Cited by 1,575Fatty Acid Research and HealthAquaculture Nutrition and GrowthEdible Oils Quality and Analysis

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Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life

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Swanson, Danielle, Block, Robert, Mousa, Shaker A.·2012·Advances in Nutrition

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Abstract

Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life. Recently, fish-derived omega-3 fatty acids EPA and DHA have been associated with fetal development, cardiovascular function, and Alzheimer's disease. However, because our bodies do not efficiently produce some omega-3 fatty acids from marine sources, it is necessary to obtain adequate amounts through fish and fish-oil products. Studies have shown that EPA and DHA are important for proper fetal development, including neuronal, retinal, and immune function. EPA and DHA may affect many aspects of cardiovascular function including inflammation, peripheral artery disease, major coronary events, and anticoagulation. EPA and DHA have been linked to promising results in prevention, weight management, and cognitive function in those with very mild Alzheimer's disease.

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Yokoyama, M., Origasa, H., Matsuzaki, M., Matsuzawa, Y., Saito, Y., Ishikawa, Y., Oikawa, S., Sasaki, J., Hishida, H., Itakura, H., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60527-3 · Cited by 2,516
Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial
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Marchioli, R., Barzi, F., Bomba, E., Chieffo, C., Di Gregorio, D., Di Mascio, R., Franzosi, M. G., Geraci, E., Levantesi, G., Maggioni, A. P., et al. (2002) · Circulation · doi:10.1161/01.cir.0000014682.14181.f2 · Cited by 1,311
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Quinn, J. F., Raman, R., Thomas, R. G., Yurko-Mauro, K., Nelson, E. B., Van Dyck, C., Galvin, J. E., Emond, J., Jack, C. R., Weiner, M., et al. (2010) · JAMA · doi:10.1001/jama.2010.1510 · Cited by 764
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Authors: Swanson, D., Block, R., & Mousa, S. A.
Affiliations: Albany College of Pharmacy and Health Sciences (US)
University of Rochester Medicine (US)
King Saud University (SA)
Corresponding author: Mousa, Shaker A.
ORCID: Block, Robert
Mousa, Shaker A.
Venue: Advances in Nutrition
Publisher: Elsevier BV
Published: 2012-01
Volume: 3
Issue: 1
Pages: 1-7
ISSN: 2156-5376 (ISSN-L)
2161-8313
DOI: 10.3945/an.111.000893
PMC: PMC3262608
OpenAlex: W2124111734
Cited by: 1,575
References: 55
Citations by year: 2026: 118 · 2025: 179 · 2024: 163 · 2023: 152 · 2022: 159 · 2021: 164 · 2020: 153 · 2019: 102 · 2018: 100 · 2017: 90 · 2016: 75 · 2015: 51 · 2014: 43 · 2013: 23 · 2012: 3
FWCI: 4.68
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3679 d)
Locations: Advances in Nutrition (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Albany College of Pharmacy and Health Sciences
National Center for Research Resources (KL2RR024136, UL1RR024160)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Keywords: omega-3 fatty acids, eicosapentaenoic acid, docosahexaenoic acid, fish oil, healthy aging, fetal development, cardiovascular function, Alzheimer's disease, inflammation, peripheral arterial disease, anticoagulation, weight management, cognitive function, retinal development, immune function
MeSH terms: Aged, Alzheimer Disease, Cardiovascular Diseases, Docosahexaenoic Acids, Female, Humans, Nutritional Requirements, Pregnancy, Primary Prevention, Eicosapentaenoic Acid, Fetal Development

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Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life

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