Cited by 160Neuroscience and Neural EngineeringEEG and Brain-Computer InterfacesUndergraduate Neuroscience Education and Research

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Biocompatibility of intracortical microelectrodes: current status and future prospects

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Marin, Cristina·2010·Frontier in Neuroengineering

DOI 10.3389/fneng.2010.00008PMC PMC2889721

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Abstract

Rehabilitation of sensory and/or motor functions in patients with neurological diseases is more and more dealing with artificial electrical stimulation and recording from populations of neurons using biocompatible chronic implants. As more and more patients have benefited from these approaches, the interest in neural interfaces has grown significantly. However an important problem reported with all available microelectrodes to date is long-term viability and biocompatibility. Therefore it is essential to understand the signals that lead to neuroglial activation and create a targeted intervention to control the response, reduce the adverse nature of the reactions and maintain an ideal environment for the brain-electrode interface. We discuss some of the exciting opportunities and challenges that lie in this intersection of neuroscience research, bioengineering, neurology and biomaterials.

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On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772
Response of brain tissue to chronically implanted neural electrodes
Polikov, V. S., Tresco, P. A., & Reichert, W. M. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2005.08.015 · Cited by 1,896
The glial scar and central nervous system repair
Fawcett, J. W., & Asher, R. A. (1999) · Brain Research Bulletin · doi:10.1016/s0361-9230(99)00072-6 · Cited by 1,808
Molecular profile of reactive astrocytes—Implications for their role in neurologic disease
Eddleston, M., & Mucke, L. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90380-x · Cited by 1,441
Neuronal cell loss accompanies the brain tissue response to chronically implanted silicon microelectrode arrays
Biran, R., Martin, D. C., & Tresco, P. A. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.04.020 · Cited by 893
Brain responses to micro-machined silicon devices
Szarowski, D. H., Andersen, M. D., Retterer, S. T., Spence, A. J., Isaacson, M. S., Craighead, H. G., Turner, J. N., & Shain, W. G. (2003) · Brain Research · doi:10.1016/s0006-8993(03)03023-3 · Cited by 811
Carbon Nanotube Substrates Boost Neuronal Electrical Signaling
Lovat, V., Pantarotto, D., Lagostena, L., Cacciari, B., Grandolfo, M., Righi, M., Spalluto, G., Prato, M., & Ballerini, L. (2005) · Nano Letters · doi:10.1021/nl050637m · Cited by 648
Flexible polyimide-based intracortical electrode arrays with bioactive capability
Rousche, P. J., Pellinen, D. S., Pivin, D. P., Williams, J. C., Vetter, R. J., & Kipke, D. R. (2001) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.914800 · Cited by 644
Chronic neural recordings using silicon microelectrode arrays electrochemically deposited with a poly(3,4-ethylenedioxythiophene) (PEDOT) film
Ludwig, K. A., Uram, J. D., Yang, J., Martin, D. C., & Kipke, D. R. (2006) · Journal of Neural Engineering · doi:10.1088/1741-2560/3/1/007 · Cited by 638
Cerebral Astrocyte Response to Micromachined Silicon Implants
Turner, J. N., Shain, W. G., Szarowski, D. H., Andersen, M., Martins, S., Isaacson, M. S., & Craighead, H. G. (1999) · Experimental Neurology · doi:10.1006/exnr.1998.6983 · Cited by 603
Implanted Neural Interfaces: Biochallenges and Engineered Solutions
Grill, W. M., Norman, S. E., & Bellamkonda, R. V. (2009) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-061008-124927 · Cited by 488
Principles of neural ensemble physiology underlying the operation of brain–machine interfaces
Nicolelis, M. A. L., & Lebedev, M. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2653 · Cited by 486
Factors influencing the biocompatibility of insertable silicon microshafts in cerebral cortex
Edell, D. J., Toi, V. V., McNeil, V. M., & Clark, L. D. (1992) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.141202 · Cited by 481
Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration
McConnell, G. C., Rees, H. D., Levey, A. I., Gutekunst, C.-A., Gross, R. E., & Bellamkonda, R. V. (2009) · Journal of Neural Engineering · doi:10.1088/1741-2560/6/5/056003 · Cited by 480
Neural probe design for reduced tissue encapsulation in CNS
Seymour, J. P., & Kipke, D. R. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.03.024 · Cited by 462
A neural interface for a cortical vision prosthesis
Normann, R. A., Maynard, E. M., Rousche, P. J., & Warren, D. J. (1999) · Vision Research · doi:10.1016/s0042-6989(99)00040-1 · Cited by 411
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Hoogerwerf, A. C., & Wise, K. D. (1994) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.335862 · Cited by 372
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Mazzatenta, A., Giugliano, M., Campidelli, S., Gambazzi, L., Businaro, L., Markram, H., Prato, M., & Ballerini, L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1051-07.2007 · Cited by 348
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Crompton, K. E., Goud, J. D., Bellamkonda, R. V., Gengenbach, T. R., Finkelstein, D. I., Horne, M. K., & Forsythe, J. S. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.08.044 · Cited by 331
Dexamethasone-coated neural probes elicit attenuated inflammatory response and neuronal loss compared to uncoated neural probes
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Richardson, R. T., Wise, A. K., Thompson, B. C., Flynn, B. O., Atkinson, P. J., Fretwell, N. J., Fallon, J. B., Wallace, G. G., Shepherd, R. K., Clark, G. M., et al. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.01.015 · Cited by 304
Toward a comparison of microelectrodes for acute and chronic recordings
Ward, M. P., Rajdev, P., Ellison, C., & Irazoqui, P. P. (2009) · Brain Research · doi:10.1016/j.brainres.2009.05.052 · Cited by 296
Biomechanical analysis of silicon microelectrode-induced strain in the brain
Lee, H., Bellamkonda, R. V., Sun, W., & Levenston, M. E. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/4/003 · Cited by 281
Stability of the interface between neural tissue and chronically implanted intracortical microelectrodes
Liu, X., McCreery, D. B., Carter, R. R., Bullara, L. A., Yuen, T. G. H., & Agnew, W. F. (1999) · IEEE Transactions on Rehabilitation Engineering · doi:10.1109/86.788468 · Cited by 272
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Truccolo, W., Friehs, G. M., Donoghue, J. P., & Hochberg, L. R. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4415-07.2008 · Cited by 268
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Asplund, M., Thaning, E., Lundberg, J., Sandberg-Nordqvist, A.-C., Kostyszyn, B., Inganäs, O., & von Holst, H. (2009) · Biomedical Materials · doi:10.1088/1748-6041/4/4/045009 · Cited by 228
Chronic response of adult rat brain tissue to implants anchored to the skull
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Insertion shuttle with carboxyl terminated self-assembled monolayer coatings for implanting flexible polymer neural probes in the brain
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Long-term histological and electrophysiological results of an inactive epiretinal electrode array implantation in dogs.
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Normann, R. A. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0556 · Cited by 170
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Ganguly, K., Secundo, L., Ranade, G. V., Orsborn, A. L., Chang, E. F., Dimitrov, D. F., Wallis, J. D., Barbaro, N. M., Knight, R. T., & Carmena, J. M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2471-09.2009 · Cited by 152
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McCreery, D. B., Agnew, W. F., & Bullara, L. A. (2002) · Annals of Biomedical Engineering · doi:10.1114/1.1430748 · Cited by 77
Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade
Agnew, B. J., Duman, J. G., Watson, C., Coling, D., & Forte, J. G. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.16.2639 · Cited by 71
Bioactive properties of nanostructured porous silicon for enhancing electrode to neuron interfaces
Moxon, K. A., Hallman, S. J., Aslani, A., Kalkhoran, N. M., & Lelkes, P. I. (2007) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856207782177882 · Cited by 69
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Rennaker, R. L., Street, S. E., Ruyle, A. M., & Sloan, A. M. (2004) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.08.009 · Cited by 68
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Pancrazio, J. J. (2008) · Nanomedicine · doi:10.2217/17435889.3.6.823 · Cited by 64
Easily made single-walled carbon nanotube surface microelectrodes for neuronal applications
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Histopathologic and Physiologic Effects of Chronic Implantation of Microelectrodes in Sacral Spinal Cord of the Cat
Woodford, B. J., Carter, R. R., McCreery, D. B., Bullara, L. A., & Agnew, W. F. (1996) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199609000-00005 · Cited by 47
Methods for Simultaneous Multisite Neural Ensemble Recordings in Behaving Primates
Brisben, A., Nicolelis, M. A. L., Laubach, M., & Stambaugh, C. R. (1998) · Frontiers in neuroscience · doi:10.1201/9781420048254.ch7 · Cited by 41
Implantable microsystems. Polyimide-based neuroprostheses for interfacing nerves.
Stieglitz, T., & Ju, M. (1999) · PubMed · Cited by 37
‘Who is the ideal candidate?’: decisions and issues relating to visual neuroprosthesis development, patient testing and neuroplasticity.
Merabet, L. B., Rizzo, J. F., Pascual-Leone, A., & Fernandez, E. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s15 · Cited by 35
Central pain syndrome: elucidation of genesis and treatment
Canavero, S., & Bonicalzi, V. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.11.1485 · Cited by 34
Three-dimensional hydrogel cultures for modeling changes in tissue impedance around microfabricated neural probes
Frampton, J. P., Hynd, M. R., Williams, J. C., Shuler, M. L., & Shain, W. G. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/4/006 · Cited by 31
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Nicolelis, M. A. L. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.083709 · Cited by 29
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Köhler, K., Hartmann, J. A., Werts, D. E., & Zrenner, E. (2001) · Der Ophthalmologe · doi:10.1007/s003470170142 · Cited by 28
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Neural Prostheses in Clinical Applications – Trends from Precision Mechanics towards Biomedical Microsystems in Neurological Rehabilitation / Neuroprothesen in der klinischen Anwendung – Trends von der Feinwerktechnik zu biomedizinischen Mikrosystemen in der neurologischen Rehabilitation
Stieglitz, T., Schüettler, M., & Koch, K. P. (2004) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt.2004.015 · Cited by 17
Advances in cerebral probing using modular multifunctional probe arrays.
Neves, H. P. (2007) · PubMed · Cited by 5
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Authors: Marin, C.
Affiliations: Universitat de Miguel Hernández d'Elx (ES)
Corresponding author: Marin, Cristina
Venue: Frontier in Neuroengineering
Publisher: Frontiers Media SA
Published: 2010
Volume: 3
Pages: 8-8
ISSN: 1662-6443 (ISSN-L)
DOI: 10.3389/fneng.2010.00008
PMC: PMC2889721
OpenAlex: W2071949955
Cited by: 160
References: 62
Citations by year: 2026: 5 · 2025: 13 · 2024: 3 · 2023: 10 · 2022: 7 · 2021: 16 · 2020: 11 · 2019: 7 · 2018: 12 · 2017: 11 · 2016: 13 · 2015: 6 · 2014: 13 · 2013: 12 · 2012: 8
FWCI: 4.27
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
Locations: Frontiers in Neuroengineering (publishedVersion, cc-by)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: European Commission
Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
Social Sciences › Education › Undergraduate Neuroscience Education and Research
Keywords: intracortical microelectrodes, biocompatibility, neural interfaces, neural recording, electrical stimulation, biomaterials

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Biocompatibility of intracortical microelectrodes: current status and future prospects

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