Cited by 105Neuroscience and Neural EngineeringTactile and Sensory InteractionsEEG and Brain-Computer Interfaces

Development of a cortical visual neuroprosthesis for the blind: the relevance of neuroplasticity

Fernández, E, Pelayo, F, Romero, S, Bongard, M, Marin, C, Alfaro, A, Merabet, L·2005·Journal of Neural Engineering

Abstract

Clinical applications such as artificial vision require extraordinary, diverse, lengthy and intimate collaborations among basic scientists, engineers and clinicians. In this review, we present the state of research on a visual neuroprosthesis designed to interface with the occipital visual cortex as a means through which a limited, but useful, visual sense could be restored in profoundly blind individuals. We review the most important physiological principles regarding this neuroprosthetic approach and emphasize the role of neural plasticity in order to achieve desired behavioral outcomes. While full restoration of fine detailed vision with current technology is unlikely in the immediate near future, the discrimination of shapes and the localization of objects should be possible allowing blind subjects to navigate in a unfamiliar environment and perhaps even to read enlarged text. Continued research and development in neuroprosthesis technology will likely result in a substantial improvement in the quality of life of blind and visually impaired individuals.

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Crossref · 10.1088/1741-2560/2/4/r01

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112 of 112 references verified0 citation errors · 0 not checkable

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  • In response to the loss of vision, brain areas normally devoted to the processing of visual information are recruited to process tactile and auditory information and even cognitive functions such as verbal memory and speech processing.

    “In response to the loss of vision, brain areas normally devoted to the processing of visual information are recruited to process tactile and auditory information and even cognitive functions such as verbal memory and speech processing (Fernandez et al., 2005; Gilbert et al., 2009; Legge and Chung, 2016; Beyeler et al., 2017; Singh et al., 2018; Castaldi et al., 2020).”

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Authors
Fernández, E., Pelayo, F., Romero, S., Bongard, M., Marin, C., Alfaro, A., & Merabet, L.
Affiliations
  • Universitat de Miguel Hernández d'Elx (ES)
  • Universidad de Granada (ES)
Venue
Journal of Neural Engineering
Published
2005-11-29
Volume
2
Issue
4
Pages
R1-R12
ISSN
  • 1741-2552 (ISSN-L)
  • 1741-2560
OpenAlex
W2063850540
Cited by
105
References
113
Citations by year
2025: 1 · 2023: 1 · 2022: 7 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 7 · 2014: 6 · 2013: 4 · 2012: 8
FWCI
0.51
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Neural Engineering (publishedVersion)
  • PubMed (publishedVersion)
Funders
University of Utah
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
Keywords
cortical visual prosthesis, neuroplasticity, blindness, vision restoration, shape discrimination, object localization, navigation, visually impaired people
MeSH terms
Artificial Intelligence, Blindness, Electric Stimulation Therapy, Humans, Neuronal Plasticity, Optic Nerve, Prosthesis Design, Retinal Ganglion Cells, Visual Cortex, Prostheses and Implants

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