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Nutritional Supplements in Support of Resistance Exercise to Counter Age-Related Sarcopenia
Open accessAbstract
Age-related sarcopenia, composed of myopenia (a decline in muscle mass) and dynapenia (a decline in muscle strength), can compromise physical function, increase risk of disability, and lower quality of life in older adults. There are no available pharmaceutical treatments for this condition, but evidence shows resistance training (RT) is a viable and relatively low-cost treatment with an exceptionally positive side effect profile. Further evidence suggests that RT-induced increases in muscle mass, strength, and function can be enhanced by certain foods, nutrients, or nutritional supplements. This brief review focuses on adjunctive nutritional strategies, which have a reasonable evidence base, to enhance RT-induced gains in outcomes relevant to sarcopenia and to reducing risk of functional declines.
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“PS in combination with resistance-type MSE has been identified as an efficient intervention for LM and strength gain in elderly individuals [11,13,15,19,59,64].”
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“As such, the anti-inflammatory effects of n-3 PUFAs on skeletal muscle may be most beneficial to older individuals suffering from sarcopenia [32,50,51] and may complement other strategies, such as exercise and protein supplementation, to combat sarcopenia.”
From Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration (2018) · cites this paper as [51]
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Metadata
- Authors
- Phillips, S. M.
- Affiliations
- McMaster University (CA)
- Corresponding author
- Phillips, Stuart M
- ORCID
- Phillips, Stuart M
- Venue
- Advances in Nutrition
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 6
- Issue
- 4
- Pages
- 452-460
- ISSN
- 2156-5376 (ISSN-L)
- 2161-8313
- PMC
- PMC4496741
- OpenAlex
- W2170406844
- Cited by
- 144
- References
- 102
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 8 · 2023: 9 · 2022: 14 · 2021: 9 · 2020: 14 · 2019: 18 · 2018: 29 · 2017: 17 · 2016: 14 · 2015: 1
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Advances in Nutrition (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (MOP- 123296)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- sarcopenia, resistance training, dietary supplements, myopenia, dynapenia, muscle mass, muscle strength, older adults, functional decline
- MeSH terms
- Aged, Aging, Creatine, Diet, Dietary Proteins, Female, Humans, Leucine, Male, Quality of Life, Valerates, Fatty Acids, Omega-3, Muscle, Skeletal, Dietary Supplements, Muscle Strength, Resistance Training, Sarcopenia
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