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LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease
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“while LRPAP1 can bind domains II, III and IV in competition with all known ligands (46–50).”
From LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation (2023) · cites this paper as [46]
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“LRP1 has four potential ligand-binding domains: domain I does not bind any known ligands, domains II and IV binds all known ligands (46), and domain III binds ApoE and blood coagulation factor VIII (47, 48)”
From LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation (2023) · cites this paper as [46]
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Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders
Zlokovic, B. V. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3114 · Cited by 2,969
Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders
Ballatore, C., Lee, V. M.-Y., & Trojanowski, J. Q. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2194 · Cited by 2,174
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RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
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Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
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apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
Deane, R., Sagare, A., Hamm, K., Parisi, M., Lane, S., Finn, M. B., Holtzman, D. M., & Zlokovic, B. V. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36663 · Cited by 771
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Reid, K. M., & Brown, G. C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1286474 · Cited by 13
Metadata
- Authors
- Spuch, C., Ortolano, S., & Navarro, C.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2012
- Volume
- 3
- ISSN
- 1664-042X
- PMC
- PMC3429044
- Cited by
- 107
- References
- 20
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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