Nanoparticle-Mediated Drug Delivery System for Cardiovascular Disease

Recent advances with liposomes as pharmaceutical carriers

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Heart Disease and Stroke Statistics—2014 Update

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PLGA-based nanoparticles: An overview of biomedical applications

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Myocardial Reperfusion Injury

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Myocardial ischemia-reperfusion injury: a neglected therapeutic target

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PPARγ signaling and metabolism: the good, the bad and the future

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Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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Block copolymer micelles: preparation, characterization and application in drug delivery

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Targeted drug delivery via the folate receptor

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Computed Tomographic Angiography Characteristics of Atherosclerotic Plaques Subsequently Resulting in Acute Coronary Syndrome

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Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

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Concept of Vulnerable/Unstable Plaque

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PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

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Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

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Introduction to metallic nanoparticles

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A Tale of Coronary Artery Disease and Myocardial Infarction

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Therapeutic siRNA silencing in inflammatory monocytes in mice

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Imaging macrophages with nanoparticles

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Nanomedicine therapeutic approaches to overcome cancer drug resistance

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Preclinical and clinical studies of anticancer agent‐incorporating polymer micelles

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Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

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Long-circulating (sterically stabilized) liposomes for targeted drug delivery

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Ly6 family proteins in neutrophil biology

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Nanoparticulate Assemblies of Amphiphiles and Diagnostically Active Materials for Multimodality Imaging

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Properties of a peptide containing dl-lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods

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Nanoparticle-Mediated Delivery of Pitavastatin Inhibits Atherosclerotic Plaque Destabilization/Rupture in Mice by Regulating the Recruitment of Inflammatory Monocytes

Katsuki, S., Matoba, T., Nakashiro, S., Sato, K., Koga, J.-I., Nakano, K., Nakano, Y., Egusa, S., Sunagawa, K., & Egashira, K. (2014) · Circulation · doi:10.1161/circulationaha.113.002870 · Cited by 179 · see citing works

High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis

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Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion

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How do carbon nanotubes serve as carriers for gemcitabine transport in a drug delivery system?

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Nanoparticle-Mediated Delivery of Nuclear Factor κB Decoy Into Lungs Ameliorates Monocrotaline-Induced Pulmonary Arterial Hypertension

Kimura, S., Egashira, K., Chen, L., Nakano, K., Iwata, E., Miyagawa, M., Tsujimoto, H., Hara, K., Morishita, R., Sueishi, K., et al. (2009) · Hypertension · doi:10.1161/hypertensionaha.108.121418 · Cited by 140 · see citing works

Formulation of Nanoparticle-Eluting Stents by a Cationic Electrodeposition Coating Technology

Nakano, K., Egashira, K., Masuda, S., Funakoshi, K., Zhao, G., Kimura, S., Matoba, T., Sueishi, K., Endo, Y., Kawashimà, Y., et al. (2009) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2008.08.023 · Cited by 139 · see citing works

Prolonged Targeting of Ischemic/Reperfused Myocardium by Liposomal Adenosine Augments Cardioprotection in Rats

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The neutrophil as a mediator of myocardial ischemia-reperfusion injury: time to move on

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Molecular Imaging of Coronary Atherosclerosis and Myocardial Infarction: Considerations for the Bench and Perspectives for the Clinic

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Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation

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Nanoparticle-Mediated Delivery of Pitavastatin Into Lungs Ameliorates the Development and Induces Regression of Monocrotaline-Induced Pulmonary Artery Hypertension

Chen, L., Nakano, K., Kimura, S., Matoba, T., Iwata, E., Miyagawa, M., Tsujimoto, H., Nagaoka, K., Kishimoto, J., Sunagawa, K., et al. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.157032 · Cited by 89 · see citing works

Optimizing Druggability through Liposomal Formulations: New Approaches to an Old Concept

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Visualization of Vascular Inflammation in the Atherosclerotic Mouse by Ultrasmall Superparamagnetic Iron Oxide Vascular Cell Adhesion Molecule-1–Specific Nanoparticles

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Pitavastatin-Incorporated Nanoparticle-Eluting Stents Attenuate In-Stent Stenosis without Delayed Endothelial Healing Effects in a Porcine Coronary Artery Model

Tsukie, N., Nakano, K., Matoba, T., Masuda, S., Iwata, E., Miyagawa, M., Zhao, G., Meng, W., Kishimoto, J., Sunagawa, K., et al. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.13862 · Cited by 71 · see citing works

Cells Involved in the Capture of Nanoparticles in Hematopoietic Organs

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Dendritic supramolecular assemblies for drug delivery

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Therapeutic Neovascularization by Nanotechnology-Mediated Cell-Selective Delivery of Pitavastatin Into the Vascular Endothelium

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Imatinib Mesylate-Incorporated Nanoparticle-Eluting Stent Attenuates In-Stent Neointimal Formation in Porcine Coronary Arteries

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Local Delivery of Imatinib Mesylate (STI571)-Incorporated Nanoparticle Ex Vivo Suppresses Vein Graft Neointima Formation

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Nanoparticle-Mediated Delivery of Pioglitazone Enhances Therapeutic Neovascularization in a Murine Model of Hindlimb Ischemia

Nagahama, R., Matoba, T., Nakano, K., Kim‐Mitsuyama, S., Sunagawa, K., & Egashira, K. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.253823 · Cited by 48 · see citing works

Nanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia

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Nanoparticle-Mediated Delivery of Anticancer Agents to Tumor Angiogenic Vessels

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Nanomedicine Captures Cardiovascular Disease

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Anti-inflammatory gene therapy for cardiovascular disease

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Diagnosis and Management of STEMI Arising From Plaque Erosion

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Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

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Recent applications of PLGA based nanostructures in drug delivery

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Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

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Application of the Nano-Drug Delivery System in Treatment of Cardiovascular Diseases

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Release mechanisms and applications of drug delivery systems for extended-release

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Targeted delivery of therapeutic agents to the heart

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Krüppel-like factors and vascular wall homeostasis

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Cell‐Based Drug Delivery and Use of Nano‐and Microcarriers for Cell Functionalization

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Highly Bright AIE Nanoparticles by Regulating the Substituent of Rhodanine for Precise Early Detection of Atherosclerosis and Drug Screening

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Bioinspired Negatively Charged Calcium Phosphate Nanocarriers for Cardiac Delivery of MicroRNAs

Mauro, V. D., Iafisco, M., Salvarani, N., Vacchiano, M., Carullo, P., Ramírez‐Rodríguez, G. B., Patrício, T., Tampieri, A., Miragoli, M., & Catalucci, D. (2016) · Nanomedicine · doi:10.2217/nnm.16.26 · Cited by 105 · see citing works

Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs

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Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques

Ostrowski, A., Nordmeyer, D., Boreham, A., Holzhausen, C., Mundhenk, L., Graf, C. M., Meinke, M. C., Vogt, A., Hadam, S., Lademann, J. M., et al. (2015) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.6.25 · Cited by 96 · see citing works

Baicalin-loaded PEGylated lipid nanoparticles: characterization, pharmacokinetics, and protective effects on acute myocardial ischemia in rats

Zhang, S., Wang, J., & Pan, J. (2016) · Drug Delivery · doi:10.1080/10717544.2016.1223218 · Cited by 93 · see citing works

Nanosystems in Cardiovascular Medicine: Advancements, Applications, and Future Perspectives

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Recent advances in PLGA based nanocarriers for drug delivery system: a state of the art review

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Nanomaterials as Promising Theranostic Tools in Nanomedicine and Their Applications in Clinical Disease Diagnosis and Treatment

Zhu, W., Wei, Z., Chang, H., & Weng, X. (2021) · Nanomaterials · doi:10.3390/nano11123346 · Cited by 71 · see citing works

Recent advances on nanoparticle-based therapies for cardiovascular diseases

Soumya, R. S., & Raghu, K. G. (2022) · Journal of Cardiology · doi:10.1016/j.jjcc.2022.02.009 · Cited by 68 · see citing works

Nanoparticle Based Treatment for Cardiovascular Diseases

Gupta, P., Garcia, E., Sarkar, A., Kapoor, S., Rafiq, K., Chand, H. S., & Jayant, R. D. (2018) · Cardiovascular & Haematological Disorders - Drug Targets · doi:10.2174/1871529x18666180508113253 · Cited by 62 · see citing works

Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy

Lee, P., Zan, B. S., Chen, L.-T., & Chung, T. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s174962 · Cited by 57 · see citing works

Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Left Ventricular Remodeling After Acute Myocardial Infarction by Inhibiting Monocyte-Mediated Inflammation

Mao, Y., Koga, J., Tokutome, M., Matoba, T., Ikeda, G., Nakano, K., & Egashira, K. (2017) · International Heart Journal · doi:10.1536/ihj.16-457 · Cited by 54 · see citing works

Cardiac Regeneration by Statin-Polymer Nanoparticle-Loaded Adipose-Derived Stem Cell Therapy in Myocardial Infarction

Yokoyama, R., Ii, M., Tabata, Y., Hoshiga, M., Ishizaka, N., & Asahi, M. (2019) · Stem Cells Translational Medicine · doi:10.1002/sctm.18-0244 · Cited by 51 · see citing works

Nanomedicines in the treatment of colon cancer: a focus on metallodrugs

Farinha, P. F., Pinho, J. O., Matias, M., & Gaspar, M. M. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00916-7 · Cited by 45 · see citing works

Anti-inflammatory Nanoparticle for Prevention of Atherosclerotic Vascular Diseases

Koga, J., Matoba, T., & Egashira, K. (2016) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.35113 · Cited by 40 · see citing works

Advances in nanobased platforms for cardiovascular diseases: Early diagnosis, imaging, treatment, and tissue engineering

Shariati, L., Esmaeili, Y., Rahimmanesh, I., Babolmorad, S., Ziaei, G., Hasan, A., Boshtam, M., & Makvandi, P. (2023) · Environmental Research · doi:10.1016/j.envres.2023.116933 · Cited by 39 · see citing works

Delivery of Imatinib-Incorporated Nanoparticles into Lungs Suppresses the Development of Monocrotaline-Induced Pulmonary Arterial Hypertension

Akagi, S., Nakamura, K., Miura, D., Saito, Y., Matsubara, H., Ogawa, A., Matoba, T., Egashira, K., & Ito, H. (2015) · International Heart Journal · doi:10.1536/ihj.14-338 · Cited by 38 · see citing works

Intratracheal Administration of Prostacyclin Analogue–incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension

Akagi, S., Nakamura, K., Matsubara, H., Kondo, M., Miura, D., Matoba, T., Egashira, K., & Ito, H. (2016) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000352 · Cited by 36 · see citing works

Neuroprotective potential of cerium oxide nanoparticles for focal cerebral ischemic stroke

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Micromanaging cardiac regeneration: Targeted delivery of microRNAs for cardiac repair and regeneration

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Natural Antioxidants as Potential Therapy, and a Promising Role for Melatonin Against Pulmonary Hypertension

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Current Nanomedicine for Targeted Vascular Disease Treatment: Trends and Perspectives

Choi, K.-A., Kim, J. H., Ryu, K., & Kaushik, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012397 · Cited by 31 · see citing works

Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension

Nakamura, K., Akagi, S., Ejiri, K., Yoshida, M., Miyoshi, T., Toh, N., Nakagawa, K., Takaya, Y., Matsubara, H., & Ito, H. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235885 · Cited by 30 · see citing works

Nanoparticle-Mediated Drug Delivery System for Pulmonary Arterial Hypertension

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Prostacyclin Analogue–Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats

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