The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index; none of the 143 sources its claims cite is checked for support yet.
Anxiety and Depression in COPD
Open accessAbstract
Background Approximately 60 million people in the United States live with one of four chronic conditions: heart disease, diabetes, chronic respiratory disease, and major depression. Anxiety and depression are very common comorbidities in COPD and have significant impact on patients, their families, society, and the course of the disease.Methods We report the proceedings of a multidisciplinary workshop on anxiety and depression in COPD that aimed to shed light on the current understanding of these comorbidities, and outline unanswered questions and areas of future research needs.Results Estimates of prevalence of anxiety and depression in COPD vary widely but are generally higher than those reported in some other advanced chronic diseases. Untreated and undetected anxiety and depressive symptoms may increase physical disability, morbidity, and health-care utilization. Several patient, physician, and system barriers contribute to the underdiagnosis of these disorders in patients with COPD. While few published studies demonstrate that these disorders associated with COPD respond well to appropriate pharmacologic and nonpharmacologic therapy, only a small proportion of COPD patients with these disorders receive effective treatment.Conclusion Future research is needed to address the impact, early detection, and management of anxiety and depression in COPD.
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In the paper
“Estimates of prevalence of anxiety and depression in COPD vary widely but are generally higher than those reported in some other advanced chronic diseases.”
§ Anxiety and Depression in COPD* > Abstract > Results
What the sources say
- Not checked yetcites [32] Solano, 2006, A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease, J Pain Symptom Manage source
Strength:hedged· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIn the paper
“Anxiety and depression often appear together in patients with COPD.6”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“In stable COPD, the prevalence of clinical depression ranges between 10% and 42%, while that of anxiety ranges between 10% and 19% (Table 2).6–25”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
- Not checked yetcites [7] van Manen, 2002, Risk of depression in patients with chronic obstructive pulmonary disease and its determinants, Thorax source
- Not checked yetcites [8] Wagena, 2004, Risk of depression and anxiety in employees with chronic bronchitis: the modifying effect of cigarette smoking, Psychosom Med source
- Not checked yetcites [9] Kunik, 2001, One session cognitive behavioural therapy for elderly patients with chronic obstructive pulmonary disease, Psychol Med source
- Not checked yetcites [10] Mikkelsen, 2004, Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD): a review, Nord J Psychiatry source
- Not checked yetcites [11] Aydin, 2001, Depression, anxiety comorbidity, and disability in tuberculosis and chronic obstructive pulmonary disease patients: applicability of GHQ-12, Gen Hosp Psychiatry source
- Not checked yetcites [12] Yohannes, 2000, Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence, and validation of the BASDEC screening questionnaire, Int J Geriatr Psychiatry source
- Not checked yetcites [13] Lacasse, 2001, Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent chronic obstructive pulmonary disease, J Cardiopulm Rehabil source
- Not checked yetcites [14] Aghanwa, 2001, Specific psychiatric morbidity among patients with chronic obstructive pulmonary disease in a Nigerian general hospital, J Psychosom Res source
- Not checked yetcites [15] McSweeny, 1982, Life quality of patients with chronic obstructive pulmonary disease, Arch Intern Med source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“In stable COPD, the prevalence of clinical depression ranges between 10% and 42%, while that of anxiety ranges between 10% and 19% (Table 2).6–25”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
- Not checked yetcites [7] van Manen, 2002, Risk of depression in patients with chronic obstructive pulmonary disease and its determinants, Thorax source
- Not checked yetcites [8] Wagena, 2004, Risk of depression and anxiety in employees with chronic bronchitis: the modifying effect of cigarette smoking, Psychosom Med source
- Not checked yetcites [9] Kunik, 2001, One session cognitive behavioural therapy for elderly patients with chronic obstructive pulmonary disease, Psychol Med source
- Not checked yetcites [10] Mikkelsen, 2004, Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD): a review, Nord J Psychiatry source
- Not checked yetcites [11] Aydin, 2001, Depression, anxiety comorbidity, and disability in tuberculosis and chronic obstructive pulmonary disease patients: applicability of GHQ-12, Gen Hosp Psychiatry source
- Not checked yetcites [12] Yohannes, 2000, Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence, and validation of the BASDEC screening questionnaire, Int J Geriatr Psychiatry source
- Not checked yetcites [13] Lacasse, 2001, Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent chronic obstructive pulmonary disease, J Cardiopulm Rehabil source
- Not checked yetcites [14] Aghanwa, 2001, Specific psychiatric morbidity among patients with chronic obstructive pulmonary disease in a Nigerian general hospital, J Psychosom Res source
- Not checked yetcites [15] McSweeny, 1982, Life quality of patients with chronic obstructive pulmonary disease, Arch Intern Med source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“only a small proportion of COPD patients with these disorders receive effective treatment.”
§ Anxiety and Depression in COPD* > Abstract > Results
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
- Not checked yetcites [33] Kim, 2000, Functional impairment in COPD patients: the impact of anxiety and depression, Psychosomatics source
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesNone of the sources cited for this claim have been checked yet.
In the paper
“Untreated and undetected anxiety and depressive symptoms may increase physical disability, morbidity, and health-care utilization.”
§ Anxiety and Depression in COPD* > Abstract > Results
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
- Not checked yetcites [22] Bosley, 1996, Psychological factors associated with use of home nebulized therapy for COPD, Eur Respir J source
- Not checked yetcites [26] Gudmundsson, 2006, Depression, anxiety and health status after hospitalisation for COPD: a multicentre study in the Nordic countries, Respir Med source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIn the paper
“Several patient, physician, and system barriers contribute to the underdiagnosis of these disorders in patients with COPD.”
§ Anxiety and Depression in COPD* > Abstract > Results
What the sources say
- Not checked yetcites [74] Katon, 2001, Rethinking practitioner roles in chronic illness: the specialist, primary care physician, and the practice nurse, Gen Hosp Psychiatry source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesThe paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Estimates of prevalence of anxiety and depression in COPD vary widely but are generally higher than those reported in some other advanced chronic diseases.”
§ Anxiety and Depression in COPD* > Abstract > Results
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesThe paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Prevalence estimates vary widely, due in part to the use of varied measurement tools and to the different degrees of illness severity across studies.”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
Strength:plain· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIn the paper
“with the highest rates, up to 62%, found in oxygen-dependent patients.13”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [13] Lacasse, 2001, Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent chronic obstructive pulmonary disease, J Cardiopulm Rehabil source
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
- Probably not a substantial claim. 13
- It may state two separate claims as one. 23
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Anxiety and depression are very common comorbidities in COPD and have significant impact on patients, their families, society, and the course of the disease.”
§ Anxiety and Depression in COPD* > Abstract > Background
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✗ Based: failsProbably not a substantial claim. The paper may give no reason why it holds.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Anxiety and depression are very common comorbidities in COPD and have significant impact on patients, their families, society, and the course of the disease.”
§ Anxiety and Depression in COPD* > Abstract > Background
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✗ Based: failsProbably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“Untreated or incompletely treated depression and anxiety have major implications for compliance with medical treatment, increased frequency of hospital admissions, prolonged length of stay, and increased consultations with primary care physicians.6,22,26”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [6] Kunik, 2005, Surprisingly high prevalence of anxiety and depression in chronic breathing disorders, Chest
- Not checked yetcites [22] Bosley, 1996, Psychological factors associated with use of home nebulized therapy for COPD, Eur Respir J source
- Not checked yetcites [26] Gudmundsson, 2006, Depression, anxiety and health status after hospitalisation for COPD: a multicentre study in the Nordic countries, Respir Med source
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
In the paper
“Gilbody et al85 reported in a systematic review of 37 randomized trials of collaborative care vs usual primary care that a collaborative-care model was associated with a twofold increase in adherence to antidepressant medication over a 6-month period as well as significant improvement in depressive symptoms for 2 to 5 years.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > The Collaborative-Care Model in COPD
What the sources say
- Not checked yetcites [85] Gilbody, 2006, Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes, Arch Intern Med source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“This study87 showed that the nurse collaborative-care intervention was associated with significant improvements in quality of depression care, depressive outcomes, and physical functioning compared to usual care over a 2-year period.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > The Collaborative-Care Model in COPD
What the sources say
- Not checked yetcites [87] Unutzer, 2002, Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial, JAMA source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“While most primary care physicians inquire about and record smoking status, few assess symptoms associated with smoking that may lead to a suspicion of COPD, such as chronic productive cough, dyspnea with exertion, or change in functional status due to breathing difficulties.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > The Primary Care Perspective
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✗ Based: failsProbably not a substantial claim. The paper may give no reason why it holds.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The PHQ-9 nine-question screener can be scored and is useful for diagnosis and follow-up.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Summary
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✗ Based: failsProbably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Physician barriers include short clinical visit times, the lack of close follow-up, the lack of time for educating patients about depression and counseling, limited skills, and knowledge of mood disorders.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Barriers to the Detection and Management of Anxiety and Depression in COPD
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In this setting, it may be the identification of COPD that is most crucial to improving care of depression in patients with COPD.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > The Primary Care Perspective
Tests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“System issues include the lack of electronic records and registries, poor communication between primary care and mental health care, emphasis on productivity measured as patient throughput, and absence of reimbursement.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Barriers to the Detection and Management of Anxiety and Depression in COPD
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
In the paper
“Only one half of patients with major depression receive an accurate diagnosis in primary care and, of those with a diagnosis of major depression, only one third to one half receive appropriate pharmacotherapy or psychotherapy.84”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > The Collaborative-Care Model in COPD
What the sources say
- Not checked yetcites [84] Simon, 2002, Evidence review: efficacy and effectiveness of antidepressant treatment in primary care, Gen Hosp Psychiatry source
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“Other barriers may include preference for depression care within the primary care system, and therapies that may be limited by insurance coverage or accessibility.74”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Barriers to the Detection and Management of Anxiety and Depression in COPD
What the sources say
- Not checked yetcites [74] Katon, 2001, Rethinking practitioner roles in chronic illness: the specialist, primary care physician, and the practice nurse, Gen Hosp Psychiatry source
Strength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Probably the most commonly used tool in primary care for depression screening is the PHQ-9 (www.predictonline.com/phq9.htm).”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > The Primary Care Perspective
Strength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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In the paper
“Less commonly used choices include the Zung Self-Rating Depression Scale and the CES-D.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Summary
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“The Patient Health Questionnaire-9 (PHQ-9) is a nine-item measure that emulates the DSM-IV and is useful for making a diagnosis of depression and monitoring response to treatment.67”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Screening for Anxiety and Depression
What the sources say
- Not checked yetcites [67] Kroenke, 2001, The PHQ-9: validity of a brief depression severity measure, J Gen Intern Med source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Frequent panic attacks in COPD patients who are receiving medications as prescribed are most often related to a concurrent depressive syndrome, and treatment should be directed to both depressive and anxiety components.52”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Efficacy of Different Treatment Models in COPD
What the sources say
- Not checked yetcites [52] Borson, 1998, Depression and chronic obstructive pulmonary disease: treatment trials, Semin Clin Neuropsychiatry
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Moving these models into everyday practice requires overcoming both clinical and system barriers.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > COPD Mood/Anxiety Disorder Screening: Implications for Public Policy
Strength:plain· not yet calibratedTests✓ Asserted: passes✗ Checkable: fails✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“A variety of validated, easily administered, or self-administered depression screening tools are available.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Summary
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✗ Based: failsProbably not a substantial claim. The paper may give no reason why it holds.
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In the paper
“Several tools, including the Patient Health Questionnaire-3, a three-question screener, and the HADS, are available but are not as well validated as the depression screening tools.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Summary
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✗ Based: failsProbably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
In the paper
“In recent years, a model of care termed the collaborative-care model has been found to be associated with marked improvements in the quality of depression care in primary care and significant improvement in depression outcomes.74”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > The Collaborative-Care Model in COPD
What the sources say
- Not checked yetcites [74] Katon, 2001, Rethinking practitioner roles in chronic illness: the specialist, primary care physician, and the practice nurse, Gen Hosp Psychiatry source
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“In addition, depression lowers quality of life and decreases adherence to treatment.22,58”
§ Anxiety and Depression in COPD* > THE SCOPE OF THE PROBLEM > Prevalence and Impact of Anxiety and Depression in COPD
What the sources say
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
In the paper
“In another study83 that compared CBT with COPD education in patients with anxiety and depressive symptoms, both treatments had a significant effect in improving quality of life and decreasing anxiety and depression (p < 0.005) over 8 weeks. These improvements were maintained during follow-up.83”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Efficacy of Different Treatment Models in COPD
What the sources say
- Not checked yetcites [83] Kunik, 2007, COPD education and cognitive behavioral therapy group treatment for clinically significant symptoms of depression and anxiety in COPD patients: a randomized controlled trial, Psychol Med
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Psychological approaches to care have not been adequately developed or studied in clinically depressed COPD patients.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Efficacy of Different Treatment Models in COPD
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✗ Based: failsProbably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
In the paper
“A second small randomized placebo-controlled trial80 using citalopram (a selective serotonin reuptake inhibitor [SSRI] antidepressant) in lung transplant patients with self-rated depressive symptoms, rather than major depression, found no overall benefit, with small improvements seen only in the less severely affected patients.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Efficacy of Different Treatment Models in COPD
What the sources say
- Not checked yetcites [80] Silvertooth, 2004, Citalopram and quality of life in lung transplant recipients, Psychosomatics source
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Many of the somatic symptoms of a major depression overlap with symptoms caused by severe COPD, although sustained depressed mood and marked loss of pleasure in life should not be attributed to lung disease alone.”
§ Anxiety and Depression in COPD* > DETECTING MOOD/ANXIETY DISORDERS IN THE COPD POPULATION > Screening for Anxiety and Depression
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, while there is strong evidence that suggests PR improves exercise capacity and quality of life, the evidence for its impact on clinical anxiety and depression is less defined.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
Load-bearingStrength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“Symptoms of anxiety may be reflected in a variety of ways, including agitation as well as physiologic signs of arousal such as tachycardia, sweating, and dyspnea.93”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
What the sources say
- Not checked yetcites [93] Hynninen, 2005, Psychological characteristics of patients with chronic obstructive pulmonary disease: a review, J Psychosom Res source
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Patients with chronic conditions can take responsibility for the day-to-day management of their condition, with the result of improving their confidence, control, and autonomy.99”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
What the sources say
- Not checked yetcites [99] Lorig, 1999, Evidence suggesting that a chronic disease self-management program can improve health status while reducing hospitalization: a randomized trial, Med Care source
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“It does improve depressive symptoms, but its effect beyond the duration of the rehabilitation program remains to be defined.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Summary
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“Griffiths and colleagues97 reported reduced symptoms of anxiety and depression following a 6-week PR program, with symptoms of depression remaining significantly reduced at 12-month follow-up.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
What the sources say
- Not checked yetcites [97] Griffiths, 2000, Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial, Lancet source
Strength:plain· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
In the paper
“A study by de Godoy and de Godoy103 reported reductions in depression and anxiety only among patients who participated in education and stress management in addition to exercise training during a 12-week intervention. They found that exercise training alone did not appear to have a beneficial effect on symptoms of depression and anxiety.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
What the sources say
- Not checked yetcites [103] de Godoy, 2003, A randomized controlled trial of the effect of psychotherapy on anxiety and depression in chronic obstructive pulmonary disease, Arch Phys Med Rehabil source
Strength:hedged· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Brief CBT will help decrease the sensation of dyspnea as well as symptoms of anxiety and depression.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Efficacy of Different Treatment Models in COPD
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
In the paper
“History of treatment for depression was associated with limited change in depressive symptoms, whereas social support and satisfaction with treatment were predictors of improvement.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > PR: an Example of a Collaborative-Care Model
What the sources say
- Not checked yetcites [104] Alexopoulos, 2006, Outcomes of depressed patients undergoing inpatient pulmonary rehabilitation, Am J Geriatr Psychiatry source
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Patients with major depressive disorder are less likely to respond. They require specialized care from a mental health professional.”
§ Anxiety and Depression in COPD* > MANAGEMENT OF ANXIETY AND DEPRESSION IN COPD > Summary
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
The authors state this as an assumption.
The prevalence of minor or subclinical depression in COPD is similar to that in other chronic illnesses.
“However, the prevalence of minor or subclinical depression may be even higher in this population, assuming that it is similar to other chronic illnesses.”
The paper relies on this without support.
Depression can be managed effectively using a chronic care model in primary care settings.
“Depression can be managed effectively using a chronic care model in the primary care settings.”
The paper relies on this without support.
Patients with comorbid depression and general medical illness are more impaired, have higher mortality, and have 50 to 100% higher medical costs than those without depression, even after controlling for demographics and severity of medical illness.
“Patients with comorbid depression and general medical illness are more impaired, have higher mortality, and have 50 to 100% higher medical costs than those without depression, even after controlling for demographics and severity of medical illness.”
The paper relies on this without support.
Many COPD patients have transitory mood symptoms during respiratory exacerbations that improve spontaneously as their physical status improves.
“Many COPD patients have transitory mood symptoms during respiratory exacerbations that improve spontaneously as their physical status improves.”
The paper relies on this without support.
Anxiety and panic attacks are often associated with acute respiratory exacerbations but may also be associated with the pharmacologic effects of β2-agonists or high-dose corticosteroid therapy.
“Anxiety and panic attacks are often associated with acute respiratory exacerbations but may also be associated with the pharmacologic effects of β2-agonists or high-dose corticosteroid therapy.”
The paper relies on this without support.
In stable patients with severe COPD and marginal physiologic reserve, small amounts of exercise can precipitate panic attacks due to severe dyspnea sometimes accompanied by hypoxemia.
“In stable patients with severe COPD and marginal physiologic reserve, small amounts of exercise can precipitate panic attacks due to severe dyspnea sometimes accompanied by hypoxemia.”
The authors state this as an assumption.
CBT is based on the assumption that individuals with emotional distress tend to interpret their life experiences in a distorted way.
“CBT is based on the assumption that individuals with emotional distress tend to interpret their life experiences in a distorted way.”
The paper relies on this without support.
Symptoms consistent with anxiety or depression are highly prevalent among patients enrolling in PR.
“The high prevalence of symptoms consistent with anxiety or depression among those enrolling in PR”
The paper relies on this without support.
Dyspnea is a symptom of both COPD and anxiety.
“Dyspnea is a symptom of both COPD and anxiety”
The paper relies on this without support.
Symptoms of anxiety may contribute to the patient’s reluctance to engage in exercise as well as to difficulty concentrating.
“Symptoms of anxiety may contribute to the patient’s reluctance to engage in exercise as well as to difficulty concentrating.”
The paper relies on this without support.
SSRIs have been safely used in other chronic illnesses.
“SSRIs have been safely used in other chronic illnesses.”
The paper relies on this without support.
Tricyclic antidepressants are effective treatments for depression, anxiety, or insomnia.
“Tricyclic antidepressants are effective treatments for depression, anxiety, or insomnia”
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The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“whereas that of anxiety varieties between 10% and 19% [11].”
From A psychological intervention to promote acceptance and adherence to non-invasive ventilation in people with chronic obstructive pulmonary disease: study protocol of a randomised controlled trial. (2017) · cites this paper as [11]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Evidence suggests that there is an increased prevalence of anxiety disorders in people with COPD (Maurer 2008).”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Maurer 2008
The cited source says what the claim attributes to it.
In the citing paper
“Despite assumptions to the contrary from previous research11,16,30, an important and unique finding in this study was that respiratory clinicians recognised the complex mental health needs of people with COPD, and proactively attempted to manage psychological issues.”
From The complexity of mental health care for people with COPD: a qualitative study of clinicians’ perspectives (2021) · cites this paper as [16]
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Metadata
- Authors
- Maurer, J., Rebbapragada, V., Borson, S., Goldstein, R., Kunik, M. E., Yohannes, A. M., & Hanania, N. A.
- Affiliations
- Baylor College of Medicine (US)
- University of Toronto (CA)
- Michael E. DeBakey VA Medical Center (US)
- Manchester Metropolitan University (GB)
- Corresponding author
- Hanania, Nicola A.
- Venue
- Chest
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 134
- Issue
- 4
- Pages
- 43S-56S
- ISSN
- 0012-3692 (ISSN-L)
- PMC
- PMC2849676
- OpenAlex
- W2161243447
- Cited by
- 720
- References
- 113
- Citations by year
- 2026: 16 · 2025: 34 · 2024: 34 · 2023: 33 · 2022: 32 · 2021: 41 · 2020: 39 · 2019: 33 · 2018: 50 · 2017: 50 · 2016: 61 · 2015: 43 · 2014: 48 · 2013: 57 · 2012: 43
- FWCI
- 5.59
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- CHEST Journal (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (P50AG005136)
- National Institute of Mental Health (R13MH073228)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Keywords
- chronic obstructive pulmonary disease, anxiety, depression, comorbidities, prevalence, underdiagnosis, barriers to treatment, pharmacotherapy, non-pharmacological treatment, physical disability, health care utilization
- MeSH terms
- Antidepressive Agents, Anxiety, Depression, Humans, Prognosis, Anti-Anxiety Agents, United States, Cognitive Behavioral Therapy, Incidence, Prevalence, Pulmonary Disease, Chronic Obstructive, Biomedical Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
A language model drew the claims from the paper on 2026-10-11, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).
A second model labelled each claim on 2026-10-11 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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