Translating Across Circuits and Genetics Toward Progress in Fear- and Anxiety-Related Disorders

Memory - A century of consolidation

McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250 · see citing works

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

da Luz, A. C. D. D. S., Dias, G. P., Bevilaqua, M. C. D. N., Cocks, G. D., Gardino, P. F., Thuret, S., & Nardi, A. E. (2013) · Neuropsychobiology · doi:10.1159/000353269 · Cited by 4,012 · see citing works

Maximizing exposure therapy: An inhibitory learning approach

Craske, M. G., Treanor, M., Conway, C. C., Zbozinek, T., & Vervliet, B. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.04.006 · Cited by 2,339 · cited 1× · see citing works

From circuits to behaviour in the amygdala

Janak, P. H., & Tye, K. M. (2015) · Nature · doi:10.1038/nature14188 · Cited by 2,011 · see citing works

Context and Behavioral Processes in Extinction: Table 1.

Bouton, M. E. (2004) · Learning & Memory · doi:10.1101/lm.78804 · Cited by 1,808 · see citing works

Effects of an expanding-spaced vs massed exposure schedule on fear reduction and return of fear

Rowe, M. K., & Craske, M. G. (1998) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(97)10016-x · Cited by 1,778 · see citing works

The Neurobiology of Consolidations, Or, How Stable is the Engram?

Dudai, Y. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.142050 · Cited by 1,671 · see citing works

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

Milad, M. R., Pitman, R. K., Ellis, C. B., Gold, A. L., Shin, L. M., Lasko, N. B., Zeidan, M. A., Handwerger, K., Orr, S. P., & Rauch, S. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.026 · Cited by 1,339 · see citing works

Mechanisms of fear extinction

Myers, K. M., & Davis, M. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001939 · Cited by 1,277 · see citing works

Cognitive Enhancers as Adjuncts to Psychotherapy: Use of D-Cycloserine in Phobic Individuals to Facilitate Extinctionof Fear

Ressler, K. J., Rothbaum, B. O., Tannenbaum, L., Anderson, P., Graap, K., Zimand, E., Hodges, L., & Davis, M. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.11.1136 · Cited by 1,063 · see citing works

Molecular mechanisms of fear learning and memory

Johansen, J. P., Cain, C. K., Ostroff, L. E., & LeDoux, J. E. (2011) · Cell · doi:10.1016/j.cell.2011.10.009 · Cited by 1,012 · see citing works

Encoding of conditioned fear in central amygdala inhibitory circuits

Ciocchi, S., Herry, C., Grenier, F., Wolff, S. B. E., Letzkus, J. J., Vlachos, I., Ehrlich, I., Sprengel, R., Deisseroth, K., Stadler, M. B., et al. (2010) · Nature · doi:10.1038/nature09559 · Cited by 924 · see citing works

Behavioral and Neural Analysis of Extinction

Myers, K. M., & Davis, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)01064-4 · Cited by 918 · see citing works

Genetic dissection of an amygdala microcircuit that gates conditioned fear

Haubensak, W., Kunwar, P. S., Cai, H., Ciocchi, S., Wall, N. R., Ponnusamy, R., Biag, J., Dong, H.-W., Deisseroth, K., Callaway, E. M., et al. (2010) · Nature · doi:10.1038/nature09553 · Cited by 840 · see citing works

Beyond extinction: erasing human fear responses and preventing the return of fear

Kindt, M., Soeter, M., & Vervliet, B. (2009) · Nature Neuroscience · doi:10.1038/nn.2271 · Cited by 826 · see citing works

Facilitation of Conditioned Fear Extinction by Systemic Administration or Intra-Amygdala Infusions of d-Cycloserine as Assessed with Fear-Potentiated Startle in Rats

Walker, D. L., Ressler, K. J., Lu, K.-T., & Davis, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-06-02343.2002 · Cited by 815 · see citing works

Contextual control of the extinction of conditioned fear: Tests for the associative value of the context.

Bouton, M. E., & King, D. A. (1983) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.9.3.248 · Cited by 771 · see citing works

Reinstatement of fear to an extinguished conditioned stimulus.

Rescorla, R. A., & Heth, C. D. (1975) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.1.1.88 · Cited by 768 · see citing works

Neural circuitry underlying the regulation of conditioned fear and its relation to extinction

Delgado, M. R., Nearing, K. I., LeDoux, J. E., & Phelps, E. A. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.029 · Cited by 716 · see citing works

Finding the engram

Josselyn, S. A., Köhler, S., & Frankland, P. W. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn4000 · Cited by 687 · see citing works

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

Heldt, S. A., Stanek, L., Chhatwal, J. P., & Ressler, K. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001957 · Cited by 684 · see citing works

Psychiatric Genomics: An Update and an Agenda

Sullivan, P. F., Agrawal, A., Bulik, C. M., Andreassen, O. A., Børglum, A. D., Breen, G., Cichon, S., Edenberg, H. J., Faraone, S. V., Gelernter, J., et al. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17030283 · Cited by 676 · see citing works

Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala

Falls, W., Miserendino, M., & Davis, M. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-03-00854.1992 · Cited by 673 · see citing works

Brain activation in PTSD in response to trauma-related stimuli

Liberzon, I., Taylor, S. F., Amdur, R., Jung, T. D., Chamberlain, K. R., Minoshima, S., Koeppe, R. A., & Fig, L. M. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00246-7 · Cited by 635 · see citing works

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12576-w · Cited by 635 · see citing works

Fear extinction in rats: Implications for human brain imaging and anxiety disorders

Milad, M. R., Rauch, S. L., Pitman, R. K., & Quirk, G. J. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.01.008 · Cited by 597 · see citing works

Augmentation of Exposure Therapy With D-Cycloserine for Social Anxiety Disorder

Hofmann, S. G., Meuret, A. E., Smits, J. A. J., Simon, N. M., Pollack, M. H., Eisenmenger, K., Shiekh, M., & Otto, M. W. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.3.298 · Cited by 560 · see citing works

Untitled work

(1996) · PubMed · Cited by 547 · see citing works

Experience-dependent modification of a central amygdala fear circuit

Li, H., Penzo, M. A., Taniguchi, H., Kopec, C. D., Huang, Z. J., & Li, B. (2013) · Nature Neuroscience · doi:10.1038/nn.3322 · Cited by 497 · see citing works

Role of conditioned contextual stimuli in reinstatement of extinguished fear.

Bouton, M. E., & Bolles, R. C. (1979) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037//0097-7403.5.4.368 · Cited by 481 · see citing works

Reconsolidation and Extinction of Conditioned Fear: Inhibition and Potentiation

Lee, J. L. C., Milton, A. L., & Everitt, B. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.2466-06.2006 · Cited by 479 · see citing works

Implications of memory modulation for post-traumatic stress and fear disorders

Parsons, R. G., & Ressler, K. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3296 · Cited by 476 · see citing works

A competitive inhibitory circuit for selection of active and passive fear responses

Fadok, J. P., Krabbe, S., Marković, M., Courtin, J., Xu, C., Massi, L., Botta, P., Bylund, K., Müller, C. R., Kovacevic, A., et al. (2017) · Nature · doi:10.1038/nature21047 · Cited by 475 · see citing works

Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

Fenster, R. J., Lebois, L. A. M., Ressler, K. J., & Suh, J. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0039-7 · Cited by 456 · see citing works

Applying Learning Principles to the Treatment of Post‐Trauma Reactions

ROTHBAUM, B. O., & DAVIS, M. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1301.012 · Cited by 454 · see citing works

The PsychENCODE project

Akbarian, S., Liu, C., Knowles, J. A., Vaccarino, F. M., Farnham, P. J., Crawford, G. E., Jaffe, A. E., Pinto, D., Dracheva, S., Geschwind, D. H., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4156 · Cited by 451 · see citing works

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

Duncan, L. E., Ratanatharathorn, A., Aiello, A. E., Almli, L. M., Amstadter, A. B., Ashley-Koch, A. E., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J., et al. (2018) · Molecular Psychiatry · doi:10.1038/mp.2017.77 · Cited by 425 · see citing works

Divergent routing of positive and negative information from the amygdala during memory retrieval

Beyeler, A., Namburi, P., Glober, G. F., Simonnet, C., Calhoon, G. G., Conyers, G. F., Luck, R., Wildes, C. P., & Tye, K. M. (2016) · Neuron · doi:10.1016/j.neuron.2016.03.004 · Cited by 412 · see citing works

Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2

Radulovic, J., Rühmann, A., Liepold, T., & Spiess, J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05016.1999 · Cited by 402 · see citing works

Fear Extinction in Traumatized Civilians with Posttraumatic Stress Disorder: Relation to Symptom Severity

Norrholm, S. D., Jovanovic, T., Olin, I. W., Sands, L. A., Karapanou, I., Bradley, B., & Ressler, K. J. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.013 · Cited by 397 · see citing works

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

Singewald, N., Schmuckermair, C., Whittle, N., Holmes, A., & Ressler, K. J. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.12.004 · Cited by 390 · cited 2× · see citing works

Effects of D-cycloserine on extinction of conditioned freezing.

Ledgerwood, L., Richardson, R., & Cranney, J. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.2.341 · Cited by 388 · see citing works

The Study of Fear Extinction: Implications for Anxiety Disorders

Graham, B. M., & Milad, M. R. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11040557 · Cited by 387 · see citing works

D-Cycloserine Augmented Exposure Therapy for Obsessive-Compulsive Disorder

Kushner, M. G., Kim, S. W., Donahue, C. B., THURAS, P. D., Adson, D. E., Kotlyar, M., McCabe, J., Peterson, J., & Foa, E. B. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.020 · Cited by 384 · see citing works

Role of conditioned contextual stimuli in reinstatement of extinguished fear.

Bouton, M. E., & Bolles, R. C. (1979) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.5.4.368 · Cited by 376 · see citing works

The efficacy of exposure therapy for anxiety-related disorders and its underlying mechanisms: The case of OCD and PTSD

Foa, E. B., & McLean, C. P. (2016) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-021815-093533 · Cited by 360 · see citing works

Augmentation of Behavior Therapy With <scp>d</scp> -Cycloserine for Obsessive-Compulsive Disorder

Wilhelm, S., Buhlmann, U., Tolin, D. F., Meunier, S. A., Pearlson, G. D., Reese, H. E., Cannistraro, P., Jenike, M. A., & Rauch, S. L. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07050776 · Cited by 358 · see citing works

Estradiol Modulates Medial Prefrontal Cortex and Amygdala Activity During Fear Extinction in Women and Female Rats

Zeidan, M. A., Igoe, S. A., Linnman, C., Vitalo, A., Levine, J. B., Klibanski, A., Goldstein, J. M., & Milad, M. R. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.05.016 · Cited by 354 · see citing works

A Randomized Controlled Trial of D-Cycloserine Enhancement of Exposure Therapy for Social Anxiety Disorder

Guastella, A. J., Richardson, R., Lovibond, P. F., Rapee, R. M., Gaston, J. E., Mitchell, P., & Dadds, M. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.11.011 · Cited by 326 · see citing works

Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment

Burgos-Robles, A., Kimchi, E. Y., Izadmehr, E. M., Porzenheim, M. J., Ramos-Guasp, W. A., Nieh, E. H., Felix-Ortiz, A. C., Namburi, P., Leppla, C. A., Presbrey, K. N., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4553 · Cited by 318 · see citing works

Mice Deficient for Both Corticotropin-Releasing Factor Receptor 1 (CRFR1) and CRFR2 Have an Impaired Stress Response and Display Sexually Dichotomous Anxiety-Like Behavior

Bale, T. L., Picetti, R., Contarino, A., Koob, G. F., Vale, W., & Lee, K. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00193.2002 · Cited by 293 · see citing works

Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder

Stevens, J. S., Jovanovic, T., Fani, N., Ely, T. D., Glover, E. M., Bradley, B., & Ressler, K. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.05.031 · Cited by 293 · see citing works

D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data

Mataix-Cols, D., Fernández de la Cruz, L., Monzani, B., Rosenfield, D., Andersson, E., Pérez-Vigil, A., Frumento, P., de Kleine, R. A., Difede, J., Dunlop, B. W., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3955 · Cited by 288 · see citing works

Fear extinction and BDNF: translating animal models of PTSD to the clinic

Andero, R., & Ressler, K. J. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00801.x · Cited by 275 · see citing works

Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program

Levey, D. F., Gelernter, J. E., Polimanti, R. A., Zhou, H., Cheng, Z., Aslan, M., Quaden, R. M., Concato, J., Radhakrishnan, K., Bryois, J., et al. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19030256 · Cited by 275 · see citing works

Estrogen Levels Are Associated with Extinction Deficits in Women with Posttraumatic Stress Disorder

Glover, E. M., Jovanović, T., Mercer, K. B., Kerley, K. A., Bradley, B., Ressler, K. J., & Norrholm, S. D. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.02.031 · Cited by 259 · see citing works

A 6-Week Randomized, Placebo-Controlled Trial of CP-316,311 (a Selective CRH ₁ Antagonist) in the Treatment of Major Depression

Binneman, B., Feltner, D., Kolluri, S., Shi, Y., Qiu, R., & Stiger, T. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07071199 · Cited by 254 · see citing works

Amygdala BDNF signaling is required for consolidation but not encoding of extinction

Chhatwal, J. P., Rattiner, L. M., Davis, M., & Ressler, K. J. (2006) · Nature Neuroscience · doi:10.1038/nn1718 · Cited by 243 · see citing works

Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

Sartori, S. B., & Singewald, N. (2019) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2019.107402 · Cited by 236 · see citing works

D-cycloserine facilitates extinction of learned fear: effects on reacquisition and generalized extinction.

Ledgerwood, L., Richardson, R., & Cranney, J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.01.023 · Cited by 234 · see citing works

Effect of 7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, on Emotional Learning

Andero, R., Heldt, S. A., Ye, K., Liu, X., Armario, A., & Ressler, K. J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10030326 · Cited by 224 · see citing works

Regulation of Synaptic Plasticity Genes during Consolidation of Fear Conditioning

Ressler, K. J., Paschall, G. Y., Zhou, X., & Davis, M. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-18-07892.2002 · Cited by 217 · see citing works

Dopamine and extinction: A convergence of theory with fear and reward circuitry

Abraham, A. D., Neve, K., & Lattal, K. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.11.007 · Cited by 211 · see citing works

Fear conditioning in panic disorder: Enhanced resistance to extinction

Michael, T., Blechert, J., Vriends, N., Margraf, J., & Wilhelm, F. H. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.3.612 · Cited by 210 · see citing works

A neural switch for active and passive fear

Gozzi, A., Jain, A., Giovanelli, A., Bertollini, C., Crestan, V., Schwarz, A. J., Tsetsenis, T., Ragozzino, D., Gross, C. T., & Bifone, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.07.008 · Cited by 209 · see citing works

Memory processes in classical conditioning.

Bouton, M., & Moody, E. W. (2004) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.001 · Cited by 208 · see citing works

Viewpoints: Approaches to defining and investigating fear

Mobbs, D., Adolphs, R., Fanselow, M. S., Barrett, L. F., LeDoux, J. E., Ressler, K., & Tye, K. M. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0456-6 · Cited by 202 · see citing works

Active Avoidance Requires a Serial Basal Amygdala to Nucleus Accumbens Shell Circuit

Ramirez, F., Moscarello, J. M., LeDoux, J. E., & Sears, R. M. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.1331-14.2015 · Cited by 198 · see citing works

Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans

Gelernter, J. E., Sun, N., Polimanti, R. A., Pietrzak, R. H., Levey, D. F., Bryois, J., Lu, Q., Hu, Y., Li, B., Radhakrishnan, K., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0447-7 · Cited by 198 · see citing works

D-Cycloserine and the Facilitation of Extinction of Conditioned Fear: Consequences for Reinstatement.

Ledgerwood, L., Richardson, R., & Cranney, J. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.3.505 · Cited by 190 · see citing works

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

Stein, M. B., Chen, C., Ursano, R. J., Cai, T., Gelernter, J. E., Heeringa, S. G., Jain, S., Jensen, K. P., Maihofer, A. X., Mitchell, C. M., et al. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.0350 · Cited by 182 · see citing works

Maximizing exposure therapy An inhibitory learning approach

Pittig, A., Stevens, S., Vervliet, B., Treanor, M., Conway, C., Zbozinek, T. D., & Craske, M. G. (2015) · Kölner Universitäts PublikationsServer (Universität zu Köln) · Cited by 182 · see citing works

Neuronal Allocation to a Hippocampal Engram

Park, S., Kramer, E. E., Mercaldo, V., Rashid, A. J., Insel, N., Frankland, P. W., & Josselyn, S. A. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.73 · Cited by 179 · see citing works

Amygdala Reactivity and Anterior Cingulate Habituation Predict Posttraumatic Stress Disorder Symptom Maintenance After Acute Civilian Trauma

Stevens, J. S., Kim, Y. J., Galatzer-Levy, I. R., Reddy, R., Ely, T. D., Nemeroff, C. B., Hudak, L. A., Jovanovic, T., Rothbaum, B. O., & Ressler, K. J. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.11.015 · Cited by 177 · see citing works

The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure

McLean, S. A., Ressler, K. J., Koenen, K. C., Neylan, T. C., Germine, L. T., Jovanović, T., Clifford, G. D., Zeng, D., An, X., Linnstaedt, S. D., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0581-3 · Cited by 177 · see citing works

Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder

Coric, V., Feldman, H., Oren, D. A., Shekhar, A., Pultz, J. A., Dockens, R. C., Wu, X., Gentile, K. A., Huang, S.-P., Emison, E., et al. (2010) · Depression and Anxiety · doi:10.1002/da.20695 · Cited by 172 · see citing works

An Integrated Neuroscience Perspective on Formulation and Treatment Planning for Posttraumatic Stress Disorder

Ross, D. A., Arbuckle, M. R., Travis, M. J., Dwyer, J. B., van Schalkwyk, G. I., & Ressler, K. J. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3325 · Cited by 165 · see citing works

Perineuronal Nets in the Adult Sensory Cortex Are Necessary for Fear Learning

Banerjee, S. B., Gutzeit, V. A., Baman, J., Aoued, H. S., Doshi, N. K., Liu, R. C., & Ressler, K. J. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.007 · Cited by 163 · see citing works

The Role of CRF in Behavioral Aspects of Stress

Heinrichs, S. C., Menzaghi, F., Pich, E. M., Britton, K. T., & Koob, G. F. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44673.x · Cited by 160 · see citing works

Efficacy of Deep Brain Stimulation of the Ventral Anterior Limb of the Internal Capsule for Refractory Obsessive-Compulsive Disorder: A Clinical Cohort of 70 Patients

Denys, D. A. J. P., Graat, I., Mocking, R. J. T., de Koning, P. P., Vulink, N. C. C., Figee, M., Ooms, P., Mantione, M. H. M., van den Munckhof, P., & Schuurman, R. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19060656 · Cited by 159 · see citing works

Deconstructing the Gestalt: Mechanisms of Fear, Threat, and Trauma Memory Encoding

Maddox, S. A., Hartmann, J., Ross, R., & Ressler, K. J. (2019) · Neuron · doi:10.1016/j.neuron.2019.03.017 · Cited by 150 · see citing works

An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials

Bowers, M. E., & Ressler, K. J. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.06.008 · Cited by 147 · see citing works

Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample

Jovanovic, T., Ely, T., Fani, N., Glover, E. M., Gutman, D., Tone, E. B., Norrholm, S. D., Bradley, B., & Ressler, K. J. (2013) · Cortex · doi:10.1016/j.cortex.2012.08.011 · Cited by 146 · see citing works

Chronic overexpression of corticotropin-releasing factor from the central amygdala produces HPA axis hyperactivity and behavioral anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus

Flandreau, E. I., Ressler, K. J., Owens, M. J., & Nemeroff, C. B. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.04.014 · Cited by 143 · see citing works

Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety

Dedic, N., Kühne, C., Jakovcevski, M., Hartmann, J., Genewsky, A. J., Gomes, K. S., Anderzhanova, E. A., Pöhlmann, M. L., Chang, S., Kolarz, A., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0151-z · Cited by 139 · see citing works

Functional Connectivity within the Primate Extended Amygdala Is Heritable and Associated with Early-Life Anxious Temperament

Fox, A. S., Oler, J. A., Birn, R. M., Shackman, A. J., Alexander, A. L., & Kalin, N. H. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0102-18.2018 · Cited by 135 · see citing works

Voxel-based morphometry predicts shifts in dendritic spine density and morphology with auditory fear conditioning

Keifer Jr, O. P., Hurt, R. C., Gutman, D. A., Keilholz, S. D., Gourley, S. L., & Ressler, K. J. (2015) · Nature Communications · doi:10.1038/ncomms8582 · Cited by 132 · see citing works

Neural Substrates of Treatment Response to Cognitive-Behavioral Therapy in Panic Disorder With Agoraphobia

Lueken, U., Straube, B., Konrad, C., Wïttchen, H., Ströhle, A., Wittmann, A., Pfleiderer, B., Uhlmann, C., Arolt, V., Jansen, A., et al. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12111484 · Cited by 129 · see citing works

Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes

Keen‐Rhinehart, E., Michopoulos, V., Toufexis, D. J., Martin, E. I., Nair, H. P., Ressler, K. J., Davis, M., Owens, M. J., Nemeroff, C. B., & Wilson, M. E. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.91 · Cited by 126 · see citing works

Emotion Regulation and Trait Anxiety Are Predicted by the Microstructure of Fibers between Amygdala and Prefrontal Cortex

Eden, A. S., Schreiber, J., Anwander, A., Keuper, K., Laeger, I., Zwanzger, P., Zwitserlood, P., Kugel, H., & Dobel, C. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3659-14.2015 · Cited by 123 · see citing works

Neuronal Circuits for Fear Expression and Recovery: Recent Advances and Potential Therapeutic Strategies

Déjean, C., Courtin, J., Rozeske, R. R., Bonnet, M. C., Dousset, V., Michelet, T., & Herry, C. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.03.017 · Cited by 120 · see citing works

Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions

Norrholm, S. D., Glover, E. M., Stevens, J. S., Fani, N., Galatzer‐Levy, I. R., Bradley, B., Ressler, K. J., & Jovanović, T. (2014) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2014.11.005 · Cited by 115 · see citing works

GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN

Dunn, E. C., Wiste, A. K., Radmanesh, F., Almli, L. M., Gogarten, S. M., Sofer, T., Faul, J. D., Kardia, S. L. R., Smith, J. A., Weir, D. R., et al. (2016) · Depression and Anxiety · doi:10.1002/da.22484 · Cited by 114 · see citing works

Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety

Sink, K. S., Walker, D. L., Freeman, S. M., Flandreau, E. I., Ressler, K. J., & Davis, M. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.188 · Cited by 108 · see citing works

Phasic Dopamine Signals in the Nucleus Accumbens that Cause Active Avoidance Require Endocannabinoid Mobilization in the Midbrain

Wenzel, J. M., Oleson, E. B., Gove, W. N., Cole, A. B., Gyawali, U., Dantrassy, H. M., Bluett, R. J., Dryanovski, D. I., Stuber, G. D., Deisseroth, K. A., et al. (2018) · Current Biology · doi:10.1016/j.cub.2018.03.037 · Cited by 103 · see citing works

Rodent models of impaired fear extinction

Singewald, N., & Holmes, A. (2018) · Psychopharmacology · doi:10.1007/s00213-018-5054-x · Cited by 98 · see citing works

Cell-type specific deletion of GABA(A)α1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction

Gafford, G. M., Guo, J., Flandreau, E. I., Hazra, R., Rainnie, D. G., & Ressler, K. J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119261109 · Cited by 96 · see citing works

Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy

Norrholm, S. D., Jovanović, T., Gerardi, M. A., Breazeale, K. G., Price, M., Davis, M., Duncan, E., Ressler, K. J., Bradley, B., Rizzo, A., et al. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.05.002 · Cited by 96 · see citing works

Corticotropin-releasing factor receptor 1 antagonism is ineffective for women with posttraumatic stress disorder

Dunlop, B. W., Binder, E. B., Iosifescu, D., Mathew, S. J., Neylan, T. C., Pape, J. C., Carrillo-Roa, T., Green, C., Kinkead, B., Grigoriadis, D., et al. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.06.024 · Cited by 96 · see citing works

Brain activation during fear extinction predicts exposure success

Ball, T. M., Knapp, S. E., Paulus, M. P., & Stein, M. B. (2016) · Depression and Anxiety · doi:10.1002/da.22583 · Cited by 94 · see citing works

Inhibition of fear is differentially associated with cycling estrogen levels in women

Glover, E. M., Mercer, K. B., Norrholm, S. D., Davis, M., Duncan, E., Bradley, B., Ressler, K. J., & Jovanović, T. (2013) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.120129 · Cited by 93 · see citing works

Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci

Gelernter, J. E., Sun, N., Polimanti, R. A., Pietrzak, R. H., Levey, D. F., Lu, Q., Hu, Y., Li, B., Radhakrishnan, K., Aslan, M., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.03.984 · Cited by 83 · see citing works

Amygdala-ventral striatum circuit activation decreases long-term fear

Correia, S. S., McGrath, A. G., Lee, A., Graybiel, A. M., & Goosens, K. A. (2016) · eLife · doi:10.7554/elife.12669 · Cited by 82 · see citing works

Fear extinction reverses dendritic spine formation induced by fear conditioning in the mouse auditory cortex

Lai, C. S. W., Adler, A., & Gan, W. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1801504115 · Cited by 82 · see citing works

Inhibition of estradiol synthesis impairs fear extinction in male ratsPreprint

Graham, B. M., & Milad, M. R. (2014) · Learning & Memory · doi:10.1101/lm.034926.114 · Cited by 81 · see citing works

Overexpressing Corticotropin-Releasing Factor in the Primate Amygdala Increases Anxious Temperament and Alters Its Neural Circuit

Kalin, N. H., Fox, A. S., Kovner, R., Riedel, M. K., Fekete, E. M., Roseboom, P. H., Tromp, D., Grabow, B. P., Olsen, M. E., Brodsky, E. K., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.01.010 · Cited by 77 · see citing works

An Electroencephalography Connectomic Profile of Posttraumatic Stress Disorder

Toll, R. T., Wu, W., Naparstek, S., Zhang, Y., Narayan, M., Patenaude, B., Angeles, C. D. L., Sarhadi, K. J., Anicetti, N., Longwell, P., et al. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.18080911 · Cited by 74 · see citing works

Measuring fear change within exposures: Functionally-defined habituation predicts outcome in three randomized controlled trials for pediatric OCD

Benito, K. G., Machan, J., Freeman, J. B., Garcia, A. M., Walther, M., Frank, H., Wellen, B., Stewart, E., Edmunds, J., Kemp, J., et al. (2018) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000315 · Cited by 73 · see citing works

The roles of the nucleus accumbens core, dorsomedial striatum, and dorsolateral striatum in learning: Performance and extinction of Pavlovian fear-conditioned responses and instrumental avoidance responses

Wendler, E., Gaspar, J. C. C., Ferreira, T. L., Barbiero, J. K., Andreatini, R., Vital, M. A. B. F., Blaha, C. D., Winn, P., & Da Cunha, C. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.11.009 · Cited by 65 · see citing works

Central amygdala nucleus (Ce) gene expression linked to increased trait-like Ce metabolism and anxious temperament in young primates

Fox, A. S., Oler, J. A., Shelton, S. E., Nanda, S. A., Davidson, R. J., Roseboom, P. H., & Kalin, N. H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206723109 · Cited by 57 · see citing works

Dexamethasone facilitates fear extinction and safety discrimination in PTSD: A placebo-controlled, double-blind study

Michopoulos, V., Norrholm, S. D., Stevens, J. S., Glover, E. M., Rothbaum, B. O., Gillespie, C. F., Schwartz, A. C., Ressler, K. J., & Jovanović, T. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.05.023 · Cited by 57 · see citing works

Individual Patterns of Abnormality in Resting-State Functional Connectivity Reveal Two Data-Driven PTSD Subgroups

Maron‐Katz, A., Zhang, Y., Narayan, M., Wu, W., Toll, R. T., Naparstek, S., Angeles, C. D. L., Longwell, P., Shpigel, E., Newman, J., et al. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19010060 · Cited by 56 · see citing works

A cross species study of heterogeneity in fear extinction learning in relation to FKBP5 variation and expression: Implications for the acute treatment of posttraumatic stress disorder

Galatzer‐Levy, I. R., Andero, R., Sawamura, T., Jovanović, T., Papini, S., Ressler, K. J., & Norrholm, S. D. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.12.023 · Cited by 53 · see citing works

175 Years of Progress in PTSD Therapeutics: Learning From the Past

Stein, M. B., & ROTHBAUM, B. O. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17080955 · Cited by 53 · see citing works

Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis

Rosenfield, D., Smits, J. A. J., Hofmann, S. G., Mataix‐Cols, D., de la Cruz, L. F., Andersson, E., Rück, C., Monzani, B. A., Pérez-Vigil, A., Frumento, P., et al. (2019) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2019.102149 · Cited by 52 · see citing works

Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala

McCullough, K. M., Choi, D., Guo, J., Zimmerman, K., Walton, J., Rainnie, D. G., & Ressler, K. J. (2016) · Nature Communications · doi:10.1038/ncomms13149 · Cited by 51 · see citing works

Association between posttraumatic stress disorder severity and amygdala habituation to fearful stimuli

Kim, Y. J., van Rooij, S. J. H., Ely, T. D., Fani, N., Ressler, K. J., Jovanović, T., & Stevens, J. S. (2019) · Depression and Anxiety · doi:10.1002/da.22928 · Cited by 49 · see citing works

Positive affect predicts less reacquisition of fear: relevance for long-term outcomes of exposure therapy

Zbozinek, T. D., & Craske, M. G. (2016) · Cognition & Emotion · doi:10.1080/02699931.2016.1142428 · Cited by 46 · see citing works

Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial

Dunlop, B. W., Rothbaum, B. O., Binder, E. B., Duncan, E., Harvey, P. D., Jovanovic, T., Kelley, M. E., Kinkead, B., Kutner, M., Iosifescu, D. V., et al. (2014) · Trials · doi:10.1186/1745-6215-15-240 · Cited by 45 · see citing works

Bridging the Gap : Towards a cell-type specific understanding of neural circuits underlying fear behaviors

McCullough, K. M., Morrison, F. G., & Ressler, K. J. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.07.025 · Cited by 45 · see citing works

Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity

Dedic, N., Kühne, C., Gomes, K. S., Hartmann, J., Ressler, K. J., Schmidt, M. V., & Deussing, J. M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00986 · Cited by 44 · see citing works

From Candidate Genes to Genome-wide Association: The Challenges and Promise of Posttraumatic Stress Disorder Genetic Studies

Koenen, K. C., Duncan, L. E., Liberzon, I., & Ressler, K. J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.08.022 · Cited by 43 · see citing works

Hippocampal cytosolic estrogen receptors regulate fear generalization in females

Lynch, J. F., Winiecki, P., Vanderhoof, T. S., Riccio, D. C., & Jasnow, A. M. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.01.010 · Cited by 43 · see citing works

Psychiatric Genomics: An Update and an AgendaPreprint

Sullivan, P. F., Agrawal, A., Bulik, C. M., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/115600 · Cited by 39 · see citing works

Psychophysiological treatment outcomes: Corticotropin‐releasing factor type 1 receptor antagonist increases inhibition of fear‐potentiated startle in PTSD patients

Jovanović, T., Duncan, E., Kaye, J. L., Garza, K. M., Norrholm, S. D., Inslicht, S. S., Neylan, T. C., Mathew, S. J., Iosifescu, D. V., ROTHBAUM, B. O., et al. (2019) · Psychophysiology · doi:10.1111/psyp.13356 · Cited by 33 · see citing works

Grin1 Receptor Deletion within CRF Neurons Enhances Fear Memory

Gafford, G. M., Jasnow, A. M., & Ressler, K. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111009 · Cited by 32 · see citing works

The Research Domain Criteria (RDoC) and the historical roots of psychopathology: A viewpoint

Stoyanov, D., Telles‐Correia, D., & Cuthbert, B. N. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2018.11.007 · Cited by 29 · see citing works

Effect of CBT on Biased Semantic Network in Panic Disorder: A Multicenter fMRI Study Using Semantic Priming

Yang, Y., Lueken, U., Richter, J., Hamm, A. O., Wittmann, A., Konrad, C., Ströhle, A., Pfleiderer, B., Herrmann, M. J., Lang�, T., et al. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19020202 · Cited by 28 · see citing works

Fear-Potentiated Startle and Fear Extinction in a Sample of Undergraduate Women Exposed to a Campus Mass Shooting

Orcutt, H. K., Hannan, S. M., Seligowski, A. V., Jovanović, T., Norrholm, S. D., Ressler, K. J., & McCanne, T. R. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.02031 · Cited by 18 · see citing works

Extreme early-life anxiety is associated with an evolutionarily conserved reduction in the strength of intrinsic functional connectivity between the dorsolateral prefrontal cortex and the central nucleus of the amygdala

Birn, R. M., Shackman, A. J., Oler, J. A., Williams, L. E., McFarlin, D. R., Rogers, G. M., Shelton, S. E., Alexander, A. L., Pine, D. S., Slattery, M. J., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.85 · Cited by 17 · see citing works

Extending the Examination of the Fear Extinction Network Beyond Anxiety and Fear-Based Disorders: Insight Into Autism Spectrum Disorder

Marin, M., & Milad, M. R. (2016) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2016.05.002 · Cited by 6 · see citing works

Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

Ressler, K. J., Berretta, S., Bolshakov, V. Y., Rosso, I. M., Meloni, E. G., Rauch, S. L., & Carlezon, W. A. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00635-8 · Cited by 531 · see citing works

Psychiatric diagnosis and treatment in the 21st century: paradigm shifts versus incremental integration

Stein, D. J., Shoptaw, S. J., Vigo, D. V., Lund, C., Cuijpers, P., Bantjes, J., Sartorius, N., & Maj, M. (2022) · World Psychiatry · doi:10.1002/wps.20998 · Cited by 331 · see citing works

Putting the “mental” back in “mental disorders”: a perspective from research on fear and anxiety

Taschereau‐Dumouchel, V., Michel, M., Lau, H. C., Hofmann, S. G., & LeDoux, J. E. (2022) · Molecular Psychiatry · doi:10.1038/s41380-021-01395-5 · Cited by 182 · see citing works

Neural contributors to trauma resilience: a review of longitudinal neuroimaging studies

Roeckner, A. R., Oliver, K. I., Lebois, L. A. M., van Rooij, S. J. H., & Stevens, J. S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01633-y · Cited by 103 · see citing works

Laboratory models of post-traumatic stress disorder: The elusive bridge to translation

Dunsmoor, J. E., Cisler, J. M., Fonzo, G. A., Creech, S. K., & Nemeroff, C. B. (2022) · Neuron · doi:10.1016/j.neuron.2022.03.001 · Cited by 93 · see citing works

Endocannabinoids, cannabinoids and the regulation of anxiety

Petrie, G. N., Nastase, A. S., Aukema, R. J., & Hill, M. N. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108626 · Cited by 85 · see citing works

Using expectation violation models to improve the outcome of psychological treatments

Rief, W., Sperl, M. F. J., Braun-Koch, K., Khosrowtaj, Z., Kirchner, L., Schäfer, L. N., Schwarting, R. K. W., Teige‐Mocigemba, S., & Panitz, C. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102212 · Cited by 73 · see citing works

Genetic contributions to anxiety disorders: where we are and where we are heading

Ask, H., Cheesman, R., Jami, E. S., Levey, D. F., Purves, K. L., & Weber, H. (2021) · Psychological Medicine · doi:10.1017/s0033291720005486 · Cited by 72 · see citing works

Functional Neuroimaging in PTSD: From Discovery of Underlying Mechanisms to Addressing Diagnostic Heterogeneity

Neria, Y. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20121727 · Cited by 65 · see citing works

Neuroprotective effects of oleuropein: Recent developments and contemporary research

Butt, M. S., Tariq, U., Ul‐Haq, I., Naz, A., & Rizwan, M. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13967 · Cited by 65 · see citing works

Abnormal dynamic functional connectivity during fear extinction learning in PTSD and anxiety disorders

Wen, Z., Seo, J., Pace-Schott, E. F., & Milad, M. R. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01462-5 · Cited by 62 · see citing works

Alleviating anxiety and taming trauma: Novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

Singewald, N., Sartori, S. B., Reif, A., & Holmes, A. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109418 · Cited by 61 · see citing works

The clinical characterization of the adult patient with an anxiety or related disorder aimed at personalization of management

Stein, D. J., Craske, M. G., Rothbaum, B. O., Chamberlain, S. R., Fineberg, N. A., Choi, K. W., de Jonge, P., Baldwin, D. S., & Maj, M. (2021) · World Psychiatry · doi:10.1002/wps.20919 · Cited by 60 · see citing works

Neurobiology and Treatment of Posttraumatic Stress Disorder

Shalev, A. Y., Cho, D., & Marmar, C. R. (2024) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20240536 · Cited by 63 · see citing works

Measuring the biological embedding of racial trauma among Black Americans utilizing the RDoC approach

Carter, S. E., Gibbons, F. X., & Beach, S. R. H. (2021) · Development and Psychopathology · doi:10.1017/s0954579421001073 · Cited by 47 · see citing works

Therapeutic potential of ketamine for alcohol use disorder

Worrell, S. D., & Gould, T. J. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.05.006 · Cited by 47 · see citing works

Fear extinction learning modulates large-scale brain connectivity

Wen, Z., Chen, Z. S., & Milad, M. R. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118261 · Cited by 46 · see citing works

Novel Insights Into Pathological Anxiety and Anxiety-Related Disorders

Kalin, N. H. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20010057 · Cited by 42 · see citing works

Resting-state functional connectivity in anxiety disorders: a multicenter fMRI study

Langhammer, T., Hilbert, K., Adolph, D., Arolt, V., Bischoff, S., Böhnlein, J., Cwik, J. C., Dannlowski, U., Deckert, J., Domschke, K., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02768-2 · Cited by 34 · see citing works

Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD)

Bertolini, F., Robertson, L., Bisson, J. I., Meader, N., Churchill, R. C., Ostuzzi, G., Stein, D. J., Williams, T., & Barbui, C. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013443.pub2 · Cited by 35 · see citing works

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

Strom, N. I., Verhulst, B., Bacanu, S., Cheesman, R., Purves, K. L., Gedik, H., Mitchell, B. L., Kwong, A. S. F., Faucon, A. B., Singh, K., et al. (2026) · Nature Genetics · doi:10.1038/s41588-025-02485-8 · Cited by 77 · see citing works

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signalingPreprint

Strom, N. I., Verhulst, B., Bacanu, S., Cheesman, R., Purves, K. L., Gedik, H., Mitchell, B. L., Kwong, A. S. F., Faucon, A. B., Singh, K., et al. (2024) · medRxiv · doi:10.1101/2024.07.03.24309466 · Cited by 27 · see citing works

A multispecies probiotic accelerates fear extinction and inhibits relapse in mice: Role of microglia

Cui, X., Zhou, S., Xia, G., Chen, J., Jiang, L., Huang, J., & Tong, J. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108613 · Cited by 26 · see citing works

Contextual modulation of conditioned responses in humans: A review on virtual reality studies

Andreatta, M., & Pauli, P. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102095 · Cited by 27 · see citing works

Let's get wild: A review of free-ranging rat assays as context-enriched supplements to traditional laboratory models

Stryjek, R., Parsons, M. H., Fendt, M., Święcicki, J., & Bębas, P. (2021) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2021.109303 · Cited by 24 · see citing works

Pattern differentiation and tuning shift in human sensory cortex underlie long-term threat memory

You, Y., Novak, L. R., Clancy, K. J., & Li, W. (2022) · Current Biology · doi:10.1016/j.cub.2022.02.076 · Cited by 25 · see citing works

Impact of exogenous estradiol on task-based and resting-state neural signature during and after fear extinction in healthy women

Wen, Z., Hammoud, M. Z., Scott, J. C., Jimmy, J., Brown, L. A., Marin, M., Asnaani, A., Gur, R. C., Foa, E. B., & Milad, M. R. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01158-4 · Cited by 22 · see citing works

A non-canonical GABAergic pathway to the VTA promotes unconditioned freezing

Broussot, L., Contesse, T., Campos, R. C., Glangetas, C., Royon, L., Fofo, H., Lorivel, T., Georges, F. E., Fernández, S. P., & Barik, J. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01765-7 · Cited by 20 · see citing works

Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear

Sperl, M. F. J., Panitz, C., Skoluda, N., Nater, U. M., Pizzagalli, D. A., Hermann, C., & Mueller, E. M. (2022) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyac038 · Cited by 17 · see citing works

Role of noradrenergic arousal for fear extinction processes in rodents and humans

Bierwirth, P., & Stockhorst, U. (2022) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2022.107660 · Cited by 19 · see citing works

Vagus Nerve Stimulation as a Treatment for Fear and Anxiety in Individuals with Autism Spectrum Disorder

Shivaswamy, T., de Souza, R. R., Engineer, C. T., & McIntyre, C. K. (2022) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20220007 · Cited by 20 · see citing works

Oscillatory and non‐oscillatory brain activity reflects fear expression in an immediate and delayed fear extinction task

Bierwirth, P., Antov, M. I., & Stockhorst, U. (2023) · Psychophysiology · doi:10.1111/psyp.14283 · Cited by 16 · see citing works

Pharmakotherapie von Angsterkrankungen – leitliniengerechte Therapie und Neuentwicklungen

Zwanzger, P., Singewald, N., & Bandelow, B. (2021) · Der Nervenarzt · doi:10.1007/s00115-020-01051-3 · Cited by 15 · see citing works

Developing Multimodal Dynamic Functional Connectivity as a Neuroimaging Biomarker

Kundu, S., Jin, M., & Stevens, J. S. (2021) · Brain Connectivity · doi:10.1089/brain.2020.0900 · Cited by 15 · see citing works

Contributions of glucocorticoid receptors in cortical astrocytes to memory recallPreprint

Taylor, W. W., Imhoff, B. R., Sathi, Z. S., Liu, W. Y., Garza, K. M., & Dias, B. G. (2021) · Learning & Memory · doi:10.1101/lm.053041.120 · Cited by 15 · see citing works

Cholinergic signaling to CA1 astrocytes controls fear extinction

Li, Y., Li, L., Wang, Y., Li, X., Ding, X., Li, L., Fei, F., Zheng, Y., Li, C., Duan, S., et al. (2025) · Science Advances · doi:10.1126/sciadv.ads7191 · Cited by 15 · see citing works

Cortical Granularity Shapes the Organization of Afferent Paths to the Amygdala and Its Striatal Targets in Nonhuman Primate

McHale-Matthews, A., Cho, Y., & Fudge, J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0970-21.2021 · Cited by 14 · see citing works

Activating the attachment system modulates neural responses to threat in refugees with PTSD

Liddell, B., Malhi, G., Felmingham, K., Den, M., Das, P., Outhred, T., Nickerson, A., Askovic, M., Coello, M., Aroche, J., et al. (2021) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsab077 · Cited by 14 · see citing works

The Added Value of Crosstalk Between Developmental Circuit Neuroscience and Clinical Practice to Inform the Treatment of Adolescent Anxiety

Meyer, H. C., Fields, A., Vannucci, A., Gerhard, D. M., Bloom, P. A., Heleniak, C. M., Opendak, M. M., Sullivan, R. M., Tottenham, N., Callaghan, B. L., et al. (2022) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.02.002 · Cited by 15 · see citing works

β-adrenoceptors of the infra-limbic cortex mediate corticosterone-induced enhancement of acquisition and consolidation of fear memory extinction in rats

Meamar, M., Rashidy‐Pour, A., Vafaei, A. A., & Raise‐Abdullahi, P. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114310 · Cited by 14 · see citing works

VR for Studying the Neuroscience of Emotional Responses

Andreatta, M., Winkler, M. H., Collins, P., Gromer, D., Gall, D., Pauli, P., & Gamer, M. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_405 · Cited by 14 · see citing works

Revisiting sex differences in the acquisition and extinction of threat conditioning in humansPreprint

Wen, Z., Fried, J., Pace-Schott, E. F., Lazar, S. W., & Milad, M. R. (2022) · Learning & Memory · doi:10.1101/lm.053521.121 · Cited by 13 · see citing works

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates

Totty, M. S., Cervera‐Juanes, R. P., Bach, S. V., Ameur, L. B., Valentine, M. R., Simons, E. A., Romac, M. D., Trinh, H., Henderson, K., Rosario, I. D., et al. (2025) · Science Advances · doi:10.1126/sciadv.adw1029 · Cited by 11 · see citing works

Neuromodulation of inhibitory synaptic transmission in the basolateral amygdala during fear and anxiety

Fu, X., & Tasker, J. G. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1421617 · Cited by 10 · see citing works

Identification of a stress-responsive subregion of the basolateral amygdala in male rats

Aukema, R. J., Petrie, G. N., Matarasso, A. K., Baglot, S. L., Molina, L. A., Füzesi, T., Kadhim, S., Nastase, A. S., Reyes, I. R., Bains, J. S., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01927-x · Cited by 10 · see citing works

Integrating Aversive Memories in the Basolateral Amygdala

Liu, J., Totty, M. S., Bayer, H., & Maren, S. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.03.019 · Cited by 10 · see citing works

Self-construal modulates default mode network connectivity in refugees with PTSD

Liddell, B. J., Das, P., Malhi, G. S., Jobson, L., Lau, W., Felmingham, K. L., Nickerson, A., Askovic, M., Aroche, J., Coello, M., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.06.009 · Cited by 10 · see citing works

A 5-Factor Framework for Assessing Tobacco Use Disorder

Bucklin, M. (2021) · Tobacco Use Insights · doi:10.1177/1179173x21998355 · Cited by 9 · see citing works

Turning strains into strengths for understanding psychiatric disorders

Moore, S. J., Murphy, G. G., & Cazares, V. A. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0772-y · Cited by 9 · see citing works

Beyond Fear, Extinction, and Freezing: Strategies for Improving the Translational Value of Animal Conditioning Research

Cain, C. K. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_434 · Cited by 10 · see citing works

Early pharmacological interventions for prevention of post-traumatic stress disorder (PTSD) in individuals experiencing acute traumatic stress symptoms

Bertolini, F., Robertson, L., Bisson, J. I., Meader, N., Churchill, R. C., Ostuzzi, G., Stein, D. J., Williams, T., & Barbui, C. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013613.pub2 · Cited by 9 · see citing works

Executive Functioning in Pediatric Anxiety and Its Relationship to Selective Serotonin Reuptake Inhibitor Treatment Response: A Double-Blind, Placebo-Controlled Trial

Baumel, W. T., Mills, J. A., Schroeder, H. K., Specht, A. M., Rothenberg, R., Peris, T. S., & Strawn, J. R. (2022) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2022.0012 · Cited by 7 · see citing works

Post-traumatic stress disorder

Ressler, K. J., Rothbaum, B. O., Schnurr, P. P., Binder, E., Moreland-Capuia, A. R., Nievergelt, C. M., Koenen, K. C., Seedat, S., Shalev, A. Y., Marmar, C. R., et al. (2026) · Nature Reviews Disease Primers · doi:10.1038/s41572-026-00701-1 · Cited by 6 · see citing works

Acute and chronic cannabis vapor exposure produces immediate and delayed impacts on phases of fear learning in a sex specific manner

Lightfoot, S. H. M., Nastase, A. S., Cesar, G. C. L., Hume, C., Gom, R. C., Teskey, G. C., & Hill, M. N. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06748-4 · Cited by 5 · see citing works

Animal models built for women’s brain health: Progress and potential

Morrison, K. E. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2020.100872 · Cited by 5 · see citing works

Development-Dependent Plasticity in Vasoactive Intestinal Polypeptide Neurons in the Infralimbic Cortex

Collins, S. A., & Ninan, I. (2021) · Cerebral Cortex Communications · doi:10.1093/texcom/tgab007 · Cited by 5 · see citing works

Probing Neuro-Endocrine Interactions Through Remote Magnetothermal Adrenal Stimulation

Maeng, L. Y., Rosenfeld, D., Simandl, G. J., Koehler, F., Senko, A. W., Moon, J., Varnavides, G., Murillo, M. F., Reimer, A. E., Wald, A., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.901108 · Cited by 6 · see citing works

Functional anatomy of the limbic system structures involved in the development of post-traumatic stress disorder: analysis of anatomical and clinical studies

Nikolenko, V. N., Osadchiy, A. S., Lobanova, A., Isakova, T. A., Zharov, N. A., & Zharova, N. V. (2024) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2024-2-69-75 · Cited by 4 · see citing works

Gray matter associations with extinction-induced neural activation in patients with anxiety disorders

Badarnee, M., Wen, Z., Nassar, N., & Milad, M. R. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.05.015 · Cited by 4 · see citing works

Classical Conditioning

Hermann, C., & Sperl, M. F. J. (2023) · Autism and child psychopathology series · doi:10.1007/978-3-031-24926-6_21 · Cited by 4 · see citing works

Neuromodulation of Fear and Anxiety Circuits

Brown, J. A., Clancy, K. J., & Li, W. (2025) · Current topics in behavioral neurosciences · doi:10.1007/7854_2024_573 · Cited by 3 · see citing works

Genomic analysis of firework fear and noise reactivity in standard poodles

Handegård, K. W., Storengen, L. M., Joergensen, D., & Lingaas, F. (2023) · Canine Medicine and Genetics · doi:10.1186/s40575-023-00125-0 · Cited by 3 · see citing works

Modulation of Fear Extinction by Non‐Invasive Brain Stimulation: Systematic Review and Meta‐Analysis

Ye, Z., Lin, J., Dou, H., Zhang, H., Cao, Y., & Lei, Y. (2025) · Psychophysiology · doi:10.1111/psyp.14763 · Cited by 3 · see citing works

Biomarkers of Anxiety Acquisition and Generalization in Virtual Reality Experiments

Genheimer, H., Pauli, P., & Andreatta, M. (2022) · Zeitschrift für Klinische Psychologie und Psychotherapie · doi:10.1026/1616-3443/a000658 · Cited by 2 · see citing works

Evolutionary Psychiatry

Nesse, R. M., & Stein, D. J. (2023) · Springer eBooks · doi:10.1007/978-3-030-42825-9_71-1 · Cited by 2 · see citing works

Causality Between Irritable Bowel Syndrome and Suicide Attempt: A Mendelian Randomization Study

Deng, Z., Wang, K., & Hou, T. (2025) · Brain and Behavior · doi:10.1002/brb3.70513 · Cited by 2 · see citing works

Effectiveness of Finnish SISU training in enhancing prehospital personnels’ work performance: A randomised controlled pilot study

Vihonen, H., Karvonen, J., Gustafsberg, H., Huhta, J., Kangasniemi, H., Jama, T., & Hoppu, S. (2025) · BMC Emergency Medicine · doi:10.1186/s12873-025-01235-7 · Cited by 1 · see citing works

Transcriptomic Architecture of Weak Versus Strong Contextual Fear Extinction Learning Uncovers Extinction-Suppressive Role of TIA1

Bonilla, M. I., Lee, H.-L., Foster, S., Kim, I.-J., & Rudenko, A. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100591 · Cited by 1 · see citing works

Maternal Stress During Pregnancy Induces Higher Anxiety-Like Behavior in Male Mice Offspring Under Acute Stress by Upregulating CRF/CRFR1 and Driving Time-Specific Activation of the MHb-IPN Circuit

Wang, Y., Zhao, J., Wang, Y., Du, Z., Wang, L., Ma, Z., Sun, S., Qu, X., Geng, X., Yan, J., et al. (2026) · Neuroscience Bulletin · doi:10.1007/s12264-025-01575-1 · Cited by 2 · see citing works

Multimodal Spatiotemporal Dynamics of Frontomedial Theta and BOLD Signal Reveal Functional Roles in Updating and Suppressing Aversive Memory During Fear Extinction

Gabdulkhakov, A., Sperl, M. F. J., Merz, C. J., Klatt, L., Fraenz, C., & Genç, E. (2026) · Psychophysiology · doi:10.1111/psyp.70281 · Cited by 1 · see citing works

Top-down medial prefrontal cortex-to-hypothalamic paraventricular nucleus circuit regulates social avoidance and conditioned fear in male mice

Wang, Y., Pan, X., Wu, B., Li, D.-Y., Wang, S., Qin, X., Shan, Q., Chen, P., Hu, P., Wang, H., et al. (2026) · Cell Discovery · doi:10.1038/s41421-026-00893-6 · Cited by 1 · see citing works

Context-Dependent Responses to the Spread of COVID-19 Among National and International Students During the First Lockdown: An Online Survey

Andreatta, M., Jongerling, J., & Wieser, M. J. (2023) · Disaster Medicine and Public Health Preparedness · doi:10.1017/dmp.2023.118 · Cited by 1 · see citing works

Noise reactivity and firework fear in dogs

Handegård, K. W. (2023) · Companion animal · doi:10.12968/coan.2023.0041 · Cited by 1 · see citing works

Golden Snub-Nosed Monkeys: Potential Primate Paradigm in Post-Traumatic Stress Disorder Research

Zhao, H., Wang, Y., Li, J., Li, N., Zhou, W., Wang, C., & Li, B. (2025) · Biology · doi:10.3390/biology14020156 · Cited by 1 · see citing works

Probing Neuro-Endocrine Interactions Through Wireless Magnetothermal Stimulation of Peripheral OrgansPreprint

Maeng, L. Y., Rosenfeld, D., Simandl, G. J., Koehler, F., Senko, A. W., Moon, J., Varnavides, G., Murillo, M. F., Reimer, A. E., Wald, A., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.24.449506 · Cited by 1 · see citing works

Pattern separation and tuning shift in human sensory cortex underlie fear memoryPreprint

You, Y., Novak, L. R., Clancy, K., & Li, W. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.27.457990 · Cited by 1 · see citing works

Editorial: Neural circuits and neuroendocrine mechanisms of major depressive disorder and premenstrual dysphoric disorder: Toward precise targets for translational medicine and drug development

Wei, S., Wang, F., Liu, J., & Wang, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.983604 · Cited by 1 · see citing works

Individual variability and sexually dimorphic fear memory-related effects of anxiety on fear extinction in inbred mouse modelPreprint

Rudenko, A. (2023) · doi:10.31234/osf.io/b84zx · Cited by 1 · see citing works

Sex-specific calibration of memory recall by glucocorticoid receptors on cortical astrocytesPreprint

Taylor, W., Imhoff, B., Sathi, Z., Garza, K., & Dias, B. G. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.01.278556

Neural vulnerability and hurricane-related media predict posttraumatic stress in youthPreprint

Dick, A. S., Silva, K., González, R., Sutherland, M. T., Laird, A. R., Thompson, W. K., Tapert, S. F., Squeglia, L. M., Gray, K. M., Nixon, S. J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.27.271056

DESMARCAJE DEL PATRÓN CATALOGADO DE IMAGEN CEREBRAL PARA DESAPREHENDER DESDE UNA CONCEPTUALIZACIÓN FILOSÓFICA

Pérez, G. A. (2021) · The Biologist · doi:10.24039/rtb20211921176

Sexually dimorphic interplay between anxiety-related phenotype and fear memory extinctionPreprint

Bonilla, M. I., Lee, H.-L., Kim, I.-J., & Rudenko, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.17.460842

Anxiety and Stress-Related Disorders

(2021) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.19201

Translationale Forschung bietet Chancen für das Verstehen von Angststörungen

(2020) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/a-1163-9296

Context-dependent responses to the spread of COVID-19 among national and international students during the first lockdownPreprint

Andreatta, M., Jongerling, J., & Wieser, M. J. (2022) · doi:10.31219/osf.io/zrjeb

Brain-based transcriptomic architecture associated with high and low efficacy of fear extinction learningPreprint

Rudenko, A. (2023) · doi:10.31234/osf.io/qrmxp

Evolutionary Psychiatry

Nesse, R. M., & Stein, D. J. (2024) · Springer eBooks · doi:10.1007/978-3-030-51366-5_71

Interpeduncular GABAergic neuron function controls threat processing and innate defensive adaptive learningPreprint

Molas, S., Williams, E., Snively, L., O'Meara, B. R., Jacobs, H., Kolb, M., Zhao-Shea, R., Baratta, M. V., & Tapper, A. R. (2024) · Research Square · doi:10.21203/rs.3.rs-4661779/v1

Network Localization of Brain Stimulation Targets for Trait AnxietyPreprint

Siddiqi, S., Klingbeil, J., Webler, R. D., Kratter, I. H., Blumberger, D. M., Fox, M., George, M. S., Grafman, J. H., Pascual‐Leone, Á., Pines, A. R., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.5001997

A formal model of anxiety disorders based on the neural circuit dynamics of the fear and extinction circuitsPreprint

Rubin, A. L., & Walth, M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.20.633839 · Cited by 1 · see citing works

Feeling Blue: the Impact of Body-Worn Cameras on Police Officers' Well-Being During Investigations of Misconduct

Brown, A. S. (2025) · doi:10.22215/etd/2025-16681

Additional file 2 of Genomic analysis of firework fear and noise reactivity in standard poodles

Handegård, K. W., Storengen, L. M., Joergensen, D., & Lingaas, F. (2023) · Figshare · doi:10.6084/m9.figshare.22624619

Additional file 1 of Genomic analysis of firework fear and noise reactivity in standard poodles

Handegård, K. W., Storengen, L. M., Joergensen, D., & Lingaas, F. (2023) · Figshare · doi:10.6084/m9.figshare.22624616

Hormone-Tuned Fear Circuits: Estrous Regulation of Corticotropin-Releasing Factor Neurons in the Bed Nucleus of the Stria Terminalis

Marin‐Blasco, I., & Andero, R. (2026) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.11.001

Insomnia as a Disorder of Threat Perception: Hyperarousal, Extinction, and Trauma-Informed Implications for CBT-I

Forman, B. D. (2026) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-026-09725-w

Is the representation of fear distributed across the whole brain?Preprint

Côté, M., Valevicius, D., Davignon, L., Marin, M., & Taschereau‐Dumouchel, V. (2026) · Research Square · doi:10.21203/rs.3.rs-9456965/v1

Neural alterations in Pavlovian reversal learning link childhood trauma and transdiagnostic anxiety in youth

DeCross, S. N., Kribakaran, S., Odriozola, P., Sheridan, M. A., Tottenham, N., Gee, D. G., & McLaughlin, K. A. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.122012

Synaptic, cellular, and circuit mechanisms underlying sex differences in behaviors

Ninan, I. (2026) · Biology of Sex Differences · doi:10.1186/s13293-026-00931-8

Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain

Oakley, R. H., Sueyoshi, T., Ramamoorthy, S., Nikolova, V. D., Goulding, D. R., LI, J., Ray, M. K., Moy, S. S., & Cidlowski, J. A. (2026) · The FASEB Journal · doi:10.1096/fj.202601316r

Posttraumatic Stress Disorder (PTSD) NAD/Sirtuin Deficiency and SARM1-Mediated Synaptic Vulnerability: Evidence for Accelerated Brain Aging Subtypes

Cheung, N. (2026) · Cureus · doi:10.7759/cureus.110755

Translational Approaches to Anxiety: Focus on Genetics, Fear Extinction and Brain Imaging

Erhardt, A., & Spoormaker, V. I. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0417-9 · Cited by 25 · see citing works

Lost in translation: How to upgrade fear memory research

Flores, Á., Fullana, M. À., Soriano-Mas, C., & Andero, R. (2018) · Molecular Psychiatry · doi:10.1038/s41380-017-0006-0 · Cited by 59 · see citing works

Understanding the heterogeneity of anxiety using a translational neuroscience approach

Drzewiecki, C. M., & Fox, A. S. (2024) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-024-01162-3 · Cited by 33 · see citing works

Neuroscience of fear extinction: Implications for assessment and treatment of fear-based and anxiety related disorders

Milad, M. R., Rosenbaum, B. L., & Simon, N. M. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.08.006 · Cited by 161 · see citing works

Towards new approaches to disorders of fear and anxiety

Dias, B. G., Banerjee, S. B., Goodman, J. V., & Ressler, K. J. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.01.013 · Cited by 79 · see citing works