Oceania87) and even in Japan46, 78, 88–91).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [86]
The association between TG and CAD was observed even with normal HDL-C.
“Despite a normal range of HDL-C, the association between TG and CAD was still observed in several of these studies86–89).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [86]
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Cites
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Analysis of Incomplete Multivariate Data
Schafer, J. L. (1997) · doi:10.1201/9781439821862 · Cited by 6,012 · see citing works
Analysis of Incomplete Multivariate Data
Booth, D. E., & Schafer, J. L. (2000) · Technometrics · doi:10.2307/1271466 · Cited by 5,627 · see citing works
Hokanson, J. E., & Austin, M. A. (1996) · Journal of Cardiovascular Risk · doi:10.1097/00043798-199604000-00014 · Cited by 1,706 · see citing works
Stampfer, M. J. (1996) · JAMA · doi:10.1001/jama.1996.03540110036029 · Cited by 1,085 · see citing works
Clarke, R., Shipley, M. J., Lewington, S., Youngman, L. D., Collins, R., Marmot, M. G., & Peto, R. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a010013 · Cited by 879 · see citing works
Epidemiology: Study Design and Data Analysis
(2006) · Technometrics · doi:10.1198/tech.2006.s407 · Cited by 789 · see citing works
Plasma triglyceride and coronary heart disease
Austin, M. A. (1991) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.11.1.2 · Cited by 697 · see citing works
Triglyceride Concentration and Ischemic Heart Disease
Jeppesen, J., Hein, H. O., Suadicani, P., & Gyntelberg, F. (1998) · Circulation · doi:10.1161/01.cir.97.11.1029 · Cited by 673 · see citing works
Fasting Triglycerides, High-Density Lipoprotein, and Risk of Myocardial Infarction
Gaziano, J. M., Hennekens, C. H., O’Donnell, C. J., Breslow, J. L., & Buring, J. E. (1997) · Circulation · doi:10.1161/01.cir.96.8.2520 · Cited by 602 · see citing works
Postprandial lipoproteins and progression of coronary atherosclerosis
Karpe, F., Steiner, G. A., Uffelman, K. D., Olivecrona, T., & Hamsten, A. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90085-x · Cited by 486 · see citing works
ROSNER, B. A., Spiegelman, D. L., & Willett, W. C. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115715 · Cited by 464 · see citing works
Assmann, G., Schulte, H., & von Eckardstein, A. (1996) · The American Journal of Cardiology · doi:10.1016/s0002-9149(96)00159-2 · Cited by 445 · see citing works
Easton, D. F., Peto, J., & Babiker, A. G. (1991) · Statistics in Medicine · doi:10.1002/sim.4780100703 · Cited by 434 · see citing works
Plasma Triglyceride Level and Mortality from Coronary Heart Disease
Criqui, M. H., HEISS, G. M., Cohn, R. D., Cowan, L. D., Suchindran, C., Bangdiwala, S. I., Kritchevsky, S., Jacobs, D. R., O'Grady, H. K., & DAVIS, C. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281702 · Cited by 418 · see citing works
Lindenstrom, E., Boysen, G., & Nyboe, J. (1994) · BMJ · doi:10.1136/bmj.309.6946.11 · Cited by 370 · see citing works
Serum Triglycerides and Risk of Coronary Heart Disease among Japanese Men and Women
Iso, H., Naito, Y., Sato, S., Kitamura, A., Okamura, T., Sankai, T., Shimamoto, T., Iida, M., & Komachi, Y. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.5.490 · Cited by 325 · see citing works
Incidence of the Major Stroke Subtypes
Thrift, A. G., Dewey, H. M., Macdonell, R. A. L., McNeil, J. J., & Donnan, G. A. (2001) · Stroke · doi:10.1161/01.str.32.8.1732 · Cited by 302 · see citing works
Barzi, F. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh175 · Cited by 263 · see citing works
Fibrinogen and coronary heart disease--what does it mean?
Assmann, G., Schulte, H., Funke, H., & von Eckardstein, A. (1998) · PubMed · Cited by 256 · see citing works
Risk Factors for Ischemic Stroke
Simons, L. A., McCallum, J. C., Friedlander, Y., & Simons, J. (1998) · Stroke · doi:10.1161/01.str.29.7.1341 · Cited by 256 · see citing works
HDL-Cholesterol, Total Cholesterol, and the Risk of Stroke in Middle-Aged British Men
Wannamethee, S. G., Shaper, A. G., & Ebrahim, S. (2000) · Stroke · doi:10.1161/01.str.31.8.1882 · Cited by 220 · see citing works
Bainton, D., Miller, N., Bolton, C., YARNELL, J. W. G., Sweetnam, P. M., Baker, I. A., Lewis, B., & Elwood, P. C. (1992) · Heart · doi:10.1136/hrt.68.7.60 · Cited by 210 · see citing works
Lipoprotein Subclasses in the Monitored Atherosclerosis Regression Study (MARS)
Mack, W. J., Krauss, R. M., & Hodis, H. N. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.5.697 · Cited by 173 · see citing works
Cambien, F., Jacqueson, A., Richard, J. L., Warnet, J., Ducimetière, P., & Claude, J. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114435 · Cited by 162 · see citing works
Tanne, D., Koren-Morag, N., Graff, E., & Goldbourt, U. (2001) · Circulation · doi:10.1161/hc4901.100384 · Cited by 158 · see citing works
Cardiovascular epidemiology in the Asia–Pacific region
Khor, G. L. (2001) · Asia Pacific Journal of Clinical Nutrition · doi:10.1111/j.1440-6047.2001.00230.x · Cited by 152 · see citing works
Serum Lipids and Incidence of Coronary Heart Disease
Frost, P. H., Davis, B. R., Burlando, A. J., Curb, J. D., Guthrie, G. P., Isaacsohn, J. L., Wassertheil-Smoller, S. W., Wilson, A. C., & Stamler, J. (1996) · Circulation · doi:10.1161/01.cir.94.10.2381 · Cited by 148 · see citing works
Hellerstein, M. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200202000-00006 · Cited by 141 · see citing works
Elevated Serum Triglyceride Levels and Long-Term Mortality in Patients With Coronary Heart Disease
Haim, M., Benderly, M., Brunner, D., Behar, S., Graff, E., Reicher-Reiss, H., & Goldbourt, U. (1999) · Circulation · doi:10.1161/01.cir.100.5.475 · Cited by 138 · see citing works
Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women
Njølstad, I., Arnesen, E., & Lund‐Larsen, P. G. (1996) · Circulation · doi:10.1161/01.cir.94.11.2877 · Cited by 133 · see citing works
Austin, M. A., Rodriguez, B. L., McKnight, B., McNeely, M. J., Edwards, K. L., Curb, J. D., & Sharp, D. S. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00956-5 · Cited by 129 · see citing works
Urban-rural differences in the prevalence of coronary heart disease and its risk factors in Delhi.
Chadha, S. L., Gopinath, N., & Shekhawat, S. (1997) · Europe PMC (PubMed Central) · Cited by 128 · see citing works
RETEST RELIABILITY OF PLASMA CHOLESTEROL AND TRIGLYCERIDE
Jacobs, D. R., & Barrett-Connor, E. L. (1982) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113490 · Cited by 128 · see citing works
Postprandial state and atherosclerosis
Ebenbichler, C. F., Kirchmair, R., Egger, C., & Patsch, J. R. (1995) · Current Opinion in Lipidology · doi:10.1097/00041433-199510000-00008 · Cited by 116 · see citing works
Cardiovascular epidemiology in the Asia-Pacific region
Khor, G. L. (2001) · Asia Pacific Journal of Clinical Nutrition · doi:10.1046/j.1440-6047.2001.00230.x · Cited by 100 · see citing works
Demographic Study of First-ever Stroke and Acute Myocardial Infarction in Okinawa, Japan.
Kimura, Y., Takishita, S., Muratani, H., Kinjo, K., Shinzato, Y., Muratani, A., & Fukiyama, K. (1998) · Internal Medicine · doi:10.2169/internalmedicine.37.736 · Cited by 76 · see citing works
Sekikawa, A. M. (1999) · International Journal of Epidemiology · doi:10.1093/ije/28.6.1044 · Cited by 73 · see citing works
Plasma lipid profiles and epidemiology of atherosclerotic diseases in Taiwan — a unique experience
Pan, W., & Chiang, B. N. (1995) · Atherosclerosis · doi:10.1016/0021-9150(95)05616-5 · Cited by 58 · see citing works
Serum Lipids and their Correlates in Chinese Urban and Rural Populations of Beijing and Guangzhou
Tao, S., Li, Y., Xiao, Z., Cen, R., Zhang, H., ZHUO, Y., Zhou, B., CHEN, P., Li, Y., Liao, Y., et al. (1992) · International Journal of Epidemiology · doi:10.1093/ije/21.5.893 · Cited by 51 · see citing works
Triglyceride and coronary heart disease mortality in a 24-year follow-up study in Xi'an, China
He, Y., Lam, T. H., Li, L. S., Li, L. S., He, S. F., & Liang, B. Q. (2003) · Annals of Epidemiology · doi:10.1016/s1047-2797(03)00069-3 · Cited by 44 · see citing works
Egger, M., Smith, G. D., Pfluger, D. H., Altpeter, E., & Elwood, P. C. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(98)00300-1 · Cited by 42 · see citing works
Avins, A. L., & Browner, W. S. (1998) · JAMA · doi:10.1001/jama.279.6.445 · Cited by 37 · see citing works
Zhang, X. H., MacMahon, S. W., Rodgers, A. J., et al. (1999) · Cited by 36 · see citing works
Stroke in China (Sino-MONICA-Beijing Study) 1984–1986
Chen, D., Román, G. C., Wu, G.-X., et al. (1992) · Neuroepidemiology · doi:10.1159/000110902 · Cited by 36 · see citing works
A prevalence survey of lipids abnormalities of rural area in Amphoe Phon, Khon Kaen.
Bhuripanyo, K., Tatsanavivat, P., Matrakool, B., et al. (1993) · PubMed · Cited by 19 · see citing works
Heffernan, S. J., James, V. J., Zilkens, R., et al. (1996) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(96)01335-6 · Cited by 14 · see citing works
Neurosonology in Cerebral Ischemia: Future Application of Transcranial Doppler in Acute Stroke
Egido, J. A., & Sánchez, C. (2001) · Cerebrovascular Diseases · doi:10.1159/000049121 · Cited by 13 · see citing works
Community-based epidemiologic study on atherosclerotic cardiovascular risk factors
Park, Y., Lee, H., Koh, C., et al. (1996) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(96)90010-8 · Cited by 8 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Bainton D, Miller NE, Bolton CH, et al. Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men. Br Heart J. 1992;68:60 -66.
Cited by
Sorted by citations
Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., et al. (2014) · Stroke · doi:10.1161/str.0000000000000046 · Cited by 2,650 · see citing works
Sarwar, N., Danesh, J., Eiriksdottir, G., Sigurdsson, G., Wareham, N., Bingham, S., Boekholdt, S. M., Khaw, K.-T., & Gudnason, V. (2007) · Circulation · doi:10.1161/circulationaha.106.637793 · Cited by 1,408 · see citing works
Goldstein, L. B., Bushnell, C. D., Adams, R. J., Appel, L. J., Braun, L. T., Chaturvedi, S., Creager, M. A., Culebras, A., Eckel, R. H., Hart, R. G., et al. (2011) · Stroke · doi:10.1161/str.0b013e3181fcb238 · Cited by 1,306 · see citing works
Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline
Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887 · see citing works
Kinoshita, M., Yokote, K., Arai, H., Iida, M., Ishigaki, Y., Ishibashi, S., Umemoto, S., Egusa, G., Ohmura, H., Okamura, T., et al. (2018) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2017 · Cited by 813 · see citing works
Nonfasting triglycerides and risk of ischemic stroke in the general population
Freiberg, J. J. (2008) · JAMA · doi:10.1001/jama.2008.621 · Cited by 542 · see citing works
Niacin and fibrates in atherogenic dyslipidemia: pharmacotherapy to reduce cardiovascular risk
Chapman, M. J., Redfern, J. S., McGovern, M. E., & Giral, P. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.01.008 · Cited by 227 · see citing works
Hypertriglyceridemia and its pharmacologic treatment among US adults.
Ford, E. S., Li, C., Zhao, G., Pearson, W. S., & Mokdad, A. H. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2008.599 · Cited by 214 · see citing works
Sone, H., Tanaka, S., Tanaka, S., Iimuro, S., Oida, K., Yamasaki, Y., Oikawa, S., Ishibashi, S., Katayama, S., Ohashi, Y., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0622 · Cited by 201 · see citing works
Paniagua, J. A. (2016) · World Journal of Diabetes · doi:10.4239/wjd.v7.i19.483 · Cited by 197 · see citing works
Postprandial hypertriglyceridemia as a coronary risk factor
Borén, J., Matikainen, N., Adiels, M., & Taskinen, M.-R. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.01.015 · Cited by 182 · see citing works
Changes in triglyceride levels and risk for coronary heart disease in young men.
Tirosh, A., Rudich, A., Shochat, T., Tekes-Manova, D., Israeli, E., Henkin, Y., Kochba, I., & Shai, I. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-6-200709180-00007 · Cited by 151 · see citing works
Triglycerides as vascular risk factors: new epidemiologic insights.
Kannel, W. B., & Vasan, R. S. (2009) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e32832c1284 · Cited by 149 · see citing works
Stalenhoef, A. F., & de Graaf, J. (2008) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328304b63c · Cited by 121 · see citing works
Ridker, P. M. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.097907 · Cited by 114 · see citing works
Iso, H., Imano, H., Yamagishi, K., Ohira, T., Cui, R., Noda, H., Sato, S., Kiyama, M., Okada, T., Hitsumoto, S., et al. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.08.028 · Cited by 104 · see citing works
Nichols, G. A., Philip, S., Reynolds, K., Granowitz, C. B., & Fazio, S. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-00470 · Cited by 102 · see citing works
Murad, M. H., Hazem, A., Coto-Yglesias, F., Dzyubak, S., Gupta, S., Bancos, I., Lane, M. A., Erwin, P. J., Berglund, L., Elraiyah, T., et al. (2012) · BMC Endocrine Disorders · doi:10.1186/1472-6823-12-2 · Cited by 87 · see citing works
Kim, S.-M., Lim, S.-M., Yoo, J.-A., Woo, M.-J., & Cho, K.-H. (2015) · Food & Function · doi:10.1039/c5fo00738k · Cited by 69 · see citing works
Bashir, B., Schofield, J., Downie, P., France, M., Ashcroft, D. M., Wright, A. K., Romeo, S., Gouni-Berthold, I., Maan, A., Durrington, P. N., et al. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1389106 · Cited by 40 · see citing works
Okamura, T., Kokubo, Y., Watanabe, M., Higashiyama, A., Ono, Y., Miyamoto, Y., Yoshimasa, Y., & Okayama, A. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.09.012 · Cited by 35 · see citing works
Postprandial lipaemia and vascular disease
Kolovou, G., & Ooi, T. C. (2013) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3283606971 · Cited by 32 · see citing works
for the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group, Hirata, T., Sugiyama, D., Nagasawa, S.-Y., Murakami, Y., Saitoh, S., Okayama, A., Iso, H., Irie, F., Sairenchi, T., et al. (2017) · European Journal of Epidemiology · doi:10.1007/s10654-016-0203-1 · Cited by 23 · see citing works
Kakehi, E., Kotani, K., Ishikawa, S., Gotoh, T., Kayaba, K., Nakamura, Y., & Kajii, E. (2015) · Asia Pacific Journal of Public Health · doi:10.1177/1010539513475649 · Cited by 12 · see citing works
- Authors
- Asia Pacific Cohort Studies Collaboration
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Asia Pacific Cohort Studies Collaboration
- Venue
- Circulation
- Published
- 2004-10-26
- Volume
- 110
- Issue
- 17
- Pages
- 2678-2686
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2117541022
- Cited by
- 358
- References
- 51
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 13 · 2023: 20 · 2022: 13 · 2021: 15 · 2020: 13 · 2019: 17 · 2018: 15 · 2017: 12 · 2016: 22 · 2015: 19 · 2014: 21 · 2013: 21 · 2012: 24
- FWCI
- 9.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- Funders
- Pfizer
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council
- Health Research Council of New Zealand
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Keywords
- serum triglycerides, cardiovascular risk, coronary artery disease, stroke, cardiovascular mortality, lipid-lowering therapy, cardiovascular risk prediction, Asia-Pacific population
- MeSH terms
- Aged, Asia, Australia, Coronary Disease, Female, Humans, Male, Middle Aged, New Zealand, Risk Factors, Triglycerides, Stroke
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