Cited by 219Immune responses and vaccinationsImmune Response and InflammationT-cell and B-cell Immunology

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The Role of Environmental Factors in Modulating Immune Responses in Early Life

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MacGillivray, Duncan M., Kollmann, Tobias R.·2014·Frontiers in Immunology

DOI 10.3389/fimmu.2014.00434PMC PMC4161944

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Abstract

The concept of immunological memory stipulates that past exposures shape present immune function. These exposures include not only specific antigens impacting adaptive immune memory but also conserved pathogen or danger associated molecular patterns that mold innate immune responses for prolonged periods of time. It should thus not come as a surprise that there is a vast range of external or environmental factors that impact immunity. The importance of environmental factors modulating immunity is most readily recognized in early life, a period of rapidly changing environments. We here summarize available data on the role of environment shaping immune development and from it derive an overarching hypothesis relating the underlying molecular mechanisms and evolutionary principles involved.

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An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Hay fever, hygiene, and household size.
Strachan, D. P. (1989) · BMJ · doi:10.1136/bmj.299.6710.1259 · Cited by 5,054
The gut microbiota shapes intestinal immune responses during health and disease
Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029
Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N., & Knight, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002601107 · Cited by 4,774
Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science · doi:10.1126/science.1241214 · Cited by 3,788
Inflammatory Mechanisms in Obesity
Gregor, M. F., & Hotamisligil, G. S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101322 · Cited by 3,754
Epigenetic modifications and human disease
Portela, A., & Esteller, M. (2010) · Nature Biotechnology · doi:10.1038/nbt.1685 · Cited by 2,938
Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism
Munn, D. H., Zhou, M., Attwood, J. T., Bondarev, I. E., Conway, S. J., Marshall, B., Brown, C. C., & Mellor, A. L. (1998) · Science · doi:10.1126/science.281.5380.1191 · Cited by 2,589
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
Orkin, S. H., & Zon, L. I. (2008) · Cell · doi:10.1016/j.cell.2008.01.025 · Cited by 2,570
Intrauterine infection and preterm delivery
Goldenberg, R. L., Hauth, J. C., & Andrews, W. W. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005183422007 · Cited by 2,548
Environmental epigenomics and disease susceptibility
Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2045 · Cited by 2,492
Trained Immunity: A Memory for Innate Host Defense
Netea, M. G., Quintin, J., & van der Meer, J. W. M. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.04.006 · Cited by 1,760
Breastfeeding and Maternal and Infant Health Outcomes In Developed Countries
(2007) · AAP Grand Rounds · doi:10.1542/gr.18-2-15 · Cited by 1,556
Unravelling the effects of the environment and host genotype on the gut microbiome
Spor, A., Koren, O., & Ley, R. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2540 · Cited by 1,509
Breastfeeding and maternal and infant health outcomes in developed countries.
Ip, S., Chung, M. C., Raman, G., Chew, P., Magula, N. P., DeVine, D., Trikalinos, T. A., & Lau, J. (2007) · PubMed Central · Cited by 1,416
Variation in protection by BCG: implications of and for heterologous immunity
Fine, P. (1995) · The Lancet · doi:10.1016/s0140-6736(95)92348-9 · Cited by 1,385
Innate immunity of the newborn: basic mechanisms and clinical correlates
Levy, O. (2007) · Nature reviews. Immunology · doi:10.1038/nri2075 · Cited by 1,227
Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor
Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., et al. (2013) · Science · doi:10.1126/science.1229000 · Cited by 1,173
The Dutch Famine and Its Long-Term Consequences for Adult Health
Roseboom, T., de Rooij, S., & Painter, R. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.07.001 · Cited by 1,137
Developmental Origins of Health and Disease: Brief History of the Approach and Current Focus on Epigenetic Mechanisms
Wadhwa, P. D., Buß, C., Entringer, S., & Swanson, J. (2009) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1237424 · Cited by 1,045
Protection by BCG vaccine against tuberculosis: a systematic review of randomized controlled trials
Mangtani, P., Abubakar, I., Ariti, C., Beynon, R., Pimpin, L., Fine, P. E. M., Rodrigues, L. C., Smith, P. G., Lipman, M., Whiting, P. F., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/cit790 · Cited by 995
Discovery of Human Zinc Deficiency: Its Impact on Human Health and Disease
Prasad, A. S. (2013) · Advances in Nutrition · doi:10.3945/an.112.003210 · Cited by 919
Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
Kaati, G., Bygren, L., & Edvinsson, S. (2002) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200859 · Cited by 896
Nutritional and physiologic significance of human milk proteins
Lönnerdal, B. L. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.6.1537s · Cited by 879
Pregnancy and Infection
Kourtis, A. P., Read, J. S., & Jamieson, D. J. (2014) · New England Journal of Medicine · doi:10.1056/nejmra1213566 · Cited by 850
The human milk microbiota: Origin and potential roles in health and disease
Fernández, L., Langa, S., Martín, V., Maldonado‐Barragán, A., Jiménez, E., Martı́n, R., & Rodríguez, J. M. (2012) · Pharmacological Research · doi:10.1016/j.phrs.2012.09.001 · Cited by 849
Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease
Greenblum, S., Turnbaugh, P. J., & Borenstein, E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116053109 · Cited by 821
Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds
Grandjean, P., Andersen, E. W., Budtz-Jørgensen, E., Nielsen, F., Mølbak, K., Weihe, P., & Heilmann, C. (2012) · JAMA · doi:10.1001/jama.2011.2034 · Cited by 809
Developmental origins of non-communicable disease: Implications for research and public health
Barouki, R., Gluckman, P. D., Grandjean, P., Hanson, M. A., & Heindel, J. J. (2012) · Environmental Health · doi:10.1186/1476-069x-11-42 · Cited by 788
Prenatal exposure to the Dutch famine and disease in later life: An overview
Painter, R. C., Roseboom, T. J., & Bleker, O. P. (2005) · Reproductive Toxicology · doi:10.1016/j.reprotox.2005.04.005 · Cited by 784
Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis
Robinson, D. P., & Klein, S. L. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.02.023 · Cited by 745
‘ Everything is everywhere , but, the environment selects ’; what did Baas Becking and Beijerinck really say?
de Wit, R., & Bouvier, T. C. (2006) · Environmental Microbiology · doi:10.1111/j.1462-2920.2006.01017.x · Cited by 730
Isolation of Commensal Bacteria from Umbilical Cord Blood of Healthy Neonates Born by Cesarean Section
Jiménez, E., Fernández, L., Marín, M. L., Martı́n, R., Odriozola, J. M., Nueno‐Palop, C., Narbad, A., Olivares, M. M., Xaus, J., & Rodríguez, J. M. (2005) · Current Microbiology · doi:10.1007/s00284-005-0020-3 · Cited by 681
Interactions Between Gut Microbiota and Host Metabolism Predisposing to Obesity and Diabetes
Musso, G., Gambino, R., & Cassader, M. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-012510-175505 · Cited by 598
Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly
Kollmann, T. R., Levy, O., Montgomery, R. R., & Goriely, S. (2012) · Immunity · doi:10.1016/j.immuni.2012.10.014 · Cited by 591
Self-citation
Mother's little helpers: mechanisms of maternal-fetal tolerance
Trowsdale, J., & Betz, A. G. (2006) · Nature Immunology · doi:10.1038/ni1317 · Cited by 588
Mercury Exposure and Children's Health
Böse‐O’Reilly, S., McCarty, K. M., Steckling, N., & Lettmeier, B. (2010) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2010.07.002 · Cited by 577
The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease
Sze, M. A., Dimitriu, P. A., Hayashi, S., Elliott, W. M., McDonough, J. E., Gosselink, J. V., Cooper, J. D., Sin, D. D., Mohn, W. W., & Hogg, J. C. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201111-2075oc · Cited by 569
Lymphoid Potential, Probed before Circulation in Mouse, Is Restricted to Caudal Intraembryonic Splanchnopleura
Cumano, A., Dieterlen‐Lièvre, F., & Godin, I. (1996) · Cell · doi:10.1016/s0092-8674(00)80166-x · Cited by 567
The Immunological Components of Human Milk and Their Effect on Immune Development in Infants ,
Field, C. J. (2005) · Journal of Nutrition · doi:10.1093/jn/135.1.1 · Cited by 557
Cesarean Versus Vaginal Delivery: Long-term Infant Outcomes and the Hygiene Hypothesis
Neu, J., & Rushing, J. (2011) · Clinics in Perinatology · doi:10.1016/j.clp.2011.03.008 · Cited by 548
HLA‐G and immune tolerance in pregnancy
Hunt, J. S., Petroff, M. G., McIntire, R. H., & Ober, C. (2005) · The FASEB Journal · doi:10.1096/fj.04-2078rev · Cited by 533
Disease activity of rheumatoid arthritis during pregnancy: Results from a nationwide prospective study
de Man, Y. A., Dolhain, R. J. E. M., van de Geijn, F. E., Willemsen, S. P., & Hazes, J. M. W. (2008) · Arthritis Care & Research · doi:10.1002/art.24003 · Cited by 527
Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis
Lü, K., Abo, R., Schlieper, K. A., Graffam, M. E., Levine, S. S., Wishnok, J. S., Swenberg, J. A., Tannenbaum, S. R., & Fox, J. G. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307429 · Cited by 527
Beyond stem cells: self-renewal of differentiated macrophages
Sieweke, M. H., & Allen, J. E. (2013) · Science · doi:10.1126/science.1242974 · Cited by 503
Transgenerational effects of prenatal exposure to the 1944–45 Dutch famine
Veenendaal, M., Painter, R., de Rooij, Sr., Bossuyt, P., van der Post, J., Gluckman, P., Hanson, M., & Roseboom, T. (2013) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.12136 · Cited by 477
Reprogramming of the immune system during zinc deficiency
Fraker, P. J., & King, L. E. (2004) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.24.012003.132454 · Cited by 470
Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults
Kollmann, T. R., Crabtree, J., Rein‐Weston, A., Blimkie, D., Thommai, F., Wang, X. Y., Lavoie, P. M., Furlong, J., Fortuno, E. S., Hajjar, A. M., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901481 · Cited by 465
Self-citation
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
Bruniquel, D., & Schwartz, R. H. (2003) · Nature Immunology · doi:10.1038/ni887 · Cited by 460
Health effects of passive smoking
Chinn, S., Rona, R. J., Cook, D. G., Strachan, D. P., & Carey, I. M. (1999) · Thorax · doi:10.1136/thx.54.5.468a · Cited by 445
Partition of Environmental Chemicals between Maternal and Fetal Blood and Tissues
Needham, L. L., Grandjean, P., Heinzow, B., Jørgensen, P. J., Nielsen, F., Patterson, D. G., Sjödin, A., Turner, W. E., & Weihe, P. (2010) · Environmental Science & Technology · doi:10.1021/es1019614 · Cited by 406
Chronic helminth infections induce immunomodulation: Consequences and mechanisms
van Riet, E., Hartgers, F. C., & Yazdanbakhsh, M. (2007) · Immunobiology · doi:10.1016/j.imbio.2007.03.009 · Cited by 395
Immunologic Effects of Background Exposure to Polychlorinated Biphenyls and Dioxins in Dutch Preschool Children
Weisglas‐Kuperus, N., Patandin, S., Berbers, G. A. M., Sas, T., Mulder, P. G. H., Sauer, P. J. J., & Hooijkaas, H. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.001081203 · Cited by 384
Health effects of passive smoking. 1. Parental smoking and lower respiratory illness in infancy and early childhood.
Strachan, D. P., & Cook, D. G. (1997) · Thorax · doi:10.1136/thx.52.10.905 · Cited by 383
Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors
Ifrim, D. C., Quintin, J., Joosten, L. A. B., Jacobs, C. W. M., Jansen, T., Jacobs, L., Gow, N. A. R., Williams, D. L., van der Meer, J. W. M., & Netea, M. G. (2014) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00688-13 · Cited by 373
Micronutrient malnutrition, infection, and immunity: An overview
Bhaskaram, P. (2002) · Nutrition Reviews · doi:10.1301/00296640260130722 · Cited by 361
Intraembryonic, but Not Yolk Sac Hematopoietic Precursors, Isolated before Circulation, Provide Long-Term Multilineage Reconstitution
Cumano, A., Ferraz, J. C., Klaine, M., Santo, J. P. D., & Godin, I. (2001) · Immunity · doi:10.1016/s1074-7613(01)00190-x · Cited by 345
Effects of Arsenic on Maternal and Fetal Health
Vahter, M. (2009) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-080508-141102 · Cited by 341
Pre- and Postnatal Exposure to Perfluorinated Compounds (PFCs)
Fromme, H., Mosch, C., Morovitz, M., Alba‐Alejandre, I., Boehmer, S., Kiranoglu, M., Faber, F. L., Hannibal, I., Genzel‐Boroviczény, O., Koletzko, B. V., et al. (2010) · Environmental Science & Technology · doi:10.1021/es101184f · Cited by 339
Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses: Gut microbiota and immune responses
Sjögren, Y. M., Tomicic, S., Lundberg, A., Böttcher, M. F., Björkstén, B., Sverremark‐Ekström, E., & Jenmalm, M. C. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2009.03326.x · Cited by 337
Zinc Deficiency, Infectious Disease and Mortality in the Developing World
Black, R. E. (2003) · Journal of Nutrition · doi:10.1093/jn/133.5.1485s · Cited by 335
Adverse health effects of prenatal and postnatal tobacco smoke exposure on children
Hofhuis, W. (2003) · Archives of Disease in Childhood · doi:10.1136/adc.88.12.1086 · Cited by 329
Pregnancy and Susceptibility to Infectious Diseases
Sappenfield, E. C., Jamieson, D. J., & Kourtis, A. P. (2013) · Infectious Diseases in Obstetrics and Gynecology · doi:10.1155/2013/752852 · Cited by 323
Impairment of Tetanus Toxoid-Specific Thl-like Immune Responses in Humans Infected with Schistosoma mansoni
Sabin, E., Araújo, M. I., Carvalho, E. M., & Pearce, E. J. (1996) · The Journal of Infectious Diseases · doi:10.1093/infdis/173.1.269 · Cited by 322
A Taxonomic Signature of Obesity in the Microbiome? Getting to the Guts of the Matter
Finucane, M. M., Sharpton, T. J., Laurent, T. J., & Pollard, K. S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0084689 · Cited by 321
Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor
Steel, J. H., Malatos, S., Kennea, N., Edwards, A. D., Miles, L., Duggan, P., Reynolds, P. R., Feldman, R. G., & Sullivan, M. H. F. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000153869.96337.90 · Cited by 317
Urinary Cadmium, Impaired Fasting Glucose, and Diabetes in the NHANES III
Schwartz, G. G., Il’yasova, D., & Ivanova, A. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.468 · Cited by 295
The role of the placenta in fetal exposure to heavy metals
Gundacker, C., & Hengstschläger, M. (2012) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-012-0074-3 · Cited by 293
Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases
Prescott, S. L. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.11.019 · Cited by 286
Preventing Tuberculosis with Bacillus Calmette-Guérin Vaccine: A Meta-Analysis of the Literature
Brewer, T. F. (2000) · Clinical Infectious Diseases · doi:10.1086/314072 · Cited by 283
Arsenic immunotoxicity: a review
Dangleben, N. L., Skibola, C. F., & Smith, M. T. (2013) · Environmental Health · doi:10.1186/1476-069x-12-73 · Cited by 280
Competing Interactions between Micro-RNAs Determine Neural Progenitor Survival and Proliferation after Ethanol Exposure: Evidence from an Ex Vivo Model of the Fetal Cerebral Cortical Neuroepithelium
Sathyan, P., Golden, H. B., & Miranda, R. C. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1269-07.2007 · Cited by 278
Early nutrition and immunity - progress and perspectives.
Calder, P. C., Krauss‐Etschmann, S., de Jong, E. C., Dupont, C. M., Frick, J.-S., Frøkiær, H., Heinrich, J., Garn, H., Koletzko, S., Lack, G., et al. (2006) · PubMed · doi:10.1017/bjn20061917 · Cited by 269
Plasmodium falciparum Isolates from Infected Pregnant Women and Children Are Associated with Distinct Adhesive and Antigenic Properties
Beeson, J. G., Brown, G. V., Molyneux, M. E., Mhango, C., Dzinjalamala, F., & Rogerson, S. J. (1999) · The Journal of Infectious Diseases · doi:10.1086/314899 · Cited by 266
Pathogens and the placental fortress
Robbins, J. R., & Bakardjiev, A. I. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.11.006 · Cited by 264
Prenatal or early postnatal events predict infectious deaths in young adulthood in rural Africa
Moore, S. E. (1999) · International Journal of Epidemiology · doi:10.1093/ije/28.6.1088 · Cited by 255
Prenatal Exposures to Persistent and Non‐Persistent Organic Compounds and Effects on Immune System Development
Hertz‐Picciotto, I., Park, H., Dostal, M., Kocan, A., Trnovec, T., & Sram, R. (2008) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2007.00190.x · Cited by 253
The Human Embryo, but Not Its Yolk Sac, Generates Lympho-Myeloid Stem Cells
Tavian, M., Robin, C., Coulombel, L., & Péault, B. (2001) · Immunity · doi:10.1016/s1074-7613(01)00193-5 · Cited by 231
Human Infection with Ascaris lumbricoides Is Associated with Suppression of the Interleukin-2 Response to Recombinant Cholera Toxin B Subunit following Vaccination with the Live Oral Cholera Vaccine CVD 103-HgR
Cooper, P. J., Chico, M. E., Sandoval, C. A., Espinel, I., Guevara, A., Levine, M. M., Griffin, G. E., & Nutman, T. B. (2001) · Infection and Immunity · doi:10.1128/iai.69.3.1574-1580.2001 · Cited by 231
Small Randomized Trial Among Low–birth-weight Children Receiving Bacillus Calmette-Guérin Vaccination at First Health Center Contact
Biering-Sørensen, S. R., Aaby, P., Napirna, B. M., Roth, A., Ravn, H., Rodrigues, A., Whittle, H. C., & Benn, C. S. (2011) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3182458289 · Cited by 226
Human milk metagenome: a functional capacity analysis
Ward, T., Hosid, S., Ioshikhes, I. P., & Altosaar, I. (2013) · BMC Microbiology · doi:10.1186/1471-2180-13-116 · Cited by 224
Reduced Antibody Responses to Vaccinations in Children Exposed to Polychlorinated Biphenyls
Heilmann, C. J., Grandjean, P., Weihe, P., Nielsen, F., & Budtz–Jørgensen, E. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030311 · Cited by 224
Characterizing the Pregnancy Immune Phenotype: Results of the Viral Immunity and Pregnancy (VIP) Study
Kraus, T., Engel, S. M., SPERLING, R. S., Kellerman, L., Lo, Y., Wallenstein, S. R., Escribese, M. M., Garrido, J. L. V., Singh, T., Loubeau, M., et al. (2011) · Journal of Clinical Immunology · doi:10.1007/s10875-011-9627-2 · Cited by 220
HIV-exposed uninfected children: a growing population with a vulnerable immune system?
Afran, L., Garcia-Knight, M., Nduati, E. W., Urban, B. C., Heyderman, R. S., & Rowland‐Jones, S. (2013) · Clinical & Experimental Immunology · doi:10.1111/cei.12251 · Cited by 219
Placental transfer and concentrations of cadmium, mercury, lead, and selenium in mothers, newborns, and young children
Chen, Z., Myers, R. A., Wei, T., Bind, E. P., Kassim, P. A., Wang, G., Ji, Y., Hong, X., Caruso, D., Bartell, T. R., et al. (2014) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2014.26 · Cited by 218
Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa
Martineau, A. R., Nhamoyebonde, S., Oni, T., Rangaka, M. X., Marais, S., Bangani, N., Tsekela, R., Bashe, L., Azevedo, V. D., Caldwell, J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111825108 · Cited by 210
Cytokines in Human Milk
Garofalo, R. P. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.11.019 · Cited by 205
Epigenetic Remodeling of the IL-2 and IFN -γ Loci in Memory CD8 T Cells Is Influenced by CD4 T Cells
Northrop, J. K., Thomas, R. M., Wells, A. D., & Shen, H. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.2.1062 · Cited by 203
Immunology of Parasitic Helminth Infections
MacDonald, A. S., Araújo, M. I., & Pearce, E. J. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.427-433.2002 · Cited by 202
Influence of BCG vaccine strain on the immune response and protection against tuberculosis
Ritz, N., Hanekom, W. A., Robins-Browne, R. M., Britton, W. J., & Curtis, N. C. (2008) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2008.00118.x · Cited by 201
Nutritionally Mediated Programming of the Developing Immune System
Palmer, A. C. (2011) · Advances in Nutrition · doi:10.3945/an.111.000570 · Cited by 198
Maternal smoking is associated with impaired neonatal toll-like-receptor-mediated immune responses
Noakes, P. S., Hale, J., Thomas, R., Lane, C., Devadason, S. G., & Prescott, S. L. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00050206 · Cited by 191
In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta
Wilhelm-Benartzi, C. S., Houseman, E. A., Maccani, M. A., Poage, G. M., Koestler, D. C., Langevin, S. M., Gagne, L. A., Banister, C. E., Padbury, J. F., & Marsit, C. J. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1103927 · Cited by 190
Alcohol Abuse in Pregnant Women: Effects on the Fetus and Newborn, Mode of Action and Maternal Treatment
Ornoy, A., & Ergaz, Z. (2010) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph7020364 · Cited by 188
Role of Innate Host Defenses in Susceptibility to Early-Onset Neonatal Sepsis
Wynn, J. L., & Levy, O. (2010) · Clinics in Perinatology · doi:10.1016/j.clp.2010.04.001 · Cited by 186
Foxp3+ Regulatory T Cell Expansion Required for Sustaining Pregnancy Compromises Host Defense against Prenatal Bacterial Pathogens
Rowe, J. H., Ertelt, J. M., Aguilera, M., Farrar, M. A., & Way, S. S. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.06.005 · Cited by 185
Differential DNA Methylation in Umbilical Cord Blood of Infants Exposed to Low Levels of Arsenic in Utero
Koestler, D. C., Avissar-Whiting, M., Houseman, E. A., Karagas, M. R., & Marsit, C. J. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205925 · Cited by 183
Immune Deficiency in Fetal Alcohol Syndrome
Johnson, S., Knight, R., Marmer, D. J., & Steele, R. W. (1981) · Pediatric Research · doi:10.1203/00006450-198106000-00005 · Cited by 177
Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections
Dauby, N., Goetghebuer, T., Kollmann, T. R., Lévy, J., & Marchant, A. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70341-3 · Cited by 177
Self-citation
Prenatal undernutrition, postnatal environments, and antibody response to vaccination in adolescence
McDade, T. W., Beck, M. A., Kuzawa, C. W., & Adair, L. S. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.4.543 · Cited by 172
Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S. W., Olek, S., Kohajda, T., Rolle-Kampczyk, U. E., von Bergen�, M., Sack, U., et al. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.06.036 · Cited by 172
Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of Human Blood Mononuclear Cells
Corbett, N., Blimkie, D., Ho, K., Cai, B., Sutherland, D. P., Kallos, A., Crabtree, J., Rein‐Weston, A., Lavoie, P. M., Turvey, S. E., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015041 · Cited by 170
Self-citation
Developmental exposure to TCDD reduces fertility and negatively affects pregnancy outcomes across multiple generations
Bruner‐Tran, K. L., & Osteen, K. G. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.10.003 · Cited by 164
The influence of the mode of delivery on circulating cytokine concentrations in the perinatal period
Malamitsi‐Puchner, A., Protonotariou, E., Boutsikou, Τ., Makrakis, E., Sarandakou, A., & Creatsas, G. K. (2005) · Early Human Development · doi:10.1016/j.earlhumdev.2004.10.017 · Cited by 162
Prenatal Arsenic Exposure and DNA Methylation in Maternal and Umbilical Cord Blood Leukocytes
Kile, M. L., Baccarelli, A., Hoffman, E. B., Tarantini, L., Quamruzzaman, Q., Rahman, M., Mahiuddin, G., Mostofa, G., Hsueh, Y., Wright, R. O., et al. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104173 · Cited by 155
In vitro evaluation of the immunotoxic potential of perfluorinated compounds (PFCs)
Corsini, E., Avogadro, A., Galbiati, V., Dell’Agli, M., Marinovich, M., Galli, C. L., & Germolec, D. R. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.11.004 · Cited by 153
Developmental Exposure to Lead Causes Persistent Immunotoxicity in Fischer 344 Rats
Miller, T. E., Golemboski, K. A., Ha, R. S., Bunn, T. L., Sanders, F. S., & Dietert, R. R. (1998) · Toxicological Sciences · doi:10.1093/toxsci/42.2.129 · Cited by 152
HIV-Exposed Uninfected Infants are at Increased Risk for Severe Infections in the First Year of Life
Slogrove, A. L., Reikie, B. A., Naidoo, S., de Beer, C., Ho, K., Cotton, M. F., Bettinger, J. A., Speert, D. P., Esser, M., & Kollmann, T. R. (2012) · Journal of Tropical Pediatrics · doi:10.1093/tropej/fms019 · Cited by 146
Self-citation
Month of birth, vitamin D and risk of immune-mediated disease: a case control study
Disanto, G., Chaplin, G., Morahan, J. M., Giovannoni, G., Hyppönen, E., Ebers, G. C., & Ramagopalan, S. V. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-69 · Cited by 138
Do Antenatal Parasite Infections Devalue Childhood Vaccination?
LaBeaud, A. D., Malhotra, I. J., King, M. J., King, C. L., & King, C. H. (2009) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000442 · Cited by 133
Neonatal Thyroid Function in Seveso 25 Years after Maternal Exposure to Dioxin
Baccarelli, A., Giacomini, S., Corbetta, C., Landi, M. T., Bonzini, M., Consonni, D., Grillo, P., Patterson, D. G., Pesatori, A. C., & Bertazzi, P. A. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050161 · Cited by 131
Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes
Pal‐Bhadra, M., Bhadra, U., Jackson, D. E., Mamatha, L., Park, P., & Shukla, S. D. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.07.030 · Cited by 129
Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line
Intarasunanont, P., Navasumrit, P., Waraprasit, S., Chaisatra, K., Suk, W. A., Mahidol, C., & Ruchirawat, M. (2012) · Environmental Health · doi:10.1186/1476-069x-11-31 · Cited by 128
Patterns and Implications of Naturally Acquired Immune Responses to Environmental and Tuberculous Mycobacterial Antigens in Northern Malawi
Black, G. F., Dockrell, H. M., Crampin, A. C., Floyd, S., Weir, R. E., Bliss, L., Sichali, L., Mwaungulu, L., Kanyongoloka, H., Ngwira, B. M., et al. (2001) · The Journal of Infectious Diseases · doi:10.1086/322042 · Cited by 126
T-lymphocyte subsets in West African children: Impact of age, sex, and season
Lisse, I. M., Aaby, P., Whittle, H. C., Jensen, H., Engelmann, M. D. M., & Christensen, L. B. (1997) · The Journal of Pediatrics · doi:10.1016/s0022-3476(97)70313-5 · Cited by 125
The effects of maternal helminth and malaria infections on mother-to-child HIV transmission
Gallagher, M., Malhotra, I. J., Mungai, P., Wamachi, A. N., Kioko, J. M., Ouma, J. H., Muchiri, E. M., & King, C. L. (2005) · AIDS · doi:10.1097/01.aids.0000189846.90946.5d · Cited by 123
Interaction of pregnancy and autoimmune rheumatic disease
Østensen, M., Villiger, P. M., & Förger, F. (2011) · Autoimmunity Reviews · doi:10.1016/j.autrev.2011.11.013 · Cited by 122
In Utero Arsenic Exposure Is Associated With Impaired Thymic Function in Newborns Possibly Via Oxidative Stress and Apoptosis
Ahmed, S., Ahsan, K., Kippler, M. J., Mily, A., Wagatsuma, Y., Hoque, A. M. W., N’Gom, P. T., Arifeen, S. E., Raqib, R., & Vahter, M. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs202 · Cited by 121
Non-specific effect of Bacille Calmette-Guérin vaccine on the immune response to routine immunisations
Ritz, N., Mui, M., Balloch, A., & Curtis, N. C. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.03.059 · Cited by 118
Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants
Burl, S., Townend, J., Njie-Jobe, J., Cox, M., Adetifa, U. J., Touray, E. S., Philbin, V. J., Mancuso, C. J., Kampmann, B., Whittle, H. C., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018185 · Cited by 118
HLA-G and HLA-E: fundamental and pathophysiological aspects
Carosella, E. D., Paul, P., Moreau, P., & Rouas‐Freiss, N. (2000) · Immunology Today · doi:10.1016/s0167-5699(00)01707-2 · Cited by 117
BCG Vaccination Induces Different Cytokine Profiles Following Infant BCG Vaccination in the UK and Malawi
Lalor, M. K., Floyd, S., Gorak‐Stolinska, P., Ben‐Smith, A., Weir, R. E., Smith, S. G., Newport, M. J., Blitz, R., Mvula, H., Branson, K. R., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir515 · Cited by 111
PCB exposure in utero and via breast milk. A review
Dekoning, E. P., & Karmaus, W. J. J. (2000) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/sj.jea.7500090 · Cited by 110
Growth faltering due to breastfeeding cessation in uninfected children born to HIV-infected mothers in Zambia
Arpadi, S. M., Fawzy, A., Aldrovandi, G. M., Kankasa, C., Sinkala, M., Mwiya, M., Thea, D. M., & Kuhn, L. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27745 · Cited by 109
Cytokines and other immunological biomarkers in children's environmental health studies
Duramad, P., Tager, I. B., & Holland, N. (2007) · Toxicology Letters · doi:10.1016/j.toxlet.2007.05.017 · Cited by 105
Immune cell counts and risks of respiratory infections among infants exposed pre- and postnatally to organochlorine compounds: a prospective study
Glynn, A. W., Thuvander, A., Aune, M., Johannisson, A., Darnerud, P. O., Ronquist, G., & Cnattingius, S. (2008) · Environmental Health · doi:10.1186/1476-069x-7-62 · Cited by 103
Maternal filarial infection as risk factor for infection in children
Lammie, P. J., Hitch, W. L., Walker, E. M., Hightower, A. W., & Eberhard, M. L. (1991) · The Lancet · doi:10.1016/0140-6736(91)92661-k · Cited by 102
Infection with parasitic nematodes confounds vaccination efficacy
Urban, J. F., Steenhard, N. R., Solano-Aguilar, G. I., Dawson, H. D., Iweala, O. I., Nagler‐Anderson, C., Noland, G. S., Kumar, N., Anthony, R. M., Shea‐Donohue, T., et al. (2007) · Veterinary Parasitology · doi:10.1016/j.vetpar.2007.05.006 · Cited by 96
Nutrition and the Immune System
Kubena, K. S., & McMurray, D. N. (1996) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(96)00297-0 · Cited by 94
Developmental Immunotoxicology: Focus on Health Risks
Dietert, R. R. (2008) · Chemical Research in Toxicology · doi:10.1021/tx800198m · Cited by 93
Immune modulation by helminthic infections: worms and viral infections
Kamal, S. M., & Khalifa, K. (2006) · Parasite Immunology · doi:10.1111/j.1365-3024.2006.00909.x · Cited by 92
Early life response to infection
Ghazal, P., Dickinson, P., & Smith, C. (2013) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e32835fb8bf · Cited by 92
In-utero exposure to maternal HIV infection alters T-cell immune responses to vaccination in HIV-uninfected infants
Kidzeru, E. B., Hesseling, A. C., Passmore, J.-A. S., Myer, L., Gamieldien, H., Tchakoute, C. T., Gray, C. M., Sodora, D. L., & Jaspan, H. B. (2014) · AIDS · doi:10.1097/qad.0000000000000292 · Cited by 91
Prenatal and childhood Mediterranean diet and the development of asthma and allergies in children
Chatzi, L., & Kogevinas, M. (2009) · Public Health Nutrition · doi:10.1017/s1368980009990474 · Cited by 91
Prenatal immunotoxicant exposure and postnatal autoimmune disease.
Holladay, S. D. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.99107s5687 · Cited by 89
Maternal Alcohol Abuse and Neonatal Infection
Gauthier, T. W., Drews‐Botsch, C., Falek, A., Coles, C. D., & Brown, L. A. S. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000167956.28160.5e · Cited by 88
Human Immunodeficiency Virus (HIV)–Specific Cellular Immune Responses in Newborns Exposed to HIV In Utero
Kuhn, L., Meddows‐Taylor, S., Gray, G., & Tiemessen, C. T. (2002) · Clinical Infectious Diseases · doi:10.1086/338153 · Cited by 86
Survival of Infants Born to HIV-Positive Mothers, by Feeding Modality, in Rakai, Uganda
Kagaayi, J., Gray, R. H., Brahmbhatt, H., Kigozi, G., Nalugoda, F. K., Wabwire‐Mangen, F., Serwadda, D., Sewankambo, N. K., Ddungu, V., Ssebagala, D., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003877 · Cited by 84
CORD BLOOD LYMPHOCYTE FUNCTIONS IN NEWBORNS FROM A REMOTE MARITIME POPULATION EXPOSED TO ORGANOCHLORINES AND METHYLMERCURY
Belles‐Isles, M., Ayotte, P., Dewailly, É., Weber, J., & Roy, R. (2002) · Journal of Toxicology and Environmental Health · doi:10.1080/152873902753396794 · Cited by 84
Nonspecific Effects of Vaccines and the Reduction of Mortality in Children
Shann, F. A. (2013) · Clinical Therapeutics · doi:10.1016/j.clinthera.2013.01.007 · Cited by 83
Altered Innate Immune Development in HIV-Exposed Uninfected Infants
Reikie, B. A., Adams, R. C. M., Leligdowicz, A., Ho, K., Naidoo, S., Ruck, C. E., de Beer, C., Preiser, W., Cotton, M. F., Speert, D. P., et al. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000161 · Cited by 80
Self-citation
Commensal Bacteria and Expression of Two Major Intestinal Chemokines, TECK/CCL25 and MEC/CCL28, and Their Receptors
Meurens, F., Berri, M., Siggers, R. H., Willing, B. P., Salmon, H., Kessel, A. G. V., & Gerdts, V. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000677 · Cited by 73
Antibody Responses to Vaccination among South African HIV-Exposed and Unexposed Uninfected Infants during the First 2 Years of Life
Reikie, B. A., Naidoo, S., Ruck, C. E., Slogrove, A. L., de Beer, C., la Grange, H., Adams, R. C. M., Ho, K., Smolen, K. K., Speert, D. P., et al. (2012) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00557-12 · Cited by 73
Self-citation
Impaired Humoral Response to Vaccines among HIV-Exposed Uninfected Infants
Abramczuk, B. M., Mazzola, T. N., Moreno, Y. M. F., Zorzeto, T. Q., Quintilio, W., Wolf, P. S., Blotta, M. H. S. L., Morcillo, A. M., da Silva, M. T. N., & Vilela, M. M. D. S. (2011) · Clinical and Vaccine Immunology · doi:10.1128/cvi.05065-11 · Cited by 71
Influence of Maternal Filariasis on Childhood Infection and Immunity toWuchereria bancroftiin Kenya
Malhotra, I. J., Ouma, J. H., Wamachi, A. N., Kioko, J., Mungai, P., Njzovu, M., Kazura, J. W., & King, C. L. (2003) · Infection and Immunity · doi:10.1128/iai.71.9.5231-5237.2003 · Cited by 71
Prenatal T Cell Immunity toWuchereria bancroftiand Its Effect on Filarial Immunity and Infection Susceptibility during Childhood
Malhotra, I. J., Mungai, P., Wamachi, A. N., Tisch, D. J., Kioko, J. M., Ouma, J. H., Muchiri, E. M., Kazura, J. W., & King, C. L. (2006) · The Journal of Infectious Diseases · doi:10.1086/500472 · Cited by 70
Nutrition in early life, immune-programming and allergies: the role of epigenetics.
Amarasekera, M., Prescott, S. L., & Palmer, D. J. (2013) · PubMed · Cited by 66
HIV, infant feeding and more perils for poor people: new WHO guidelines encourage review of formula milk policies
Coutsoudis, A. (2008) · Bulletin of the World Health Organization · doi:10.2471/blt.07.041673 · Cited by 66
What, if any, is the effect of malnutrition on immunological competence?
Morgan, G. J. (1997) · The Lancet · doi:10.1016/s0140-6736(96)12038-9 · Cited by 65
Influence of Socioeconomic Status Trajectories on Innate Immune Responsiveness in Children
Azad, M. B., Lissitsyn, Y., Miller, G. E., Becker, A. B., HayGlass, K. T., & Kozyrskyj, A. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038669 · Cited by 64
Current Status of Developmental Immunotoxicity
DeWitt, J. C., Peden‐Adams, M. M., Keil, D. E., & Dietert, R. R. (2011) · Toxicologic Pathology · doi:10.1177/0192623311427709 · Cited by 64
Role of diet in the development of immune tolerance in the context of allergic disease
West, C. E., Videky, D. J., & Prescott, S. L. (2010) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e32833d96ef · Cited by 62
Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines
Levy, O., & Netea, M. G. (2013) · Pediatric Research · doi:10.1038/pr.2013.214 · Cited by 61
Induction of Antigen-Specific Immunity in Human Neonates and Infants
Wilson, C. B., & Kollmann, T. R. (2008) · KARGER eBooks · doi:10.1159/000113493 · Cited by 60
Self-citation
Pattern recognition receptor-mediated cytokine response in infants across 4 continents⋆
Smolen, K. K., Ruck, C. E., Fortuno, E. S., Ho, K., Dimitriu, P. A., Mohn, W. W., Speert, D. P., Cooper, P. J., Esser, M., Goetghebuer, T., et al. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.09.038 · Cited by 57
Self-citation
Unique Gene Expression Profiles in Infants Vaccinated with Different Strains ofMycobacterium bovisBacille Calmette-Guerin
Wu, B., Huang, C., García‐García, L., Ponce‐de‐León, A., Sifuentes‐Osornio, J., Bobadilla-del-Valle, M., Ferreira, L., Canizales‐Quintero, S., Small, P. M., Kato‐Maeda, M., et al. (2007) · Infection and Immunity · doi:10.1128/iai.00244-07 · Cited by 56
Half-life of each dioxin and PCB congener in the human body
Ogura, I. (2004) · Cited by 53
Blood-Forming Endothelium in Human Ontogeny: Lessons From In Utero Development and Embryonic Stem Cell Culture
Zambidis, E. T., Oberlin, E., Tavian, M., & Péault, B. (2006) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2006.01.005 · Cited by 52
1999 Pediatric Academic Societies' Annual Meeting
(1999) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.153.4.418 · Cited by 52
Effect of Cadmium Body Burden on Immune Response of School Children
Ritz, B. R., Heinrich, J., Wjst, M., Wichmann, E., & Krause, C. (1998) · Archives of Environmental Health An International Journal · doi:10.1080/00039899809605708 · Cited by 51
Evidence for In Utero Sensitization toAscaris lumbricoidesin Newborns of Mothers with Ascariasis
Guadalupe, I., Mitre, E. E. S., Benitez, S. M., Chico, M. E., Nutman, T. B., & Cooper, P. J. (2009) · The Journal of Infectious Diseases · doi:10.1086/599214 · Cited by 51
Effects of Cessation of Breastfeeding in HIV-1-Exposed, Uninfected Children in Malawi
Taha, T. E., Hoover, D. R., Chen, S., Kumwenda, J., Mipando, L., Nkanaunena, K., Thigpen, M. C., Taylor, A. W., Fowler, M. G., & MOFENSON, L. M. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir413 · Cited by 51
Molecular interactions in the placenta during malaria infection
Mens, P. F., Bojtor, E. C., & Schallig, H. D. F. H. (2010) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2010.05.013 · Cited by 48
Immune function in rural Gambian children is not related to season of birth, birth size, or maternal supplementation status
Moore, S. E., Collinson, A. C., & Prentice, A. M. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.6.840 · Cited by 48
Impact of maternal HIV-1 viremia on lymphocyte subsets among HIV-exposed uninfected infants: protective mechanism or immunodeficiency
Kakkar, F., Lamarre, V., Ducruet, T., Boucher, M., Valois, S., Soudeyns, H., & Lapointe, N. (2014) · BMC Infectious Diseases · doi:10.1186/1471-2334-14-236 · Cited by 47
The Plausibility of Micronutrient Deficiency in Relationship to Perinatal Infection
Goldenberg, R. L. (2003) · Journal of Nutrition · doi:10.1093/jn/133.5.1645s · Cited by 47
Decrease in the Effectiveness of Bacille Calmette‐Guérin Vaccine against Pulmonary Tuberculosis: A Consequence of Increased Immune Suppression by Microbial Antioxidants, Not Overattenuation
Kernodle, D. S. (2010) · Clinical Infectious Diseases · doi:10.1086/653533 · Cited by 44
Ontogeny of Toll-Like and NOD-Like Receptor-Mediated Innate Immune Responses in Papua New Guinean Infants
Lisciandro, J. G., Prescott, S. L., Nadal‐Sims, M. G., Devitt, C. J., Pomat, W. S., Siba, P. M., Tulić, M. K., Holt, P. G., Strickland, D. H., & van den Biggelaar, A. H. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036793 · Cited by 41
Maternal Geohelminth Infections Are Associated with an Increased Susceptibility to Geohelminth Infection in Children: A Case-Control Study
Mehta, R. S., Rodríguez, A., Chico, M. E., Guadalupe, I., Broncano, N., Sandoval, C. A., Tupiza, F., Mitre, E. E. S., & Cooper, P. J. (2012) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0001753 · Cited by 40
Birth season and environmental influences on blood leucocyte and lymphocyte subpopulations in rural Gambian infants
Collinson, A. C., N’Gom, P. T., Moore, S. E., Morgan, G., & Prentice, A. M. (2008) · BMC Immunology · doi:10.1186/1471-2172-9-18 · Cited by 38
Colostrum-derived B and T cells as an extra-lymphoid compartment of effector cell populations in humans
Peroni, D. G., Chirumbolo, S., Veneri, D., PIACENTINI, G. L., Tenero, L., Vella, A., Ortolani, R., Raffaelli, R., & Boner, A. L. (2012) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2012.733744 · Cited by 37
The Effect of Maternal Helminth Infection on Maternal and Neonatal Immune Function and Immunity to Tuberculosis
Hagos, D. G., Desta, K., Desalegn, G., Howe, R., & Abebe, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093429 · Cited by 29
Immune response to Bordetella pertussis is associated with season and undernutrition in Senegalese children
Gaayeb, L., Pinçon, C., Cames, C., Sarr, J.-B., Seck, M., Schacht, A., Remoué, F., Hermann, E., & Riveau, G. J. (2014) · Vaccine · doi:10.1016/j.vaccine.2014.03.086 · Cited by 28
Maternal Selenium Nutrition and Neonatal Immune System Development
Dylewski, M. L., Mastro, A. M., & Picciano, M. F. (2002) · Neonatology · doi:10.1159/000063088 · Cited by 27
HLA class I expression in the human placenta
Juch, H., Blaschitz, A., Dohr, G., & Hutter, H. (2012) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-012-0070-7 · Cited by 26
The Immune System and Exposure to Xenobiotics in Animals
Cabassi, E. (2007) · Veterinary Research Communications · doi:10.1007/s11259-007-0074-8 · Cited by 26
Prenatal Immunotoxicant Exposure and Postnatal Autoimmune Disease
Holladay, S. D. (1999) · Environmental Health Perspectives · doi:10.2307/3434328 · Cited by 21
The Window of Opportunity: Pre-Pregnancy to 24 Months of Age
(2008) · Nestlé Nutrition Institute Workshop series · doi:10.1159/isbn.978-3-8055-8388-6 · Cited by 17
HIV, infant feeding and more perils for poor people: new WHO guidelines encourage review of formula milk policies
Coutsoudis, A. (2008) · Bulletin of the World Health Organization · doi:10.2471/blt.07.041679 · Cited by 15
Long-term effects of perinatal nutrition on T lymphocyte kinetics in young Gambian men
Ghattas, H., Wallace, D. L., Solon, J. A., Henson, S. M., Zhang, Y., N’Gom, P. T., Aspinall, R., Morgan, G., Griffin, G. E., Prentice, A. M., et al. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.480 · Cited by 11
Mode of Delivery and Inflammatory Disorders
Ghia, J., & Khafipour, E. (2013) · Cited by 6
Chronic maternal infections during pregnancy
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Panigrahi, 2013, Effectiveness of a Lactobacillus plantarum synbiotic therapy for preventing late onset sepsis in neonates [abstract]

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Authors: MacGillivray, D. M., & Kollmann, T. R.
Affiliations: University of British Columbia (CA)
Corresponding author: Kollmann, Tobias R.
ORCID: Kollmann, Tobias R.
Venue: Frontiers in Immunology
Publisher: Frontiers Media SA
Published: 2014-09-12
Volume: 5
Pages: 434-434
ISSN: 1664-3224 (ISSN-L)
DOI: 10.3389/fimmu.2014.00434
PMC: PMC4161944
OpenAlex: W2077870918
Cited by: 219
References: 182
Citations by year: 2026: 15 · 2025: 27 · 2024: 19 · 2023: 22 · 2022: 24 · 2021: 33 · 2020: 22 · 2019: 17 · 2018: 13 · 2017: 14 · 2016: 6 · 2015: 7
FWCI: 0.88
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: Frontiers in Immunology (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Burroughs Wellcome Fund
Michael Smith Health Research BC
Topics: Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
Keywords: environmental factors, immune system development, early life, immunological memory, innate immunity, adaptive immunity, pathogen-associated molecular patterns, damage-associated molecular patterns, evolutionary immunology, immune system evolution

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The Role of Environmental Factors in Modulating Immune Responses in Early Life

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