Cited by 1,201Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and TreatmentsAcute Ischemic Stroke Management

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Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers

Chui, H. C., Victoroff, J. I., Margolin, D., Jagust, W., Shankle, R., Katzman, R.·1992·Neurology

DOI 10.1212/wnl.42.3.473

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Abstract

Accurate diagnosis of vascular dementia is important for the recognition of underlying pathophysiology and the institution of appropriate therapy. It is also important for the determination of the incidence and prevalence of not only vascular dementia but also Alzheimer's disease (AD), since differentiating between these two entities is often problematic. The State of California Alzheimer's Disease Diagnostic and Treatment Centers (ADDTC) herein propose criteria for the diagnosis of ischemic vascular dementia (IVD). These criteria broaden the conceptualization of vascular dementia, include the results of neuroimaging studies, emphasize the importance of neuropathologic confirmation, refine nosology, and identify areas that require further research. Parallel use of the proposed definitions of "possible" and "mixed" categories in the diagnosis of both AD and IVD would ensure compatibility between the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) criteria for AD and the ADDTC criteria for IVD. Uniform classification of subtypes of IVD will improve the generalizability of individual studies and aid in multicenter collaborations.

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Authors: Chui, H. C., Victoroff, J. I., Margolin, D., Jagust, W., Shankle, R., & Katzman, R.
Affiliations: University of Southern California (US)
ORCID: Chui, H. C.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1992-03
Volume: 42
Issue: 3
Pages: 473-473
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.42.3.473
OpenAlex: W1989294823
Cited by: 1,201
References: 0
Citations by year: 2026: 11 · 2025: 9 · 2024: 20 · 2023: 13 · 2022: 17 · 2021: 25 · 2020: 21 · 2019: 20 · 2018: 15 · 2017: 34 · 2016: 21 · 2015: 25 · 2014: 24 · 2013: 43 · 2012: 51
FWCI: 21.59
Type: journal article
Language: en
Open access: closed
Locations: Neurology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01ag007624-05)
National Institute on Aging (1P50-AG-05142, R01 AG07624, P50AG005142)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Keywords: diagnostic criteria, Alzheimer's disease, differential diagnosis, neuroimaging, disease classification, mixed dementia
MeSH terms: Brain Ischemia, Cerebrovascular Disorders, Cognition Disorders, Humans, Dementia, Vascular

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Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers

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