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Improving the self-management of chronic pain: COping with persistent Pain, Effectiveness Research in Self-management (COPERS)
Open accessAbstract
Background: Chronic musculoskeletal pain is a common problem that is difficult to treat. Self-management support interventions may help people to manage this condition better; however, there is limited evidence showing that they improve clinical outcomes. Our overarching research question was ‘Does a self-management support programme improve outcomes for people living with chronic musculoskeletal pain?’. Aim: To develop, evaluate and test the clinical effectiveness and cost-effectiveness of a theoretically grounded self-management support intervention for people living with chronic musculoskeletal pain. Methods: In phase 1 we carried out two systematic reviews to synthesise the evidence base for self-management course content and delivery styles likely to help those with chronic pain. We also considered the psychological theories that might underpin behaviour change and pain management principles. Informed by these data we developed the Coping with persistent Pain, Evaluation Research in Self-management (COPERS) intervention, a group intervention delivered over 3 days with a top-up session after 2 weeks. It was led by two trained facilitators: a health-care professional and a layperson with experience of chronic pain. To ensure that we measured the most appropriate outcomes we reviewed the literature on potential outcome domains and measures and consulted widely with patients, tutors and experts. In a feasibility study we demonstrated that we could deliver the COPERS intervention in English and, to increase the generalisability of our findings, also in Sylheti for the Bangladeshi community. In phase 2 we ran a randomised controlled trial to test the clinical effectiveness and cost-effectiveness of adding the COPERS intervention to a best usual care package (usual care plus a relaxation CD and a pain toolkit leaflet). We recruited adults with chronic musculoskeletal pain largely from primary care and musculoskeletal physiotherapy services in two localities: east London and Coventry/Warwickshire. We collected follow-up data at 12 weeks (self-efficacy only) and 6 and 12 months. Our primary outcome was pain-related disability (Chronic Pain Grade disability subscale) at 12 months. We also measured costs, health utility (European Quality of Life-5 Dimensions), anxiety, depression [Hospital Anxiety and Depression Scale (HADS)], coping, pain acceptance and social integration. Data on the use of NHS services by participants were extracted from NHS electronic records. Results: We recruited 703 participants with a mean age of 60 years (range 19–94 years); 81% were white and 67% were female. Depression and anxiety symptoms were common, with mean HADS depression and anxiety scores of 7.4 [standard deviation (SD) 4.1] and 9.2 (SD 4.6), respectively. Intervention participants received 85% of the course content. At 12 months there was no difference between treatment groups in our primary outcome of pain-related disability [difference –1.0 intervention vs. control, 95% confidence interval (CI) –4.9 to 3.0]. However, self-efficacy, anxiety, depression, pain acceptance and social integration all improved more in the intervention group at 6 months. At 1 year these differences remained for depression (–0.7, 95% CI –1.2 to –0.2) and social integration (0.8, 95% CI, 0.4 to 1.2). The COPERS intervention had a high probability (87%) of being cost-effective compared with usual care at a threshold of £30,000 per quality-adjusted life-year. Conclusions: Although the COPERS intervention did not affect our primary outcome of pain-related disability, it improved psychological well-being and is likely to be cost-effective according to current National Institute for Health and Care Excellence criteria. The COPERS intervention could be used as a substitute for less well-evidenced (and more expensive) pain self-management programmes. Effective interventions to improve hard outcomes in chronic pain patients, such as disability, are still needed. Trial registration: Current Controlled Trials ISRCTN22714229. Funding: The project was funded by the National Institute for Health Research Programme Grants for Applied Research programme and will be published in full in Programme Grants for Applied Research ; Vol. 4, No. 14. See the NIHR Journals Library website for further project information.
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“Our previous experience is that the challenges of running non-English language group interventions for chronic painful disorders are too great to do successfully within an RCT.22”
From Usual care and a self-management support programme versus usual care and a relaxation programme for people living with chronic headache disorders: A randomised controlled trial protocol (CHESS) (2020) · cites this paper as [22]
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“HADs has been used in many previous studies of chronic pain, including the COPERS (Coping with persistent Pain, Effectiveness Research into Self-management) study where we identified positive effects on both anxiety and depression in a chronic pain population.22 34”
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“5) 0, 0 Male 98 (33) 132 (33) 0, 0 Lives alone 101 (34) 143 (36) 4, 6 Ethnicity White 239 (80) 325 (81) 0, 0 Black 36 (12) 53 (13) Asian 20 (7) 13 (3) Mixed 5 (2) 9 (2) Other 0 (0) 3 (1) Self-rated English language fluency Fluent 259 (86) 341 (85) 0, 0 Good 36 (12) 56 (14) Below average 3 (1) 6 (1) Poor 2 (1) 0 (0) Ag…”
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“Characteristic Sylheti speaking (N= 26), n (%) English speaking (N= 48), n (%) Employment Employed 1 (4) 13 (27) Family/home keeper 8 (31) 5 (10) Retired 1 (4) 8 (17) Unable to work because of ill health 4 (15) 17 (35) Unemployed 3 (12) 5 (10) Missing 9 (35) 0 (0) Education None 3 (12) 1 (2) Until < 12 years 4 (15) 0…”
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BackgroundEarly management of persistent non-specific low back pain: summary of NICE guidance
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“Response Baseline, n (%) 6 months, n (%) 12 months, n (%) Control Intervention Control Intervention Control Intervention Very good 17 (6) 27 (7) 11 (5) 20 (6) 8 (3) 14 (4) Good 100 (33) 138 (34) 81 (34) 121 (35) 84 (34) 130 (38) Fair 130 (43) 159 (39) 100 (42) 144 (42) 115 (47) 144 (42) Bad 45 (15) 63 (16) 39 (16) 46…”
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Cognitive–behavioral treatment of insomnia secondary to chronic pain.
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“Exposure London, n (%) Warwick, n (%) Both, n (%) Adherent (≥ 17 sessions) 115 (63) 167 (76) 282 (70) Moderate adherence (9–16 sessions) 16 (9) 10 (5) 26 (6) Non-adherent (≤ 8 sessions) 52 (28) 43 (20) 95 (24) Total 183 (100) 220 (100) 403 (100) Complier (≥ 12 sessions) 130 (71) 175 (80) 305 (76) Non-complier (≤ 11 se…”
InfluentialCognitive-behavioral treatment of insomnia secondary to chronic pain.
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Self-management education programmes for osteoarthritis
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“5) 0, 0 Male 98 (33) 132 (33) 0, 0 Lives alone 101 (34) 143 (36) 4, 6 Ethnicity White 239 (80) 325 (81) 0, 0 Black 36 (12) 53 (13) Asian 20 (7) 13 (3) Mixed 5 (2) 9 (2) Other 0 (0) 3 (1) Self-rated English language fluency Fluent 259 (86) 341 (85) 0, 0 Good 36 (12) 56 (14) Below average 3 (1) 6 (1) Poor 2 (1) 0 (0) Ag…”
BackgroundInfluentialFear avoidance and prognosis in back pain: A systematic review and synthesis of current evidence
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“W20 Community centre Physiotherapist and lay person 9 6 (67) 69”
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Life stress, social support, and psychological vulnerability: Epidemiological considerations
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“Participants Number contacted Total number booked on a course (% of those contacted) Attendance at day 1 (% of those approached/booked) English-speaking females 228 30 (13) 23 (77) English-speaking males 134 26 (19) 19 (73) Sylheti-speaking females 115 34 (30) 22 (65) Sylheti-speaking males 46 7 (15) 4 (57) FEASIBILIT…”
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“Response Baseline, n (%) 6 months, n (%) 12 months, n (%) Control Intervention Control Intervention Control Intervention Very good 17 (6) 27 (7) 11 (5) 20 (6) 8 (3) 14 (4) Good 100 (33) 138 (34) 81 (34) 121 (35) 84 (34) 130 (38) Fair 130 (43) 159 (39) 100 (42) 144 (42) 115 (47) 144 (42) Bad 45 (15) 63 (16) 39 (16) 46…”
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Psychological therapies for the management of chronic pain (excluding headache) in adults
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“Characteristic Sylheti speaking (N= 26), n (%) English speaking (N= 48), n (%) Employment Employed 1 (4) 13 (27) Family/home keeper 8 (31) 5 (10) Retired 1 (4) 8 (17) Unable to work because of ill health 4 (15) 17 (35) Unemployed 3 (12) 5 (10) Missing 9 (35) 0 (0) Education None 3 (12) 1 (2) Until < 12 years 4 (15) 0…”
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Predicting satisfaction with social support from social network structure
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How effective are expert patient (lay led) education programmes for chronic disease?
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Controlled trial of Internet-based treatment with telephone support for chronic back pain
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“Service Baseline, n (%) 6-month follow-up, n (%) 12-month follow-up, n (%) Intervention Control Intervention Control Intervention Control Consultations NA NA 370 (92) 276 (92) 370 (92) 276 (92) Prescriptions 332 (82) 229 (76) 350 (87) 258 (86) 350 (87) 258 (86) Investigations NA NA 370 (92) 276 (92) 370 (92) 276 (92)…”
Coping with chronic pain: a comparison of two measures
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“Parameter Complete data set Imputed data set Intervention, mean (SD) Control, mean (SD) Intervention, mean (SD) Control, mean (SD) Baseline prescription cost (£) 154 (252) 176 (253) 148 (273) 161 (257) Baseline EQ-5D score 0.”
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Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management
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“W07 Community centre Physiotherapist and lay person 10 9 (90) 93”
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“0) Male 215 (33) 15 (29) Living alone 218 (33) 26 (51) Ethnicity White 523 (80) 41 (80) Black 83 (13) 6 (12) Asian 30 (5) 3 (6) Mixed or other 16 (2) 1 (2) Fluent in or good at English 642 (98) 50 (98) Age at which formal education ended ≤ 12 years 6 (1) 0 (0) 13–19 years 472 (72) 37 (73) ≥ 20 years or still in full-t…”
Social support and health-related quality of life in chronic heart failure patients
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The NHS outcomes framework 2012-3
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Active Exercise, Education, and Cognitive Behavioral Therapy for Persistent Disabling Low Back Pain
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“Characteristic Sylheti speaking (N= 26), n (%) English speaking (N= 48), n (%) Employment Employed 1 (4) 13 (27) Family/home keeper 8 (31) 5 (10) Retired 1 (4) 8 (17) Unable to work because of ill health 4 (15) 17 (35) Unemployed 3 (12) 5 (10) Missing 9 (35) 0 (0) Education None 3 (12) 1 (2) Until < 12 years 4 (15) 0…”
Research in Community and Mental Health
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A 3-year follow-up of a multidisciplinary rehabilitation programme for back and neck pain
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Behavioural treatment for chronic low-back pain
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Expert patients usher in a new era of opportunity for the NHS
Donaldson, L. (2003) · BMJ · doi:10.1136/bmj.326.7402.1279 · Cited by 182 · cited 7×
“Unemployed and looking for work 10 (3) 20 (5) Still in full-time education 3 (1) 1 (< 1) Unable to work because of long-term sickness 62 (21) 86 (21) Looking after home/family 14 (5) 23 (6) Retired from paid work 132 (44) 175 (43) Other 1 (< 1) 7 (2) Time kept from usual activities because of pain in the past 6 months…”
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Self-management education programmes for osteoarthritis
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Digital Support Interventions for the Self-Management of Low Back Pain: A Systematic Review
Nicholl, B. I., Sandal, L. F., Stochkendahl, M. J., McCallum, M., Suresh, N., Vasseljen, O., Hartvigsen, J., Mork, P. J., Kjær, P., Søgaard, K., et al. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7290 · Cited by 190
“In addition, these reviews have suggested that future studies should extend the outcomes of interest to include aspects of self-efficacy, and also consider the impact of the duration of the intervention [13,40], increase the length of follow-up [16], and also consider the impact of such interventions on health care ut…”
BackgroundElbers, S., Wittink, H. M., Pool, J. J. M., & Smeets, R. (2018) · European Journal of Pain · doi:10.1002/ejp.1253 · Cited by 92
Ashaye, T., Hounsome, N., Carnes, D., Taylor, S. J., Homer, K., Eldridge, S. M., Spencer, A. E., Rahman, A., Foell, J., & Underwood, M. R. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019491 · Cited by 77
“The demography of the study participants was: 67% female, mean age 60 years (52 years in London and 67 in Midlands) and 81% white British.”
InfluentialSelf-citationKongsted, A., Ris, I., Kjær, P., Vach, W., Morsø, L., & Hartvigsen, J. (2019) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-019-2443-1 · Cited by 57
On behalf of the CHESS team, Patel, S., Potter, R. C., Matharu, M. S., Carnes, D., Taylor, S. J., Nichols, V. P., Pincus, T., Underwood, M. R., & Sandhu, H. K. (2019) · The Journal of Headache and Pain · doi:10.1186/s10194-019-0980-5 · Cited by 37
“With the associated links between chronic headaches and those with chronic pain, we have drawn upon the knowledge and experience of intervention design and delivery from those involved in the design and running of the COPERS study [37].”
BackgroundInfluentialSelf-citation
Metadata
- Authors
- Taylor, S. J., Carnes, D., Homer, K., Pincus, T., Kahan, B. C., Hounsome, N., Eldridge, S., Spencer, A., Diaz-Ordaz, K., Rahman, A., Mars, T. S., Foell, J., Griffiths, C. J., & Underwood, M. R.
- Affiliations
- Queen Mary University of London (GB)
- Royal Holloway University of London (GB)
- University of Exeter (GB)
- Department of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK
- University College Hospital (GB)
- University of Warwick (GB)
- Corresponding author
- Taylor, Stephanie JC
- ORCID
- Venue
- Programme Grants for Applied Research
- Published
- 2016-09
- Volume
- 4
- Issue
- 14
- Pages
- 1-440
- ISSN
- 2050-4322 (ISSN-L)
- 2050-4330
- OpenAlex
- W2521165122
- Cited by
- 44
- References
- 352
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 5 · 2023: 7 · 2022: 1 · 2021: 6 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 3
- FWCI
- 4.05
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Programme Grants for Applied Research (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- Sussex Research Online (University of Sussex) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Figshare (submittedVersion)
- Open Research Exeter (University of Exeter) (submittedVersion)
- Funders
- National Institute for Health Research (RP-PG-0707-10189)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Keywords
- chronic musculoskeletal pain, self-management support, group intervention, pain-related disability, cost-effectiveness, pain acceptance, coping, anxiety and depression, self-efficacy, Bangladeshi community, primary care, physiotherapy, health care utilization, behaviour change theory, EQ-5D
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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