The skeletal consequences of thyrotoxicosis

Risk Factors for Hip Fracture in White Women

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Physiological and Molecular Basis of Thyroid Hormone Action

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Evidence for osteocyte regulation of bone homeostasis through RANKL expression

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Singapore Medical Journal

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Cellular and molecular mechanisms of bone remodeling

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Molecular Aspects of Thyroid Hormone Actions

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Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

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Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

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Deiodinases: implications of the local control of thyroid hormone action

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TSH Is a Negative Regulator of Skeletal Remodeling

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Risk for fracture in women with low serum levels of thyroid-stimulating hormone

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Effects of thyroid hormones on bone and mineral metabolism

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Direct stimulation of bone resorption by thyroid hormones.

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Changes in bone mass during prolonged subclinical hyperthyroidism due to l-thyroxine treatment: a meta-analysis

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Mortality after the Treatment of Hyperthyroidism with Radioactive Iodine

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Mechanism of Thyroid Hormone Action

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Hyperthyroidism, Bone Mineral, and Fracture Risk—A Meta-Analysis

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Contrasting developmental and tissue‐specific expression of alpha and beta thyroid hormone receptor genes.

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Defining the Roles of the Iodothyronine Deiodinases: Current Concepts and Challenges

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Fractures in Patients with Hyperthyroidism and Hypothyroidism: A Nationwide Follow-Up Study in 16,249 Patients

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Genetic Analysis Reveals Different Functions for the Products of the Thyroid Hormone Receptor α Locus

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Long-Term Growth in Juvenile Acquired Hypothyroidism:

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Major Genetic Influence on the Regulation of the Pituitary-Thyroid Axis: A Study of Healthy Danish Twins

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The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

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Osteoblasts mediate thyroid hormone stimulation of osteoclastic bone resorption.

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Predictors of ankle and foot fractures in older women

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Long-term thyroxine treatment and bone mineral density.

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The TSH receptor reveals itself

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Critical role for thyroid hormone receptor β2 in the regulation of paraventricular thyrotropin-releasing hormone neurons

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Osteocytes inhibit osteoclastic bone resorption through transforming growth factor‐β: Enhancement by estrogen*

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Thyroid Hormone Acts Directly on Growth Plate Chondrocytes to Promote Hypertrophic Differentiation and Inhibit Clonal Expansion and Cell Proliferation¹

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The Thyroid Epidemiology, Audit, and Research Study (TEARS): Morbidity in Patients with Endogenous Subclinical Hyperthyroidism

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Thyroid Function within the Upper Normal Range Is Associated with Reduced Bone Mineral Density and an Increased Risk of Nonvertebral Fractures in Healthy Euthyroid Postmenopausal Women

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Bone mineral density in patients with endogenous subclinical hyperthyroidism: Is this thyroid status a risk factor for osteoporosis?

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Thyroxine prescription in the community: serum thyroid stimulating hormone level assays as an indicator of undertreatment or overtreatment.

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Thyroid Hormone Excess Rather Than Thyrotropin Deficiency Induces Osteoporosis in Hyperthyroidism

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The thyroid and the skeleton

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Thyroid Hormones Regulate Hypertrophic Chondrocyte Differentiation and Expression of Parathyroid Hormone-Related Peptide and Its Receptor During Endochondral Bone Formation

Stevens, D. A., Hasserjian, R. P., Robson, H., Siebler, T., Shalet, S. M., & Williams, G. R. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.12.2431 · Cited by 158 · see citing works

Normalization of serum thyrotrophin by means of radioiodine treatment in subclinical hyperthyroidism: effect on bone loss in postmenopausal women

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Functional Interference between Thyroid Hormone Receptor α (TRα) and Natural Truncated TRΔα Isoforms in the Control of Intestine Development

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Measurement of Bone Collagen Degradation in Hyperthyroidism and During Thyroxine Replacement Therapy Using Pyridinium Cross-Links as Specific Urinary Markers*

Harvey, R., McHardy, K. C., REID, I. W., Paterson, F., Bewsher, P. D., Duncan, A., & Robins, S. P. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-6-1189 · Cited by 150 · see citing works

Markers of bone turnover in hyperthyroidism and the effects of treatment

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A Tetracycline‐Based Histomorphometric Evaluation of Bone Resorption and Bone Turnover in Hyperthyroidism and Hyperparathyroidism

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Influence of Hyper- and Hypothyroidism, and the Effects of Treatment with Antithyroid Drugs and Levothyroxine on Fracture Risk

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Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts

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Thyroid-Stimulating Hormone Restores Bone Volume, Microarchitecture, and Strength in Aged Ovariectomized Rats*

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Critical role of the hypothalamic–pituitary–thyroid axis in bone

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Bone metabolism during anti‐thyroid drug treatment of endogenous subclinical hyperthyroidism

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The Effects of Thyrotropin-Suppressive Therapy on Bone Metabolism in Patients with Well-Differentiated Thyroid Carcinoma

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Subclinical Thyroid Dysfunction and Incident Hip Fracture in Older Adults

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Local control of thyroid hormone action: role of type 2 deiodinase

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Effects of serum TSH and FT4 levels and the TSHR‐Asp727Glu polymorphism on bone: the Rotterdam Study

van der Deure, W. M., Uitterlinden, A. G., Albert Hofman, D., Rivadeneira, F., Pols, H. A. P., Peeters, R. P., & Visser, T. J. (2007) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2007.03016.x · Cited by 132 · see citing works

Morbidity in patients on l ‐thyroxine: a comparison of those with a normal TSH to those with a suppressed TSH

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A Thyrotoxic Skeletal Phenotype of Advanced Bone Formation in Mice with Resistance to Thyroid Hormone

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Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters

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The association between serum thyroid-stimulating hormone in its reference range and bone status in postmenopausal American women

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Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort

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Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of β-catenin signaling

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The Relationship between Serum TSH and Bone Mineral Density in Men and Postmenopausal Women: The Tromsø Study

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TNFα mediates the skeletal effects of thyroid-stimulating hormone

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Recombinant human TSH modulates in vivo C-telopeptides of type-1 collagen and bone alkaline phosphatase, but not osteoprotegerin production in postmenopausal women monitored for differentiated thyroid carcinoma

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Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss

Sun, L., Vukičević, S., Baliram, R., Yang, G., Sendak, R. A., McPherson, J. M., Zhu, L.-L., Iqbal, J. Z., Latif, R., Natrajan, A., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712395105 · Cited by 126 · see citing works

Contrasting Skeletal Phenotypes in Mice with an Identical Mutation Targeted to Thyroid Hormone Receptor α1 or β

O’Shea, P. J., Bassett, J. H. D., Sriskantharajah, S., Ying, H., Cheng, S.-Y., & Williams, G. R. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0224 · Cited by 126 · see citing works

Thyroid Status during Skeletal Development Determines Adult Bone Structure and Mineralization

Bassett, J. H. D., Nordström, K., Boyde, A., Howell, P. G. T., Kelly, S., Vennström, B., & Williams, G. R. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0157 · Cited by 125 · see citing works

Persistent Increase in Bone Turnover in Graves’ Patients with Subclinical Hyperthyroidism

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Kinetics of trabecular bone resorption and formation in hypothyroidism: Evidence for a positive balance per remodeling cycle

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Special Features of Graves' Disease in Early Childhood

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Serum TSH values and risk of vertebral fractures in euthyroid post-menopausal women with low bone mineral density

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A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.

Bassett, J. H. D., Williams, A. J., Murphy, E., Boyde, A., Howell, P. G., Swinhoe, R., Archanco, M., Flamant, F., Samarut, J., Costagliola, S., et al. (2008) · Molecular Endocrinology · doi:10.1210/me.2007-0221 · Cited by 110 · see citing works

Thyroid Hormone Activates Fibroblast Growth Factor Receptor-1 in Bone

Stevens, D. A., Harvey, C. B., Scott, A. J., O’Shea, P. J., Barnard, J. C., Williams, A. J., Brady, G., Samarut, J., Chassande, O., & Williams, G. R. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0137 · Cited by 105 · see citing works

Low normal TSH levels are associated with low bone mineral density in healthy postmenopausal women

Kim, D. J., Khang, Y. H., Koh, J., Shong, Y. K., & Kim, G. S. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02422.x · Cited by 103 · see citing works

Prevention of bone loss induced by thyroxine suppressive therapy in postmenopausal women: the effect of calcium and calcitonin

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Low Thyrotropin Levels Are Not Associated with Bone Loss in Older Women: A Prospective Study

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The Effects of Recombinant TSH on Bone Turnover Markers and Serum Osteoprotegerin and RANKL Levels

Martini, G., Gennari, L., Paola, V. D., Pilli, T., Salvadori, S., Merlotti, D., Valleggi, F., Campagna, S., Franci, B., Avanzati, A., et al. (2008) · Thyroid · doi:10.1089/thy.2007.0166 · Cited by 91 · see citing works

Tri-iodothyronine stimulates rat osteoclastic bone resorption by an indirect effect

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Longitudinal changes of bone mineral density and bone turnover in postmenopausal women on thyroxine

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Thyroid Hormones Regulate Fibroblast Growth Factor Receptor Signaling during Chondrogenesis

Barnard, J. C., Williams, A. J., Rabier, B., Chassande, O., Samarut, J., Cheng, S.-Y., Bassett, J. H. D., & Williams, G. R. (2005) · Endocrinology · doi:10.1210/en.2005-0762 · Cited by 85 · see citing works

Insulin-Like Growth Factor I Production Is Essential for Anabolic Effects of Thyroid Hormone in Osteoblasts

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Hip fractures and the thyroid: a case‐control study

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A Longitudinal Study of Markers of Bone Turnover in Graves' Disease and Their Value in Predicting Bone Mineral Density

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The skeletal phenotypes of TRα and TRβ mutant mice

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Catch-up growth after prolonged hypothyroidism

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The Influence of Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Antibodies on Osteoclastogenesis

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Relationship between Subclinical Thyroid Dysfunction and Femoral Neck Bone Mineral Density in Women

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