Cited by 966Protein Hydrolysis and Bioactive PeptidesChemical Synthesis and AnalysisAntimicrobial Peptides and Activities

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BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities

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Minkiewicz, Piotr, Iwaniak, Anna, Darewicz, Małgorzata·2019·International Journal of Molecular Sciences

DOI 10.3390/ijms20235978PMC PMC6928608

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Abstract

The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.

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Authors: Minkiewicz, P., Iwaniak, A., & Darewicz, M.
Affiliations: Chair of Food Biochemistry, University of Warmia and Mazury in Olsztyn, Plac Cieszyński 1, 10-726 Olsztyn-Kortowo, Poland
University of Warmia and Mazury in Olsztyn (PL)
ORCID: Minkiewicz, Piotr
Iwaniak, Anna
Darewicz, Małgorzata
Venue: International Journal of Molecular Sciences
Publisher: MDPI AG
Published: 2019-11-27
Volume: 20
Issue: 23
Pages: 5978
ISSN: 1422-0067 (ISSN-L)
DOI: 10.3390/ijms20235978
PMC: PMC6928608
OpenAlex: W2989775272
Cited by: 958
References: 104
Citations by year: 2026: 161 · 2025: 189 · 2024: 156 · 2023: 160 · 2022: 135 · 2021: 103 · 2020: 53 · 2019: 1
FWCI: 24.15
Type: journal article
Language: en
Open access: gold
dx.doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: International Journal of Molecular Sciences (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
Funders: The project was financially supported by the Minister of Science and Higher Education in the range of the program entitled “Regional Initiative of Excellence” for the years 2019–2022, amount of funding 12,000,000 PLN (010/RID/2018/19)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
Keywords: bioactive peptides, peptide database, food-derived peptides, chronic disease prevention, D-enantiomer, peptide annotation
MeSH terms: Amino Acid Sequence, Amino Acids, Animals, Humans, Peptide Hydrolases, Peptides, Databases, Factual

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BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities

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