Molecular and cellular mechanisms of tooth development, homeostasis and repair

Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

Santos, A. G., da Rocha, G. O., & de Andrade, J. B. (2019) · Scientific Reports · doi:10.1038/s41598-018-37186-2 · Cited by 8,495

Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis

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Asymmetric paralog evolution between the “cryptic” gene Bmp16 and its well-studied sister genes Bmp2 and Bmp4

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β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin

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Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine

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Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

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WNT Signals Are Required for the Initiation of Hair Follicle Development

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Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

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BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling

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Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

Vainio, S. J., Karavanova, I. D., Jowett, A. K., & Thesleff, I. (1993) · Cell · doi:10.1016/0092-8674(93)90678-j · Cited by 924

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

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Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities

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Identification and Specification of the Mouse Skeletal Stem Cell

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X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein

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Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer

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The efficacy of mesenchymal stem cells to regenerate and repair dental structures

Shi, S., Bartold, P., Miura, M., Seo, B., Robey, P., & Gronthos, S. (2005) · Orthodontics & Craniofacial Research · doi:10.1111/j.1601-6343.2005.00331.x · Cited by 540

Localization of Putative Stem Cells in Dental Epithelium and Their Association with Notch and Fgf Signaling

Harada, H., Kettunen, P., Jung, H.-S., Mustonen, T., Wang, Y. A., & Thesleff, I. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.1.105 · Cited by 517

Quantifying cell-generated mechanical forces within living embryonic tissues

Campàs, O., Mammoto, T., Hasso, S., Sperling, R. A., O'Connell, D., Bischof, A. G., Maas, R., Weitz, D. A., Mahadevan, L., & Ingber, D. E. (2014) · Nature Methods · doi:10.1038/nmeth.2761 · Cited by 479

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

Zhao, H., Feng, J., Seidel, K., Shi, S., Klein, O., Sharpe, P., & Chai, Y. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2013.12.013 · Cited by 461

The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot

Jernvall, J., Åberg, T., Kettunen, P., Keränen, S., & Thesleff, I. (1998) · Development · doi:10.1242/dev.125.2.161 · Cited by 445

Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene

Jernvall, J., Kettunen, P., Karavanova, I., Martin, L. B., & Thesleff, I. (1994) · The International Journal of Developmental Biology · doi:10.1387/ijdb.7848830 · Cited by 435

Glial origin of mesenchymal stem cells in a tooth model system

Kaukua, N., Shahidi, M. K., Konstantinidou, C., Dyachuk, V., Kaucka, M., Furlan, A., An, Z., Wang, L., Hultman, I., Ährlund-Richter, L., et al. (2014) · Nature · doi:10.1038/nature13536 · Cited by 421

Dual origin of mesenchymal stem cells contributing to organ growth and repair

Feng, J., Mantesso, A., De Bari, C., Nishiyama, A., & Sharpe, P. T. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015449108 · Cited by 410

The enamel knot as a signaling center in the developing mouse tooth

Vaahtokari, A., Åberg, T., Jernvall, J., Keränen, S., & Thesleff, I. (1996) · Mechanisms of Development · doi:10.1016/0925-4773(95)00459-9 · Cited by 394

Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

Liu, F., Chu, E. Y., Watt, B., Zhang, Y., Gallant, N. M., Andl, T., Yang, S. H., Lu, M.-M., Piccolo, S., Schmidt-Ullrich, R., et al. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2007.10.016 · Cited by 381

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling

Järvinen, E., Salazar-Ciudad, I., Birchmeier, W., Taketo, M. M., Jernvall, J., & Thesleff, I. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607289103 · Cited by 379

Gene defect in ectodermal dysplasia implicates a death domain adapter in development

Headon, D. J., Emmal, S. A., Ferguson, B. M., Tucker, A. S., Justice, M. J., Sharpe, P. T., Zonana, J., & Overbeek, P. A. (2001) · Nature · doi:10.1038/414913a · Cited by 378

The tortoise and the hair: slow-cycling cells in the stem cell race

Fuchs, E. (2009) · Cell · doi:10.1016/j.cell.2009.05.002 · Cited by 371

Tooth shape formation and tooth renewal: evolving with the same signals

Jernvall, J., & Thesleff, I. (2012) · Development · doi:10.1242/dev.085084 · Cited by 359

Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

Haegebarth, A., & Clevers, H. (2009) · The American Journal of Pathology · doi:10.2353/ajpath.2009.080758 · Cited by 353

Inflammation and Regeneration in the Dentin-Pulp Complex: A Double-edged Sword

Cooper, P. R., Holder, M. J., & Smith, A. J. (2014) · Journal of Endodontics · doi:10.1016/j.joen.2014.01.021 · Cited by 320

Mineralized tissue and vertebrate evolution: The secretory calcium-binding phosphoprotein gene cluster

Kawasaki, K., & Weiss, K. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0638023100 · Cited by 314

Dental mesenchymal stem cells

Sharpe, P. T. (2016) · Development · doi:10.1242/dev.134189 · Cited by 310

Enamel Knots as Signaling Centers Linking Tooth Morphogenesis and Odontoblast Differentiation

Thesleff, I., Keranen, S., & Jernvall, J. (2001) · Advances in Dental Research · doi:10.1177/08959374010150010401 · Cited by 302

Regulation of Mammalian Tooth Cusp Patterning by Ectodin

Kassai, Y., Munne, P., Hotta, Y., Penttilä, E., Kavanagh, K., Ohbayashi, N., Takada, S., Thesleff, I., Jernvall, J., & Itoh, N. (2005) · Science · doi:10.1126/science.1116848 · Cited by 298

Sprouty Genes Control Diastema Tooth Development via Bidirectional Antagonism of Epithelial-Mesenchymal FGF Signaling

Klein, O. D., Minowada, G., Peterkova, R., Kangas, A., Yu, B. D., Lesot, H., Peterka, M., Jernvall, J., & Martin, G. R. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.05.014 · Cited by 287

Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1

Narayanan, K., Srinivas, R., Ramachandran, A., Hao, J., Quinn, B., & George, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081075198 · Cited by 276

Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot

Laurikkala, J., Kassai, Y., Pakkasjärvi, L., Thesleff, I., & Itoh, N. (2003) · Developmental Biology · doi:10.1016/j.ydbio.2003.08.011 · Cited by 270

Photoactivation of Endogenous Latent Transforming Growth Factor–β1 Directs Dental Stem Cell Differentiation for Regeneration

Arany, P. R., Cho, A., Hunt, T. D., Sidhu, G., Shin, K., Hahm, E., Huang, G. X., Weaver, J., Chen, A. C.-H., Padwa, B. L., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008234 · Cited by 267

Matrix Macromolecules in Hard Tissues Control the Nucleation and Hierarchical Assembly of Hydroxyapatite

Gajjeraman, S., Narayanan, K., Hao, J., Qin, C., & George, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m604732200 · Cited by 259

Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices

Yang, H., Adam, R. C., Ge, Y., Hua, Z. L., & Fuchs, E. (2017) · Cell · doi:10.1016/j.cell.2017.03.038 · Cited by 257

Dental Enamel Development: Proteinases and Their Enamel Matrix Substrates

Bartlett, J. D. (2013) · ISRN Dentistry · doi:10.1155/2013/684607 · Cited by 245

Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development

Chen, J., Lan, Y., Baek, J.-A., Gao, Y., & Jiang, R. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.07.015 · Cited by 242

An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

Hu, J. K.-H., Du, W., Shelton, S. J., Oldham, M. C., DiPersio, C. M., & Klein, O. D. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2017.03.023 · Cited by 239

Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors

Juuri, E., Saito, K., Ahtiainen, L., Seidel, K., Tummers, M., Hochedlinger, K., Klein, O. D., Thesleff, I., & Michon, F. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.05.012 · Cited by 235

Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood

Wang, X.-P., O'Connell, D. J., Lund, J. J., Saadi, I., Kuraguchi, M., Turbe-Doan, A., Cavallesco, R., Kim, H., Park, P. J., Harada, H., et al. (2009) · Development · doi:10.1242/dev.033803 · Cited by 216

Root or crown: a developmental choice orchestrated by the differential regulation of the epithelial stem cell niche in the tooth of two rodent species

Tummers, M., & Thesleff, I. (2003) · Development · doi:10.1242/dev.00332 · Cited by 213

Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Ahn, Y., Sanderson, B. W., Klein, O. D., & Krumlauf, R. (2010) · Development · doi:10.1242/dev.054668 · Cited by 213

An Integrated Gene Regulatory Network Controls Stem Cell Proliferation in Teeth

Wang, X.-P., Suomalainen, M., Felszeghy, S., Zelarayan, L. C., Alonso, M. T., Plikus, M. V., Maas, R. L., Chuong, C.-M., Schimmang, T., & Thesleff, I. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050159 · Cited by 213

Cusp Patterning Defect in Tabby Mouse Teeth and Its Partial Rescue by FGF

Pispa, J., Jung, H.-S., Jernvall, J., Kettunen, P., Mustonen, T., Tabata, M. J., Kere, J., & Thesleff, I. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9514 · Cited by 197

Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus

Kuraguchi, M., Wang, X.-P., Bronson, R. T., Rothenberg, R., Ohene-Baah, N. Y., Lund, J. J., Kucherlapati, M., Maas, R. L., & Kucherlapati, R. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020146 · Cited by 186

Role of Mechanical Factors in Fate Decisions of Stem Cells

Li, D., Zhou, J., Chowdhury, F., Cheng, J., Wang, N., & Wang, F. (2011) · Regenerative Medicine · doi:10.2217/rme.11.2 · Cited by 181

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor

Seidel, K., Ahn, C. P., Lyons, D., Nee, A., Ting, K., Brownell, I., Cao, T., Carano, R. A. D., Curran, T., Schober, M., et al. (2010) · Development · doi:10.1242/dev.056358 · Cited by 177

Control of ameloblast differentiation

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Sox2 marks epithelial competence to generate teeth in mammals and reptiles

Juuri, E., Jussila, M., Seidel, K., Holmes, S., Wu, P., Richman, J., Heikinheimo, K., Chuong, C.-M., Arnold, K., Hochedlinger, K., et al. (2013) · Development · doi:10.1242/dev.089599 · Cited by 169

Replaying evolutionary transitions from the dental fossil record

Harjunmaa, E., Seidel, K., Häkkinen, T. J., Renvoisé, É., Corfe, I. J., Kallonen, A., Zhang, Z., Evans, A. R., Mikkola, M. L., Salazar‐Ciudad, I., et al. (2014) · Nature · doi:10.1038/nature13613 · Cited by 157

Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis

Nakatomi, M., Wang, X., Key, D., Lund, J. J., Turbé-Doan, A., Kist, R., Aw, A., Chen, Y., Maas, R. L., & Peters, H. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.01.031 · Cited by 155

BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor

Biehs, B., Hu, J. K., Strauli, N. B., Sangiorgi, E., Jung, H., Heber, R.-P., Ho, S. P., Goodwin, A. F., Dasen, J. S., Capecchi, M. R., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2766 · Cited by 150

Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption

Takahashi, A., Nagata, M., Gupta, A., Matsushita, Y., Yamaguchi, T., Mizuhashi, K., Maki, K., Ruellas, A. C. D. O., Cevidanes, L., Kronenberg, H. M., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1810200115 · Cited by 143

BMP-SHH Signaling Network Controls Epithelial Stem Cell Fate via Regulation of Its Niche in the Developing Tooth

Li, J., Feng, J., Liu, Y., Ho, T., Grimes, W., Ho, H. A., Park, S., Wang, S., & Chai, Y. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.02.021 · Cited by 140

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/β‐catenin signaling in the epithelial stem cells

Suomalainen, M., & Thesleff, I. (2009) · Developmental Dynamics · doi:10.1002/dvdy.22106 · Cited by 134

ENAM Mutations in Autosomal-dominant Amelogenesis Imperfecta

Kim, J., Seymen, F., Lin, B. P.-J., Kiziltan, B., Gençay, K., Simmer, J. P., & Hu, J. C. ‐. (2005) · Journal of Dental Research · doi:10.1177/154405910508400314 · Cited by 128

Deletion of ameloblastin exon 6 is associated with amelogenesis imperfecta

Poulter, J. A., Murillo, G., Brookes, S. J., Smith, C. E. L., Parry, D. A., Silva, S., Kirkham, J., Inglehearn, C. F., & Mighell, A. J. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu247 · Cited by 127

EVOLUTION OF DENTAL REPLACEMENT IN MAMMALS

Luo, Z., Kielan‐Jaworowska, Z., & Cifelli, R. L. (2004) · Bulletin of Carnegie Museum of Natural History · doi:10.2992/0145-9058(2004)36[159:eodrim]2.0.co;2 · Cited by 123

Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia

Massink, M. P. G., Créton, M. A., Spanevello, F., Fennis, W. M. M., Cune, M. S., Savelberg, S. M. C., Nijman, I. J., Maurice, M. M., van den Boogaard, M. H., & van Haaften, G. W. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.08.014 · Cited by 118

Dentin Matrix Protein 1 Regulates Dentin Sialophosphoprotein Gene Transcription during Early Odontoblast Differentiation

Narayanan, K., Gajjeraman, S., Ramachandran, A., Hao, J., & George, A. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600714200 · Cited by 117

Transcription Factor Epiprofin Is Essential for Tooth Morphogenesis by Regulating Epithelial Cell Fate and Tooth Number

Nakamura, T., de Vega, S., Fukumoto, S., Jiménez‐Rojo, L., Unda, F. J., & Yamada, Y. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m708388200 · Cited by 116

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs

Michon, F., Tümmers, M., Kyyrönen, M., Frilander, M. J., & Thesleff, I. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.01.019 · Cited by 113

A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage

Sharir, A., Marangoni, P., Žilionis, R., Wan, M., Wald, T., Hu, J. K., Kawaguchi, K., Castillo‐Azofeifa, D., Epstein, L., Harrington, K., et al. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0378-2 · Cited by 112

A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors

An, Z., Sabalić, M., Bloomquist, R. F., Fowler, T. E., Streelman, J. T., & Sharpe, P. T. (2018) · Nature Communications · doi:10.1038/s41467-017-02785-6 · Cited by 111

Amelogenin p.M1T and p.W4S Mutations Underlying Hypoplastic X-linked Amelogenesis Imperfecta

Kim, J., Simmer, J. P., Hu, Y., Lin, B., Boyd, C., Wright, J. T., Yamada, C. J. M., Rayes, S. K., Feigal, R. J., & Hu, J. C. ‐. (2004) · Journal of Dental Research · doi:10.1177/154405910408300505 · Cited by 105

MicroRNAs Play a Critical Role in Tooth Development

Cao, H., Wang, J., Li, X., Florez, S. L., Huang, Z.-P., Venugopalan, S. R., Elangovan, S., Skobe, Z., Margolis, H. C., Martin, J. F., et al. (2010) · Journal of Dental Research · doi:10.1177/0022034510369304 · Cited by 102

Taurodontism, variations in tooth number, and misshapened crowns inWnt10anull mice and human kindreds

Yang, J., Wang, S., Choi, M., Reid, B. M., Hu, Y., Lee, Y., Herzog, C. R., Kim‐Berman, H., Lee, M., Benke, P. J., et al. (2014) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.111 · Cited by 100

Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling

Häärä, O., Harjunmaa, E., Lindfors, P. H., Huh, S., Fliniaux, I., Åberg, T., Jernvall, J., Ornitz, D. M., Mikkola, M. L., & Thesleff, I. (2012) · Development · doi:10.1242/dev.079558 · Cited by 100

The eternal tooth germ is formed at the apical end of continuously growing teeth

Ohshima, H., Nakasone, N., Hashimoto, E., et al. (2004) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2004.09.008 · Cited by 92

Decellularized Tooth Bud Scaffolds for Tooth Regeneration

Zhang, W., Vazquez, B., Oreadi, D., & Yelick, P. C. (2017) · Journal of Dental Research · doi:10.1177/0022034516689082 · Cited by 87

Involvement of matrix metalloproteinases in the onset of dentin mineralization

Fanchon, S., Bourd, K., Septier, D., Everts, V. E., Beertsen, W., Ménashi, S., & Goldberg, M. (2004) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.2004.00120.x · Cited by 85

Wntless Regulates Dentin Apposition and Root Elongation in the Mandibular Molar

Bae, C. H., Kim, T. H., Ko, S.-O., Lee, J., Yang, X. Y., & Cho, E. S. (2015) · Journal of Dental Research · doi:10.1177/0022034514567198 · Cited by 85

Axin2-expressing cells differentiate into reparative odontoblasts via autocrine Wnt/β-catenin signaling in response to tooth damage

Babb, R. C., Chandrasekaran, D., Neves, V. C. M., & Sharpe, P. T. (2017) · Scientific Reports · doi:10.1038/s41598-017-03145-6 · Cited by 83

Biology Explaining Tooth Repair and Regeneration: A Mini-Review

Balic, A. (2018) · Gerontology · doi:10.1159/000486592 · Cited by 80

Stratum intermedium lineage diverges from ameloblast lineage via Notch signaling

Harada, H., Ichimori, Y., Yokohama‐Tamaki, T., Ohshima, H., Kawano, S., Katsube, K., & Wakisaka, S. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.12.053 · Cited by 78

Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation

Noda, S., Kawashima, N., Yamamoto, M., Hashimoto, K., Nara, K., Sekiya, I., & Okiji, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-41741-w · Cited by 78

Fibroblast growth factor signaling in mammalian tooth development

Li, C., Procházka, J., Goodwin, A. F., & Klein, O. D. (2013) · Odontology · doi:10.1007/s10266-013-0142-1 · Cited by 76

Early epithelial signaling center governs tooth budding morphogenesis

Ahtiainen, L., Uski, I., Thesleff, I., & Mikkola, M. L. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201512074 · Cited by 75

Mesenchymal Wnt/β-catenin signaling limits tooth number

Järvinen, E., Shimomura-Kuroki, J., Balic, A., Jussila, M., & Thesleff, I. (2018) · Development · doi:10.1242/dev.158048 · Cited by 71

Mechanical constraint from growing jaw facilitates mammalian dental diversity

Renvoisé, É., Kavanagh, K. D., Lazzari, V., Häkkinen, T. J., Rice, R., Pantalacci, S., Salazar‐Ciudad, I., & Jernvall, J. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1707410114 · Cited by 68

TGF-β type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner

Zhao, H., Oka, K., Bringas, P., Kaartinen, V., & Chai, Y. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.03.045 · Cited by 67

Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth

Li, J., Chatzeli, L., Panousopoulou, E., Tucker, A. S., & Green, J. B. A. (2016) · Development · doi:10.1242/dev.130187 · Cited by 67

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sun, Z. Q., Yu, W., Navarro, M. S., Sweat, M., Eliason, S. L., Sharp, T., Liu, H., Seidel, K., Zhang, L., Moreno, M., et al. (2016) · Development · doi:10.1242/dev.138883 · Cited by 64

Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling

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A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation

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Traf6 is essential for murine tooth cusp morphogenesis

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Reactionary dentinogenesis after applying restorative materials and bioactive dentin matrix molecules as liners in deep cavities prepared in nonhuman primate teeth

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Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis

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Over- and Ectopic Expression of Wnt3 Causes Progressive Loss of Ameloblasts in Postnatal Mouse Incisor Teeth

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Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis

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Multiple modes of Lrp4 function in modulation of Wnt/β-catenin signaling during tooth development

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In Vitro Conditioning Determines the Capacity of Dental Pulp Stem Cells to Function as Pericyte-Like Cells

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FGF10 Maintains Stem Cell Population During Mouse Incisor Development

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Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation

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Revitalising the rudimentary replacement dentition in the mouse

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Alk5-Mediated Transforming Growth Factor β Signaling Acts Upstream of Fibroblast Growth Factor 10 To Regulate the Proliferation and Maintenance of Dental Epithelial Stem Cells

Zhao, H., Li, S., Han, D. K., Kaartinen, V., & Chai, Y. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.01439-10 · Cited by 45

Specificity Protein 7 Is Required for Proliferation and Differentiation of Ameloblasts and Odontoblasts

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The evolution of growth patterns in mammalian versus nonmammalian cynodonts

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Perivascular Stem Cells at the Tip of Mouse Incisors Regulate Tissue Regeneration

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Longer in the tooth, shorter in the record? The evolutionary correlates of hypsodonty in Neogene ruminants

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Distinct roles of MicroRNAs in epithelium and mesenchyme during tooth development

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Signaling in Tooth, Hair, and Mammary Placodes

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Mesenchymal TGF-βSignaling Orchestrates Dental Epithelial Stem Cell Homeostasis Through Wnt Signaling

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Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years

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β-catenin Initiates Tooth Neogenesis in Adult Rodent Incisors

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Lineage tracing of epithelial cells in developing teeth reveals two strategies for building signaling centers

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Core Binding Factor Beta Functions in the Maintenance of Stem Cells and Orchestrates Continuous Proliferation and Differentiation in Mouse Incisors

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Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor

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Differential tissue growth and cell adhesion alone drive early tooth morphogenesis: An ex vivo and in silico study

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BMP Signaling in Regulating Mesenchymal Stem Cells in Incisor Homeostasis

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BCL11B Regulates Epithelial Proliferation and Asymmetric Development of the Mouse Mandibular Incisor

Kyrylkova, K., Kyryachenko, S., Biehs, B., Klein, O. D., Kioussi, C., & Leid, M. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037670 · Cited by 33

Molecular mediators of pulp inflammation and regeneration

Cooper, P. R., & Smith, A. J. (2013) · Endodontic Topics · doi:10.1111/etp.12036 · Cited by 32

Tissue Mechanical Forces and Evolutionary Developmental Changes Act Through Space and Time to Shape Tooth Morphology and Function

Calamari, Z. T., Hu, J. K., & Klein, O. D. (2018) · BioEssays · doi:10.1002/bies.201800140 · Cited by 32

Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency

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