Fibroblasts and myofibroblasts in wound healing

Multilineage potential of adult human mesenchymal stem cells

Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052 · see citing works

Cutaneous Wound Healing

Singer, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106 · see citing works

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases: Structure, Function, and Biochemistry

Visse, R., & Nagase, H. (2003) · Circulation Research · doi:10.1161/01.res.0000070112.80711.3d · Cited by 4,575 · see citing works

Fibroblasts in cancer

Kalluri, R., & Zeisberg, M. (2006) · Nature Reviews Cancer · doi:10.1038/nrc1877 · Cited by 4,538 · see citing works

Myofibroblasts and mechano-regulation of connective tissue remodelling

Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290 · see citing works

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., & Janmey, P. A. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20041 · Cited by 2,325 · see citing works

TGF-β signaling and the fibrotic response

Leask, A., & Abraham, D. J. (2004) · The FASEB Journal · doi:10.1096/fj.03-1273rev · Cited by 2,319 · see citing works

Endothelial/Pericyte Interactions

Armulik, A., Abramsson, A., & Betsholtz, C. (2005) · Circulation Research · doi:10.1161/01.res.0000182903.16652.d7 · Cited by 2,048 · see citing works

Formation and function of the myofibroblast during tissue repair

Hinz, B. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700613 · Cited by 1,658 · see citing works

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

Gabbiani, G., Ryan, G. B., & Majno, G. (1971) · Experientia · doi:10.1007/bf02147594 · Cited by 1,485 · see citing works

Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix

Wipff, P.-J., Rifkin, D. B., Meister, J.-J., & Hinz, B. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200704042 · Cited by 1,346 · see citing works

Distinct fibroblast lineages determine dermal architecture in skin development and repair

Driskell, R. R., Lichtenberger, B. M., Hoste, E., Kretzschmar, K., Simons, B. D., Charalambous, M., Ferron, S. R., Herault, Y., Pavlovic, G., Ferguson-Smith, A. C., et al. (2013) · Nature · doi:10.1038/nature12783 · Cited by 1,291 · see citing works

Recent Developments in Myofibroblast Biology

Hinz, B., Phan, S. H., Thannickal, V. J., Prunotto, M., Desmoulière, A., Varga, J., De Wever, O., Mareel, M., & Gabbiani, G. (2012) · The American Journal of Pathology · doi:10.1016/j.ajpath.2012.02.004 · Cited by 1,193 · see citing works

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.

Darby, I. A., Skalli, O., & Gabbiani, G. (1990) · PubMed · Cited by 1,180 · see citing works

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

Desmoulière, A., Redard, M., Darby, I. A., & Gabbiani, G. (1995) · Europe PMC (PubMed Central) · Cited by 1,173 · see citing works

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

Higgins, D. F., Kimura, K., Bernhardt, W. M., Shrimanker, N., Akai, Y., Hohenstein, B., Saito, Y., Johnson, R. S., Kretzler, M., Cohen, C. D., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30487 · Cited by 976 · see citing works

Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites

Abe, R., Donnelly, S. C., Peng, T., Bucala, R., & Metz, C. N. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.12.7556 · Cited by 967 · see citing works

The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1

Serini, G., Bochaton-Piallat, M.-L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L., & Gabbiani, G. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.3.873 · Cited by 847 · see citing works

Stromal myofibroblasts are drivers of invasive cancer growth

De Wever, O., Demetter, P., Mareel, M., & Bracke, M. (2008) · International Journal of Cancer · doi:10.1002/ijc.23925 · Cited by 722 · see citing works

Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers

Goffin, J. M., Pittet, P., Csúcs, G., Lussi, J. W., Meister, J.-J., & Hinz, B. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200506179 · Cited by 703 · see citing works

The myofibroblast: Paradigm for a mechanically active cell

Hinz, B. (2009) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2009.09.020 · Cited by 695 · see citing works

Neuronal Control of Skin Function: The Skin as a Neuroimmunoendocrine Organ

Roosterman, D., Goerge, T., Schneider, S. W., Bunnett, N. W., & Steinhoff, M. S. (2006) · Physiological Reviews · doi:10.1152/physrev.00026.2005 · Cited by 667 · see citing works

Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation

Hinz, B., Mastrangelo, D., Iselin, C. E., Chaponnier, C., & Gabbiani, G. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)61776-2 · Cited by 638 · see citing works

Fibroblast Differentiation in Wound Healing and Fibrosis

Darby, I. A., & Hewitson, T. D. (2007) · International review of cytology · doi:10.1016/s0074-7696(07)57004-x · Cited by 605 · see citing works

Fibroblast heterogeneity: more than skin deep

Sorrell, J. M., & Caplan, A. I. (2004) · Journal of Cell Science · doi:10.1242/jcs.01005 · Cited by 553 · see citing works

The stroma reaction myofibroblast: a key player in the control of tumor cell behavior

Desmoulière, A., Guyot, C., & Gabbiani, G. (2004) · The International Journal of Developmental Biology · doi:10.1387/ijdb.041802ad · Cited by 551 · see citing works

Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis

Aarabi, S., Bhatt, K. A., Shi, Y., Paterno, J., Chang, E. I.-F., Loh, S. A., Holmes, J. W., Longaker, M. T., Yee, H. T., & Gurtner, G. C. (2007) · The FASEB Journal · doi:10.1096/fj.07-8218com · Cited by 516 · see citing works

Integrins and the activation of latent transforming growth factor β1 – An intimate relationship

Wipff, P., & Hinz, B. (2008) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2008.01.012 · Cited by 514 · see citing works

Integrin αVβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1

Annes, J. P., Chen, Y., Munger, J. S., & Rifkin, D. B. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200312172 · Cited by 500 · see citing works

Characterization of SIS3, a Novel Specific Inhibitor of Smad3, and Its Effect on Transforming Growth Factor-β1-Induced Extracellular Matrix Expression

Jinnin, M., Ihn, H., & Tamaki, K. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.017483 · Cited by 446 · see citing works

Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

Kim, K. K., Wei, Y., Szekeres, C. K., Kugler, M. C., Wolters, P. J., Hill, M. L., Frank, J. A., Brumwell, A. N., Wheeler, S. E., Kreidberg, J. A., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36940 · Cited by 399 · see citing works

Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis

Distler, J. H. W., Jüngel, A., Huber, L. C., Schulze‐Horsel, U., Zwerina, J., Gay, R. E., Michel, B. A., Hauser, T., Schett, G., Gay, S., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22314 · Cited by 383 · see citing works

Normal and Pathologic Soft Tissue Remodeling: Role of the Myofibroblast, with Special Emphasis on Liver and Kidney Fibrosis

Desmoulière, A., Darby, I. A., & Gabbiani, G. (2003) · Laboratory Investigation · doi:10.1097/01.lab.0000101911.53973.90 · Cited by 364 · see citing works

Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis.

Iyer, S. N., Gurujeyalakshmi, G., & Giri, S. N. (1999) · PubMed · Cited by 358 · see citing works

Potential cellular and molecular causes of hypertrophic scar formation

van der Veer, W. M., Bloemen, M. C. T., Ulrich, M. M. W., Molema, G., van Zuijlen, P. P. M., Middelkoop, E., & Niessen, F. B. (2008) · Burns · doi:10.1016/j.burns.2008.06.020 · Cited by 356 · see citing works

Stromal Myofibroblasts Predict Disease Recurrence for Colorectal Cancer

辻野, 督., Seshimo, I., Yamamoto, H., Ngan, C. Y., Ezumi, K., Takemasa, I., Ikeda, M., Sekimoto, M., Matsuura∥, N., & Monden, M. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-2191 · Cited by 352 · see citing works

Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors

Dugina, V. B., Fontao, L., Chaponnier, C., Vasiliev, J. M., & Gabbiani, G. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.18.3285 · Cited by 309 · see citing works

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

Puthawala, K., Hadjiangelis, N., Jacoby, S. C., Bayongan, E., Zhao, Z., Yang, Z., Devitt, M. L., Horan, G. S., Weinreb, P. H., Lukashev, M. E., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200706-806oc · Cited by 272 · see citing works

Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts

Wang, J., Chen, H., Seth, A. K., & McCulloch, C. A. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00387.2003 · Cited by 269 · see citing works

Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages

Jahoda, C. A. B., Whitehouse, C. J., Reynolds, A. J., & Hole, N. (2003) · Experimental Dermatology · doi:10.1111/j.0906-6705.2003.00161.x · Cited by 267 · see citing works

Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling

Gabbiani, G., & Hinz, B. (2003) · Thrombosis and Haemostasis · doi:10.1160/th03-05-0328 · Cited by 260 · see citing works

The Single-Molecule Mechanics of the Latent TGF-β1 Complex

Buscemi, L., Ramonet, D., Klingberg, F., Formey, A., Smith-Clerc, J., Meister, J.-J., & Hinz, B. (2011) · Current Biology · doi:10.1016/j.cub.2011.11.037 · Cited by 257 · see citing works

Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and Aging

Mine, S., Fortunel, N. O., Pageon, H., & Asselineau, D. (2008) · PLoS ONE · doi:10.1371/journal.pone.0004066 · Cited by 255 · see citing works

Modulation of Fibroblast Morphology and Adhesion during Collagen Matrix Remodeling

Tamaríz, E., & Grinnell, F. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-05-0291 · Cited by 253 · see citing works

Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells.

van der Loop, F. T. L., Schaart, G., Timmer, E. D. J., Ramaekers, F. C. S., & van Eys, G. J. J. M. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.134.2.401 · Cited by 251 · see citing works

Hair follicle dermal sheath cells: unsung participants in wound healing

Jahoda, C. A. B., & Reynolds, A. J. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06532-1 · Cited by 248 · see citing works

Multiple Organ Engraftment by Bone‐Marrow‐Derived Myofibroblasts and Fibroblasts in Bone‐Marrow‐Transplanted Mice

Direkze, N. C., Forbes, S. J., Brittan, M., Hunt, T., Jeffery, R. E., Preston, S. L., Poulsom, R., Hodivala‐Dilke, K., Alison, M. R., & Wright, N. A. (2003) · Stem Cells · doi:10.1634/stemcells.21-5-514 · Cited by 246 · see citing works

Myofibroblast development is characterized by specific cell-cell adherens junctions

Hinz, B., Pittet, P., Smith-Clerc, J., Chaponnier, C., & Meister, J.-J. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-05-0386 · Cited by 231 · see citing works

Platelet-Derived Growth Factor-β Receptor Activation Is Essential for Fibroblast and Pericyte Recruitment during Cutaneous Wound Healing

Rajkumar, V. S., Shiwen, X., Boström, M., Leoni, P., Muddle, J. R., Ivarsson, M., Gerdin, B., Denton, C. P., Bou–Gharios, G., Black, C. M., et al. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.060196 · Cited by 199 · see citing works

Differences in the Regulation of Fibroblast Contraction of Floating Versus Stressed Collagen Matrices

Grinnell, F., Ho, C.-H., Lin, Y., & Skuta, G. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.2.918 · Cited by 178 · see citing works

Actin cytoskeleton in myofibroblast differentiation: Ultrastructure defining form and driving function

Sandbo, N. K., & Dulin, N. O. (2011) · Translational research · doi:10.1016/j.trsl.2011.05.004 · Cited by 178 · see citing works

Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts

Asano, Y., Ihn, H., Yamane, K., Jinnin, M., & Tamaki, K. (2006) · The American Journal of Pathology · doi:10.2353/ajpath.2006.041306 · Cited by 175 · see citing works

Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives

Hinz, B., & Gabbiani, G. (2010) · F1000 Biology Reports · doi:10.3410/b2-78 · Cited by 172 · see citing works

Identification of fibrocytes in postburn hypertrophic scar

Yang, L., Scott, P. G., Dodd, C. M., Medina, A., Jiao, H., Shankowsky, H. A., Ghahary, A., & Tredget, E. E. (2005) · Wound Repair and Regeneration · doi:10.1111/j.1067-1927.2005.130407.x · Cited by 164 · see citing works

Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation

Kulasekaran, P., Scavone, C. A., Rogers, D. S., Arenberg, D. A., Thannickal, V. J., & Horowitz, J. C. (2009) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0447oc · Cited by 153 · see citing works

The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation

Carracedo, S., Lü, N., Popova, S. N., Jonsson, R., Eckes, B., & Gullberg, D. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.078766 · Cited by 145 · see citing works

Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression

Basu, R. K., Hubchak, S. C., Hayashida, T., Runyan, C. E., Schumacker, P. T., & Schnaper, H. W. (2011) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00335.2010 · Cited by 144 · see citing works

Fibroblast differentiation of bone marrow‐derived cells during wound repair

Opalenik, S. R., & Davidson, J. M. (2005) · The FASEB Journal · doi:10.1096/fj.04-2978fje · Cited by 138 · see citing works

Epithelial–mesenchymal transition in the skin

Nakamura, M., & TOKURA, Y. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2010.11.015 · Cited by 134 · see citing works

Phenotypic Modulation of Intima and Media Smooth Muscle Cells in Fatal Cases of Coronary Artery Lesion

Hao, H., Gabbiani, G., Camenzind, E., Bacchetta, M., Virmani, R., & Bochaton‐Piallat, M. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000199393.74656.4c · Cited by 131 · see citing works

Regulation of myofibroblast activities: Calcium pulls some strings behind the scene

Castella, L. F., Gabbiani, G., McCulloch, C. A., & Hinz, B. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.04.033 · Cited by 123 · see citing works

Thy-1-Integrin αvβ5 Interactions Inhibit Lung Fibroblast Contraction-induced Latent Transforming Growth Factor-β1 Activation and Myofibroblast Differentiation

Zhou, Y., Hagood, J. S., Lu, B., Merryman, W. D., & Murphy-Ullrich, J. E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.126227 · Cited by 118 · see citing works

Correlation between the distribution of smooth muscle or non muscle myosins and α‐smooth muscle actin in normal and pathological soft tissues

Benzonana, G., Skalli, O., & Gabbiani, G. (1988) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.970110405 · Cited by 100 · see citing works

Hypoxia Impairs Skin Myofibroblast Differentiation and Function

Modarressi, A., Pietramaggiori, G., Godbout, C., Vigato, E., Pittet, B., & Hinz, B. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.224 · Cited by 87 · see citing works

The myofibroblast: a study of normal, reactive and neoplastic tissues, with an emphasis on ultrastructure.

Eyden, B. P. (2007) · PubMed · Cited by 77 · see citing works

Role of neurotrophins on dermal fibroblast survival and differentiation

Palazzo, E., Marconi, A., Truzzi, F., Dallaglio, K., Petrachi, T., Humbert, P. G., Schnebert, S., Perrier, É., Dumas, M., & Pincelli, C. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22811 · Cited by 77 · see citing works

Therapeutic Approaches to the Regulation of Wound Angiogenesis

Wietecha, M. S., & DiPietro, L. A. (2013) · Advances in Wound Care · doi:10.1089/wound.2011.0348 · Cited by 76 · see citing works

Differential Contribution of Dermal Resident and Bone Marrow–Derived Cells to Collagen Production during Wound Healing and Fibrogenesis in Mice

Higashiyama, R., Nakao, S., Shibusawa, Y., Ishikawa, O., Moro, T., Mikami, K., Fukumitsu, H., Ueda, Y., Minakawa, K., Tabata, Y., et al. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.314 · Cited by 72 · see citing works

Force-induced Myofibroblast Differentiation through Collagen Receptors Is Dependent on Mammalian Diaphanous (mDia)

Chan, M. W. C., Chaudary, F., Lee, W., Copeland, J. W. R., & McCulloch, C. A. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.075218 · Cited by 60 · see citing works

Redox Signaling as a Therapeutic Target to Inhibit Myofibroblast Activation in Degenerative Fibrotic Disease

Sampson, N., Berger, P., & Zenzmaier, C. (2014) · BioMed Research International · doi:10.1155/2014/131737 · Cited by 54 · see citing works

Inhibition of systemic sclerosis dermal fibroblast type I collagen production and gene expression by simvastatin

Louneva, N., Huaman, G., Fertala, J., & Jiménez, S. A. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21723 · Cited by 49 · see citing works

The myofibroblast: a study of normal, reactive and neoplastic tissues, with an emphasis on ultrastructure. part 2 - tumours and tumour-like lesions.

Eyden, B. (2005) · PubMed · Cited by 48 · see citing works

The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor–beta1

Serini, G., Bochaton-piallat, M.-L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L., & Gabbiani, G. (1998) · Cited by 28 · see citing works

S iah2‐deficient mice show impaired skin wound repair

Musyoka, J. N., Liu, M. C. P., Pouniotis, D. S., Wong, C. S. F., Bowtell, D. D. L., Little, P. J., Getachew, R., Möller, A., & Darby, I. A. (2013) · Wound Repair and Regeneration · doi:10.1111/wrr.12045 · Cited by 7 · see citing works

Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion

Hao, H., Gabbiani, G., Camenzind, E., Bacchetta, M. D., Virmani, R., & Bochaton‐Piallat, M. (2006) · Vascular Pharmacology · doi:10.1016/j.vph.2006.08.294 · Cited by 3 · see citing works

The biology and function of fibroblasts in cancer

Kalluri, R. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2016.73 · Cited by 4,366 · see citing works

Wound Healing: A Cellular Perspective.

Rodrigues, M., Kosaric, N., Bonham, C., & Gurtner, G. (2019) · Physiological Reviews · doi:10.1152/physrev.00067.2017 · Cited by 2,752 · see citing works

Wound healing: cellular mechanisms and pathological outcomes

Wilkinson, H. N., & Hardman, M. J. (2020) · Open Biology · doi:10.1098/rsob.200223 · Cited by 1,886 · see citing works

Immunology of Wound Healing

Ellis, S., Lin, E. J., & Tartar, D. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0234-9 · Cited by 625 · see citing works

Innovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Advancements

Kolimi, P., Narala, S., Nyavanandi, D., Youssef, A. A. A., & Dudhipala, N. R. (2022) · Cells · doi:10.3390/cells11152439 · Cited by 625 · see citing works

Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring

Mascharak, S., desJardins-Park, H. E., Davitt, M. F., Griffin, M., Borrelli, M. R., Moore, A. L., Chen, K., Duoto, B. A., Chinta, M. S., Foster, D. S., et al. (2021) · Science · doi:10.1126/science.aba2374 · Cited by 622 · see citing works

Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases

Hinz, B., & Lagares, D. (2019) · Nature Reviews Rheumatology · doi:10.1038/s41584-019-0324-5 · Cited by 616 · see citing works

Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing

Jahromi, M. A. M., Zangabad, P. S., Basri, S. M. M., Zangabad, K. S., Ghamarypour, A., Aref, A. R., Karimi, M., & Hamblin, M. R. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.08.001 · Cited by 562 · see citing works

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

Dehkordi, A. N., Mirahmadi, F., Chehelgerdi, M., & Dehkordi, S. R. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1212-2 · Cited by 547 · see citing works

Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair

Shook, B. A., Wasko, R. R., Rivera-Gonzalez, G. C., Salazar-Gatzimas, E., López-Giráldez, F., Dash, B. C., Muñoz-Rojas, A. R., Aultman, K. D., Zwick, R. K., Lei, V., et al. (2018) · Science · doi:10.1126/science.aar2971 · Cited by 519 · see citing works

Scleral hypoxia is a target for myopia control

Wu, H., Chen, W., Zhao, F., Zhou, Q., Reinach, P. S., Deng, L., Ma, L., Luo, S., Srinivasalu, N., Pan, M., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1721443115 · Cited by 507 · see citing works

Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment

Liu, T., Zhou, L., Li, D., Andl, T., & Zhang, Y. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00060 · Cited by 446 · see citing works

Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing

Shiekh, P. A., Singh, A., & Kumar, A. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120020 · Cited by 443 · see citing works

Scaffolds for Wound Healing Applications

Neguț, I., Dorcioman, G., & Grumezescu, V. (2020) · Polymers · doi:10.3390/polym12092010 · Cited by 426 · see citing works

Anti-oxidant electroactive and antibacterial nanofibrous wound dressings based on poly(ε-caprolactone)/quaternized chitosan-graft-polyaniline for full-thickness skin wound healing

He, J., Liang, Y., Shi, M., & Guo, B. (2019) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.123464 · Cited by 423 · see citing works

Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis

Shu, D. Y., & Lovicu, F. J. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.08.001 · Cited by 391 · see citing works

Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts

Ziani, L., Chouaı̈b, S., & Thiery, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00414 · Cited by 379 · see citing works

Role of fibroblasts in wound healing and tissue remodeling on Earth and in space

Cialdai, F., Risaliti, C., & Monici, M. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.958381 · Cited by 373 · see citing works

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

Wang, L., Hu, L., Zhou, X., Xiong, Z., Zhang, C., Shehada, H. M. A., Hu, B., Song, J., & Chen, L. (2017) · Scientific Reports · doi:10.1038/s41598-017-12919-x · Cited by 369 · see citing works

Cancer-associated fibroblasts and their influence on tumor immunity and immunotherapy

Barrett, R. L., & Puré, E. (2020) · eLife · doi:10.7554/elife.57243 · Cited by 351 · see citing works

The role of photobiomodulation on gene expression of cell adhesion molecules in diabetic wounded fibroblasts in vitro

Ayuk, S. M., Abrahamse, H., & Houreld, N. N. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.05.027 · Cited by 346 · see citing works

Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways

Yoshida, G. J. (2020) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01611-0 · Cited by 321 · see citing works

Smart Bandages: The Future of Wound Care

Derakhshandeh, H., Kashaf, S. S., Aghabaglou, F., Ghanavati, I., & Tamayol, A. (2018) · Trends in biotechnology · doi:10.1016/j.tibtech.2018.07.007 · Cited by 320 · see citing works

Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing

Casado‐Díaz, A., Quesada‐Gómez, J. M., & Dorado, G. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00146 · Cited by 320 · see citing works

Fibronectin in development and wound healing

Patten, J., & Wang, K. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.09.005 · Cited by 303 · see citing works

TGF ‐β as a driver of fibrosis: physiological roles and therapeutic opportunities

Budi, E. H., Schaub, J. R., Decaris, M. L., Turner, S., & Derynck, R. (2021) · The Journal of Pathology · doi:10.1002/path.5680 · Cited by 300 · see citing works

C-Reactive Protein and Cancer—Diagnostic and Therapeutic Insights

Hart, P. C., Rajab, I. M., Alebraheem, M., & Potempa, L. A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.595835 · Cited by 285 · see citing works

The Functional Role of Extracellular Matrix Proteins in Cancer

Popova, N. V., & Jücker, M. (2022) · Cancers · doi:10.3390/cancers14010238 · Cited by 277 · see citing works

ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion

Chronopoulos, A., Robinson, B. K., Sarper, M., Cortés, E., Auernheimer, V., Lachowski, D., Attwood, S. J., García, R., Ghassemi, S., Fabry, B., et al. (2016) · Nature Communications · doi:10.1038/ncomms12630 · Cited by 275 · see citing works

The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis

Kolb, P. S., Ayaub, E. A., Zhou, W., Yum, V., Dickhout, J. G., & Ask, K. (2015) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2015.01.015 · Cited by 271 · see citing works

Oral wound healing models and emerging regenerative therapies

Toma, A. I., Fuller, J. M., Willett, N. J., & Goudy, S. L. (2021) · Translational research · doi:10.1016/j.trsl.2021.06.003 · Cited by 254 · see citing works

The cellular basis of fibrotic tendon healing: challenges and opportunities

Nichols, A. E. C., Best, K. T., & Loiselle, A. E. (2019) · Translational research · doi:10.1016/j.trsl.2019.02.002 · Cited by 244 · see citing works

Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases

Huang, J., Heng, S., Zhang, W., Liu, Y., Xia, T., Ji, C., & Zhang, L.-J. (2022) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2022.02.027 · Cited by 238 · see citing works

Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing

Qiang, L., Yang, S., Cui, Y., & He, Y. (2020) · Autophagy · doi:10.1080/15548627.2020.1816342 · Cited by 237 · see citing works

The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets

Nguyen, J. K., Austin, E., Huang, A., Mamalis, A., & Jagdeo, J. R. (2019) · Archives of Dermatological Research · doi:10.1007/s00403-019-01972-3 · Cited by 234 · see citing works

Bioglass Activated Skin Tissue Engineering Constructs for Wound Healing

Yu, H., Peng, J., Xu, Y., Chang, J., & Li, H. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b09853 · Cited by 231 · see citing works

In-situ crosslinked hydrogel based on amidated pectin/oxidized chitosan as potential wound dressing for skin repairing

Amirian, J., Zeng, Y., Shekh, M. I., Sharma, G., Stadler, F. J., Song, J., Du, B., & Zhu, Y. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117005 · Cited by 224 · see citing works

Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy

Gupta, S., Roy, A., & Dwarakanath, B. S. R. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00068 · Cited by 218 · see citing works

Instructive microenvironments in skin wound healing: Biomaterials as signal releasing platforms

Castaño, Ó., Pérez‐Amodio, S., Navarro‐Requena, C., Mateos‐Timoneda, M. A., & Engel, E. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.03.012 · Cited by 216 · see citing works

A Systematic Review on Classification, Identification, and Healing Process of Burn Wound Healing

Abazari, M., Ghaffari, A., Rashidzadeh, H., Badeleh, S. M., & Maleki, Y. (2020) · The International Journal of Lower Extremity Wounds · doi:10.1177/1534734620924857 · Cited by 216 · see citing works

Bioadhesives for internal medical applications: A review

Zhu, W., Chuah, Y. J., & Wang, D. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.034 · Cited by 213 · see citing works

Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D

Jiang, S., Lyu, C., Zhao, P., Li, W., Kong, W., Huang, C., Genin, G. M., & Du, Y. (2019) · Nature Communications · doi:10.1038/s41467-019-11397-1 · Cited by 210 · see citing works

The tension biology of wound healing

Harn, H. I., Ogawa, R., Hsu, C., Hughes, M. W., Tang, M., & Chuong, C. (2017) · Experimental Dermatology · doi:10.1111/exd.13460 · Cited by 208 · see citing works

Development of a bacterial cellulose-based hydrogel cell carrier containing keratinocytes and fibroblasts for full-thickness wound healing

Loh, E. Y. X., Mohamad, N., Fauzi, M. B., Ng, M. H., Ng, S. F., & Amin, M. C. I. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-21174-7 · Cited by 208 · see citing works

Targeting the renin-angiotensin-aldosterone system in fibrosis

Alqudah, M., Hale, T. M., & Czubryt, M. P. (2020) · Matrix Biology · doi:10.1016/j.matbio.2020.04.005 · Cited by 202 · see citing works

Dermal fibroblast in cutaneous development and healing

Thulabandu, V., Chen, D.-M., & Atit, R. (2017) · Wiley Interdisciplinary Reviews: Developmental Biology · doi:10.1002/wdev.307 · Cited by 194 · see citing works

Cancer-associated fibroblasts: Origin, function, imaging, and therapeutic targeting

Rimal, R., Desai, P. B., Daware, R., Hosseinnejad, A., Prakash, J., Lammers, T., & Singh, S. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114504 · Cited by 201 · see citing works

Advanced strategies to thwart foreign body response to implantable devices

Capuani, S., Malgir, G., Chua, C. Y. X., & Grattoni, A. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10300 · Cited by 200 · see citing works

Grapefruit-derived extracellular vesicles as a promising cell-free therapeutic tool for wound healing

Savcı, Y., Kırbaş, O. K., Bozkurt, B. T., Abdik, E. A., Taşlı, P. N., Şahi̇n, F., & Abdik, H. (2021) · Food & Function · doi:10.1039/d0fo02953j · Cited by 195 · see citing works

A Comprehensive Review of Natural Compounds for Wound Healing: Targeting Bioactivity Perspective

Trinh, T. X., Long, N. V., Anh, L. T. V., Nga, P. T., Giang, N. N., Chien, P. N., Nam, S., & Heo, C. Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179573 · Cited by 193 · see citing works

Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges

Trace, A. P., Enos, C., Mantel, A., & Harvey, V. M. (2016) · American Journal of Clinical Dermatology · doi:10.1007/s40257-016-0175-7 · Cited by 189 · see citing works

Naturally-derived electrospun wound dressings for target delivery of bio-active agents

Fahimirad, S., & Ajalloueian, F. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.05.053 · Cited by 189 · see citing works

Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice

Zhang, Z., Shao, M., Hepler, C., Zi, Z., Zhao, S., An, Y., Zhu, Y., Ghaben, A. L., Wang, M.-Y., Li, N., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci130239 · Cited by 185 · see citing works

Silk Fibroin Biomaterials and Their Beneficial Role in Skin Wound Healing

Mazurek, Ł., Szudzik, M., Rybka, M., & Konop, M. (2022) · Biomolecules · doi:10.3390/biom12121852 · Cited by 185 · see citing works

Development and use of biomaterials as wound healing therapies

Murray, R. Z., West, Z. E., Cowin, A. J., & Farrugia, B. L. (2019) · Burns & Trauma · doi:10.1186/s41038-018-0139-7 · Cited by 183 · see citing works

Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue

Sinha, M., Sen, C., Singh, K., Das, A., Ghatak, S., Rhea, B., Blackstone, B., Powell, H., Khanna, S., & Roy, S. (2018) · Nature Communications · doi:10.1038/s41467-018-03208-w · Cited by 164 · see citing works

An Updated Review of Hypertrophic Scarring

Mony, M. P., Harmon, K. A., Hess, R., Dorafshar, A. H., & Shafikhani, S. H. (2023) · Cells · doi:10.3390/cells12050678 · Cited by 174 · see citing works

Functional electrospun fibers for the treatment of human skin wounds

Wang, J., & Windbergs, M. (2017) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2017.07.001 · Cited by 173 · see citing works

Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1

He, J., Fang, B., Shan, S., Xie, Y., Wang, C., Zhang, Y., Zhang, X., & Li, Q. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03481-6 · Cited by 172 · see citing works

Topical gel-based biomaterials for the treatment of diabetic foot ulcers

Bardill, J. R., Laughter, M. R., Stager, M. A., Liechty, K. W., Krebs, M. D., & Zgheib, C. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.10.045 · Cited by 168 · see citing works

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis

Waters, D. W., Blokland, K. E. C., Pathinayake, P. S., Burgess, J. K., Mutsaers, S. E., Prêle, C. M., Schuliga, M. J., Grainge, C., & Knight, D. A. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00037.2018 · Cited by 167 · see citing works

Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

Jiang, T., Wang, Z., & Sun, J. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01723-6 · Cited by 167 · see citing works

FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?

Dendl, K., Koerber, S. A., Kratochwil, C., Cardinale, J., Finck, R., Dabir, M., Novruzov, E., Watabe, T., Kramer, V., Choyke, P. L., et al. (2021) · Cancers · doi:10.3390/cancers13194946 · Cited by 163 · see citing works

Epithelial–mesenchymal transition in tissue repair and degeneration

Youssef, K. K., & Nieto, M. A. (2024) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-024-00733-z · Cited by 162 · see citing works

Nano-formulated curcumin accelerates acute wound healing through Dkk-1-mediated fibroblast mobilization and MCP-1-mediated anti-inflammation

Dai, X., Liu, J., Zheng, H., Wichmann, J., Hopfner, Ú., Sudhop, S., Prein, C., Shen, Y., Machens, H.-G., & Schilling, A. F. (2017) · NPG Asia Materials · doi:10.1038/am.2017.31 · Cited by 161 · see citing works

Wound Healing Effect of Kaempferol in Diabetic and Nondiabetic Rats

Özay, Y., Güzel, S., Yumrutaş, Ö., Pehlivanoğlu, B., Erdoğdu, İ. H., Yildirim, Z., Türk, B. A., & Darcan, S. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2018.08.009 · Cited by 158 · see citing works

Corneal injury: Clinical and molecular aspects

Barrientez, B., Nicholas, S. E., Whelchel, A. E., Sharif, R., Hjortdal, J., & Karamichos, D. (2019) · Experimental Eye Research · doi:10.1016/j.exer.2019.107709 · Cited by 156 · see citing works

Role of the Skin Immune System in Wound Healing

Cioce, A., Cavani, A., Cattani, C., & Scopelliti, F. (2024) · Cells · doi:10.3390/cells13070624 · Cited by 154 · see citing works

Microneedle arrays for the treatment of chronic wounds

Barnum, L., Samandari, M., Schmidt, T. A., & Tamayol, A. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2020.1819787 · Cited by 152 · see citing works

Curcumin accelerates cutaneous wound healing via multiple biological actions: The involvement of TNF‐α, MMP‐9, α‐SMA, and collagen

Yen, Y., Pu, C., Liu, C., Chen, Y., Chen, Y., Liang, C., Hsieh, J., Huang, H., & Chen, Y. (2018) · International Wound Journal · doi:10.1111/iwj.12904 · Cited by 150 · see citing works

Chemically Modified Gellan Gum Hydrogels with Tunable Properties for Use as Tissue Engineering Scaffolds

Xu, Z., Li, Z., Jiang, S., & Bratlie, K. M. (2018) · ACS Omega · doi:10.1021/acsomega.8b00683 · Cited by 150 · see citing works

Beta‐caryophyllene as an antioxidant, anti‐inflammatory and re‐epithelialization activities in a rat skin wound excision model

Gushiken, L. F. S., Beserra, F. P., Hussni, M. F., Gonzaga, M. T., Ribeiro, V. P., de Souza, P. F., Campos, J. C. L., Massaro, T. N. C., Hussni, C. A., Takahira, R. K., et al. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/9004014 · Cited by 150 · see citing works

Development of reduced graphene oxide (rGO)-isabgol nanocomposite dressings for enhanced vascularization and accelerated wound healing in normal and diabetic rats

Ponrasu, T., Kannan, R., Ramachandran, B., Ganeshkumar, M., Suguna, L., & Muthuvijayan, V. (2018) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2018.01.110 · Cited by 147 · see citing works

Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies

Lurje, I., Gaisa, N. T., Weiskirchen, R., & Tacke, F. (2023) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2023.101191 · Cited by 147 · see citing works

The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited

Dzobo, K., Senthebane, D. A., & Dandara, C. (2023) · Cancers · doi:10.3390/cancers15020376 · Cited by 146 · see citing works

Human acellular amniotic membrane incorporating exosomes from adipose-derived mesenchymal stem cells promotes diabetic wound healing

Xiao, S., Xiao, C., Miao, Y., Wang, J., Chen, R., Fan, Z., & Hu, Z. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02333-6 · Cited by 145 · see citing works

Polyurethane/carboxymethylcellulose nanofibers containing Malva sylvestris extract for healing diabetic wounds: Preparation, characterization, in vitro and in vivo studies

Almasian, A., Najafi, F., Eftekhari, M., Ardekani, M. R. S., Sharifzadeh, M. S., & Khanavi, M. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111039 · Cited by 139 · see citing works

Single-Cell RNA-Sequencing Reveals Lineage-Specific Regulatory Changes of Fibroblasts and Vascular Endothelial Cells in Keloids

Liu, X., Chen, W., Zeng, Q., Ma, B., Li, Z., Meng, T., Chen, J., Yu, N., Zhou, Z., & Long, X. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.06.010 · Cited by 137 · see citing works

Biocompatibility Pathways: Biomaterials-Induced Sterile Inflammation, Mechanotransduction, and Principles of Biocompatibility Control

Williams, D. F. (2016) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.6b00607 · Cited by 135 · see citing works

Emerging Innovative Wound Dressings

Aljghami, M. E., Saboor, S., & Amini‐Nik, S. (2018) · Annals of Biomedical Engineering · doi:10.1007/s10439-018-02186-w · Cited by 135 · see citing works

Fibroblasts in the Tumor Microenvironment

Truffi, M., Sorrentino, L., & Corsi, F. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-37184-5_2 · Cited by 134 · see citing works

Fetal Dermal Mesenchymal Stem Cell-Derived Exosomes Accelerate Cutaneous Wound Healing by Activating Notch Signaling

Wang, X., Jiao, Y., Pan, Y., Zhang, L., Gong, H., Qi, Y., Wang, M., Gong, H., Shao, M., Wang, X., et al. (2019) · Stem Cells International · doi:10.1155/2019/2402916 · Cited by 133 · see citing works

Update on management of keloid and hypertrophic scars: A systemic review

Elsaie, M. L. (2021) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.14310 · Cited by 128 · see citing works

Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies

Yoshida, G. J., Azuma, A., Miura, Y., & Orimo, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092256 · Cited by 127 · see citing works

PEG grafted chitosan scaffold for dual growth factor delivery for enhanced wound healing

Vijayan, A., Sabareeswaran, A., & Kumar, G. S. V. (2019) · Scientific Reports · doi:10.1038/s41598-019-55214-7 · Cited by 127 · see citing works

In vivo evaluation of bacterial cellulose/acrylic acid wound dressing hydrogel containing keratinocytes and fibroblasts for burn wounds

Mohamad, N., Loh, E. Y. X., Fauzi, M. B., Ng, M. H., & Amin, M. C. I. M. (2018) · Drug Delivery and Translational Research · doi:10.1007/s13346-017-0475-3 · Cited by 126 · see citing works

Quercetin promotes cutaneous wound healing in mice through Wnt/β-catenin signaling pathway

Mi, Y., Zhong, L., Lu, S., Hu, P., Pan, Y., Ma, X., Yan, B., Wei, Z., & Yang, G. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115066 · Cited by 126 · see citing works

Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review

Xu, F.-W., Lv, Y.-L., Zhong, Y., Xue, Y., Wang, Y., Zhang, L., Hu, X. M., & Tan, W. (2021) · Molecules · doi:10.3390/molecules26206123 · Cited by 123 · see citing works

Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at All Wound Healing Stages (Inflammation, Proliferation and Maturation)

Čoma, M., Fröhlichová, L., Urban, L., Zajíček, R., Urban, T., Szabó, P., Novak, S., Fetissov, V., Dvořánková, B., Smetana, K., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020897 · Cited by 121 · see citing works

The Role of the Lysyl Oxidases in Tissue Repair and Remodeling: A Concise Review

Cai, L., Xiong, X., Kong, X., & Xie, J. (2017) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-016-0007-0 · Cited by 120 · see citing works

Cellular Signalling and Photobiomodulation in Chronic Wound Repair

Leyane, T. S., Jere, S. W., & Houreld, N. N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011223 · Cited by 120 · see citing works

Cancer-associated fibroblasts: key determinants of tumor immunity and immunotherapy

Barrett, R., & Puré, E. (2020) · Current Opinion in Immunology · doi:10.1016/j.coi.2020.03.004 · Cited by 117 · see citing works

A biomechanical perspective on stress fiber structure and function

Kassianidou, E., & Kumar, S. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.04.006 · Cited by 114 · see citing works

Evaluating polymeric biomaterials to improve next generation wound dressing design

Hodge, J., Zamierowski, D. S., Robinson, J. L., & Mellott, A. J. (2022) · Biomaterials Research · doi:10.1186/s40824-022-00291-5 · Cited by 113 · see citing works

Exosomes derived from human amniotic epithelial cells accelerate diabetic wound healing via PI3K-AKT-mTOR-mediated promotion in angiogenesis and fibroblast function

Pei, W., Zhong, C., Yang, X., Shu, F., Xiao, S., Gong, T., Luo, P., Li, L., Chen, Z., Zheng, Y., et al. (2020) · Burns & Trauma · doi:10.1093/burnst/tkaa020 · Cited by 111 · see citing works

Role of Fibroblasts and Myofibroblasts on the Pathogenesis and Treatment of Pelvic Organ Prolapse

Güler, Z., & Roovers, J. (2022) · Biomolecules · doi:10.3390/biom12010094 · Cited by 111 · see citing works

Differential contribution of pancreatic fibroblast subsets to the pancreatic cancer stroma

Garcia, P. E., Adoumie, M., Kim, E. C., Zhang, Y., Scales, M. K., El-Tawil, Y. S., Shaikh, A. Z., Wen, H.-J., Bednar, F., Allen, B. L., et al. (2020) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.05.004 · Cited by 110 · see citing works

Collagen extract obtained from Nile tilapia (Oreochromis niloticus L.) skin accelerates wound healing in rat model via up regulating VEGF, bFGF, and α-SMA genes expression

Elbialy, Z. I., Atiba, A. S., Abdelnaby, A., Al‐Hawary, I. I., Elsheshtawy, A., El‐Serehy, H. A., Abdel‐Daim, M. M., Fadl, S. E., & Assar, D. H. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-02566-2 · Cited by 110 · see citing works

The Spectrum of Scarring in Craniofacial Wound Repair

desJardins-Park, H. E., Mascharak, S., Chinta, M. S., Wan, D. C., & Longaker, M. T. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00322 · Cited by 108 · see citing works

Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance

Zhou, X., Ni, Y., Liang, X., Lin, Y., An, B., He, X., & Zhao, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.915094 · Cited by 108 · see citing works

The complex dialogue between (myo)fibroblasts and the extracellular matrix during skin repair processes and ageing

Vedrenne, N., Coulomb, B., Danigo, A., Bonté, F., & Desmoulière, A. (2012) · Pathologie Biologie · doi:10.1016/j.patbio.2011.10.002 · Cited by 89 · see citing works

Scar Formation: Cellular Mechanisms

Darby, I. A., & Desmoulière, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-44766-3_3 · Cited by 35 · see citing works

The Role of Myofibroblasts in Physiological and Pathological Tissue Repair

Schuster, R., Younesi, F., Ezzo, M., & Hinz, B. (2023) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041231 · Cited by 232 · see citing works

A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin

Sawant, M., Hinz, B., Schönborn, K., Zeinert, I., Eckes, B., Krieg, T., & Schuster, R. (2021) · Wound Repair and Regeneration · doi:10.1111/wrr.12950 · Cited by 34 · see citing works

Mechanisms of pathological scarring: Role of myofibroblasts and current developments

Sarrazy, V., Billet, F., Micallef, L., Coulomb, B., & Desmoulière, A. (2011) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2011.00708.x · Cited by 288 · see citing works