Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Jauch, Edward C.; Saver, Jeffrey L.; Adams, Harold P.; Bruno, Askiel; Connors, J.J. (Buddy); Demaerschalk, Bart M.; Khatri, Pooja; McMullan, Paul W.; Qureshi, Adnan I.; Rosenfield, Kenneth; Scott, Phillip A.; Summers, Debbie R.; Wang, David Z.; Wintermark, Max; Yonas, Howard

doi:10.1161/str.0b013e318284056a

Cited by 7,634

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Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

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Jauch, Edward C., Saver, Jeffrey L., Adams, Harold P., Bruno, Askiel, Connors, J.J. (Buddy), Demaerschalk, Bart M., Khatri, Pooja, McMullan, Paul W., Qureshi, Adnan I., Rosenfield, Kenneth, Scott, Phillip A., Summers, Debbie R., Wang, David Z., Wintermark, Max, Yonas, Howard·2013·Stroke

DOI 10.1161/str.0b013e318284056a

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Abstract

Background and Purpose—: The authors present an overview of the current evidence and management recommendations for evaluation and treatment of adults with acute ischemic stroke. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators responsible for the care of acute ischemic stroke patients within the first 48 hours from stroke onset. These guidelines supersede the prior 2007 guidelines and 2009 updates. Methods—: Members of the writing committee were appointed by the American Stroke Association Stroke Council’s Scientific Statement Oversight Committee, representing various areas of medical expertise. Strict adherence to the American Heart Association conflict of interest policy was maintained throughout the consensus process. Panel members were assigned topics relevant to their areas of expertise, reviewed the stroke literature with emphasis on publications since the prior guidelines, and drafted recommendations in accordance with the American Heart Association Stroke Council’s Level of Evidence grading algorithm. Results—: The goal of these guidelines is to limit the morbidity and mortality associated with stroke. The guidelines support the overarching concept of stroke systems of care and detail aspects of stroke care from patient recognition; emergency medical services activation, transport, and triage; through the initial hours in the emergency department and stroke unit. The guideline discusses early stroke evaluation and general medical care, as well as ischemic stroke, specific interventions such as reperfusion strategies, and general physiological optimization for cerebral resuscitation. Conclusions—: Because many of the recommendations are based on limited data, additional research on treatment of acute ischemic stroke remains urgently needed.

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Authors: Jauch, E. C., Saver, J. L., Adams, H. P., Bruno, A., Connors, J. J. (., Demaerschalk, B. M., Khatri, P., McMullan, P. W., Qureshi, A. I., Rosenfield, K., Scott, P. A., Summers, D. R., Wang, D. Z., Wintermark, M., & Yonas, H.
Venue: Stroke
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2013-03
Volume: 44
Issue: 3
Pages: 870-947
ISSN: 0039-2499 (ISSN-L)
1524-4628
DOI: 10.1161/str.0b013e318284056a
OpenAlex: W2171165037
Cited by: 7,634
References: 27
FWCI: 402.56
Type: journal article
Language: en
Open access: bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page: CoChat. (2026). Citation check: Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. https://app.cochat.ai/papers/10.1161/str.0b013e318284056a
The paper: Jauch, E. C., Saver, J. L., Adams, H. P., Bruno, A., Connors, J. J. (., Demaerschalk, B. M., Khatri, P., McMullan, P. W., Qureshi, A. I., Rosenfield, K., Scott, P. A., Summers, D. R., Wang, D. Z., Wintermark, M., & Yonas, H. (2013). Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. https://doi.org/10.1161/str.0b013e318284056a

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

How to cite

Data sources