Dual Roles of Astrocyte-Derived Factors in Regulation of Blood-Brain Barrier Function after Brain Damage

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Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease

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The Role of Astrocytes in Multiple Sclerosis

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Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

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MicroRNA-21 Regulates Astrocytic Response Following Spinal Cord Injury

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Retinoic Acid Induces Blood–Brain Barrier Development

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Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood–Brain Barrier Permeability During Early Reperfusion in Stroke

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MicroRNA-29b is a Therapeutic Target in Cerebral Ischemia Associated with Aquaporin 4

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Recombinant Human Sonic Hedgehog Protein Regulates the Expression of ZO-1 and Occludin by Activating Angiopoietin-1 in Stroke Damage

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Early VEGF inhibition attenuates blood-brain barrier disruption in ischemic rat brains by regulating the expression of MMPs

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Plasma Angiopoietin-1 Is Lower After Ischemic Stroke and Associated With Major Disability But Not Stroke Incidence

Golledge, J., Clancy, P., Maguire, J. M., Lincz, L. F., Koblar, S. A., McEvoy, M., Attia, J., Levi, C. R., Sturm, J. W., Almeida, O. P., et al. (2014) · Stroke · doi:10.1161/strokeaha.113.004339 · Cited by 30

Pretreatment with 17β-Estradiol Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption in Aged Rats: Involvement of Antioxidant Signaling

Xiao, H., Deng, M., Yang, B., Hu, Z., & Tang, J. (2017) · Neuroendocrinology · doi:10.1159/000455866 · Cited by 30

MicroRNA-711–Induced Downregulation of Angiopoietin-1 Mediates Neuronal Cell Death

Sabirzhanov, B. E., Faden, A. I., Aubrecht, T. G., Henry, R. J., Glaser, E. P., & Stoica, B. A. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5572 · Cited by 29

Endothelin-1 is over-expressed in amyotrophic lateral sclerosis and induces motor neuron cell death

Ranno, E., D’Antoni, S., Spatuzza, M., Berretta, A., Laureanti, F., Bonaccorso, C. M., Pellitteri, R., Longone, P., Spalloni, A., Iyer, A. M., et al. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.01.002 · Cited by 28

Inhibition of astrocytic activity alleviates sequela in acute stages of intracerebral hemorrhage

Chiu, C., Yao, N.-W., Guo, J., Shen, C., Lee, H., Chiu, Y.-P., Ji, H.-R., Chen, X., Chen, C., & Chang, C. (2017) · Oncotarget · doi:10.18632/oncotarget.22022 · Cited by 28

Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function

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Estrogen regulates the expression of Ndrg2 in astrocytes

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The inhibition of Rho kinase blocks cell migration and accumulation possibly by challenging inflammatory cytokines and chemokines on astrocytes

Guo, M., Meng, J., Lǐ, Y., Yu, J., Liu, C., Ling, F., Yang, W., Li, J., Feng, Q., Xiao, B., et al. (2014) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2014.05.034 · Cited by 25

Sonic hedgehog signalling pathway regulates apoptosis through Smo protein in human umbilical vein endothelial cells

Zhu, S., Luo, M., Peng, W., Li, Q.-X., Feng, Z.-Y., Li, Z., Wang, M.-X., Feng, X., Liu, F., & Huang, J. (2014) · Rheumatology · doi:10.1093/rheumatology/keu421 · Cited by 25

Intracerebroventricular Administration of an Endothelin ETB–Receptor Agonist Increases Expression of Matrix Metalloproteinase-2 and -9 in Rat Brain

Kōyama, Y., & Tanaka, K. (2010) · Journal of Pharmacological Sciences · doi:10.1254/jphs.10195fp · Cited by 24

Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

Kawamura, K., Takahashi, T., Kanazawa, M., Igarashi, H., Nakada, T., Nishizawa, M., & Shimohata, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098639 · Cited by 23

Protective effects of vascular endothelial growth factor in cultured brain endothelial cells against hypoglycemia

Zhao, F. L., Deng, J., Yu, X., Li, D., Shi, H., & Zhao, Y. (2015) · Metabolic Brain Disease · doi:10.1007/s11011-015-9659-z · Cited by 23

MicroRNA‐31 is required for astrocyte specification

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Role of endothelin‑1 and its receptors in cerebral vasospasm following subarachnoid hemorrhage

Cheng, Y., Li, W., Dou, X., Jia, R., Yang, H., Liu, X., Xu, C., Liu, J., Cao, Y., & Luo, G. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9513 · Cited by 22

MMP-9 expression and activity is concurrent with endothelial cell apoptosis in the basilar artery after subarachnoid hemorrhaging in rats

Guo, Z., Xu, L., Wang, X., & Sun, X. (2015) · Neurological Sciences · doi:10.1007/s10072-015-2092-6 · Cited by 21

Angiopoietin-1 Protects the Endothelial Cells Against Advanced Glycation End Product Injury by Strengthening Cell Junctions and Inhibiting Cell Apoptosis

Zhao, J., Chen, L., Shu, B., Tang, J., Zhang, L., Xie, J., Liu, X., Xu, Y., & Qi, S. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24920 · Cited by 20

Therapeutic Strategy of Targeting Astrocytes for Neuroprotection in Parkinson's Disease

Miyazaki, I., & Asanuma, M. (2018) · Current Pharmaceutical Design · doi:10.2174/1381612823666170710163731 · Cited by 20

Matrix metalloproteinase-9 in the ventricular cerebrospinal fluid correlated with the prognosis of traumatic brain injury

Liu, C.-L., Chen, S. C.-C., Lee, H.-C., & Cho, D. (2013) · Turkish Neurosurgery · doi:10.5137/1019-5149.jtn.8551-13.0 · Cited by 19

Quantitative imaging of tyrosine hydroxylase and calmodulin in the human brain

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Astrocytic expression of cannabinoid type 1 receptor in rat and human sclerotic hippocampi.

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Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage

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Molecular Changes Associated with the Protective Effects of Angiopoietin-1 During Blood-Brain Barrier Breakdown Post-Injury

Nag, S., Manias, J. L., Kapadia, A. N., & Stewart, D. J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9973-4 · Cited by 15

Delayed Progression of Edema Formation Around a Hematoma Expressing High Levels of VEGF and MMP-9 in a Patient With Traumatic Brain Injury: Case Report

Hirose, T., Matsumoto, N., Tasaki, O., Nakamura, H., Akagaki, F., & Shimazu, T. (2013) · Neurologia medico-chirurgica · doi:10.2176/nmc.cr2012-0342 · Cited by 12

Abstract WP254: Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase (CaMKK) Exacerbates Endothelial Cell Impairment After Cerebral Ischemia

Sun, P., Liu, L., Koellhoffer, E. C., McCullough, L. D., & Li, J. (2018) · Stroke · doi:10.1161/str.49.suppl_1.wp254 · Cited by 1

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

Takata, F., Nakagawa, S., Matsumoto, J., & Dohgu, S. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.661838 · Cited by 651

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

Inoue, Y., Shue, F., Bu, G., & Kanekiyo, T. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00640-5 · Cited by 380

Mechanisms of Blood–Brain Barrier Dysfunction in Traumatic Brain Injury

Cash, A., & Theus, M. H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093344 · Cited by 337

Blood-Brain Barrier Overview: Structural and Functional Correlation

Alahmari, A. (2021) · Neural Plasticity · doi:10.1155/2021/6564585 · Cited by 299

Factors influencing the blood-brain barrier permeability

Zhao, Y., Gan, L., Ren, L., Lin, Y., Ma, C., & Lin, X. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147937 · Cited by 291

Roles of astrocytic sonic hedgehog production and its signal for regulation of the blood-brain barrier permeability

(2024) · Vitamins and Hormones · doi:10.1016/bs.vh.2024.04.006 · Cited by 13

Protection of the Blood–Brain Barrier as a Therapeutic Strategy for Brain Damage

Michinaga, S., & Kōyama, Y. (2017) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b16-00991 · Cited by 35

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

Cabezas, R., Ávila, M. F., González, J., El-Bachá, R. D. S., Báez-Jurado, E., García‐Segura, L. M., Jurado-Coronel, J. C., Capani, F., Cardona‐Gómez, G. P., & Barreto, G. E. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00211 · Cited by 481

Mechanisms of Astrocyte Action in the Blood Brain Barrier: From Structural Support to Dynamic Regulation

Feng, D. N., Wang, L. N., Hu, A. N., & Zhang, S. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin45223 · Cited by 11

In Search of the Astrocytic Factor(s) Modulating Blood–Brain Barrier Functions in Brain Capillary Endothelial Cells In Vitro

Haseloff, R. F., Blasig, I. E., Bauer, H., & Bauer, H. (2005) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-004-1375-x · Cited by 301