Anxiolytic drug discovery: What are the novel approaches and how can we improve them?

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

Gottesman, I. I., & Gould, T. D. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.4.636 · Cited by 5,615 · see citing works

Antidepressant effects of ketamine in depressed patients

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00230-9 · Cited by 3,856 · see citing works

Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish

Egan, R. J., Bergner, C., Hart, P. C., Cachat, J., Canavello, P. R., Elegante, M. F., Elkhayat, S. I., Bartels, B. K., Tien, A. K., Tien, D. H., et al. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.06.022 · Cited by 1,381 · see citing works

Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease

Benabid, A. L., Chabardes, S., Mitrofanis, J., & Pollak, P. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70291-6 · Cited by 1,285 · see citing works

Hallucinogens

Nichols, D. E. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2003.11.002 · Cited by 1,211 · see citing works

The ascent of mouse: advances in modelling human depression and anxiety

Cryan, J. F., & Holmes, A. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1825 · Cited by 1,198 · see citing works

Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up.

Rodríguez-Oroz, M., Obeso, J., Lang, A., Houeto, J., Pollak, P., Rehncrona, S., Kulisevsky, J., Albanese, A., Volkmann, J., Hariz, M., et al. (2005) · Brain : a journal of neurology · doi:10.1093/brain/awh571 · Cited by 1,120 · see citing works

Deep Brain Stimulation to Reward Circuitry Alleviates Anhedonia in Refractory Major Depression

Schlaepfer, T. E., Cohen, M. X., Frick, C., Kosel, M., Brodesser, D., Axmacher, N., Joe, A. Y., Kreft, M., Lenartz, D., & Sturm, V. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301408 · Cited by 1,027 · see citing works

Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic

Ressler, K. J., & Mayberg, H. S. (2007) · Nature Neuroscience · doi:10.1038/nn1944 · Cited by 1,007 · see citing works

Hallucinogens Recruit Specific Cortical 5-HT2A Receptor-Mediated Signaling Pathways to Affect Behavior

González-Maeso, J., Weisstaub, N. V., Zhou, M., Chan, P., Ivic, L., Ang, R., Lira, A., Bradley-Moore, M., Ge, Y., Zhou, Q., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.01.008 · Cited by 925 · see citing works

Psychological treatments for chronic post-traumatic stress disorder: Systematic review and meta-analysis

Bisson, J. I., Ehlers, A., Matthews, R., Pilling, S., Richards, D., & Turner, S. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.021402 · Cited by 900 · see citing works

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

Xu, B., Goulding, E. H., Zang, K., Cepoi, D., Cone, R. D., Jones, K. R., Tecott, L. H., & Reichardt, L. F. (2003) · Nature Neuroscience · doi:10.1038/nn1073 · Cited by 896 · see citing works

Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression

Bewernick, B. H., Hurlemann, R., Matusch, A., Kayser, S., Grubert, C., Hadrysiewicz, B., Axmacher, N., Lemke, M., Cooper-Mahkorn, D., Cohen, M. X., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.013 · Cited by 865 · see citing works

Three-Year Outcomes in Deep Brain Stimulation for Highly Resistant Obsessive–Compulsive Disorder

Greenberg, B. D., Malone, D. A., Friehs, G. M., Rezai, A. R., Kubu, C. S., Malloy, P. F., Salloway, S., Okun, M. S., Goodman, W. K., & Rasmussen, S. A. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301165 · Cited by 831 · see citing works

BDNF regulates eating behavior and locomotor activity in mice

Kernie, S. G., Liebl, D. J., & Parada, L. F. (2000) · The EMBO Journal · doi:10.1093/emboj/19.6.1290 · Cited by 806 · see citing works

Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder

Moreno, F. A., Wiegand, C. B., Taitano, E. K., & Delgado, P. L. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n1110 · Cited by 789 · see citing works

The age of anxiety? The birth cohort change in anxiety and neuroticism, 1952-1993.

Twenge, J. M. (2000) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.79.6.1007 · Cited by 786 · see citing works

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

Rios, M., Fan, G., Fekete, C., Kelly, J., Bates, B., Kuehn, R., Lechan, R. M., & Jaenisch, R. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.10.0706 · Cited by 781 · see citing works

A review on cognitive impairments in depressive and anxiety disorders with a focus on young adults

Castaneda, A. E., Tuulio‐Henriksson, A., MARTTUNEN, M. J., Suvisaari, J., & Lönnqvist, J. K. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.06.006 · Cited by 755 · see citing works

Measuring behavioral and endocrine responses to novelty stress in adult zebrafish

Cachat, J., Stewart, A., Grossman, L., et al. (2010) · Nature Protocols · doi:10.1038/nprot.2010.140 · Cited by 698 · see citing works

Vagal nerve stimulation: a review of its applications and potential mechanisms that mediate its clinical effects

Groves, D. A., & Brown, V. J. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.01.004 · Cited by 677 · see citing works

The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study

Mithoefer, M. C., Wagner, M. T., Mithoefer, A. T., Jerome, L., & Doblin, R. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881110378371 · Cited by 674 · see citing works

Physiological substrates of mammalian monogamy: The prairie vole model

Sue Carter, C., Courtney Devries, A., & Getz, L. L. (1995) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)00070-h · Cited by 615 · see citing works

The Peptide That Binds: A Systematic Review of Oxytocin and its Prosocial Effects in Humans

MacDonald, K., & MacDonald, T. M. (2010) · Harvard Review of Psychiatry · doi:10.3109/10673220903523615 · Cited by 585 · see citing works

The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders

Sturm, V., Lenartz, D., Koulousakis, A., Treuer, H., Herholz, K., Klein, J. C., & Klosterkötter, J. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.09.003 · Cited by 567 · see citing works

A randomized, double-blind clinical trial on the efficacy of cortical direct current stimulation for the treatment of major depression

Boggio, P. S., Rigonatti, S. P., Ribeiro, R. B., Myczkowski, M. L., Nitsche, M. A., Pascual‐Leone, Á., & Fregni, F. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007833 · Cited by 566 · see citing works

Psychiatric endophenotypes and the development of valid animal models

Gould, T. D., & Gottesman, I. I. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00186.x · Cited by 507 · see citing works

Developmental programming of obesity in mammals

Taylor, P. D., & Poston, L. (2007) · Experimental Physiology · doi:10.1113/expphysiol.2005.032854 · Cited by 473 · see citing works

The comparative neuroanatomy and neurochemistry of zebrafish CNS systems of relevance to human neuropsychiatric diseases

Panula, P., Chen, Y.-C., Priyadarshini, M., Kudo, H., Semenova, S. A., Sundvik, M., & Sallinen, V. J. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.010 · Cited by 454 · see citing works

Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers

Vollenweider, F. X., Gamma, A., Liechti, M., & Huber, T. (1998) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00013-x · Cited by 448 · see citing works

Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP

Silverman, J. L., Tolu, S. S., Barkan, C. L., & Crawley, J. N. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.201 · Cited by 438 · see citing works

Development of the corticosteroid stress axis and receptor expression in zebrafish

Alsop, D. H., & Vijayan, M. M. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00671.2007 · Cited by 430 · see citing works

Serotonin research: contributions to understanding psychoses

GEYER, M., & VOLLENWEIDER, F. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.06.006 · Cited by 427 · see citing works

Comparative anatomy of the histaminergic and other aminergic systems in zebrafish ( Danio rerio )

Kaslin, J., & Panula, P. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1390 · Cited by 403 · see citing works

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Mirnics, K., Middleton, F. A., Lewis, D. A., & Levitt, P. R. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01862-2 · Cited by 393 · see citing works

Functional and developmental analysis of the blood–brain barrier in zebrafish

Jeong, J.-Y., Kwon, H.-B., Ahn, J.-C., Kang, D., Kwon, S., Park, J. A., & Kim, K.-W. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.10.043 · Cited by 391 · see citing works

Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodes

Nahas, Z., Marangell, L. B., Husain, M. M., Rush, A. J., Sackeim, H. A., Lisanby, S. H., Martinez, J. M., & George, M. S. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0902 · Cited by 390 · see citing works

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

Oka, T., Nishimura, Y., Zang, L., Hirano, M., Shimada, Y., Wang, Z., Umemoto, N., Kuroyanagi, J., Nishimura, N., & Tanaka, T. (2010) · BMC Physiology · doi:10.1186/1472-6793-10-21 · Cited by 386 · see citing works

Oxytocin, vasopressin and sociality

CARTER, C., GRIPPO, A., POURNAJAFINAZARLOO, H., RUSCIO, M., & PORGES, S. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00427-5 · Cited by 380 · see citing works

Deep brain stimulation in 18 patients with severe Gilles de la Tourette syndrome refractory to treatment: the surgery and stimulation

Servello, D., Porta, M., Sassi, M., Brambilla, A., & Robertson, M. M. (2007) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2006.104067 · Cited by 350 · see citing works

Effects of Schedule I drug laws on neuroscience research and treatment innovation

Nutt, D., King, L. A., & Nichols, D. E. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3530 · Cited by 338 · see citing works

Anxiety and stress responses in female oxytocin deficient mice

Amico, J. A., Mantella, R. C., Vollmer, R. R., & Li, X. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.0953-8194.2004.01161.x · Cited by 327 · see citing works

Psychedelics and the Human Receptorome

Ray, T. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009019 · Cited by 300 · see citing works

Modulatory Neurotransmitter Systems and Behavior: Towards Zebrafish Models of Neurodegenerative Diseases

Panula, P., Sallinen, V. J., Sundvik, M., Kolehmainen, J., Torkko, V., Tiittula, A., Moshnyakov, M., & Podlasz, P. (2006) · Zebrafish · doi:10.1089/zeb.2006.3.235 · Cited by 296 · see citing works

Regional induction of fos immunoreactivity in the brain by anticonvulsant stimulation of the vagus nerve

Naritoku, D. K., Terry, W. J., & Helfert, R. H. (1995) · Epilepsy Research · doi:10.1016/0920-1211(95)00035-9 · Cited by 291 · see citing works

What's wrong with my mouse model?

Kalueff, A. V., Wheaton, M., & Murphy, D. L. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.01.023 · Cited by 285 · see citing works

Prosocial effects of oxytocin and clinical evidence for its therapeutic potential

Striepens, N., Kendrick, K. M., Maier, W., & Hurlemann, R. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.001 · Cited by 283 · see citing works

Zebrafish: A Complete Animal Model for In Vivo Drug Discovery and Development

Chakraborty, C., Hsu, C., Wen, Z. H., Lin, C., & Agoramoorthy, G. (2009) · Current Drug Metabolism · doi:10.2174/138920009787522197 · Cited by 279 · see citing works

Approaching the shared biology of obesity and depression: the stress axis as the locus of gene–environment interactions

Bornstein, S. R., Schuppenies, A., Wong, M., & Licinio, J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001873 · Cited by 267 · see citing works

Synaptic Mechanisms Underlying Rapid Antidepressant Action of Ketamine

Kavalali, E. T., & Monteggia, L. M. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12040531 · Cited by 258 · see citing works

Developmental Origins of Obesity and the Metabolic Syndrome: The Role of Maternal Obesity

Armitage, J. A., Poston, L., & Taylor, P. D. (2008) · KARGER eBooks · doi:10.1159/000115355 · Cited by 255 · see citing works

A review of functional neuroimaging studies of vagus nerve stimulation (VNS)

Chae, J.-H., Nahas, Z., Lomarev, M., Denslow, S., Lorberbaum, J. P., Bohning, D. E., & George, M. S. (2003) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(03)00074-8 · Cited by 255 · see citing works

A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders

George, M. S., Ward, H. E., Ninan, P. T., Pollack, M., Nahas, Z., Anderson, B., Kose, S., Howland, R. H., Goodman, W. K., & Ballenger, J. C. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.02.001 · Cited by 251 · see citing works

Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish

Richetti, S. K., Blank, M., Capiotti, K. M., Piato, Â., Bogo, M. R., Vianna, M. R. M. R., & Bonan, C. D. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.09.027 · Cited by 248 · see citing works

Characterization of behavioral and endocrine effects of LSD on zebrafish

Grossman, L., Utterback, E., Stewart, A., Gaikwad, S., Chung, K. M., Suciu, C., Wong, K., Elegante, M. F., Elkhayat, S. I., Tan, J., et al. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.05.039 · Cited by 247 · see citing works

Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models

Stewart, A., Wu, N., Cachat, J., Hart, P. C., Gaikwad, S., Wong, K., Utterback, E., Gilder, T., Kyzar, E. J., Newman, A., et al. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.11.035 · Cited by 240 · see citing works

Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation

Grippo, A. J., Trahanas, D. M., Zimmerman, R. R., Porges, S. W., & Carter, C. S. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.05.017 · Cited by 240 · see citing works

Identification of the Zebrafish Ventral Habenula As a Homolog of the Mammalian Lateral Habenula

Amo, R., Aizawa, H., Takahoko, M., Kobayashi, M. S., Takahashi, R., Aoki, T., & Okamoto, H. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3690-09.2010 · Cited by 236 · see citing works

Obesity and psychiatric disorders: Commonalities in dysregulated biological pathways and their implications for treatment

Lopresti, A. L., & Drummond, P. D. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.05.005 · Cited by 231 · see citing works

The behavioral pharmacology of hallucinogens

Fantegrossi, W. E., Murnane, K. S., & Reissig, C. J. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.018 · Cited by 226 · see citing works

The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies

Modi, M. E., & Young, L. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.010 · Cited by 218 · see citing works

Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution

Gorissen, M., Bernier, N. J., Nabuurs, S. B., Flik, G., & Huising, M. O. (2009) · Journal of Endocrinology · doi:10.1677/joe-09-0034 · Cited by 213 · see citing works

Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models

Li, M.-L., Sloboda, D., & Vickers, M. (2011) · International Journal of Experimental Diabetes Research · doi:10.1155/2011/592408 · Cited by 211 · see citing works

Identification of a brain center whose activity discriminates a choice behavior in zebrafish

Lau, B. Y. B., Mathur, P., Gould, G. G., & Guo, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018275108 · Cited by 199 · see citing works

Zebrafish in Endocrine Systems: Recent Advances and Implications for Human Disease

Löhr, H., & Hammerschmidt, M. (2011) · Annual Review of Physiology · doi:10.1146/annurev-physiol-012110-142320 · Cited by 199 · see citing works

Depression-like behavior and stressor-induced neuroendocrine activation in female prairie voles exposed to chronic social isolation

Grippo, A. J., Cushing, B. S., & Carter, C. S. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31802f054b · Cited by 196 · see citing works

Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats

Slattery, D. A., & Neumann, I. D. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.038 · Cited by 195 · see citing works

Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood

Sasaki, A., de Vega, W. C., St-Cyr, S., Pan, P., & McGowan, P. O. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.02.044 · Cited by 194 · see citing works

Social isolation disrupts autonomic regulation of the heart and influences negative affective behaviors

Grippo, A. J., Lamb, D. G., Carter, C. S., & Porges, S. W. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.04.011 · Cited by 188 · see citing works

Blood—Brain Barrier and Peptides

Ermisch, A., Rühle, H., Landgraf, R., & Hess, J. (1985) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1985.49 · Cited by 187 · see citing works

Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders

MacDonald, K., & Feifel, D. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00035 · Cited by 181 · see citing works

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models

Andrus, B. M., Blizinsky, K., Vedell, P. T., Dennis, K., Shukla, P. K., Schaffer, D. J., Radulovic, J., Churchill, G. A., & Redei, E. E. (2012) · Molecular Psychiatry · doi:10.1038/mp.2010.119 · Cited by 178 · see citing works

Behavioral and physiological effects of acute ketamine exposure in adult zebrafish

Riehl, R., Kyzar, E. J., Allain, A. V., Green, J. B. A., Hook, M., Monnig, L., Rhymes, K., Roth, A., Pham, M., Razavi, R., et al. (2011) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2011.05.011 · Cited by 163 · see citing works

Validating ‘hard’ and ‘soft’ phenotypes within the bipolar spectrum: continuity or discontinuity?

Akiskal, H. S. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00390-7 · Cited by 162 · see citing works

Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users: the longitudinal perspective

Thomasius, R., Zapletalova, P., Petersen, K. U., Buchert, R., Andresen, B., Wartberg, L., Nebeling, B., & Schmoldt, A. (2006) · Journal of Psychopharmacology · doi:10.1177/0269881106059486 · Cited by 158 · see citing works

Animal Models of Serotonergic Psychedelics

Hanks, J. B., & González-Maeso, J. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn300138m · Cited by 156 · see citing works

Cognitive bias in the chick anxiety–depression model

Salmeto, A. L., Hymel, K. A., Carpenter, E. C., Brilot, B., Melissa Bateson, B., & Sufka, K. J. (2010) · Brain Research · doi:10.1016/j.brainres.2010.12.007 · Cited by 155 · see citing works

Differential Clearance of Neurophysin and Neurohypophysial Peptides from the Cerebrospinal Fluid in Conscious Guinea Pigs

Jones, P. M., & Robinson, I. C. A. F. (2008) · Neuroendocrinology · doi:10.1159/000123316 · Cited by 148 · see citing works

Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism

Silverman, J. L., Yang, M., Turner, S. M., Katz, A. M., Bell, D. B., Koenig, J. I., & Crawley, J. N. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.059 · Cited by 146 · see citing works

Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist

Ring, R. H., Schechter, L. E., Leonard, S. K., Dwyer, J. M., Platt, B. J., Graf, R., Grauer, S. M., Pulicicchio, C. M., Resnick, L., Rahman, Z. U., et al. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.07.016 · Cited by 144 · see citing works

Clozapine produces potent antidopaminergic effects anatomically specific to the mesolimbic system.

Pigott, T. A., L'Heureux, F., Dubbert, B., Bernstein, S., & Murphy, D. L. (1994) · PubMed · Cited by 143 · see citing works

Zebrafish models to study drug abuse-related phenotypes

Stewart, A., Wong, K., Jonathan Cachat, P., Gaikwad, S., Kyzar, E., Wu, N., Hart, P., Piet, V., Utterback, E., Elegante, M., et al. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.011 · Cited by 141 · see citing works

Peripheral Pulses of Oxytocin Increase Partner Preferences in Female, but Not Male, Prairie Voles

Cushing, B. S., & Carter, C. S. (2000) · Hormones and Behavior · doi:10.1006/hbeh.1999.1558 · Cited by 136 · see citing works

Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders

Murphy, D. L., Uhl, G. R., Holmes, A., Ren‐Patterson, R. F., Hall, F. S., Sora, I., Detera‐Wadleigh, S. D., & Lesch, K. (2003) · Genes Brain & Behavior · doi:10.1046/j.1601-1848.2003.00049.x · Cited by 129 · see citing works

Neural melanocortin receptors in obesity and related metabolic disorders

Girardet, C., & Butler, A. A. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.05.004 · Cited by 128 · see citing works

Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment

Wong, R. Y., Oxendine, S. E., & Godwin, J. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-348 · Cited by 128 · see citing works

Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders

Stamou, M., Streifel, K. M., Goines, P. E., & Lein, P. J. (2013) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2012.12.001 · Cited by 128 · see citing works

Zebrafish Neurobehavioral Protocols

(2010) · Neuromethods · doi:10.1007/978-1-60761-953-6 · Cited by 127 · see citing works

Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders

Kim, S., & Webster, M. J. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.99 · Cited by 127 · see citing works

Feasibility of Vagus Nerve Stimulation–Synchronized Blood Oxygenation Level–Dependent Functional MRI

Bohning, D. E., Lomarev, M. P., Denslow, S., Nahas, Z. H., Shastri, A., & George, M. S. (2001) · Investigative Radiology · doi:10.1097/00004424-200108000-00006 · Cited by 127 · see citing works

Loss of brain‐derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice

Ren‐Patterson, R. F., Cochran, L. W., Holmes, A., Sherrill, S., Huang, S., Tolliver, T. J., Lesch, K., Lu, B., & Murphy, D. L. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20410 · Cited by 126 · see citing works

Animal models of programming: early life influences on appetite and feeding behaviour

Langley‐Evans, S. C., Bellinger, L., & McMullen, S. (2005) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2005.00015.x · Cited by 126 · see citing works

Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men

Kas, M. J. H., Fernandes, C., Schalkwyk, L. C., & Collier, D. A. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001979 · Cited by 122 · see citing works

Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology

Kyzar, E. J., Collins, C. J., Gaikwad, S., Green, J. B. A., Roth, A., Monnig, L., El-Ounsi, M., Davis, A., Freeman, A., Capezio, N., et al. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.01.003 · Cited by 120 · see citing works

Toward an integrative model of the spectrum of mood, behavioral and personality disorders based on fear and anger traits: I. Clinical implications

Lara, D. R., Pinto, O., Akiskal, K. K., & Akiskal, H. H. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.02.025 · Cited by 119 · see citing works

Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats

Furmaga, H., Shah, A., & Frazer, A. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.07.020 · Cited by 116 · see citing works

Stimulatory effect of intracerebroventricular administration of orexin A on food intake in the zebrafish, Danio rerio

Yokobori, E., Kojima, K., Azuma, M., Kang, K. S., Maejima, S., Uchiyama, M., & Matsuda, K. (2011) · Peptides · doi:10.1016/j.peptides.2011.05.010 · Cited by 110 · see citing works

Unique and potent effects of acute ibogaine on zebrafish: The developing utility of novel aquatic models for hallucinogenic drug research

Cachat, J., Kyzar, E. J., Collins, C. J., et al. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.08.041 · Cited by 110 · see citing works

Gene Expression Profiling with DNA Microarrays: Advancing Our Understanding of Psychiatric Disorders

Pongrac, J. L., Middleton, F. A., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2002) · Neurochemical Research · doi:10.1023/a:1020904821237 · Cited by 108 · see citing works

Fish melanocortin system

Cerdá‐Reverter, J. M., Agulleiro, M. J., Guillot, R., Sánchez, E., Ceinos, R. M., & Rotllant, J. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.10.108 · Cited by 105 · see citing works

Textbook of Anxiety Disorders

Zitman, F. G. (2011) · JAMA · doi:10.1001/jama.2011.151 · Cited by 105 · see citing works

A brief history of oxytocin and its role in modulating psychostimulant effects

Carson, D. S., Guastella, A. J., Taylor, E. R., & McGregor, I. S. (2013) · Journal of Psychopharmacology · doi:10.1177/0269881112473788 · Cited by 105 · see citing works

Zebrafish Model of the Blood-Brain Barrier: Morphological and Permeability Studies

Eliceiri, B. P., Gonzalez, A. M., & Baird, A. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-938-3_18 · Cited by 102 · see citing works

Longitudinal Relationship of Depressive and Anxiety Symptoms With Dyslipidemia and Abdominal Obesity

Dortland, A. K. B. V. R., Giltay, E. J., van Veen, T., Zitman, F. G., & Penninx, B. W. J. H. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318274d30f · Cited by 101 · see citing works

Striatal dopamine D2 receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings

Schneier, F. R., Martínez, D., Abi‐Dargham, A., Zea‐Ponce, Y., Simpson, H. B., Liebowitz, M. R., & Laruelle, M. A. (2007) · Depression and Anxiety · doi:10.1002/da.20268 · Cited by 100 · see citing works

Scopolamine-induced learning impairment reversed by physostigmine in zebrafish

Kim, Y., Lee, Y., Kim, D., Jung, M. W., & Lee, C. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.03.003 · Cited by 100 · see citing works

A Clinical Plan for MDMA (Ecstasy) in the Treatment of Posttraumatic Stress Disorder (PTSD): Partnering with the FDA

Doblin, R. (2002) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2002.10399952 · Cited by 99 · see citing works

Fishing for gene function – endocrine modelling in the zebrafish

McGonnell, I. M., & Fowkes, R. C. (2006) · Journal of Endocrinology · doi:10.1677/joe.1.06683 · Cited by 97 · see citing works

The Developing Utility of Zebrafish in Modeling Neurobehavioral Disorders

Stewart, A., Kadri, F., DiLeo, J., Chung, K. M., Cachat, J., Goodspeed, J. R., Suciu, C., Roy, S. S., Gaikwad, S., Wong, K., et al. (2010) · International Journal of Comparative Psychology · doi:10.46867/ijcp.2010.23.01.01 · Cited by 96 · see citing works

Behavioral performance altering effects of MK-801 in zebrafish (Danio rerio)

Sison, M., & Gerlai, R. T. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.02.019 · Cited by 95 · see citing works

Mental Health Care for Older Adults in the Year 2020: A Dangerous and Avoided Topic

Koenig, H. G., George, L. K., & Schneider, R. (1994) · The Gerontologist · doi:10.1093/geront/34.5.674 · Cited by 95 · see citing works

The psychotherapeutic potential of MDMA (3,4-methylenedioxymethamphetamine): An evidence-based review

Parrott, A. C. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0703-5 · Cited by 87 · see citing works

Serotonin Stimulates Hypothalamic mRNA Expression and Local Release of Neurohypophysial Peptides

Jørgensen, H., Kjær, A., Knigge, U., Møller, M., & Warberg, J. (2003) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2003.01032.x · Cited by 86 · see citing works

CRF–CRF1 Receptor System in the Central and Basolateral Nuclei of the Amygdala Differentially Mediates Excessive Eating of Palatable Food

Iemolo, A., Blasio, A., Cyr, S. A. S., Jiang, F., Rice, K. C., Sabino, V., & Cottone, P. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.147 · Cited by 82 · see citing works

Perspectives on experimental models of serotonin syndrome in zebrafish

Stewart, A., Cachat, J., Gaikwad, S., Robinson, K. S. L., Gebhardt, M. J., & Kalueff, A. V. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.02.018 · Cited by 79 · see citing works

Oxytocin: a therapeutic target for mental disorders

Matsuzaki, M., Matsushita, H., Tomizawa, K., & Matsui, H. (2012) · The Journal of Physiological Sciences · doi:10.1007/s12576-012-0232-9 · Cited by 79 · see citing works

Trends in depression and anxiety: men and women

Murphy, J. M. (1986) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1986.tb10576.x · Cited by 78 · see citing works

A behavioral and molecular analysis of ketamine in zebrafish

Zakhary, S. M., Ayubcha, D., Ansari, F., Kamran, K., Karim, M., Leheste, J. R., Horowitz, J. M., & Torres, G. (2010) · Synapse · doi:10.1002/syn.20830 · Cited by 78 · see citing works

Peripheral oxytocin administration buffers autonomic but not behavioral responses to environmental stressors in isolated prairie voles

Grippo, A. J., Pournajafi-Nazarloo, H., Sanzenbacher, L., Trahanas, D. M., McNeal, N., Clarke, D. A., Porges, S. W., & Sue Carter, C. (2012) · Stress · doi:10.3109/10253890.2011.605486 · Cited by 74 · see citing works

Vagus nerve stimulation (VNS): utility in neuropsychiatric disorders

George, M. S., Rush, A. J., Sackeïm, H. A., & Marangell, L. B. (2003) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145703003250 · Cited by 74 · see citing works

Neuroendocrine control of feeding behavior and psychomotor activity by neuropeptideY in fish

Matsuda, K., Sakashita, A., Yokobori, E., & Azuma, M. (2012) · Neuropeptides · doi:10.1016/j.npep.2012.09.006 · Cited by 72 · see citing works

Behavioral effects of MDMA (‘ecstasy’) on adult zebrafish

Stewart, A., Riehl, R., Wong, K., Green, J. B. A., Cosgrove, J., Vollmer, K., Kyzar, E. J., Hart, P. C., Allain, A. V., Cachat, J., et al. (2011) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328345f758 · Cited by 66 · see citing works

Domain interplay concept in animal models of neuropsychiatric disorders: A new strategy for high-throughput neurophenotyping research

Kalueff, A. V. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.11.011 · Cited by 66 · see citing works

Perspectives on Zebrafish Models of Hallucinogenic Drugs and Related Psychotropic Compounds

Neelkantan, N., Mikhaylova, A., Stewart, A., Arnold, R., Gjeloshi, V., Kondaveeti, D., Poudel, M. K., & Kalueff, A. V. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn400090q · Cited by 65 · see citing works

Autism and other Pervasive Developmental Disorders: Exploring the Dimensional View

Myhr, G. (1998) · The Canadian Journal of Psychiatry · doi:10.1177/070674379804300607 · Cited by 65 · see citing works

Zebrafish as an experimental model: strategies for developmental and molecular neurobiology studies

Key, B., & Devine, C. A. (2003) · Methods in Cell Science · doi:10.1023/b:mics.0000006849.98007.03 · Cited by 63 · see citing works

Cardiac regulation in the socially monogamous prairie vole

Grippo, A. J., Lamb, D. G., Carter, C. S., & Porges, S. W. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.09.037 · Cited by 62 · see citing works

Modeling the anxiety–depression continuum hypothesis in domestic fowl chicks

Sufka, K. J., Feltenstein, M. W., Warnick, J. E., Acevedo, E. O., Webb, H. E., & Cartwright, C. M. (2006) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3280115fac · Cited by 61 · see citing works

Non-peptide oxytocin agonists

Pitt, G. R. W., Batt, A. R., Haigh, R. M., Penson, A., Robson, P. A., Rooker, D. P., Tartar, A. L., Trim, J. E., Yea, C., & Roe, M. B. (2004) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2004.04.107 · Cited by 61 · see citing works

Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain

Cruz, S. A., Tseng, Y., Kaiya, H., & Hwang, P. (2010) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2010.01.019 · Cited by 60 · see citing works

Developing ‘integrative’ zebrafish models of behavioral and metabolic disorders

Nguyen, M., Yang, E., Neelkantan, N., Mikhaylova, A., Arnold, R., Poudel, M. K., Stewart, A., & Kalueff, A. V. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.08.012 · Cited by 59 · see citing works

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

Adams, L. M., & Geyer, M. A. (1985) · Behavioral Neuroscience · doi:10.1037//0735-7044.99.5.881 · Cited by 57 · see citing works

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

Adams, L. M., & Geyer, M. A. (1985) · Behavioral Neuroscience · doi:10.1037/0735-7044.99.5.881 · Cited by 57 · see citing works

Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats

Haque, Z., Akbar, N., Yasmin, F., Haleem, M. A., & Haleem, D. J. (2012) · Stress · doi:10.3109/10253890.2012.736047 · Cited by 56 · see citing works

Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management

Halpern, C. H., Torres-Martinez, N., Hurtig, H. I., Wolf, J. A., Stephen, J. H., Oh, M. Y., Williams, N. N., Dichter, M. A., Jaggi, J. L., Caplan, A. L., et al. (2011) · Acta Neurochirurgica · doi:10.1007/s00701-011-1166-3 · Cited by 56 · see citing works

α‐Melanocyte‐Stimulating Hormone and Oxytocin: A Peptide Signalling Cascade in the Hypothalamus

Sabatier, N. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01464.x · Cited by 54 · see citing works

Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations

Wudarczyk, O. A., Earp, B. D., Guastella, A., & Savulescu, J. (2013) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3283642e10 · Cited by 52 · cited 2× · see citing works

Anxiety in a transgenic mouse model of cortical-limbic neuropotentiated compulsive behavior

McGrath, M. J., Campbell, K. M., Veldman, M. B., & Burton, F. H. (1999) · Behavioural Pharmacology · doi:10.1097/00008877-199909000-00001 · Cited by 49 · see citing works

Constructing the habituome for phenotype-driven zebrafish research

Stewart, A., Cachat, J., Green, J. B. A., Gaikwad, S., Kyzar, E. J., Roth, A. J. L., Davis, A., Collins, C. J., El-Ounsi, M., Pham, M., et al. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.08.026 · Cited by 49 · see citing works

Headache and anxiety–depressive disorder comorbidity: the HADAS study

Beghi, E., Allais, G., Cortelli, P., D’Amico, D., Simone, R. D., d’Onofrio, F., Genco, S., Manzoni, G. C., Moschiano, F., Tonini, M. C., et al. (2007) · Neurological Sciences · doi:10.1007/s10072-007-0780-6 · Cited by 49 · see citing works

Orexin System in Teleost Fish

Matsuda, K., Azuma, M., & Kang, K. S. (2012) · Vitamins and hormones · doi:10.1016/b978-0-12-394623-2.00018-4 · Cited by 48 · see citing works

Obsessive-Compulsive Disorder and Comorbid Anxiety Problems in a National Anxiety Screening Sample

Welkowitz, L. A., Struening, E. L., Pittman, J. G., Guardino, M., & Welkowitz, J. (2000) · Journal of Anxiety Disorders · doi:10.1016/s0887-6185(00)00034-7 · Cited by 46 · see citing works

Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity

Üçeyler, N., Schütt, M., Palm, F., et al. (2010) · International Journal of Obesity · doi:10.1038/ijo.2009.289 · Cited by 46 · see citing works

Modelling the anxiety-depression continuum in chicks

Warnick, J. E., Huang, C., Acevedo, E. O., & Sufka, K. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108089805 · Cited by 44 · see citing works

Effects of 3,4-methylenedioxy-methamphetamine (MDMA) on anxiety in mice tested in the light-dark box

Maldonado, E., & Navarro, J. F. (2000) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00112-8 · Cited by 43 · see citing works

Effect of vagal nerve stimulation in a case of Tourette's syndrome and complex partial epilepsy

Diamond, A. L., Kenney, C., & Jankovic, J. J. (2006) · Movement Disorders · doi:10.1002/mds.20949 · Cited by 39 · see citing works

Dietary restriction changes behaviours in brain‐derived neurotrophic factor heterozygous mice: role of serotonergic system

Koizumi, H., Hashimoto, K., & Iyo, M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05094.x · Cited by 37 · see citing works

Aberrant nest building and prolactin secretion in vitamin D receptor mutant mice

Keisala, T., Minasyan, A., Järvelin, U., Wang, J., Hämäläinen, T. M., Kalueff, A. V., & Tuohimaa, P. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.03.031 · Cited by 35 · see citing works

Increased body mass index makes an impact on brain white-matter integrity in adults with remitted first-episode mania

Kuswanto, C. N., Sum, M. Y., Yang, G. L., Nowinski, W. L., McIntyre, R. S., & Sim, K. (2013) · Psychological Medicine · doi:10.1017/s0033291713000858 · Cited by 34 · see citing works

Deep brain stimulation affects conditioned and unconditioned anxiety in different brain areas

van Dijk, A., Klanker, M., van Oorschot, N., Post, R. A. G., Hamelink, R., Feenstra, M. G. P., & Denys, D. A. J. P. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.56 · Cited by 33 · see citing works

Receptor Pharmacology of MDMA and Related Hallucinogensa

Teitler, M., Leonhardt, S., Appel, N. M., Souza, E. B. D., & Glennon, R. A. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb16915.x · Cited by 33 · see citing works

Deep brain stimulation for treatment-resistant depression: A psychiatric perspective

Giacobbe, P., & Kennedy, S. H. (2006) · Current Psychiatry Reports · doi:10.1007/s11920-006-0048-5 · Cited by 32 · see citing works

Emergence of anxiety-like behaviours in depressive-like Cpefat/fat mice

Rodriguiz, R. M., Wilkins, J. J., Creson, T. K., Biswas, R., Berezniuk, I., Fricker, A. D., Fricker, L. D., & Wetsel, W. C. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000059 · Cited by 32 · see citing works

Qui non proficit, deficit: Experimental models for ‘integrative’ research of affective disorders

LaPorte, J. L., Egan, R. J., Hart, P. C., Bergner, C., Cachat, J., Canavello, P. R., & Kalueff, A. V. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.04.010 · Cited by 32 · see citing works

Autism and autistic spectrum disorders in the context of new DSM-V classification, and clinical and epidemiological data

Stanković, M., Lakić, A., & Ilic, N. (2012) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh1204236s · Cited by 30 · see citing works

Oxytocinergic regulation of endogenous as well as drug-induced mood

Broadbear, J. H., Kabel, D., Tracy, L. M., & Mak, P. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.07.002 · Cited by 30 · see citing works

Longitudinal Association Between Marital Disruption and Child BMI and Obesity

Arkes, J. A. (2012) · Obesity · doi:10.1038/oby.2012.84 · Cited by 29 · see citing works

Activation of signaling pathways downstream of the brain-derived neurotrophic factor receptor, TrkB, in the rat brain by vagal nerve stimulation and antidepressant drugs

Carreno, F. R., & Frazer, A. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000977 · Cited by 29 · see citing works

Screening antidepressants in the chick separation-stress paradigm

Feltenstein, M. W., & Sufka, K. J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2227-1 · Cited by 28 · see citing works

Refining psychiatric genetics: from ‘mouse psychiatry’ to understanding complex human disorders

LaPorte, J. L., Ren‐Patterson, R. F., Murphy, D. L., & Kalueff, A. V. (2008) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32830dc09b · Cited by 28 · see citing works

A primate model for the study of hallucinogens

Schlemmer, R. F., & Davis, J. M. (1986) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(86)90368-0 · Cited by 25 · see citing works

Benzodiazepine receptor function in the chick social separation-stress procedure.

Watson, G. S., Roach, J. T., & Sufka, K. J. (1999) · Experimental and Clinical Psychopharmacology · doi:10.1037//1064-1297.7.2.83 · Cited by 24 · see citing works

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

岡, 岳. (2011) · Institutional Repositories DataBase (IRDB) · Cited by 24 · see citing works

Benzodiazepine receptor function in the chick social separation–stress procedure.

Watson, G. S., Roach, J. T., & Sufka, K. J. (1999) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.7.2.83 · Cited by 24 · see citing works

Phenotyping of Zebrafish Homebase Behaviors in Novelty-Based Tests

Stewart, A., Cachat, J., Wong, K., et al. (2010) · Neuromethods · doi:10.1007/978-1-60761-953-6_12 · Cited by 16 · see citing works

Antidepressant‐like effects of ecstasy in subjects with a predisposition to depression

Majumder, I., White, J. M., & Irvine, R. J. (2012) · Addictive Behaviors · doi:10.1016/j.addbeh.2012.05.022 · Cited by 15 · see citing works

Experimental models for anxiolytic drug discovery in the era ofomesandomics

Stewart, A., Gaikwad, S., Hart, P. C., Kyzar, E. J., Roth, A., & Kalueff, A. V. (2011) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2011.586028 · Cited by 15 · see citing works

Deep Brain Stimulation as a Therapy for Alcohol Addiction

Münte, T. F., Heinze, H., & Visser-Vandewalle, V. E. R. M. (2012) · Current topics in behavioral neurosciences · doi:10.1007/978-3-642-28720-6_207 · Cited by 12 · see citing works

Enhancing action of LSD on neuronal responsiveness to serotonin in a brain structure involved in obsessive–compulsive disorder

Zghoul, T., & Blier, P. (2003) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702003218 · Cited by 12 · see citing works

Novel experimental models and paradigms for neuropsychiatric disorders: Editorial

Kalueff, A. V., & Schmidt, M. V. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.12.014 · Cited by 11 · see citing works

Neural melanocortin receptors are differentially expressed and regulated by stress in rat hypothalamic-pituitary-adrenal axis.

Wachira, S. J., Hughes‐Darden, C., Nicholas, H. B., et al. (2004) · PubMed · Cited by 10 · see citing works

Controlled substances and innovation of biomedicine: a preclinical perspective

Stewart, A., & Kalueff, A. V. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3530-c1 · Cited by 9 · see citing works

The LSD syndrome. A review.

Eveloff, H. H. (1968) · PubMed · Cited by 8 · see citing works

Therapeutic Effects of Hallucinogens

Winkelman, M. (1991) · Anthropology of Consciousness · doi:10.1525/ac.1991.2.3-4.15 · Cited by 5 · see citing works

Genome-Wide Expression Studies in Autism-Spectrum Disorders: Moving from Neurodevelopment to Neuroimmunology

Sacco, R., Persico, A. M., Garbett, K. A., & Mirnics, K. (2010) · Advances in neurobiology · doi:10.1007/978-1-4419-7197-5_18 · Cited by 3 · see citing works

Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

Sartori, S. B., & Singewald, N. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107402 · Cited by 236 · see citing works

Cytokine and endocrine parameters in mouse chronic social defeat: Implications for translational ‘cross-domain’ modeling of stress-related brain disorders

Stewart, A. M., Roy, S., Wong, K., Gaikwad, S., Chung, K. M., & Kalueff, A. V. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.08.037 · Cited by 44 · see citing works

Scope Management

Sherif, M. H. (2006) · doi:10.1002/9780470047682.ch4

Define the Many Aspects of What Is In Scope and Out of Scope

Mochal, T., & Mochal, J. (2011) · Apress eBooks · doi:10.1007/978-1-4302-3835-5_10

Study on the Enlargement of Accepting Scope of Administative Procedure

Ya-ping, J. (2004) · Hebei faxue

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(2022) · Oxford University Press eBooks · doi:10.1093/law/9780198871095.003.0010

From Optimal Scope to the Greater Optimal Scope-Linear Optimization of Rational Enterprise scope

Xiao, D. (2003) · Yunchou yu guanli