Scientific Opinion on the safety of caffeine

EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)·2015·EFSA Journal

Cites (309)

Items 201–296 of 296

  1. Effects of caffeine on alcohol-related changes in behavioural control and perceived intoxication in light caffeine consumers
    Angela Suzanne Attwood, Peter J. Rogers, Alia F. Ataya, Sally H. Adams, Marcus Robert Munafo · 2011 · Psychopharmacology
  2. CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking
    Eline M. Rodenburg, Mark Eijgelsheim, Johanna Marianne Geleijnse, Najaf Amin, Cornelia M. van Duijn, Albert Hofman D, André Gerardus Uitterlinden, Bruno H. Ch. Stricker, Loes E. Visser · 2012 · American Journal of Clinical Nutrition
  3. A 60 day double-blind, placebo-controlled safety study involving Citrus aurantium (bitter orange) extract
    Gilbert R. Kaats, Howard B. Miller, Harry G. Preuss, Sidney J. Stohs · 2013 · Food and Chemical Toxicology
  4. Chronic Effects of Habitual Caffeine Consumption on Laboratory and Ambulatory Blood Pressure Levels
    James, J. E. · 1994 · European Journal of Cardiovascular Prevention & Rehabilitation
  5. Interaction of Caffeine With Regadenoson-Induced Hyperemic Myocardial Blood Flow as Measured by Positron Emission Tomography
    Gaemperli, Oliver, Schepis, Tiziano, Koepfli, Pascal, Siegrist, Patrick T., Fleischman, Samuel, Nguyen, Patricia, Olmsted, Ann, Wang, Whedy, Lieu, Hsiao, Kaufmann, Philipp A. · 2008 · Journal of the American College of Cardiology
  6. Coffee Consumption and Coronary Heart Disease in Middle‐aged Swedish Men
    Wilhelmsen, Lars, Tibblin, Gösta, Elmfeldt, Dag, Wedel, Hans, Werkö, Lars · 1977 · Acta Medica Scandinavica
  7. Hydration during Exercise in Warm, Humid Conditions: Effect of a Caffeinated Sports Drink
    Mindy L. Millard-Stafford, Kirk J. Cureton, Jonathan E. Wingo, Jennifer Trilk, Gordon L. Warren, Maxime E. Buyckx · 2007 · International Journal of Sport Nutrition and Exercise Metabolism
  8. Acute Effect of Black and Green Tea on Aortic Stiffness and Wave Reflections
    Vlachopoulos, Charalambos, Alexopoulos, Nikolaos, Dima, Ioanna, Aznaouridis, Konstantinos, Andreadou, Ioanna, Stefanadis, Christodoulos · 2006 · Journal of the American College of Nutrition
  9. Cardiovascular, behavioral, and subjective effects of caffeine under field conditions
    Ilse Höfer, K. Bättig · 1994 · Pharmacology Biochemistry and Behavior
  10. Phenotype Refinement Strengthens the Association of AHR and CYP1A1 Genotype with Caffeine Consumption
    McMahon, George, Taylor, Amy E., Davey Smith, George, Munafò, Marcus R. · 2014 · PLoS ONE
  11. Caffeine and Blood Pressure Response: Sex, Age, and Hormonal Status
    Noha H. Farag, Thomas L. Whitsett, Barbara S. McKey, Michael F. Wilson, Andrea S. Vincent, Susan A. Everson‐Rose, William R. Lovallo · 2010 · Journal of Women s Health
  12. Caffeine disposition in obesity.
    DR Abernethy, E L Todd, Janice B. Schwartz · 1985 · British Journal of Clinical Pharmacology
  13. Impact of coffee and other selected factors on general mortality and mortality due to cardiovascular disease in Croatia.
    Anamarija Jazbec, Diana Šimić, Naima Čorović, Zijad Duraković, Mladen Pavlović · 2003 · PubMed
  14. Association between coffee consumption and risk of hypertension
    Paolo Palatini, Francesca Dorigatti, Massimo Santonastaso, Susanna Cozzio, Tiziano Biasion, Guido Garavelli, Achille Cesare Pessina, Lucio Mos · 2007 · Annals of Medicine
  15. Caffeine Impairs Myocardial Blood Flow Response to Physical Exercise in Patients with Coronary Artery Disease as well as in Age-Matched Controls
    Namdar, Mehdi, Schepis, Tiziano, Koepfli, Pascal, Gaemperli, Oliver, Siegrist, Patrick T., Grathwohl, Renate, Valenta, Ines, Delaloye, Raphael, Klainguti, Michael, Wyss, Christophe A. et al. · 2009 · PLoS ONE
  16. Coffee intake and coronary heart disease
    Klag, Michael J., Mead, Lucy A., Lacroix, Andrea Z., Wang, Nae-Yuh, Coresh, Josef, Liang, Kung-Yee, Pearson, Thomas A., Levine, David M. · 1994 · Annals of Epidemiology
  17. Caffeine Metabolism and the Risk of Spontaneous Abortion of Normal Karyotype Fetuses
    L. B. Signorello, Anna Nordmark, Fredrik Granath, William J. Blot, Joseph K. McLaughlin, Göran Annerén, Stefan Lundgren, Anders Ekbom, Anders Rane, Sven Cnattingius · 2001 · Obstetrics and Gynecology
  18. Untitled work
    2004 · PubMed
  19. Effects of mixing alcohol with caffeinated beverages on subjective intoxication: A systematic review and meta-analysis
    Sarah Benson, Joris C. Verster, Chris Alford, Andrew B Scholey · 2014 · Neuroscience & Biobehavioral Reviews
  20. Dose‐response effects of intravenous caffeine in normal volunteers
    P. V. Nickell, Thomas W. Uhde · 1994 · Anxiety
  21. Coffee consumption and risk of heart failure in men: An analysis from the Cohort of Swedish Men
    Hanna N. Ahmed, Emily B. Levitan, Alicja Wolk, Murray A. Mittleman · 2009 · American Heart Journal
  22. Coffee Consumption and Risk of Myocardial Infarction among Older Swedish Women
    Sarah R. Preis, Agneta Åkesson, Meir J. Stampfer, A. Wolk · 2006 · American Journal of Epidemiology
  23. A randomized study on coffee and blood pressure.
    Bak Aa, D E Grobbee · 1990 · PubMed
  24. Caffeine restriction: effect on mild hypertension.
    MacDonald, T M, Sharpe, K, Fowler, G, Lyons, D, Freestone, S, Lovell, H G, Webster, J, Petrie, J C · 1991 · BMJ
  25. Coffee consumption and risk of ischaemic heart disease — a settled issue?
    GYNTELBERG, F., HEIN, H. O., SUADICANI, P., SØRENSEN, H. · 1995 · Journal of Internal Medicine
  26. Acute behavioral and cardiac effects of alcohol and caffeine, alone and in combination, in humans
    Craig R. Rush, Stephen T. Higgins, J. R. Hughes, Warren Kurt Bickel, M. S. Wiegner · 1993 · Behavioural Pharmacology
  27. Biochemical Mechanism of Caffeine Tolerance
    Hermann P. T. Ammon · 1991 · Archiv der Pharmazie
  28. Hemodynamic Mechanisms Underlying the Incomplete Tolerance to Caffeine's Pressor Effects
    Farag, Noha H., Vincent, Andrea S., McKey, Barbara S., Whitsett, Thomas L., Lovallo, William R. · 2005 · The American Journal of Cardiology
  29. Coffee consumption is not related to the metabolic syndrome at the age of 36 years: the Amsterdam Growth and Health Longitudinal Study
    Maurice T. Driessen, Lando L. J. Koppes, L Veldhuis, David Samoocha, Jos W. R. Twisk · 2008 · European Journal of Clinical Nutrition
  30. Metabolic and physiological effects of ingesting extracts of bitter orange, green tea and guarana at rest and during treadmill walking in overweight males
    Craig Sale, Roger C. Harris, Simon K. Delves, Jo Corbett · 2006 · International Journal of Obesity
  31. Coffee consumption and cause-specific mortality association with age at death and compression of mortality
    Lindsted, Kristian D., Kuzma, Jan W., Anderson, James L. · 1992 · Journal of Clinical Epidemiology
  32. Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans
    John G. Seifert, Aaron Nelson, Julia A. Devonish, Edmund R. Burke, Sidney J. Stohs · 2011 · International Journal of Medical Sciences
  33. Effect of Coffee Intake on Blood Pressure in Male Habitual Alcohol Drinkers
    Kazuo Funatsu, Takeshi Yamashita, Haruo Nakamura · 2005 · Hypertension Research
  34. CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies
    Hongge Wang, Zhi Zhang, Sugui Han, Yujuan Lu, Fumin Feng, Juxiang Yuan · 2012 · BMC Cancer
  35. Energy Drinks: An Assessment of the Potential Health Risks in the Canadian Context
    Joel B. Rotstein, Jennifer Barber, Carl Strowbridge, Stephen Hayward, Rong Huang, Samuel Benrejeb Godefroy · 2013 · International Food Risk Analysis Journal
  36. Behavioral and Autonomic Effects of Caffeine in Normal Boys
    Judith L. Rapoport, Robert Elkins, Alan Neims, Theodore P. Zahn, Carol J. Berg · 2017 · Developmental Pharmacology and Therapeutics
  37. Scientific Opinion on the substantiation of health claims related to caffeine and increased fat oxidation leading to a reduction in body fat mass (ID 735, 1484), increased energy expenditure leading to a reduction in body weight (ID 1487), increased alertness (ID 736, 1101, 1187, 1485, 1491, 2063, 2103) and increased attention (ID 736, 1485, 1491, 2375) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · 2011 · EFSA Journal
  38. Long‐term alcohol and caffeine intake and risk of sudden cardiac death in women
    Bertoia, Monica L, Triche, Elizabeth W, Michaud, Dominique S, Baylin, Ana, Hogan, Joseph W, Neuhouser, Marian L, Freiberg, Matthew S, Allison, Matthew A, Safford, Monika M, Li, Wenjun et al. · 2013 · The American Journal of Clinical Nutrition
  39. Coffee, blood pressure and plasma lipids: a randomized controlled trial.
    M L Burr, John Gallacher, Barbara K. Butland, C. Bolton, Leonie G. Downs · 1989 · PubMed
  40. Effect of caffeine on SPECT myocardial perfusion imaging during regadenoson pharmacologic stress: a prospective, randomized, multicenter study
    Tejani, Furqan H., Thompson, Randall C., Kristy, Rita, Bukofzer, Stan · 2014 · The International Journal of Cardiovascular Imaging
  41. Relationship of blood pressure, heart rate and behavioral mood state to norepinephrine kinetics in younger and older men following caffeine ingestion
    Paul Joseph Arciero, AW Gardner, Neal L. Benowitz, Éric T. Poehlman · 1998 · European Journal of Clinical Nutrition
  42. Boiled coffee and blood pressure. A 14-week controlled trial.
    Marc Dusseldorp, Paul Smits, Jacques W.M. Lenders, Theo A. Thien, Mira Katan · 1991 · Hypertension
  43. Relationship of blood pressure, behavioral mood state, and physical activity following caffeine ingestion in younger and older women
    Paul Joseph Arciero, Michael J. Ormsbee · 2009 · Applied Physiology, Nutrition, and Metabolism
  44. Lifestyle- and occupation-related changes in blood pressure over a six-year period in a cohort of working men
    David A. Jenner, Ian B. Puddey, Lawrence Joseph Beilin, Robert Vandongen · 1988 · Journal of Hypertension
  45. Mortality patterns among hypertensives by reported level of caffeine consumption
    Martin, Jeanne B., Annegers, J.Fred, Curb, J.David, Heyden, Siegfried, Howson, Christopher, Lee, Eun Sul, Lee, Marshall · 1988 · Preventive Medicine
  46. Rate of Caffeine Metabolism and Risk of Spontaneous Abortion
    Laura Fenster, Christopher M. Quale, Robert A. Hiatt, M. Wilson, Gayle C. Windham, Neal L. Benowitz · 1998 · American Journal of Epidemiology
  47. Effect of coffee on ambulatory blood pressure in patients with treated hypertension
    Robert Eggertsen, Åke Andreasson, Thomas Hedner, B. E. Karlberg, L. Hansson · 1993 · Journal of Internal Medicine
  48. Marginal effects of a large caffeine dose on heat balance during exercise‐heat stress
    Ely, Brett R., Ely, Matthew R., Cheuvront, Samuel N. · 2011 · International Journal of Sport Nutrition and Exercise Metabolism
  49. Caffeine dependence in schoolchildren?
    Avram Goldstein M. D, Margaret E. Wallace · 1997 · Experimental and Clinical Psychopharmacology
  50. Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors
    Lena Aronsen, Elin Øien Ørvoll, Roy A. Lysaa, Aina Westrheim Ravna, Georg Sager · 2014 · European Journal of Pharmacology
  51. Total body water and its compartments are not affected by ingesting a moderate dose of caffeine in healthy young adult males
    Silva, Analiza M., Júdice, Pedro B., Matias, Catarina N., Santos, Diana A., Magalhães, João P., St-Onge, Marie-Pierre, Gonçalves, Ezequiel M., Armada-da-Silva, Paulo, Sardinha, Luís B. · 2013 · Applied Physiology, Nutrition, and Metabolism
  52. Coffee consumption and the risk of heart failure in Finnish men and women
    Yujie Wang, Jaakko Tuomilehto, Pekka Jousilahti, Riitta Antikaínen, Markku Mähönen, Satu Männistö, Peter Todd Katzmarzyk, Gang Hu · 2010 · Heart
  53. Caffeine self-administration and subjective effects in adolescents.
    Kelly L. Hale, John R. Hughes, Alison H. Oliveto, Stephen T. Higgins · 1995 · Experimental and Clinical Psychopharmacology
  54. Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot & humid climate.
    Wong Chee Ping, Chen Chee Keong, Amit Bandyopadhyay · 2010 · PubMed
  55. Caffeine, blood pressure, and serum lipids
    Annette A. A. Bak, Diederick E. Grobbee · 1991 · American Journal of Clinical Nutrition
  56. Effects of cessation of caffeinated-coffee consumption on ambulatory and resting blood pressure in men
    H. Robert Superko, Jeff Myll, Connie DiRicco, Paul T. Williams, Walter M. Bortz, Peter D. Wood · 1994 · The American Journal of Cardiology
  57. Scientific Opinion on the substantiation of health claims related to caffeine and increase in physical performance during short‐term high‐intensity exercise (ID 737, 1486, 1489), increase in endurance performance (ID 737, 1486), increase in endurance capacity (ID 1488) and reduction in the rated perceived exertion/effort during exercise (ID 1488, 1490) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · 2011 · EFSA Journal
  58. Caffeine-Induced Changes in Cardiovascular Function during Resistance Training
    Astorino, Todd Anthony, Rohmann, Riana Lee, Firth, Kelli, Kelly, Sondra · 2007 · International Journal of Sport Nutrition and Exercise Metabolism
  59. EFFECTS OF CAFFEINE ON CLASSROOM BEHAVIOR, SUSTAINED ATTENTION, AND A MEMORY TASK IN PRESCHOOL CHILDREN
    Ruth A. Baer · 1987 · Journal of Applied Behavior Analysis
  60. Determination of the caffeine contents of various food items within the Austrian market and validation of a caffeine assessment tool (CAT)
    E. Rudolph, A Faerbinger, Jürgen S. König · 2012 · Food Additives & Contaminants Part A
  61. Caffeine Tolerance is Incomplete: Persistent Blood Pressure Responses in the Ambulatory Setting
    FARAG, N, VINCENT, A, SUNG, B, WHITSETT, T, WILSON, M, LOVALLO, W · 2005 · American Journal of Hypertension
  62. Intake of caffeine and other methylxanthines during pregnancy and risk for adverse effects in pregnant women and their foetuses
    2005 · TemaNord
  63. Absence of QTc‐Interval–Prolonging or Hemodynamic Effects of a Single Dose of Bitter‐Orange Extract in Healthy Subjects
    Bokyung Min, Deborah A. Cios, Jeffrey Kluger, Charles Michael White · 2005 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
  64. Caffeine intake and small‐for‐gestational‐age birth: modifying effects of xenobiotic‐metabolising genes and smoking
    Claire Infante‐Rivard · 2007 · Paediatric and Perinatal Epidemiology
  65. Acute autonomic nervous system effects of caffeine in prepubertal boys
    Theodore P. Zahn, Judith L. Rapoport · 1987 · Psychopharmacology
  66. Risk assessment of caffeine among children and adolescents in the Nordic countries
    Jan Alexander, Kirsi H. Liukkonen, Marta Axelstad, Helena Hallström, Elisabeth Elind, Helle Margrete Meltzer, Elisabeth Jona Solbergsdottir, Henrik Rye Lam, Tor Øystein Fotland · 2008 · TemaNord
  67. Behavioral Correlates of Caffeine Consumption by Children
    Alan Leviton · 1992 · Clinical Pediatrics
  68. Acute effects of coffee on QT interval in healthy subjects
    Silvio Buscemi, Alessandro Mattina, Maria Rosaria Tranchina, Salvatore Verga · 2011 · Nutrition Journal
  69. Caffeine dependence in schoolchildren?
    Avram Goldstein, Margaret E. Wallace · 1997 · Experimental and Clinical Psychopharmacology
  70. Coffee consumption and blood pressure
    Phillip C. Rosmarin, William B. Applegate, Grant W. Somes · 1990 · Journal of General Internal Medicine
  71. Coffee consumption and coronary heart disease mortality in Scottish men: a 21 year follow up study.
    Hart, C, Smith, G D · 1997 · Journal of Epidemiology and Community Health
  72. Caffeine exposure in children and adolescents consuming ready‐to‐drink coffee products
    Waizenegger, Julia, Castriglia, Silvio, Winkler, Gertrud, Schneider, Rüdiger, Ruge, Winfried, Kersting, Mathilde, Alexy, Ute, Lachenmeier, Dirk W. · 2011 · Journal of Caffeine Research
  73. Caffeine increases sweating sensitivity via changes in sudomotor activity during physical loading
    Kim, Tae-Wook, Shin, Young-Oh, Lee, Jeong-Beom, Min, Young-Ki, Yang, Hun-Mo · 2011 · Journal of Medicinal Food
  74. Greater Coffee Intake in Men Is Associated With Steeper Age-Related Increases in Blood Pressure
    Paul P. Giggey, Carrington R. Wendell, Alan B. Zonderman, Shari R. Waldstein · 2010 · American Journal of Hypertension
  75. Coffee Consumption and Incidence of Heart Failure in Women
    Emily B. Levitan, Hanna N. Ahmed, Murray A. Mittleman, Alicja Wolk · 2011 · Circulation Heart Failure
  76. Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome
    Shayesteh Jahanfar, Sharifah Halimah Jaafar · 2013 · Cochrane Database of Systematic Reviews
  77. UK Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) Symposium: Potential implications of obesity on persistent organic pollutant kinetics and possible ramifications for risk assessment
    Lauren Kent, Claire Potter, David Michael Gott · 2015 · Toxicology Letters
  78. Caffeine Ingestion and Intense Resistance Training Minimize Postexercise Hypotension in Normotensive and Prehypertensive Men
    Astorino, Todd Anthony, Martin, Brian J., Schachtsiek, Lena, Wong, Keau · 2013 · Research in Sports Medicine
  79. Acute effects of caffeine and tobacco on arterial function and wave travel
    Janice Swampillai, Fabian Rakebrandt, Keith Morris, C. J. H. Jones, Alan G. Fraser · 2006 · European Journal of Clinical Investigation
  80. The Relationship of Coffee Consumption to Various Self-Reported Cardiovascular Events in Middle-Aged Norwegian Men and Women
    Inger Stensvold, Aage Tverdal · 1995 · Scandinavian Journal of Social Medicine
  81. Childhood Caffeine Tic Syndrome
    Richard E. Davis, Ivan Osorio · 1998 · PEDIATRICS
  82. Acute Effect of Caffeine Intake on Hemodynamics after Resistance Exercise in Young Non-Hypertensive Subjects
    Souza, Diego, Casonatto, Juliano, Poton, Roberto, Willardson, Jeffrey, Polito, Marcos · 2014 · Research in Sports Medicine
  83. Association of cytochrome P450 1B1 polymorphism with first-trimester miscarriage
    Anna-Helena Karypidis, Torbjörn Söderström, Anna Nordmark · 2006 · Fertility and Sterility
  84. Lack of pharmacological active saliva levels of caffeine in breast-fed infants.
    R Hildebrandt, Ursula Gundert‐Remy · 1983 · PubMed
  85. The assessment of vascular function during dietary intervention trials in human subjects
    McCall, Damian O., McKinley, Michelle C., Noad, Rebecca, McKeown, Pascal P., McCance, David R., Young, Ian S., Woodside, Jayne V. · 2011 · British Journal Of Nutrition
  86. The Effect of Coffee and Quantity of Consumption on Specific Cardiovascular and All-Cause Mortality
    Rohit Seth Loomba, Saurabh Aggarwal, Rohit Romesh Arora · 2014 · American Journal of Therapeutics
  87. Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome
    Shayesteh Jahanfar, Sharifah Halimah Jaafar · 2009 · Cochrane Database of Systematic Reviews
  88. Guidelines for nutrition therapy in critical illness: are not they all the same?
    Robert G. Martindale, Mary S. McCarthy, Stephen A. McClave · 2011 · PubMed
  89. Does Nausea and Vomiting of Pregnancy Play a Role in the Association Found Between Maternal Caffeine Intake and Fetal Growth Restriction?
    Sinead M. Boylan, Darren Charles Greenwood, Nisreen A Alwan, Marcus S. Cooke, V. A. Dolby, Alastair W M Hay, Sara Kirk, Justin C. Konje, Neelam Potdar, Susan Shires et al. · 2012 · Maternal and Child Health Journal
  90. Extensive literature search as preparatory work for the safety assessment for caffeine
    Sarah Bull, Terry Brown, Karin Burnett, Lini Ashdown, Lesley Rushton · 2015 · EFSA Supporting Publications
  91. Coffee Consumption and the Incidence of Coronary Heart Disease
    1987 · New England Journal of Medicine
  92. Caffeine Metabolism and the Risk of Spontaneous Abortion of Normal Karyotype Fetuses
    Lisa B. Signorello, Anna Nordmark, Fredrik N. Granath · 2001 · Obstetrics and Gynecology
  93. Coffee Intake and Risk of Hypertension: The Johns Hopkins Precursors Study
    Klag, Michael J., Wang, Nae-Yuh, Meoni, Lucy A., Brancati, Frederick L., Cooper, Lisa A., Liang, Kung-Yee, Young, J. Hunter, Ford, Daniel E. · 2002 · Archives of Internal Medicine
  94. Cambios en la presión arterial en un grupo de voluntarios normotensos después del consumo de diferentes dosis de café filtrado
    Gloria María Agudelo, Claudia Velásquez, Olga L. Cardona, Mauricio Duque, Myriam Posada, Vanesa Pineda S, Leonor Eugenia Suárez Flórez · 2008 · Institutional Repository University of Antioquia (University of Antioquia)
  95. Genetic Modifiers of Caffeine Consumption and Risk of Myocardial Infarction
    Laura Anne Da Costa · 2011 · TSpace (University of Toronto)
  96. Changes in blood pressure in a group of normotense volunteers after consumption or different doses of filtered coffee
    Gloria María Agudelo, Claudia Velásquez, Olga L. Cardona, Mauricio Duque, Myriam Posada, Vanesa Pineda S, Leonor Eugenia Suárez Flórez · 2008 · Revista Colombiana de Cardiología