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Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice

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Bureau, Ingrid, Shepherd, Gordon M. G., Svoboda, Karel·2008·The Journal of Neuroscience

DOI 10.1523/jneurosci.1076-08.2008PMC PMC2696604

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Abstract

Silencing of the Fmr1 gene causes fragile X syndrome. Although defects in synaptic plasticity in the cerebral cortex have been linked to cognitive impairments in Fmr1 knock-out(ko) mice, the specific cortical circuits affected in the syndrome are unknown. Here, we investigated the development of excitatory projections in the barrel cortex of Fmr1 ko mice. In 2-week-old Fmr1 ko mice, a major ascending projection connecting layer 4 (L4) to L3 (L4→L3), was defective in multiple and independent ways: its strength was reduced, caused by a lower connection probability; the axonal arbors of L4 cells were spatially diffuse in L2/3; the L4→L3 projection did not show experience-dependent plasticity. By 3 weeks, the strength of the L4→L3 projection was similar to that of wild type. Our data indicate that Fmr1 shapes sensory cortical circuits during a developmental critical period.

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Santos, S. E. D., Porfírio, J., Cunha, F., Manger, P. R., Tavares, W. C., Pessôa, L. M., Raghanti, M. A., Sherwood, C. C., & Herculano‐Houzel, S. (2017) · Brain Behavior and Evolution · doi:10.1159/000452856 · Cited by 2,652
NeuN, a neuronal specific nuclear protein in vertebratesxs
Mullen, R. J., Buck, C. R., & Smith, A. M. (1992) · Development · doi:10.1242/dev.116.1.201 · Cited by 2,351
The structural organization of layer IV in the somatosensory region (S I) of mouse cerebral cortex
Woolsey, T. A., & Van der Loos, H. (1970) · Brain Research · doi:10.1016/0006-8993(70)90079-x · Cited by 2,254
The mGluR theory of fragile X mental retardation
Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.04.009 · Cited by 1,580
Altered synaptic plasticity in a mouse model of fragile X mental retardation
Huber, K. M., Gallagher, S. M., Warren, S. T., & Bear, M. F. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122205699 · Cited by 1,349
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome
Brown, V., Jin, P., Ceman, S., Darnell, J. C., O'Donnell, W. T., Tenenbaum, S. A., Jin, X., Feng, Y., Wilkinson, K. D., Keene, J. D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00568-2 · Cited by 1,109
Fmr1 knockout mice: A model to study fragile X mental retardation
THEDUTCHBELGIANFRAGILEXCONSOR (1994) · Cell · doi:10.1016/0092-8674(94)90569-x · Cited by 1,108
Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5401 · Cited by 1,046
Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression.
Huber, K., Kayser, M., & Bear, M. (2000) · Science · doi:10.1126/science.288.5469.1254 · Cited by 1,015
Correction of Fragile X Syndrome in Mice
Dölen, G., Osterweil, E., Rao, B. S. S., Smith, G. B., Auerbach, B. D., Chattarji, S., & Bear, M. F. (2007) · Neuron · doi:10.1016/j.neuron.2007.12.001 · Cited by 979
Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo
Lendvai, B., Stern, E. A., Chen, B., & Svoboda, K. (2000) · Nature · doi:10.1038/35009107 · Cited by 802
Self-citation
FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding
Ashley, C. T., Wilkinson, K. D., Reines, D., & Warren, S. T. (1993) · Science · doi:10.1126/science.7692601 · Cited by 752
Synaptic connections between layer 4 spiny neurone-layer 2/3 pyramidal cell pairs in juvenile rat barrel cortex: physiology and anatomy of interlaminar signalling within a cortical column.
Feldmeyer, D., Lübke, J., Silver, R. A., & Sakmann, B. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.012959 · Cited by 656
Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function
Zhang, Y., Bailey, A. M., Matthies, H. J. G., Renden, R., Smith, M. A., Speese, S. D., Rubin, G. M., & Broadie, K. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00589-x · Cited by 651
The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein.
Siomi, H., Siomi, M. C., Nussbaum, R. L., & Dreyfuss, G. (1993) · Cell · doi:10.1016/0092-8674(93)90420-u · Cited by 641
Dendritic Spine Structural Anomalies in Fragile-X Mental Retardation Syndrome
Irwin, S. A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.1038 · Cited by 626
Map Plasticity in Somatosensory Cortex
Feldman, D. E., & Brecht, M. (2005) · Science · doi:10.1126/science.1115807 · Cited by 587
Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium.
(1994) · PubMed · Cited by 565
Abnormal Development of Dendritic Spines in FMR1 Knock-Out Mice
Nimchinsky, E. A., Oberlander, A. M., & Svoboda, K. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05139.2001 · Cited by 560
Self-citation
FMRP Associates with Polyribosomes as an mRNP, and the I304N Mutation of Severe Fragile X Syndrome Abolishes This Association
Feng, Y., Absher, D., Eberhart, D. E., Brown, V., Malter, H. E., & Warren, S. T. (1997) · Molecular Cell · doi:10.1016/s1097-2765(00)80012-x · Cited by 511
A Decade of Molecular Studies of Fragile X Syndrome
O'Donnell, W. T., & Warren, S. T. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142909 · Cited by 487
A critical period for experience-dependent synaptic plasticity in rat barrel cortex
Fox, K. D. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-05-01826.1992 · Cited by 420
Deletion of FMR1 in Purkinje Cells Enhances Parallel Fiber LTD, Enlarges Spines, and Attenuates Cerebellar Eyelid Conditioning in Fragile X Syndrome
Koekkoek, S. K. E., Yamaguchi, K., Milojkovic, B. A., Dortland, B. R., Ruigrok, T. J. H., Maex, R., Graaf, W. D., Smit, A. E., VanderWerf, F., Bakker, C. E., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.07.005 · Cited by 412
Two Coincidence Detectors for Spike Timing-Dependent Plasticity in Somatosensory Cortex
Bender, V. A., Bender, K. J., Brasier, D. J., & Feldman, D. E. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0176-06.2006 · Cited by 373
Understanding the molecular basis of fragile X syndrome
Jin, P. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.6.901 · Cited by 369
Altered anxiety‐related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome
Spencer, C. M., Alekseyenko, O., Serysheva, E., Yuva‐Paylor, L. A., & Paylor, R. (2005) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2005.00123.x · Cited by 349
Fragile X mice develop sensory hyperreactivity to auditory stimuli
Chen, L., & Toth, M. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00036-7 · Cited by 345
A developmental switch in the signaling cascades for LTP induction
Yasuda, H., Barth, A. L., Stellwagen, D., & Malenka, R. C. (2003) · Nature Neuroscience · doi:10.1038/nn985 · Cited by 325
Circuit analysis of experience-dependent plasticity in the developing rat barrel cortex
Shepherd, G. M. G., Pologruto, T. A., & Svoboda, K. (2003) · Neuron · doi:10.1016/s0896-6273(03)00152-1 · Cited by 322
Self-citation
Decreased expression of the GABAA receptor in fragile X syndrome
D'Hulst, C., De Geest, N., Reeve, S. P., Van Dam, D., De Deyn, P. P., Hassan, B. A., & Kooy, R. F. (2006) · Brain Research · doi:10.1016/j.brainres.2006.08.115 · Cited by 318
Synaptic regulation of protein synthesis and the fragile X protein
Greenough, W. T., Klintsova, A. Y., Irwin, S. A., Galvez, R., Bates, K. E., & Weiler, I. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.141145998 · Cited by 317
Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function
Paradee, W., Melikian, H. E., Rasmussen, D. L., Kenneson, A., Conn, P. J., & Warren, S. T. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00285-7 · Cited by 305 · cited 2×
“Fmr1 ko mice have learning deficits (Dutch–Belgian Fragile X Consortium, 1994; Paradee et al., 1999; Peier et al., 2000), abnormal social behaviors (Spencer et al., 2005; Mineur et al., 2006), and audiogenic seizures (Musumeci et al., 2000; Chen and Toth, 2001; Yan et al., 2004).”
Background
Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome
Zhao, M.-G., Toyoda, H., Ko, S. W., Ding, H.-K., Wu, L.-J., & Zhuo, M. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1520-05.2005 · Cited by 296
Audiogenic Seizures Susceptibility in Transgenic Mice with Fragile X Syndrome
Musumeci, S. A., Bosco, P., Calabrese, G., Bakker, C., De Sarro, G. B., Elia, M., Ferri, R., & Oostra, B. A. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb01499.x · Cited by 289
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
Darnell, J. C., Fraser, C. E., Mostovetsky, O., Stefani, G., Jones, T. A., Eddy, S. R., & Darnell, R. B. (2005) · Genes & Development · doi:10.1101/gad.1276805 · Cited by 287
(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features
Peier, A. M. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.8.1145 · Cited by 285
Rapid Development and Plasticity of Layer 2/3 Maps in Rat Barrel Cortex In Vivo
Stern, E. A., Maravall, M., & Svoboda, K. (2001) · Neuron · doi:10.1016/s0896-6273(01)00360-9 · Cited by 282
Self-citation
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95
Todd, P. K., Mack, K. J., & Malter, J. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2336265100 · Cited by 280
Reduced Cortical Synaptic Plasticity and GluR1 Expression Associated with Fragile X Mental Retardation Protein Deficiency
Li, J., Pelletier, M. R., Perez-Velazquez, J. L., & Carlen, P. L. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2001.1085 · Cited by 275
Interdigitated Paralemniscal and Lemniscal Pathways in the Mouse Barrel Cortex
Bureau, I., Paul, F. V. S., & Svoboda, K. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040382 · Cited by 274
Self-citation
Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them
Siomi, M. C., Zhang, Y., Siomi, H., & Dreyfuss, G. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.7.3825 · Cited by 271
Long-term depression induced by sensory deprivation during cortical map plasticity in vivo
Allen, C. B., Celikel, T., & Feldman, D. E. (2003) · Nature Neuroscience · doi:10.1038/nn1012 · Cited by 270
Sensory experience modifies the short-term dynamics of neocortical synapses
Finnerty, G. T., Roberts, L., & Connors, B. W. (1999) · Nature · doi:10.1038/22553 · Cited by 264
Cerebellar LTD and Learning-Dependent Timing of Conditioned Eyelid Responses
Koekkoek, S. K. E., Hulscher, H. C., Dortland, B. R., Hensbroek, R. A., Elgersma, Y., Ruigrok, T. J. H., & Zeeuw, C. I. D. (2003) · Science · doi:10.1126/science.1088383 · Cited by 263
Geometric and functional organization of cortical circuits
Shepherd, G. M., Stepanyants, A., Bureau, I., Chklovskii, D. B., & Svoboda, K. (2005) · Nature Neuroscience · doi:10.1038/nn1447 · Cited by 259
Self-citation
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses
Antar, L. N., Li, C., Zhang, H., Carroll, R. C., & Bassell, G. J. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.02.001 · Cited by 259
High-Probability Uniquantal Transmission at Excitatory Synapses in Barrel Cortex
Silver, R. A., Lübke, J. H. R., Sakmann, B. J., & Feldmeyer, D. (2003) · Science · doi:10.1126/science.1087160 · Cited by 247
Major defects in neocortical GABAergic inhibitory circuits in mice lacking the fragile X mental retardation protein
Selby, L., Zhang, C., & Sun, Q.-Q. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2006.11.062 · Cited by 245
Laminar and Columnar Organization of Ascending Excitatory Projections to Layer 2/3 Pyramidal Neurons in Rat Barrel Cortex
Shepherd, G. M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1173-05.2005 · Cited by 244
Self-citation
Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome
Galvez, R., & Greenough, W. T. (2005) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.30709 · Cited by 231
Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters
Canepari, M., Nelson, L., Papageorgiou, G., Corrie, J. E. T., & Ogden, D. (2001) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(01)00451-4 · Cited by 216
A phenotypic and molecular characterization of the fmr1‐tm1Cgr Fragile X mouse
Yan, Q. J., Asafo‐Adjei, P. K., Arnold, H. M., Brown, R. E., & Bauchwitz, R. P. (2004) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2004.00087.x · Cited by 213
Molecular-clinical correlations in males with an expanded FMR1 mutation
Merenstein, S. A., Sobesky, W. E., Taylor, A. K., Riddle, J. E., Tran, H. X., & Hagerman, R. J. (1996) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19960809)64:2 · Cited by 213
Decreased GABAA receptor expression in the seizure-prone fragile X mouse
Idrissi, A. E., Ding, X., Scalia, J., Trenkner, E., Brown, W. T., & Dobkin, C. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.11.087 · Cited by 210
Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines
Grossman, A. W., Elisseou, N. M., McKinney, B. C., & Greenough, W. T. (2006) · Brain Research · doi:10.1016/j.brainres.2006.02.044 · Cited by 206
Morphometric Analysis of the Columnar Innervation Domain of Neurons Connecting Layer 4 and Layer 2/3 of Juvenile Rat Barrel Cortex
Lübke, J. H. R. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.10.1051 · Cited by 202
Immunocytochemical and Biochemical Characterization of FMRP, FXR1P, and FXR2P in the Mouse
Bakker, C. E., de Diego‐Otero, Y., Bontekoe, C. J. M., Raghoe, P., Luteijn, T., Hoogeveen, A. T., Oostra, B. A., & Willemsen, R. (2000) · Experimental Cell Research · doi:10.1006/excr.2000.4932 · Cited by 198
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation
Pfeiffer, B. E., & Huber, K. M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0054-07.2007 · Cited by 189
Developmental Switch in Synaptic Mechanisms of Hippocampal Metabotropic Glutamate Receptor-Dependent Long-Term Depression
Nosyreva, E. D., & Huber, K. M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3652-04.2005 · Cited by 186
Dendritic spine abnormalities in the occipital cortex of C57BL/6Fmr1 knockout mice
McKinney, B. C., Grossman, A. W., Elisseou, N. M., & Greenough, W. T. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30183 · Cited by 184
Social behavior deficits in the Fmr1 mutant mouse
Mineur, Y. S., Huynh, L. X., & Crusio, W. E. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.11.004 · Cited by 177
Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex
Crozier, R. A., Wang, Y., Liu, C.-H., & Bear, M. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609596104 · Cited by 163
Precise Development of Functional and Anatomical Columns in the Neocortex
Bureau, I., Shepherd, G. M., & Svoboda, K. (2004) · Neuron · doi:10.1016/j.neuron.2004.05.002 · Cited by 149
Self-citation
FMRP Involvement in Formation of Synapses among Cultured Hippocampal Neurons
Braun, K. A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.1045 · Cited by 149
Defective Neuronal Development in the Mushroom Bodies of Drosophila Fragile X Mental Retardation 1 Mutants
Michel, C. I., Kraft, R., & Restifo, L. L. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1102-04.2004 · Cited by 145
Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors
Kemp, N. M. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(98)00222-6 · Cited by 141
Synaptic basis for developmental plasticity in somatosensory cortex
Foeller, E., & Feldman, D. E. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.01.011 · Cited by 136
Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein
Larson, J., Jessen, R. E., Kim, D., Fine, A.-K. S., & du Hoffmann, J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2638-05.2005 · Cited by 135
Synaptic basis for whisker deprivation-induced synaptic depression in rat somatosensory cortex
Bender, K. J., Allen, C. B., Bender, V. A., & Feldman, D. E. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0175-06.2006 · Cited by 126
Axonal trajectories between mouse somatosensory thalamus and cortex
Bernardo, K. L., & Woolsey, T. A. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902580406 · Cited by 121
Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice
Wilson, B. M., & Cox, C. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610875104 · Cited by 121
Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors
Wang, H. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddh009 · Cited by 117
Early Postnatal Plasticity in Neocortex of Fmr1 Knockout Mice
Desai, N. S., Casimiro, T. M., Gruber, S. M., & Vanderklish, P. W. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00221.2006 · Cited by 113
Development of Columnar Topography in the Excitatory Layer 4 to Layer 2/3 Projection in Rat Barrel Cortex
Bender, K. J., Rangel, J., & Feldman, D. E. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08759.2003 · Cited by 108
PresynapticFmr1Genotype Influences the Degree of Synaptic Connectivity in a Mosaic Mouse Model of Fragile X Syndrome
Hanson, J. E., & Madison, D. V. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4717-06.2007 · Cited by 103
Angelman Syndrome
Guerrini, R., Carrozzo, R., Rinaldi, R., & Bonanni, P. (2003) · Pediatric Drugs · doi:10.2165/00148581-200305100-00001 · Cited by 95
Organization of excitatory and inhibitory local networks in the caudal nucleus of tractus solitarius of rats revealed in in vitro slice preparation
Kawai, Y., & Senba, E. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960923)373:3 · Cited by 88
Developmental Changes in AMPA and Kainate Receptor-Mediated Quantal Transmission at Thalamocortical Synapses in the Barrel Cortex
Bannister, N. J., Benke, T. A., Mellor, J. R., Scott, H. L., Gürdal, E., Crabtree, J. W., & Isaac, J. T. R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0827-05.2005 · Cited by 49
The Neurobiology of Tuberous Sclerosis Complex
Ess, K. C. (2006) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2006.01.009 · Cited by 47
Clinical consult: developmental delay/fragile X syndrome
Wiesner, G. L., Cassidy, S. B., Grimes, S. J., Matthews, A. L., & Acheson, L. S. (2004) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2004.04.008 · Cited by 7
Medical records in the governmental hospitals, Gaza Strip, Palestine.
Ah, R. (2000) · PubMed · Cited by 3
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Irwin (2001) · doi:10.1002/1096-8628(20010115)98:2

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Authors: Bureau, I., Shepherd, G. M. G., & Svoboda, K.
Affiliations: Howard Hughes Medical Institute (US)
Corresponding author: Bureau, Ingrid
ORCID: Bureau, Ingrid
Shepherd, Gordon M. G.
Svoboda, Karel
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2008-05-14
Volume: 28
Issue: 20
Pages: 5178-5188
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.1076-08.2008
PMC: PMC2696604
OpenAlex: W1966371094
Cited by: 201
References: 82
Citations by year: 2026: 3 · 2025: 6 · 2024: 8 · 2023: 8 · 2022: 6 · 2021: 14 · 2020: 14 · 2019: 8 · 2018: 8 · 2017: 11 · 2016: 8 · 2015: 13 · 2014: 14 · 2013: 12 · 2012: 17
FWCI: 9.69
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 184 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (acceptedVersion)
HAL (submittedVersion)
Funders: Howard Hughes Medical Institute
FRAXA Research Foundation
National Institutes of Health
National Institute of Neurological Disorders and Stroke (R01NS038259)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords: FMR1 gene, fragile X syndrome, Fmr1 knockout mice, barrel cortex, somatosensory cortex, cortical circuit development, synaptic plasticity, axonal arbors, experience-dependent plasticity, critical period, connection probability
MeSH terms: Animals, Disease Models, Animal, Fragile X Syndrome, Male, Mice, Inbred C57BL, Nervous System Malformations, Neural Pathways, Synaptic Transmission, Neuronal Plasticity, Organ Culture Techniques, Sensation, Somatosensory Cortex, Mice, Knockout, Gene Expression Regulation, Developmental, Excitatory Postsynaptic Potentials, Genetic Predisposition to Disease, Growth Cones, Mice, Fragile X Messenger Ribonucleoprotein 1

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Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice

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